Busch Lab

ZMP

nrxn1b

Ensembl ID:
ENSDARG00000063635
ZFIN IDs:
ZDB-GENE-070206-3, ZDB-GENE-070206-3
Description:
neurexin-1-beta [Source:RefSeq peptide;Acc:NP_001073428]
Human Orthologue:
NRXN1
Human Description:
neurexin 1 [Source:HGNC Symbol;Acc:8008]
Mouse Orthologue:
Nrxn1
Mouse Description:
neurexin I Gene [Source:MGI Symbol;Acc:MGI:1096391]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa35390 Nonsense Mutation detected in F1 DNA Not yet available
sa35391 Nonsense Mutation detected in F1 DNA Not yet available
sa42109 Nonsense Mutation detected in F1 DNA Not yet available
sa18533 Nonsense Available for shipment Available now
sa42110 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa42111 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa22192 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa35390
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000093098 Nonsense 23 1470 1 20
ENSDART00000093166 None None 448 None 7
Genomic Location (Zv9):
Chromosome 13 (position 605420)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 603403
GRCz11 13 733694
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGGGTGCTCATCTGCTTTTTATCGGACTAATTGTATGTAAAGCGAACGCT[G/T]GATCTAGTCTCAGGTTTACAGGATCCGACGAACAATGGGTTGCGTTTCCG
Long Flanking Sequence:
GTCATACTCTGATTTGTAATTGATAACACATTAAAATCATAGTCATAATCTGATTACAAGTCATAATCATTTTATTCGATGTAGTTAATATAGTTTAAGCTAAGAATAACTTAGTAACTGTAATAAATCTGGGTTTTTTATTAATTTACTAAGGAAAATTGATTGTAAAGTGTTAACTATTGTACTTTATCCATTTAATTTAGTTAAACGCTCTTTTTTTATATACAGTAAAGCAATACACTAGGTATTGTTTCGTTATTATACCTTTTAAAATAACCTTTTTTGCAGTTTAGCCCAATATTGTGATGATACCGTCTACCAATCTGCAATTAATTGCAACAATAACATCTGGTGCCACCTTAAACCTACTTTGGCATGCATAATTTGGAGATTTCCTATAGATTATTATTATTATAAACATGCCAAACATCTTCATGATGATTCTTCACTTGGGTGCTCATCTGCTTTTTATCGGACTAATTGTATGTAAAGCGAACGCT[G/T]GATCTAGTCTCAGGTTTACAGGATCCGACGAACAATGGGTTGCGTTTCCGATGTGGAACGCTTGCTGCGAGAGCGAAATGAGCTTCAGTGTGAAAACCACACATCTGAATGGCCTCCTGGTGTACTTTGATGACGAAGGCTTCTGCGATTTCCTCGAGCTGCACGTGCACGTTGGGAAACTCAGATTGTGCTTTTCTATTTTCTGTGCCGAGTCCACATGCGTGCTTTCTGACGTCGCCATCAATGACAACCGATGGCATTCGGTCTCGATTATGAGGAACTTCAGAAACACCACACTCATCGTGGACGACGAGGTAAAGTGGGAGGAGGTTAAATCCCAAAGGCGAGACATGACGGTTTTCAGCCACTTATTTTTAGGAGGGATTCCCTCAGAGCTGAGGTCGGTGTCTTTACAGCTGACGTCCAAGACTGTGAAAGATCACACTTCGTTTACGGGCTGGATAATGGATGTGAAAGTCAACGATTCTGAGCCTGCGATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35391
