Busch Lab

ZMP

gpx4a

Ensembl ID:
ENSDARG00000068478
ZFIN ID:
ZDB-GENE-030410-2
Description:
glutathione peroxidase 4 [Source:RefSeq peptide;Acc:NP_001007283]
Human Orthologue:
GPX4
Human Description:
glutathione peroxidase 4 (phospholipid hydroperoxidase) [Source:HGNC Symbol;Acc:4556]
Mouse Orthologue:
Gpx4
Mouse Description:
glutathione peroxidase 4 Gene [Source:MGI Symbol;Acc:MGI:104767]

Alleles

There are 2 alleles of this gene:

Allele Name Consequence Status Availability
sa9384 Nonsense Mutation detected in F1 DNA Not yet available
sa8646 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa9384
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099056 Nonsense 10 112 3 7
ENSDART00000144031 Nonsense 10 112 3 7
ENSDART00000147423 Nonsense 10 112 4 8

The following transcripts of ENSDARG00000068478 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 22 (position 17816371)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 17567306
GRCz11 22 17592284
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AAACTACTCTCAGTTTGCAGAGATGCACGCCAAGTACTCTGAGAGAGGTT[T/A]ACGCATCCTGGCTTTCCCTTCCAACCAGTTCGGACRTCAGGTATGGACAT
Long Flanking Sequence:
TATCTTTTTATGTCTGATGTAGTATGTAAATCTTCTTTTGTAATTGTTTTATCTCAAATTTATAACTCACCACCCCATAAAAGTCATATTCATGGTCAACGGTTTAAAGTTTTTGTTTTTACATGAGACTTCTGTAGATTTCACAGAGAGTTGAGTAGTGTATGATTCTTTTTTTTCTTTACTTCAGACTATTAAATTGGAGGATATCAAGCATGTTTTATATTTTGCACCAATTTTTGTACACATAGTTTGCATCTTCTAGCAGCTAAAACCAAATTGTTGTGTTAGAAACAACTTAATCATCACAATGTTACAGTATTTTAAACCTTTTGGCATATTATTTCTTGCTCCAATGACTTTGTGACACTAATTTACTTTCATATTTACATACTTCAGGGGAAAAGTTGTGATCATCACAAACGTTGCCTCCAAATGAGGTAAAACCCCAGTAAACTACTCTCAGTTTGCAGAGATGCACGCCAAGTACTCTGAGAGAGGTT[T/A]ACGCATCCTGGCTTTCCCTTCCAACCAGTTCGGACGTCAGGTATGGACATCAAAAATGCTCAACTATTTTTGTAAATAGGCTCATTTTACAAATCATCTAAAGTTAAAGTGCTGAGTTTTACCATTTTTGAATCCATTCAGCCAATTTACATGTCTGGCGGGAGCATTTTTAGCTCAGCTTAGCATAAATCATTAAATCGAATTAGACCATTTGCATCTCACTTAAACATTTTTTTTTAAGTTTTGATAATTTTTCTATTTTCTGCTTTAATCTTTTGTTGATGGAATATTAAAAGTTGCTTTAAATAGAAAAATTATCAAAACTCCTTTAAACTTTTTTTTGAATGAGATGCTAATGGTTTAATCTGATTTAATGCTAAGCTAAAAGTGCTTCTACCAGACACAGAGATCGGCTGAATAGTTTGTTTAACTGTAGAGGAGTTGTAAAATGAGTCTATTTCCAAACAAAAGTGCATTTATTTAATGTTTTTAAAGTTAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8646
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099056 Nonsense 111 112 7 7
ENSDART00000144031 Nonsense 111 112 7 7
ENSDART00000147423 Nonsense 111 112 8 8

The following transcripts of ENSDARG00000068478 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 22 (position 17813964)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 17564899
GRCz11 22 17589877
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AACTGTCTYTAAATATAATTTCAGGTGGTGGAGAAGGATCTTTCTAAATA[T/A]CTCTAATGTGCTGGATGAGCTGAACTAGCGTCTGAGCGCTGGGTGTGAGT
Long Flanking Sequence:
ATTTTGAGTTGAGACAGCTCAAACATGCAATTTAATCTTGACTAGCCTTAAACCTTGTTTGTGAAACCGGGGGTTAGAATTATGATTTAAGCAAATTATCACAAATTAAAATTAGGATTAAAAATTGTAAATTCAACAAGGCTGACTTTTTTTGTTGTTACAGTGGCATCAAATGGAATTTCACAAAGGTTTGTACATTTCTTTTATAGACAAATTACTGTTTTAAATTTATTAAAATAAATTAATAAATCCAAATAAATGATTACTATTCATTATAATTAATTAATCATTTTCCTTTTTGTCTAAATGTCAGTTCCTTATTAACCGTGAAGGCCAGGTTGTGAAGAGATACTCCCCACTGCAGGATCCAAGTGTACGCTTCTCATTCTCTTCTCATCTTTAATTATATCTACATCTGTTTAAAGTCATGAACTATATCATCATGTAAGTAACTGTCTTTAAATATAATTTCAGGTGGTGGAGAAGGATCTTTCTAAATA[T/A]CTCTAATGTGCTGGATGAGCTGAACTAGCGTCTGAGCGCTGGGTGTGAGTGATGCCGCTCATGGACTGATGAAGGTTTGTTTGGAAACCCCTTGTTGAGGAAAGAACAGACCTGATGTGTTTGGCGTGCACCTCCTCCTGAGGGCATCACGAGTGCTCAGCGTCAGTCCGCAGAGAGGACAGATGAAGAGACATGCTTTTTATTAGCACTAAACATGCTGATGTAGTGTACATTTATTAATAAATGCAAAGAGATTCTGCTGAACAGTACGTTTGGTGTTTGTTTTCTTCCTGTAAGCCAAGGTATTGTTGAGTTTTATAGTGTTTTTTTATTTAATTTGTATTTGTTTTATTAAGTAGTTTGTTAAAGTTTTAGTAATTTTATTGATCCTTTTTATTAAGTTTTATTTTTTATGTCTGTTCTAGTTATTTTAATAAGTTAAACAGAACGAAAATTAGAAATGGGAATGTTGAAATGTGAGTATATGTATGTAAATATTT
Associated Phenotype:
Not determined