Busch Lab

ZMP

myhz1.1

Ensembl ID:
ENSDARG00000067990
ZFIN ID:
ZDB-GENE-000322-5
Description:
myosin, heavy polypeptide 1.1, skeletal muscle [Source:RefSeq peptide;Acc:NP_001108561]
Human Orthologues:
MYH6, MYH7
Human Descriptions:
myosin, heavy chain 6, cardiac muscle, alpha [Source:HGNC Symbol;Acc:7576]
myosin, heavy chain 7, cardiac muscle, beta [Source:HGNC Symbol;Acc:7577]
Mouse Orthologues:
Myh6, Myh7
Mouse Descriptions:
myosin, heavy polypeptide 6, cardiac muscle, alpha Gene [Source:MGI Symbol;Acc:MGI:97255]
myosin, heavy polypeptide 7, cardiac muscle, beta Gene [Source:MGI Symbol;Acc:MGI:2155600]

Alleles

There are 2 alleles of this gene:

Allele Name Consequence Status Availability
sa40478 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa33640 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa40478
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000098060 Essential Splice Site 1550 1937 31 39
ENSDART00000098072 Essential Splice Site 65 451 31 40
ENSDART00000109263 Essential Splice Site 1551 1938 31 40
ENSDART00000123003 Essential Splice Site 1550 1937 33 41
ENSDART00000129660 None None 931 None 23
Genomic Location (Zv9):
Chromosome 5 (position 33938308)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 31700540
GRCz11 5 32300693
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGTGGAGACTGAGAAGGCAGAGATTCAGACTGCCCTGGAGGAGGCTGAA[G/A]TGAGTATCCGGAGATGGAGATTTATATGGGGTTATCTCTAAAACATTTTA
Long Flanking Sequence:
AAAAGCAGAGGAACTTTGACAAGGTTAAATTTAGAGTCATGTTGTGATGTGATGTTCTATTTCAGAAAGTAGTATTAGCTTTCTTCTGGAGAATACAAGTTGAACAAACCTGATATATTCCACCCTAAAGGTCCTGGCAGAATGGAAGCAGAAATATGAGGAAGGTCAGGCAGAGCTGGAAGGTGCCCAGAAAGAAGCTCGTTCACTCAGCACTGAGCTGTTCAAGATGAAGAACTCCTATGAGGAGACTCTGGATCAGCTGGAGACCCTCAAGAGAGAGAACAAGAATCTGCAGCGTAAGAATCGAACAGTTAAAATAAAAAATCTGATGAATGAATGTTCTTTGTGATACAAATTTTATTTTTCATTCTACAGAGGAGATTTCAGATCTGACAGAACAGTTAGGTGAGACTGGTAAGAGCATCCATGAGCTGGAGAAGTCCAAGAAGGCAGTGGAGACTGAGAAGGCAGAGATTCAGACTGCCCTGGAGGAGGCTGAA[G/A]TGAGTATCCGGAGATGGAGATTTATATGGGGTTATCTCTAAAACATTTTATACTATAAATTATTTATCTTTGTCATAGGGCACTCTGGAGCATGAGGAGTCCAAGATTCTTCGTGTCCAGCTTGAGCTAAACCAGGTCAAGAGTGAGATCGACAGGAAGCTTGCAGAAAAGGATGAGGAGATCGAGCAGATCAAGAGGAACAGTCAGAGAATTACTGATTCCATGCAGAGCACTCTGGACTCTGAGGTCAGGAGCAGGAATGATGCTCTGAGAATCAAGAAGAAGATGGAGGGAGATCTTAATGAGATGGAGATTCAGCTGAGCCATGCCAATCGCCAGGCTGCTGAGGCCCAGAAACAGCTCAGAAATGTTCAGGCACAACTCAAGGTATGTCTTTCTCTTTAGGTGCATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATTTCTTCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33640
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000098060 Nonsense 1900 1937 38 39
ENSDART00000098072 Nonsense 414 451 39 40
ENSDART00000109263 Nonsense 1901 1938 39 40
ENSDART00000123003 Nonsense 1900 1937 40 41
ENSDART00000129660 None None 931 None 23
Genomic Location (Zv9):
Chromosome 5 (position 33936539)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 31698771
GRCz11 5 32298924
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATGTGACTTTGCAGGAGGAACAAGCCAACTCTCACCTGTCCAAGTTGAGG[A/T]AGGTGCAGCATGAGCTGGAGGAGGCTGAGGAGCGCGCTGACATTGCCGAG
Long Flanking Sequence:
TCATGTTAAAAGTAAATCAGGTTGGAACACTCAGAAATAGTCATAGTCAAAACTTATTTAAGAAAATAGTTTAATAATGTGTTTTATTTAGGTTCGTGAGCTTGAGAGTGAAGTTGAGGCAGAGCAGAGACGTGGAGCTGATGCTGTTAAAGGCGTCCGCAAATATGAGAGGAGAGTCAAGGAGCTCACCTACCAGGTAAAGACATCCAAGAAAAAGTTTAGATCATGTAAACATAAAATTAAAGTTTGTTAAAATGGATCATATTAATCTGTTCACTATATACAGACTGAGGAGGACAAGAAGAACGTCAACAGGCTGCAGGATCTGGTTGATAAGCTTCAGCTGAAGGTCAAGGCTTACAAGAGACAGTCTGAAGAAGCTGTGAGTTCCTCATTTGAGAACTTAAACACCTGTGAACTTCCAAGATGTTCTTTTACTGATGCAGTTGTATGTGACTTTGCAGGAGGAACAAGCCAACTCTCACCTGTCCAAGTTGAGG[A/T]AGGTGCAGCATGAGCTGGAGGAGGCTGAGGAGCGCGCTGACATTGCCGAGTCCCAGGTCAACAAGCTCAGAGCCAAGAGCCGTGACAGTGGAAAGGTAATTGGTTATTTTTGATTCATGTGTTTTTAGACTTAACACAGTTTGGAACAATCACGTCATATATTTTGTTTTATACTGATCATGTGTTTGTTTACTCCTTTTATTCAAGGGCAAAGATGCAGCTGAGTGAACAAAGCTGAAGGAACCTGCTTCAGCACACCTCTAAACCTGTGAAATGAATAAACCTGGACTAAAATCAGCAGCTTTTATTGTATTTCATTTTCTCCATTTTATTGGTTCATTCACTAGTTGTTGTGGTTTTACCCTTACATATTTCATGATAAACTAGAACACTTGATAGGTATGTGACTTAAGAAGCAGTTTATGAAATAGGTTCAATAAACAGAACTTTGGTGTAATATTAGATTTTATATTCCTCATTATCATTTTGACAAAAGGAAA
Associated Phenotype:
Not determined