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000093098 Nonsense 405 1470 5 20
ENSDART00000093166 None None 448 None 7
Genomic Location (Zv9):
Chromosome 13 (position 616792)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 614775
GRCz11 13 745066
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCACAGCCGACCTGCCCGAATCTCCTGTCAGCAACAACTTCATGGGCTG[T/A]CTGAGGGAGGTAAAGAAACTGCCACACCAAATCAGTGCAGGCTGTGTAGA
Long Flanking Sequence:
ATGGATTTGAGATGAAATGAACAAGATGTCCTGTCCAACTTCATCCTGTCACATGTAATTTGCATATATTGTCGTTTATCAGATGTCTATATGGGGACTCAAGTAATAAACAGAAGAGTGGGAGCCGCTCTAATATGGAAAAGTTTATTCCATTATTTTGGCGGTGGCACTGCAAAGTCATGATCACCTTCAGCCAATAGACTGGCATGATTCTGTAGGGCTTCAGATCTGATGTGCTTTCCATTGCATCATCATTATGCAGCATTCATATGAAAGAGACTGAAGGATCAGGAGTTCAGAAAGTATCCAGCTGCTCTCCTCCTCCTCCTCCTGTGGTTTGTTTTGCAGGTTACGATATCTGTGGACGGAATACTGACCACCACAGGATACACTCAGGAGGAGTACACCATGCTCGGCTCTGATGACTTTCTGTATGTCGGAGGGAGTCCCAGCACAGCCGACCTGCCCGAATCTCCTGTCAGCAACAACTTCATGGGCTG[T/A]CTGAGGGAGGTAAAGAAACTGCCACACCAAATCAGTGCAGGCTGTGTAGAGCTTAGAGTCACAATCGAATCACAATGAAGTGTGCTCATATTTGTAGATAGTTGTGTTTGTTATATGCAGTATATCTGTCACGTCATTATTTAGCAAAAATTAATATGCCCTCTACCTTTCATTTTTGTTAAAATTAAATACATTTTTATCTACCTTTAGGGTGGACCTATGAGTCTCTTGGGGCGGGGCTATCACTCATTTGAGGCAGAGCTACAAGTCAATTAGGGCGGAGCTAACTGTCATTTAGGATGTGGATCTTTGGGCAGGGCTACCAGTCATTTAGGGTGTGGCTATAAGTCATTTAGGGTGGGACTATCTGTGTTTTAGGGCAGGGCTGTCAGTCATTTAGGGTGTGGTTATCAGTCTTGTGGCAGGACTATTAGTGTTTAAGAAGGAGGCTATCGTTCATTTTGGGCAGGGCTATCAGTTATTTAGGGCATGGTTATCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42109
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000093098 Nonsense 562 1470 7 20
ENSDART00000093166 None None 448 None 7
Genomic Location (Zv9):
Chromosome 13 (position 622569)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 620552
GRCz11 13 750843
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCGTATTCTTCAGTGTTCTCTCTGAACCGCAGGCACCATCTCCATCAACT[C/A]AGTGCGCACCCCGTACCTGTGCCCCGGAGACAGCGAGCTCCTGGATCTGG
Long Flanking Sequence:
