Busch Lab

ZMP

hfm1

Ensembl ID:
ENSDARG00000068922
ZFIN ID:
ZDB-GENE-061207-43
Description:
Novel protein [Source:UniProtKB/TrEMBL;Acc:A2BIH3]
Human Orthologue:
HFM1
Human Description:
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:20193]
Mouse Orthologue:
Hfm1
Mouse Description:
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae) Gene [Source:MGI Symbol;Acc:MGI:3036246]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa19742 Nonsense Available for shipment Available now
sa44531 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa32909 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa19742
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099851 Nonsense 408 1049 11 29
ENSDART00000141518 Nonsense 533 977 14 26

The following transcripts of ENSDARG00000068922 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 23002243)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 22887671
GRCz11 2 22543322
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACAACAGCAACTGCAGTAATCATGACACGGCCTCAGACAAAGGACAAATA[C/A]ATGCATTTCTTGAGTGGCTTAGACTGCATAGAGAGCAGGTATACACCTAA
Long Flanking Sequence:
TGACTTGCCAGTTTTATGTAAGCTCTGCAACTTTATTTTCACTTATTTACTTCTGATTACACATTATTCAGTATGCATTATTATAGATATAATATATATATATATATATATATATATATATATATTTATTATTTTTTTTTTTTATATATATTTTTAGTTACAACAAGTACTCTAGCCATGGGTGTGAATATGCCAGCCCACCTTGTGGTAATCAAATCCACAATGCACTATGTTGGTGGTGCATGTGAGGAGTACAGTGAAGCTGACCTGTTACAAATGATTGGAAGAGCTGGCAGACCACAGGTACTATTAACAAATGTTAATATTATTACAAACACAAAGTGCCAGCTCTAAAAGCAGAGTTGTTAGTAGTAAAACACAAAATCTCAGCTAGTTACAGTATTCAGATTTGGACAATAATCACTTGCTTTGGTTTTTGTTTAGTTTGACACAACAGCAACTGCAGTAATCATGACACGGCCTCAGACAAAGGACAAATA[C/A]ATGCATTTCTTGAGTGGCTTAGACTGCATAGAGAGCAGGTATACACCTAATCACATTTTGTTCTGTTAGAAATTTTAGTTGCATTTTCTGTTCTTTTTAAATAGATCTTATTAACAGGTTGATTTATTTGTTACTTATGGATTTGACAAGTACAACAAAATAAACATTTTTCAGTTTGCATACAAATCTGGTGGAGCACTTGAATGCAGAAATAGTTCTTCACACCATATCTGATGTGAACATGGCTCTGGACTGGATCCGCTCTACTTTCCTGTACATCCGTGCTTTGAAAAACCCCAAACACTATGGTAAACCTTAAACCATGAGTACACTGAAGATACAGACATCAGCCAAAGCTCTTCTTTATTAGCCTCTCATTTCACAGGCTTTCCCCCTGAGGTTGACAAATGTGGAATTGAGACTAAATTACAAGGTATGAAAATTAATAAATTAAATCGTGAATCAGTTGTTGTTCAATGGCTAAAGGCTGATTTATACTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44531
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099851 Essential Splice Site 778 1049 22 29
ENSDART00000141518 Essential Splice Site 887 977 24 26

