Busch Lab

ZMP

dbh

Ensembl ID:
ENSDARG00000069446
ZFIN ID:
ZDB-GENE-990621-3
Description:
dopamine beta-hydroxylase [Source:RefSeq peptide;Acc:NP_001103164]
Human Orthologue:
DBH
Human Description:
dopamine beta-hydroxylase (dopamine beta-monooxygenase) [Source:HGNC Symbol;Acc:2689]
Mouse Orthologue:
Dbh
Mouse Description:
dopamine beta hydroxylase Gene [Source:MGI Symbol;Acc:MGI:94864]

Alleles

There are 2 alleles of this gene:

Allele Name Consequence Status Availability
sa21676 Essential Splice Site Available for shipment Available now
sa24865 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa21676
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000101089 Essential Splice Site 244 614 None 12
ENSDART00000123564 Essential Splice Site None 192 None 11

The following transcripts of ENSDARG00000069446 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 10565416)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 10641282
GRCz11 10 10599520
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCATATCTATCAGCTCCCGCCAAATCTGCCCAAGAACCACATTGTCATGG[T/C]AACTTGAGAGCCACTCGCACATTACAAATAACCTTTCTATGTGAACTTTC
Long Flanking Sequence:
TGATTGGGCATTAAACATTGCTATTTCTAGGCTGATCAGTCAAGCTTTAAATGGGAAAAATATCTGATTATTTAAATTATTTGAGAAATGTTTGAGCAAGATGCTAATGGTCTAATCCTATTCAATGATTTATGCTAAGCTAAGTTAAAGGTGCTCTCACCAGACTTGCAGGTAGGTTGATTGGATTATACAATGGTAAAACTCAACTGTTTACCTAAAGATAATAATAAAATCTTTCCAGGAAGGCACTGTCCACATAATCTACACCATGCTGGAGCATCCCATCCTATCGTTGCATGAGCTCAATATATCCCGTCTCCAGCCTGGCGTCCAGCGAGTCCTGCTCCTGCGTCCAGACACCCCGTCCCCCCATCTCCCGAAAGATGTACGCACCCTGGAGGTCCTGGCCCCTGATGTCATCATCCCCACACAAGAGACTACTTACTGGTGCCATATCTATCAGCTCCCGCCAAATCTGCCCAAGAACCACATTGTCATGG[T/C]AACTTGAGAGCCACTCGCACATTACAAATAACCTTTCTATGTGAACTTTCAGAATGTTGTACCTATATAATTGAAGCATGTGAGGTACTTTGACCAATTATAATGCTCTTCAGTAAAACGCTAATGTAAGTGTGGGGTTATGGAAACTGAATCTGAATATAATTAGACTGAGTATGTGTGCGTTGGTGGTAAAGTGCTTGTGGAAGAGGCCTTCAGCCGCTTCTTTAGATGTGATGGTTTCAGGGTTTTACATGGAGGTTGGCAGCTCATTCCACCAGAGAAGAACAGAGAGGGTAAAGGTTTTCCTCACAATGAAGGAACAACAATGTTACAATGTAACAATGTTAACAATGTCAGTGACCTTAAATGCACAATGTAGAACTTATTGTTGTGTTTGAAGGCCATTTCACATTACACCAACACAAACCAACCTACCCTGCAGGCACAGGATGTCAACATGACGTCCTATTGACGTTGTACCCCAACGTATCCCAATGTCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24865
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000101089 Essential Splice Site 517 614 10 12
ENSDART00000123564 None None 192 None 11

The following transcripts of ENSDARG00000069446 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 10539265)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 10615131
GRCz11 10 10573369
KASP Assay ID:
554-7864.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCCACGTGGACACAGATTACCTGCAGAAATACTTCAGCCTCATCAACAG[G/A]TACAAAACACACACAACAACTACAGCAAACACAACCTTCCCCCGGTGAAG
Long Flanking Sequence:
CCTTTTATTTTATTATAACAATCATTAAATTTCAAAACTGCATAGAAAACATCAATAAAGGAACATTAAGGGGTACGTTCACCAAAAAAAAAAAAAAACAACAACAACAACAAAATAATCATTATCATTTACTCACCCACTTATATCATTCCAAACCTGTATGGCTAAATCAAAATGAGAAACAGCAAATCAAGTAAAGAGAAACTAAAGACTGACAGAAAAAGCATCATAACCTGTGCATTATGTTCTTATGAAGCCATTACTGTCAGTGTTGGAAAGAAATAATATATTACAATTTCTATCCAAACACTGATTACTGTATATATGAAAACACACTTCAAACCCATTGGCTACGCATTCTCTCATCCACAGGGTGGTTTTGGAATTATGGAGGAGATGTGCGTCAATTACGTCCATTATTACCCCCGAACGCAACTTGAGCTGTGCAAAAGCCACGTGGACACAGATTACCTGCAGAAATACTTCAGCCTCATCAACAG[G/A]TACAAAACACACACAACAACTACAGCAAACACAACCTTCCCCCGGTGAAGTCCAAAACACTTTCCAGACACTCTTTCATGAAAACCTTGAAAACATCAACAACAAACTGCAAACCTGAAACTAATGTCTGGCTTCAAGACTAACAGCCTGAGGACGAGAGGAGCACTTTCAATTCCTGCATCAAATCAGTCGGAAAAACAACCAAATATGTTTTCTTCTGCAATGCATAAACAAAAGAAAAGGCGATGGCATTTGTATTCATACATTTGGCGGCGACAAATTGCATTTTTCCAGCTTGTTTCTGTGACACTCCATATAGTGAAATCAGCCAATTCTGAAAGTCAAAAGACACTGCAGATGAATACCGTAGGTTTAAAAAAAATAATAATTTTATTATCATACTTCCCCAGTTGATTGTCAAGAATTTTTATGCAAATTAGTCATTGTTTTTAGCACAAAAATCTTACATTTAATGTTATTTTGACATATCAGAGTCAAAT
Associated Phenotype:
Not determined