GTGTTCGTTGCCCTTGTCTGCTTGGTCCCTCACAGTATCCAATAAATTGTTACGATTTTTGACATGGAAGAAAAACCTCTCCTGACCTTTTTTTCTTGAACACGAATGAGATTGATTTAATATTCCAACAATATACATTTATGAATGGATTATGTCAAAGTGTTTCTAATGCGGCGGGCGTTTATAGGGCTGAGAGTAAATCTGACATTAGTCAAGGAGAAAAACTCCACAATGGTGTTATCAAGCCTTTCAGAAAGAGGAAAATAACAGTGTAAGAGTGATGTCATTTCAAAACGAAAATCTCGATTATTTCTTTTGCCCCAGTGTCAGATTATTTTGCTTGTTTTAAGCAAAAACTCACTTAATTTTAATGCATTATTTCTAATACCAAAATTATAGTTTTAATTTGTCCAGAAAACACTTCTTGATTTAAGAGTGTTCGAATATTAAGCGTATTCTTCAGTGTTCTCTCTGAACCGCAGGCACCATCTCCATCAACT[C/A]AGTGCGCACCCCGTACCTGTGCCCCGGAGACAGCGAGCTCCTGGATCTGGATGATCCCCTGTACCTGGGCGGCGTTCCGGAGAGCTCCAGTGGGACGGTGTTCCCCACTGGGGCCTGGAGCGCCCTGCTGAACTACGGGTACGTGGGCTGTGTGCGGGATCTGTTCATCGACGGGCGCAGTGTGGATGTCCGGCGCGCAGCAGAGCTGCAGAGAGCTGCAGGAGTGAAGCCGTCCTGCGGTAAAGAGCCGCCCGGGAAGTGTGTGAGCGAGCCCTGCCTGAACAGAGGAGTCTGCAGGGAGGGATGGAGCCGATATATCTGCGACTGCACCGGGACGGGATTCCTGGGACACTCCTGCGAGAGAGGTGTGTGTGTATGAGTGCGAGAGTGTGTTTGATAATGATAATGATGCGGATCTTTCCGTCTGCAGACGCCACCATCCTCTCTTTCGATGGCAGCAAGTTCCTGAAGGTGCAGTTTTCTGCAGCGATGCACACCGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18533
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000093098 Nonsense 897 1470 11 20
ENSDART00000093166 None None 448 None 7
Genomic Location (Zv9):
Chromosome 13 (position 632135)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 630118
GRCz11 13 760409
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGCTCCAGCTACGTGACGCTRCCGTCTTTACAGGCGTATTACTACATGTA[C/A]CTGTTTTTCCAGTTCAAGACCACCTCCGCAGACGGACTCAYACTCTAYAA
Long Flanking Sequence:
TACATGTCACTTTAAGCTGAACACTAGTGTCTTGAAGAATATCTAGTCTAATATTATGTGCTGTCATCATGGAGAAGAGGAAACACATCAGCTATTAGAGATGAGTTATTAACACTATTATGATTAGAAATGCGCTGAAGAAATCTGCTCTCTGTTAAACAGAAATTAATAATTCGGGAGGGCTAATAATTCTGACTTTTATACATAAAAACAGGAGAGATACCAGGCGACCACACGCAGCTAGAGTTTCACAACATCGAGACCGGCATCATTACAGGAAAACGCCAGTTACCCACAATGCCCTCCAACTTTATTGGACATCTCCAGAGCCTGATGTTTAATGGTAAGCCGTACATCGACCTGTGCAAGAACGGAGACATCGATTACTGCCAAACCAACGCTCCAATCGGCTTTAAGAGCATCATCGCAGATCCGGTGACGTTCAAGTCCTGCTCCAGCTACGTGACGCTGCCGTCTTTACAGGCGTATTACTACATGTA[C/A]CTGTTTTTCCAGTTCAAGACCACCTCCGCAGACGGACTCATACTCTATAATAGTGGAGATGGCAATGATTTTATCGCTGTAGAGCTGGTGAAAGGGTAAGTTATGGACAACACGGGCTCAATGGGAAAATGTGCTACTGCAAAACATTTGTTTCTAGGGTAGGGTTGCAAATAAAACACTTCAAAATCAATGATTACAGGCACAACGTTAAATATCGCTAAATAAAATGCGACATGTAAGCATTGCACTTTCAAGATGGCAACTTTCTCACAATGAACCAGAAGCTTTTATTAATCTTAGCTGTTAAAATAAAAGTTGTAAACATTTTCTGAAACAAAAATAGTAAATAATGAAATTCTGTTGCATTTTTTAGCTAATATTAAAGTAGTAGCTGTAATAAATGTGGTTATTTCACACTGTTGATTTGAATTAAATGCTTTTTAGCAGCTTCGGTTAATATGATAATATCGTATACTGTATTTTCTATACCATTTATTAAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42110
