Busch Lab

ZMP

ENSDARG00000068026

Ensembl ID:
ENSDARG00000068026
Human Orthologue:
PRKG1
Human Description:
protein kinase, cGMP-dependent, type I [Source:HGNC Symbol;Acc:9414]
Mouse Orthologue:
Prkg1
Mouse Description:
protein kinase, cGMP-dependent, type I Gene [Source:MGI Symbol;Acc:MGI:108174]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa41301 Nonsense Mutation detected in F1 DNA Not yet available
sa31686 Nonsense Mutation detected in F1 DNA Not yet available
sa25410 Nonsense Mutation detected in F1 DNA Not yet available
sa1566 Nonsense F2 line generated Not yet available

Mutation Details

Allele Name:
sa41301
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000098135 Nonsense 8 481 1 13
Genomic Location (Zv9):
Chromosome 8 (position 53208142)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 50950859
GRCz11 8 50939881
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCTCTCTGTGTCCTGTTATCCAGGGGCTCATGGGGACCCTCAGAGATCTT[C/T]AATTCGCACTTCAGCTGAAGATTGAGGAGTTACGGCAGAGAGATGCTCTT
Long Flanking Sequence:
GTGGAGAATATCATTACCTGTAAATGTAGGCTATGCATTAGAATGAGCTCTGCCCACTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCCCTCTCTCTCTCTCTCACACACACACACAGATCTCGGCGCGTGCTGCGAGGAGACATGATTCAAATTCACACTGTGGATTTCTCCAGTACTCCAGAAGCTGACCAGCTGCATCCTTCTACAAGAGAATCGCCACAAAATCCCCATCTTTTATCGCATTATCCAGGTAACTGTCGTCTTCACATAAAAATAAAAACAAAAGTGGCTTAATCTATTTGCTTGTACGTTAATATGAGCAACAATAGACTCTTTAACTTTGCCGTTAATTTCGCATCCATTGAATTGTTCACTTAACGACGTTTAATCGCTGGCTGGCTATCTATGTAAATGTCCTCTCTGTGTCCTGTTATCCAGGGGCTCATGGGGACCCTCAGAGATCTT[C/T]AATTCGCACTTCAGCTGAAGATTGAGGAGTTACGGCAGAGAGATGCTCTTATCGACGAGCTGGAGCTGGAGCTGGACGCTAAAGATGATCTGATCCGCCGCCTGCAGGGGGAGCTCGACCGGCTACGGCTCTCCTCCGCTCCTGGAGTCTCCACAGCCACTGCTGGTATGGATCAAGGTGTTTCATTGCTCATTTTTTAGGTCACAAAAAGGTTTTGACTGGTAATATAAACTGAAAAAAATAATTATTAAATTTGCTAAATGGTTTAAGGTACAGTTGAGGCCCTCCTTTTTTATTTTATTTCAGCTAAAATAAAAGCATTTTTTTAAATAACCATTTTAAGGTCAATTTTATTCACCCCCTTAAGCAATGCAATAATTTTTGATTGCAGAACAAACCATTGTTATAAAATAATTTGGCTAATCATACTAACTTGCGGAGTTAGTTACCCTATTTAAGCCTTTAAATGTCACTTTAAGCTGAAATTAGTGTCTTGGAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31686
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000098135 Nonsense 64 481 2 13
Genomic Location (Zv9):
Chromosome 8 (position 53199713)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 50942441
GRCz11 8 50931463
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAAAACATCTCATTATTCCTCCTAACTGTCAATTCATTTGCATTTAGGT[C/T]AACAGCGCGCTTCTTCCCTGAGAGCGAGGCGGAAAACTCTGGTAACAGAA
Long Flanking Sequence:
GGCACTTAAGCTCATAACAGCAGCTCTGTGTCTCTTAAATAATTTTCATTAATTCACCATTCGTAAACAATAGAATTTTTTATTTTAAGAGTTTTAAGGTATTTGCAATCGAATAAAGAATCGAAACGAGAACTTGCAGTTCAAATCAAATTGGGACGTCTAAATCAATATCCAGCCGTATAGTGACTCCTCTGAGAGTCAAACTCTGGACACTGAATTTTTAAAGAATTTAAAGATTATGTTAACTGAGTTTTAAATCAGTTGCAAACTTTACAAAACTGCAACCCACAGATTCCCAATCGACACAAAGTCAAGGATGAAAGAAGAATGCTTTTATACAAACACAGTAGCACATGAAAAACTAACAAATCTGCATTATTTATATGCATCACACATCAGCGAACTGCCCAGAGTTCAGAGGTAGCAACCCAATGTTTTTAATCTTATAAAGAAAAACATCTCATTATTCCTCCTAACTGTCAATTCATTTGCATTTAGGT[C/T]AACAGCGCGCTTCTTCCCTGAGAGCGAGGCGGAAAACTCTGGTAACAGAACCAGTTACAGTGGAGCCAAAACTCGTCCTACAAAACCAGCCAATCAGCCACAGCAAGAGTCAAGAGTAAGAACTCTTCAGAATCATTTGTTTTTTTTTGTCACCTGCTGCTGCATTTCCCCAGTGTAACGCTTCATCTCTGTTTGTTTCAGGTCACAGAGACTGATAGAATCAGCTTTAGCAGAAAATGAGTGCATGAAATATCTGGACCGGGACCAGCTGCAGTGTTTGGTAGATTCTGCCTATCCCACCATGCTCAAACAGGGTGTGTGTCTCTTCCAGGAAGGGGAACATGGAGCCCAGGCTTACATAGTCGAAGGTGAGGGTGTGAATTTTACAATGATAAGAGGGGGTGGGGGGTGGGGGGGTACCTACTTTGGCGGTACATATGTTTTACGCAGCGAATGCCCCTTCCAGCTGCAACCCAGTACTGGGAAACACTCATACACTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa25410
