Busch Lab

ZMP

cyp7a1a

Ensembl ID:
ENSDARG00000069018
ZFIN ID:
ZDB-GENE-040426-1296
Description:
cholesterol 7-alpha-monooxygenase [Source:RefSeq peptide;Acc:NP_957467]
Human Orthologue:
CYP7A1
Human Description:
cytochrome P450, family 7, subfamily A, polypeptide 1 [Source:HGNC Symbol;Acc:2651]
Mouse Orthologue:
Cyp7a1
Mouse Description:
cytochrome P450, family 7, subfamily a, polypeptide 1 Gene [Source:MGI Symbol;Acc:MGI:106091]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa32901 Nonsense Mutation detected in F1 DNA Not yet available
sa38326 Nonsense Mutation detected in F1 DNA Not yet available
sa32900 Nonsense Mutation detected in F1 DNA Not yet available
sa19734 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa32901
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000100069 Nonsense 100 558 2 6
ENSDART00000145188 Nonsense 54 512 2 6
Genomic Location (Zv9):
Chromosome 2 (position 21948927)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 22494342
GRCz11 2 22152404
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGGCTGGATTCCCTTCCTTGGCTGTGCTCTTCAGTTTGGGGCAAATCCTT[T/A]AGAGTTTCTTCGCAGCAGACAGAAGAAGCATGGCCATATTTTTACATGCA
Long Flanking Sequence:
ACGTTTTCAGCAAGTAGCGTGGTGGGCAGTCTTCAATTATGGAATTACAGTACGTCAGAGGCTGTGGCTTGCGGCTTGTGGTGAATCATATAAAAACAGTGCTGAGGGCATTTGTCTGTATCCTCAAAGAATACAGTCAAGCTCTACTTCCACCTGATTGTGTCTCACTAGCAGTCATGATCCTAACCATTTCCTTCATTTGGGCCATAGTGGTTGGTCTTTGCTGTTGTCTTTGGCTTATTACAGGAATACGCAGAAGGTAAAAACTCACAGATTTGTGACTAAAAGTTTTGTAAAGTTTGGGGATATCAGTGAGTTTATTGAAGATATAGAATTAGTAAATTTAACCTAGAGTATGTGCCTACAGGAGTGAACTTTGTTCTTAAACTGTGGTTTGTAATTGTTTAATGCTGTGTGTTTCAGACATCCTGCAGAGCCTCCATTAGAGAATGGCTGGATTCCCTTCCTTGGCTGTGCTCTTCAGTTTGGGGCAAATCCTT[T/A]AGAGTTTCTTCGCAGCAGACAGAAGAAGCATGGCCATATTTTTACATGCAAGATTGCTGGGCAGTATGTTCATTTCCTTTGTGATCCATTCTCCTACCATGCTGTCATCCGTCAAGGAAGGCACCTTGACTGGAAGAAATTTCACTTTGATGCCTCTGCGAAGGTAAATGAAATAACATTTGCTATGCTATGTTATATGCTACAGCAATATAACTTTTAGATTAGCATGAGATGACGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCCTTGTAGGCATTTGGTCATGAGAGCATGGATCCCAGTCAAGGTTACACCACTGAGAATTTGCATCAGACTTTCCTGAAGACCCTGCAAGGGGATGCCTTGTCTTCTCTAATCGAGACCATGATGGAAAACCTCCAGGGCACCATGCTGCAATCTGGAATGTTGAAGGCCACAACCTCTGAATGGCAAAGTGATGGTATTTACGCCTTCTGCTACAAGGTCATGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa38326
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000100069 Nonsense 154 558 2 6
ENSDART00000145188 Nonsense 108 512 2 6
Genomic Location (Zv9):
Chromosome 2 (position 21948766)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 22494181
GRCz11 2 22152243
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTCAAGGAAGGCACCTTGACTGGAAGAAATTTCACTTTGATGCCTCTGCG[A/T]AGGTAAATGAAATAACATTTGCTATGCTATGTTATATGCTACAGCAATAT
Long Flanking Sequence:
GTCTCACTAGCAGTCATGATCCTAACCATTTCCTTCATTTGGGCCATAGTGGTTGGTCTTTGCTGTTGTCTTTGGCTTATTACAGGAATACGCAGAAGGTAAAAACTCACAGATTTGTGACTAAAAGTTTTGTAAAGTTTGGGGATATCAGTGAGTTTATTGAAGATATAGAATTAGTAAATTTAACCTAGAGTATGTGCCTACAGGAGTGAACTTTGTTCTTAAACTGTGGTTTGTAATTGTTTAATGCTGTGTGTTTCAGACATCCTGCAGAGCCTCCATTAGAGAATGGCTGGATTCCCTTCCTTGGCTGTGCTCTTCAGTTTGGGGCAAATCCTTTAGAGTTTCTTCGCAGCAGACAGAAGAAGCATGGCCATATTTTTACATGCAAGATTGCTGGGCAGTATGTTCATTTCCTTTGTGATCCATTCTCCTACCATGCTGTCATCCGTCAAGGAAGGCACCTTGACTGGAAGAAATTTCACTTTGATGCCTCTGCG[A/T]AGGTAAATGAAATAACATTTGCTATGCTATGTTATATGCTACAGCAATATAACTTTTAGATTAGCATGAGATGACGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCCTTGTAGGCATTTGGTCATGAGAGCATGGATCCCAGTCAAGGTTACACCACTGAGAATTTGCATCAGACTTTCCTGAAGACCCTGCAAGGGGATGCCTTGTCTTCTCTAATCGAGACCATGATGGAAAACCTCCAGGGCACCATGCTGCAATCTGGAATGTTGAAGGCCACAACCTCTGAATGGCAAAGTGATGGTATTTACGCCTTCTGCTACAAGGTCATGTTTGAAGCAGGCTACCTGACCCTCTTCGGAAAGGAACTGGATGGGGACCAGAGCATTGCACGTCAGCAGGCCCAAAAGGCTCTGGTGCTCAATGCTTTGGACAACTTTAAAGAGTTCGATAAGATCTTCCCAGCTCTGATCGCTGGGCTCCCCATTCATGTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32900