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000093098 Essential Splice Site 1050 1470 13 20
ENSDART00000093166 None None 448 None 7
Genomic Location (Zv9):
Chromosome 13 (position 634076)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 632059
GRCz11 13 762350
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GATGACCGAAGCGCTGGTCTGTGTCGGGCAGATCGAGAGAGGATGTGAAG[G/T]TAATAAACGTTTTTTTAAAAACATTTTACGGTCAGTATTTGTTTTAGATT
Long Flanking Sequence:
CTTCCCTCTTTGGGATGGAACCACGAGGCGACGTTCATTCACAGAACGCAAGTTTCTGGAGGACACATACATCTGCAGAAGTGAGAGCAGATAAGGAGCAGCAAAGCCAGAAGTGGCTTTGTAAGCAAACATCAGAGCTTTGAATTTGATGCGAGCAGCAACTGGCAGCCAGTGCAAACGGATGAGCAGCGGAGTGACATGTGCTCTTTTAGCTTCATTCAAGAGGTTCATTATTAAGGCTAAACTGCTTTTATTAAGAAACTGTTGTTGCTTGTCAACTATAATCCAACTTCTTCTAATCCCGTATTCTCTGGCTGTGTTTGCAGGTGATTTGTTTGTGGGTGGTGTTCCAGAGCAGATGTATAAAGATCTGCCCAAGTTAGTTCATGCAAAAGAAGGGTTTCAGGGCTGTCTGGCGTCTGTGGATCTGAACGGGCGTTTGCCAGACCTGATGACCGAAGCGCTGGTCTGTGTCGGGCAGATCGAGAGAGGATGTGAAG[G/T]TAATAAACGTTTTTTTAAAAACATTTTACGGTCAGTATTTGTTTTAGATTAGAAATTGGGGAAAATATATACGTATTATAAGCCGATATCGCAGTAAGGGTAATCAATGACACATGAGTCTGCTGTGAATCCTTTCCTCATCTCTATTTTGCAACCCAGGCTCATTTTGAAAACGTAGTCCAGCGGACGTTTCTGGAGACCGCGAAAAATGTCCTGGGAGGTACGTATTTGTGCAGTTTTTGTTTTCGCGAATCCGCGAGAGGCCGCTGTGCGCGCTTTTTCGTATCCCAAACGTCTCTCGCGAGTGCCGTTTGCACCCGTGCTGTTCTCGCGTCAACCCACCAGAGGCCGCTGTCTGACTGACCGAATGATTGACTGCGCGACCGGCCAATCGGCTGACCCACCCTCCTCCTTCCCTGAACCCAACCAGTTTTACCGATTGACCCGCCCGCCCGCTCACTTCCCTAAACCCGAGCAACAATTTAGAAAAACCGTCTAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42111
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000093098 Essential Splice Site 1235 1470 17 20
ENSDART00000093166 Essential Splice Site 213 448 4 7
Genomic Location (Zv9):
Chromosome 13 (position 669411)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 667394
GRCz11 13 797685
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGTAGACTTCCATATCGGCGGCTAGTTGAAGAATCGCTACCGAAGAACGG[T/C]AAAAACCAGGATAAAGCTTAAGTAATACTATTTTAACAGTTTTAACAGTA
Long Flanking Sequence:
