ZMP
xrn2
Ensembl ID:
ZFIN ID:
Description:
5'-3' exoribonuclease 2 [Source:RefSeq peptide;Acc:NP_001001944]
Human Orthologue:
XRN2
Human Description:
5'-3' exoribonuclease 2 [Source:HGNC Symbol;Acc:12836]
Mouse Orthologue:
Xrn2
Mouse Description:
5'-3' exoribonuclease 2 Gene [Source:MGI Symbol;Acc:MGI:894687]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa37162 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa17318 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa37162
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000100239 | Essential Splice Site | 356 | 540 | 11 | 18 |
| ENSDART00000100246 | Essential Splice Site | 356 | 952 | 11 | 31 |
| ENSDART00000137314 | Essential Splice Site | 80 | 273 | 3 | 9 |
| ENSDART00000146596 | Essential Splice Site | 356 | 540 | 11 | 32 |
Genomic Location (Zv9):
Chromosome 20 (position 49008408)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 20 | 49044874 |
| GRCz11 | 20 | 48876091 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTTTGTGGGAAATGACTTCTTGCCCCACTTACCGTCTCTTGAGATCAGG[T/C]ACGCTCCCAAAAACACTTTATCTCTTCTGTATGCTCTGCAGTGAGTCTGA
Long Flanking Sequence:
ATTGGTTAATTTAATAACCAAGTACATATCTTTATTAGGTTAATGTTAAATGTTTGCATGTGCAAAAGCTTGCATGTGCAAAAACGGTACTGAACGTTTGGTAATAAACATTTTTTAATACCCACACTTGTATACCCACACTGTTGTGAATTAGTCTTTAAAAGTTTGTATTAAGCAAAATTTTTACATTTTATCTAAGAAAAAGTGCACGTTAAAGCATAAAGAATGTTAATCTGTGTGTAAAACAAACATTGTTTAATACCCATACTTGAATTAGTCTTTAAAAATCTGTATTAAACTAGAAAAAGTGCATGTAAAAGCATAATGAATGTAATTTTGTTAGTAATGTGTGTTTTGTTGTGCAGTATCTGGAGAGGGAGTTGACAATGGCCAGTCTGCCGTTCCCGTTTAGCTTTGAGCGGAGCGTCGACGACTGGGTGTTCATGTGTTTCTTTGTGGGAAATGACTTCTTGCCCCACTTACCGTCTCTTGAGATCAGG[T/C]ACGCTCCCAAAAACACTTTATCTCTTCTGTATGCTCTGCAGTGAGTCTGACTCTGGTTTGTTTTTAAACAGAGAGGGCGCCATCGATCGTCTGGTTGGCATCTACAAAGATGTTGTGCATAAAACTGGGGTGAATATTTCCATATGTCTCGTAGCAGAATTGAATTTATTTTCAGGGTTCCCAAGGGTCGTGGAGTTTTAAAAGGTCTGTTCCAGACATCGAAAGTCAGGGAATTTTATATATAATTTTTGTTCAAGTCATAGAATATCAGGGCTTTTAGGTTTGTCATTTTTATATTTTACTTATTTAGCAATGTATATATATTTTTTCTGTACCATATATTTTATTTAGTGTTTCACCTTTTGCCTATTGTTATGGCTAATCTATTTTTGTTGTGGTTTATTATTATTATTATTATTATTATTATTATTATAAAACAATAATAATTAGTATTATTACTATGATTATTACTATTGTTGCTATTATTTGATTATTACTAT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa17318
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000100239 | None | None | 540 | None | 18 |
| ENSDART00000100246 | Nonsense | 721 | 952 | 24 | 31 |
| ENSDART00000137314 | None | None | 273 | None | 9 |
| ENSDART00000146596 | None | None | 540 | 25 | 32 |
Genomic Location (Zv9):
Chromosome 20 (position 49038968)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 20 | 49014314 |
| GRCz11 | 20 | 48845531 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CAGTCARTAATTTCCCAATCTTTCTCTTYAAGGCCACTGAGATCCCTGCA[G/T]AGTTTTGTCRTGGAATCCAAGGTATATTAAATCTTGATGAAGACCCTATT
Long Flanking Sequence:
CTTTTTTTTTACTTATTTATTTTCATCTAATTTATTTATTTTTTATTTAATAATTTTCATTATTTAATTTATTTTCATGTAATTATATTTTTGCTTATTTTCATTTATTTTTATTTATTTAATTGTATTTTTTTCATTTATTGATTTTCATTTATTTTTATTTATTTAATTGTATTTTTTTCATTTATTGATTTTCATTTATTTTATTTCTCATTTTATTTATTTTCATTTATTTTTATTGTATTTTCATTTGTTTTCATTTATTTATTTATTTTCATTTATTTTTATTGATTTAATCTTATTTATTTTAATTATTTTTTTATTTAATTTTGTTTATAATGATCTCAATTTTAACCTGATTTGATTTATTACCTAAATAATAGATTTATTTGTACTAGTGTAAATAAATGATACTTATATTATTATATATATTATTATATATTAGCTTGTCAGTCAGTAATTTCCCAATCTTTCTCTTCAAGGCCACTGAGATCCCTGCA[G/T]AGTTTTGTCATGGAATCCAAGGTATATTAAATCTTGATGAAGACCCTATTCTACCAGATAAGTAAGGAGACGACACGTTTATCTTTTGTTTCTTGATGCTTTTCTGTGTTTTCATTACTTGGGCTGTGTCTGTTGAGGCACTTGAGAGTTAAGCTTTTCAAATCCTGTGAAACATGGCTTTTGTTCTCCTCAGACTAGTGGAGTCTCCAATCCCAGTGCTGAGAGACATCAGTAGCAACTGCGCTATTGGGTAAGAGTTTGCTTTGTGTGGAGCTTTGAAGTGCTTTTCTCTTATTTATATATTTTTAAATGGTAAATTTTATGTTTAGCTATTTAGCTAATTTTTTAGATTTGATTTTATTTGCTTTTAGATTTAATTTTTTATATCAAATTATATATTTTAGACAATTATTTTACATTTATTTTATATTTACTTTTATATTTTATACTGTTTACTTAAATTTAATTCTATTTAATTTTATATTTAATTCTATTTTATT
Associated Phenotype:
Not determined