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000100069 Nonsense 213 558 3 6
ENSDART00000145188 Nonsense 167 512 3 6
Genomic Location (Zv9):
Chromosome 2 (position 21948468)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 22493883
GRCz11 2 22151945
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGGGCACCATGCTGCAATCTGGAATGTTGAAGGCCACAACCTCTGAATG[G/A]CAAAGTGATGGTATTTACGCCTTCTGCTACAAGGTCATGTTTGAAGCAGG
Long Flanking Sequence:
TCCCTTCCTTGGCTGTGCTCTTCAGTTTGGGGCAAATCCTTTAGAGTTTCTTCGCAGCAGACAGAAGAAGCATGGCCATATTTTTACATGCAAGATTGCTGGGCAGTATGTTCATTTCCTTTGTGATCCATTCTCCTACCATGCTGTCATCCGTCAAGGAAGGCACCTTGACTGGAAGAAATTTCACTTTGATGCCTCTGCGAAGGTAAATGAAATAACATTTGCTATGCTATGTTATATGCTACAGCAATATAACTTTTAGATTAGCATGAGATGACGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCCTTGTAGGCATTTGGTCATGAGAGCATGGATCCCAGTCAAGGTTACACCACTGAGAATTTGCATCAGACTTTCCTGAAGACCCTGCAAGGGGATGCCTTGTCTTCTCTAATCGAGACCATGATGGAAAACCTCCAGGGCACCATGCTGCAATCTGGAATGTTGAAGGCCACAACCTCTGAATG[G/A]CAAAGTGATGGTATTTACGCCTTCTGCTACAAGGTCATGTTTGAAGCAGGCTACCTGACCCTCTTCGGAAAGGAACTGGATGGGGACCAGAGCATTGCACGTCAGCAGGCCCAAAAGGCTCTGGTGCTCAATGCTTTGGACAACTTTAAAGAGTTCGATAAGATCTTCCCAGCTCTGATCGCTGGGCTCCCCATTCATGTTTTTAAGAGTGCCTACAGCGCTCGTGAGAAACTTGCCAAGACTATGCTCCATGAGAACCTCAGCAGGCGTGCCAATGTGTCTGATCTCATCTCCTTGCGCATGCTTTTGAACGACACACTATCTACCTTCAACGAGCTGAGCAAAGCCCGGACCCACGTCGCTATACTTTGGGCTTCACAAGCCAACACTCTGCCTGCAACCTTCTGGACTCTGTTCCACATGATCAGGTAAGACTCATACTTAAACTGTACAGTAGTCACTTTTAAGGGTTATCAAACAGCACAGATAAATATGTTAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19734
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000100069 Nonsense 259 558 3 6
ENSDART00000145188 Nonsense 213 512 3 6
Genomic Location (Zv9):
Chromosome 2 (position 21948331)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 22493746
GRCz11 2 22151808
KASP Assay ID:
2259-1896.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCAGAGCATTGCACGTCAGCAGGCCCAAAAGGCTCTGGTGCTCAATGCTT[T/A]GGACAACTTTAAAGAGTTCGATAAGATCTTCCCAGCTCTGATCGCTGGGC
Long Flanking Sequence:
ACCATGCTGTCATCCGTCAAGGAAGGCACCTTGACTGGAAGAAATTTCACTTTGATGCCTCTGCGAAGGTAAATGAAATAACATTTGCTATGCTATGTTATATGCTACAGCAATATAACTTTTAGATTAGCATGAGATGACGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCCTTGTAGGCATTTGGTCATGAGAGCATGGATCCCAGTCAAGGTTACACCACTGAGAATTTGCATCAGACTTTCCTGAAGACCCTGCAAGGGGATGCCTTGTCTTCTCTAATCGAGACCATGATGGAAAACCTCCAGGGCACCATGCTGCAATCTGGAATGTTGAAGGCCACAACCTCTGAATGGCAAAGTGATGGTATTTACGCCTTCTGCTACAAGGTCATGTTTGAAGCAGGCTACCTGACCCTCTTCGGAAAGGAACTGGATGGGGACCAGAGCATTGCACGTCAGCAGGCCCAAAAGGCTCTGGTGCTCAATGCTT[T/A]GGACAACTTTAAAGAGTTCGATAAGATCTTCCCAGCTCTGATCGCTGGGCTCCCCATTCATGTTTTTAAGAGTGCCTACAGCGCTCGTGAGAAACTTGCCAAGACTATGCTCCATGAGAACCTCAGCAGGCGTGCCAATGTGTCTGATCTCATCTCCTTGCGCATGCTTTTGAACGACACACTATCTACCTTCAACGAGCTGAGCAAAGCCCGGACCCACGTCGCTATACTTTGGGCTTCACAAGCCAACACTCTGCCTGCAACCTTCTGGACTCTGTTCCACATGATCAGGTAAGACTCATACTTAAACTGTACAGTAGTCACTTTTAAGGGTTATCAAACAGCACAGATAAATATGTTAATTGTATTGGCGGAGATAAGAATGACCTTGAAGAGTTCTTTGAAAATACTACAGACTCGTTAGAATGATAGGTTTTCTCGAAGAATATGTATGACATGTACTTATTATGATGAATGTTCTGCTTGTTTGTAGGTGCCCT
Associated Phenotype:
Not determined