The following transcripts of ENSDARG00000068922 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 22994025)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 22895889
GRCz11 2 22551540
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTATTGTTGGAGATTGTGACAATAAGGTGGTCTTCCAACAAAAAATCTC[G/A]TAAGTTCTATGTTATTTATTTGTCTTTAGCAAACCTTTTTTTTTTTTTGA
Long Flanking Sequence:
GGGCTGTTGCTGGGCACTGCTGTTTCAATAGGACGTTCTTTTGAGTGTAGCCTCTTGGTGATTCAACACTCTTTGCTCAATGTCATTAGCTCATTTTTGGCGGAAGTGGCGTTTAGTGGCTTTTGCATCTGAACTTTTCAAGTGTTTGCATGATTATACAGACAAAGCAGAATCATATAAGTAAATATCAGTTTGCAACATGAAGCAGCATAATGAGCAGTTTTTAACGTCTTAAAATAAATGGAACTGAATGAGACCGGAAGTCTCGAGCCAAAAAGATTTTAAATTGCGCCCGCTCGAACACAAAGAATAAGGCGAAAATAATGTAATAATTTCTTCTAGATTCCACGATACAGTCCATCCACAGCTGAGATTGTTTTCACAGTCAACATGAATAACTTTAAGGAGTTGGCACTGAAGCGGACAGCGCCAGACCACCATTATGTCACTCTTATTGTTGGAGATTGTGACAATAAGGTGGTCTTCCAACAAAAAATCTC[G/A]TAAGTTCTATGTTATTTATTTGTCTTTAGCAAACCTTTTTTTTTTTTTGAACGATGGAAGCAATGCATGTTTTTCTTTTAAGGGACACTTTGCTCTTGAAGTCTGGGAGCTGGTCAAAGAGAATTGAGGTGACAAGATCACCAAAGGGAGAGGAGCTCAGCATTCATTTGATAAGCTCTGAATATGGTCAGTGGTCATATATTATGTCTGACAAACACTTAAACAAGTCATAATGGTTTTTGGATGCTCACATTTCAGTAACATATATATTTGACCTACACAGAAACATACAGAGCGATCTGATTACAGATTTCTATTATTATTGTAGAGTGATGAATATGTGTTGATTGTGTAGTGGGTCTGGACATACAGCAGGACTACAGCGCCCACTACTCAGGAGTGCACGGTTTGCAAGCTGAGTTCTCCATTACAGAGAAACCAACATGGAGATTTCAGAGGATTCATGACACAATGAAGAAGAGACAAGGCCCCACAGTCGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32909
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099851 Nonsense 905 1049 26 29
ENSDART00000141518 None None 977 None 26

The following transcripts of ENSDARG00000068922 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 22987586)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 22904241
GRCz11 2 22559892
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCATGCCATTTCTTTTTTTAGGCAAAATTGGAGTCAAAAGGACTGTACTA[C/T]AGTCAAATGTCTCCTCATACCTTGACAACCTAAAAATGAGGAATGAGAAA
Long Flanking Sequence:
GAGCAGTGGGTGTTCCAAAGTTAGTGTACAGTGAGTAGCTACTGTCTGGTCTAATCATCACTTATTTAAACTCGCCTGACTCCCTTGATGTTCTGCTACCTTCTTTGCATTCTTTCTCACCTGTCATCCCCTTATCACCTCTCATCCATGGTCTCCCTCCTGCAAACAAAAGACTCTAAAATATATCCATATCACTGCCTTCTGGCATAATCAGTGCATTTCTAAATAAAACCATTAAGAATTACTAAATGGCTTAAATAACATAGTAATGTTCGACGGTTATATTCAAATTCATATAGACATTCTCTTCGTGGATCAAGTTGCTCCAAACATGGTTAAGAGAAATTGCCATCATCTCTGCAAAAACAAAGAGCTCTGTAGACATGACTGCTGTGAGTACAAGAGGTTTTAGGTGATCCTAGACTGCTCTCATTGTCTGTACTGGTTCATTCATGCCATTTCTTTTTTTAGGCAAAATTGGAGTCAAAAGGACTGTACTA[C/T]AGTCAAATGTCTCCTCATACCTTGACAACCTAAAAATGAGGAATGAGAAACTTTGTGAGACTCCTGTGAAGCGATTGAAGGTCAGAATTCTTATGATCAGGGTTACATTTACACAACGGTCAGAAAATGTAATTCATTATATCCTAATAGTTCAGCTGCATGGCAAGATTTTGTTTTGTAAGATATACTGTATTTTCAATTGAGTTTTGACTTTTTCTTTAGATGATGATGAATAATGGCACAGCAGCTGTAAGCATGCAGCAGTTCTCCTACAAACCCAAAGACACACATTCTGCTGCCAAGAGGTACTCCAGTGTTTCTATTATTAAACTTTAAGTTAACCTAAAAACAAAACTGACTCACTTTTAGTCGTTCCAAATCCCTGTGACCTTCGTTTAATATTTGAAACAAAAATTAACATATTTTAGGTGAAATAGCTGAGAGCTCCGTCATCCCCTATAGACAGCATGGATTCAGACTCAAAAAAAAAAAAACAACTT
Associated Phenotype:
Not determined