AAATCAGTGCATAGCGAGACCGAGCATTTACAGTGACCAAACACAAACCAAAACGTTTAAAGAGGTGCAGAACTCTTTCTTACTATTCTTTCTGTTTATTAAATTGACATGCTTATAAAGCAATAGTGCAAAATAAATATGTCTTACTGCAAATAGTGTTTGGACAACAGTTGCAGGATGACACTGTATATCTGTAACAAAATATAAAACATTCAAAGTATTTTAAACAGCCACTACAAATGTGCTAGGAGCCCTAGGAGGTTAATTCTGTATATATATAGTCATCTGTACACAGTCTATGCTGCTATAAACTAAATTAAGTGTAAAATATATGTAAATGTAAACATAAGAGCTTAAGTATTCAGTTTTTAACCTTTGACCTTGTAATTTAACCAATGAAATGTCTTTTTAAACTTTAAAGGACACATTGATAGTCACCGGCTGGGAACTGGTAGACTTCCATATCGGCGGCTAGTTGAAGAATCGCTACCGAAGAACGG[T/C]AAAAACCAGGATAAAGCTTAAGTAATACTATTTTAACAGTTTTAACAGTAGTATTTTTGCTTTAAAGCAATAATTTAATCATTAATTGATATTAAAGTAAGCTATTTAAATAGGGCACGCTTGGAATAATGTATTAATGATAACTAGTTTGTTTAAACACTCAGTTAAAGGGACTGTACATTTAAAATAATTTCAACTATATATAATGTAAAGATTTTTGATAAATTAATTAAGTGTAATGTAAAATTTTGATCTAATAACTGTAGCATGTGTCTGTGATGAATTAAGAACCTGGCACAGTAAATAGACCATATTTAATCATGTGATTTAGAAATAAAACAATAAATAGTATTTCAATATATATATTTTAAAGTAACAAGCTTGAGTCCCTTTAACAAGATTTTACATCAATAAAAATGAGATAAATGATAATAAGTTATTTAAATGCATGTCTGATTTGAGATTTTAATATGCAGTGTGCCTCCGCCGTCGCTGTTCTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22192
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000093098 Nonsense 1437 1470 20 20
ENSDART00000093166 Nonsense 415 448 7 7
Genomic Location (Zv9):
Chromosome 13 (position 679900)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 677883
GRCz11 13 808174
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TACCGCAACCGAGACGAGGGGTCGTACCATGTGGACGAGAGCAGAAACTA[C/A]ATCTGCAACTCCAACGGAGCCGCGCTGAAGGAGAAAAACACTGCAGACGA
Long Flanking Sequence:
AAAGTGATTGACAGGTGGTGATTATGTGTGTGTCTTGCCTTTATTCATTTACTGTATGATTTGTTTATGGGTAAAACAAAGACCATGCAGGTCAGGTAGTTTAAACGGTAGGCTACAAATAATTAATTGGTCATTAATTAATGAATTATTCATAATCGAAAATCGAATCGAATCGTGCCTTTAGAATCGAAAATGTAATCGAATCGAGGATTTGGAGGATCGTGACACCCTTAATATCTACTGTGAAAGCGCTATACTAGTTAACTTGAATTGACTAAAGGGACCCTGTGTTGTTTTGTTCCTCCAGCGGGCCCCACAGGCCCCGCGATCAGCAGTTTTCCAGGCCCGGCGGAGGTTTTCCGGGAGTCCAACGGCACCACAGGGATGGTGGTGGGCATCGTGGCGGGCGCGGCGCTCTGCATCCTCATCCTGCTCTACGCCATGTACAAATACCGCAACCGAGACGAGGGGTCGTACCATGTGGACGAGAGCAGAAACTA[C/A]ATCTGCAACTCCAACGGAGCCGCGCTGAAGGAGAAAAACACTGCAGACGACGACAGCGGGAGCAAGAGCAAGAAGAACAAAAACAAGGAGTATTACGTGTGATCCAATAATCCTGCAAACACTCAGAGTTTGTGTCTTGTTTCTAGAGCAGATATCTAAAACCTCTTTAATCAAGAAGTATCTTCTAGATGAGCACTAAATGTAGTGTTGTTCTCAGAAATAATGAGTCAAAATGAAGGGAGTTTCTCATTAAAACAAGCAGAATAATCTGACACTGGGGGAAGCAGAATTCACGACACACTGAGGACTGAACACAGGAGGTCAGTATATACACAATGTTTTATCAACAAAGTTAATAATGAAGCTTAACTGAGTTTGTGGAGATTAAGGACACACGACACATAAACATGAGTCCAGGAAGACGAGGAACACAGGGACGCTAGAACAGGAGAAAAGCTGGAGAGGGATTGGATGAAACTCAATGGCTGTTTCTCAATTCT
Associated Phenotype:
Not determined