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000098135 Nonsense 119 481 3 13
Genomic Location (Zv9):
Chromosome 8 (position 53199460)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 50942188
GRCz11 8 50931210
KASP Assay ID:
554-7427.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCACAGAGACTGATAGAATCAGCTTTAGCAGAAAATGAGTGCATGAAATA[T/A]CTGGACCGGGACCAGCTGCAGTGTTTGGTAGATTCTGCCTATCCCACCAT
Long Flanking Sequence:
TAAATCAGTTGCAAACTTTACAAAACTGCAACCCACAGATTCCCAATCGACACAAAGTCAAGGATGAAAGAAGAATGCTTTTATACAAACACAGTAGCACATGAAAAACTAACAAATCTGCATTATTTATATGCATCACACATCAGCGAACTGCCCAGAGTTCAGAGGTAGCAACCCAATGTTTTTAATCTTATAAAGAAAAACATCTCATTATTCCTCCTAACTGTCAATTCATTTGCATTTAGGTCAACAGCGCGCTTCTTCCCTGAGAGCGAGGCGGAAAACTCTGGTAACAGAACCAGTTACAGTGGAGCCAAAACTCGTCCTACAAAACCAGCCAATCAGCCACAGCAAGAGTCAAGAGTAAGAACTCTTCAGAATCATTTGTTTTTTTTTGTCACCTGCTGCTGCATTTCCCCAGTGTAACGCTTCATCTCTGTTTGTTTCAGGTCACAGAGACTGATAGAATCAGCTTTAGCAGAAAATGAGTGCATGAAATA[T/A]CTGGACCGGGACCAGCTGCAGTGTTTGGTAGATTCTGCCTATCCCACCATGCTCAAACAGGGTGTGTGTCTCTTCCAGGAAGGGGAACATGGAGCCCAGGCTTACATAGTCGAAGGTGAGGGTGTGAATTTTACAATGATAAGAGGGGGTGGGGGGTGGGGGGGTACCTACTTTGGCGGTACATATGTTTTACGCAGCGAATGCCCCTTCCAGCTGCAACCCAGTACTGGGAAACACTCATACACTCTCACATTCAAACAGACAGACTCATACACAACGGACAATTTTTATCTTTGGACTGTGGGGGAAACTGCAGCACCCGGAGAAAACCTACGAAAACATGAAGAGAGCATGCAAACTCCACACAGAAATACTAACTGGCCCAGCAAGGACTCGAACCAATGACCTTCTTGCTTGTTATTTAAGTTGAAGATCAGAGAAAACTATTTCTCACTATCATAGGGCTGACCCCCCATACATCTTGTTTTGATGTTCCTCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1566
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000098135 Nonsense 139 481 3 13
Genomic Location (Zv9):
Chromosome 8 (position 53199402)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 50942130
GRCz11 8 50931152
KASP Assay ID:
554-1509.1 (used for ordering genotyping assays)
KASP Sequence:
GGGACCAGCTGCAGKGTTTGGTAGATTCTGCCTATCCCACCAWGCTCAAA[C/T]AGGGTGTGTGTCTCTTCCAGGAAGGGGAACATGGAGCCCAGGCTTACATA
Long Flanking Sequence:
CAAGGATGAAAGAAGAATGCTTTTATACAAACACAGTAGCACATGAAAAACTAACAAATCTGCATTATTTATATGCATCACACATCAGCGAACTGCCCAGAGTTCAGAGGTAGCAACCCAATGTTTTTAATCTTATAAAGAAAAACATCTCATTATTCCTCCTAACTGTCAATTCATTTGCATTTAGGTCAACAGCGCGCTTCTTCCCTGAGAGCGAGGCGGAAAACTCTGGTAACAGAACCAGTTACAGTGGAGCCAAAACTCGTCCTACAAAACCAGCCAATCAGCCACAGCAAGAGTCAAGAGTAAGAACTCTTCAGAATCATTTGTTTTTTTTTGTCACCTGCTGCTGCATTTCCCCAGTGTAACGCTTCATCTCTGTTTGTTTCAGGTCACAGAGACTGATAGAATCAGCTTTAGCAGAAAATGAGTGCATGAAATATCTGGACCGGGACCAGCTGCAGTGTTTGGTAGATTCTGCCTATCCCACCATGCTCAAA[C/T]AGGGTGTGTGTCTCTTCCAGGAAGGGGAACATGGAGCCCAGGCTTACATAGTCGAAGGTGAGGGTGTGAATTTTACAATGATAAGAGGGGGTGGGGGGTGGGGGGGTACCTACTTTGGCGGTACATATGTTTTACGCAGCGAATGCCCCTTCCAGCTGCAACCCAGTACTGGGAAACACTCATACACTCTCACATTCAAACAGACAGACTCATACACAACGGACAATTTTTATCTTTGGACTGTGGGGGAAACTGCAGCACCCGGAGAAAACCTACGAAAACATGAAGAGAGCATGCAAACTCCACACAGAAATACTAACTGGCCCAGCAAGGACTCGAACCAATGACCTTCTTGCTTGTTATTTAAGTTGAAGATCAGAGAAAACTATTTCTCACTATCATAGGGCTGACCCCCCATACATCTTGTTTTGATGTTCCTCAGAGGGGAGCAAGTGTTATTTAGGGGGGGTCAGTCCACCCTAAACCCCCAACAATTCTCG
Associated Phenotype:
Not determined