Busch Lab

ZMP

zgc:153368

Ensembl ID:
ENSDARG00000062987
ZFIN ID:
ZDB-GENE-060929-688
Description:
tRNA wybutosine-synthesizing protein 1 homolog [Source:UniProtKB/Swiss-Prot;Acc:Q08C92]
Human Orthologue:
TYW1
Human Description:
tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:25598]
Mouse Orthologue:
Tyw1
Mouse Description:
tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) Gene [Source:MGI Symbol;Acc:MGI:2141161]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa35843 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa14926 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa35843
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091640 Essential Splice Site 2 730 1 16
ENSDART00000142870 Essential Splice Site 26 754 1 16
Genomic Location (Zv9):
Chromosome 15 (position 15891439)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 16936402
GRCz11 15 16872424
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATCGGTGTTGTCGGGTTTGGTGTGTTCTGCAGTCGGCGCTGAGATGTCAG[G/A]TAACGTTAGGTTTTTATTTTGCTAAGCGTGGCTGATAACAGCATACAATA
Long Flanking Sequence:
CACCAAATATATTATTCTGAAAACCTATGCAAGCAGGTAAAACGATCAGAGAACTATTAATAACCACGCGAGTATCTTTGTTTGACGCAGAACTGAGAGGAGTTCTAAAGGTTTGTGTTGTCAAAAATAAACGAATCTAAAGAACCTTTGGGGCCATGTTTGACTAAAGGTACAACCTTCTCGCCTTCTTCGCACCGACATTAATTATTTTTATGAATAAGAATTCAAGCAGAGAACACTCGAAGACTCACGTGGAGCTTAATGACCTGAGATGACCTAATTTCCCAGAATTCCTGTCATAACAATATGGCGGCGTCCTGCGACATGCAGCCGTAAAGTTAGCCCGTTATTTATATCTGAGACGTATGAAGTTAAATCTTTGTCTGGTTATTGTAAAACATTTATTTACTAGACTGTGTTGATGGAGAGAGTACATGAGATGCTGTTTTTATCGGTGTTGTCGGGTTTGGTGTGTTCTGCAGTCGGCGCTGAGATGTCAG[G/A]TAACGTTAGGTTTTTATTTTGCTAAGCGTGGCTGATAACAGCATACAATATATTACATTAAATAACTTATCATAGCAGACAGCGTTGTTATGCTCAAAATTGTGTCCACGAGCACATTTTGCTGCATTATAATAATCCTGCGGTCGGGCTCTGTCTCAAAATCTAACTTACTTGGCTCCCTACCTAGACTGCATTTTTGGACAACACACGCACATTCCGAGTTTCAGGTTTTACGAAAACGCGGCAATAATGATTGACACGCCGGTTTTATATTCGTACATTCCAGTAACAACTTGTGACACGCTCACTATATTAGTTGCTATGGTACGTTACTTTAAATATTCGTTCAGAAATAGCATGAAGTATAACTTCAAAACAACATTTGCACTATTTATTTGACTGTGAACATGTTGTAGCCTACGCTGATAGTCATAATATGATTTTACTGTGTCGAATTTGCCAAGAATACTTCTGTGAAATAATAAGTCAGAGATAATGAG
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa4598
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091640 Essential Splice Site 460 730 11 16
ENSDART00000142870 Essential Splice Site 484 754 11 16
Genomic Location (Zv9):
Chromosome 15 (position 15837676)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 16882639
GRCz11 15 16818661
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATTCAAGAGGCCATGGAGAACCACAGGAACATGATTCGCCAGTTCAGAGG[T/A]AAGAGGGTCACTGTCCATTACCTTCAAATCACCTCTCCTGAAGTCAAAAT
Long Flanking Sequence:
TTTTTGAAACCTGTTTCTAATTAAAACTATTTAAAACAATTTCTTTTTTTTTTTTTTTACAACTATTTACTACTATTTTATCTTGCAACTAAAAACTAGTGTCCTAGTTGTTTAGGAGACACATTGGCAAATCTATATTGAAAATGTAGTTTGTGCACATCCTCGTCTGTACCCTTAGAGGAATAGAGTGGTATGACATCACATCCAGCGTTTTCTCATCTCCAGTTGCTATTTATGGCAGGGGACGGAAGTAAAACCACACTGACTGGCATTTGTGCCCTTTGCTGTGATGTGAGAGCTGTTGAAAGGGTTGCGGGATGCTAATGTGTGTCCGGTGGGGTGCAGGTGTTGTTCTGACAGGAACTGTCCTTTCTCATTCTCATTCACAGACACCACACCAACCCAGTGGGCACTGAGTGGCGCTGGAAAATGGACCCAGCTGAGAAGATTATTCAAGAGGCCATGGAGAACCACAGGAACATGATTCGCCAGTTCAGAGG[T/A]AAGAGGGTCACTGTCCATTACCTTCAAATCACCTCTCCTGAAGTCAAAATTAAACTTTGGTAACACTTTATTTAGATGGTCTATTTGAGTATTGAGTATATTGAGTATATTTGTGTAGACTGTCTGCTCAATATCTGTTGATACTGCTCCTTCAACAGACATTTAACTGACTATAAGAAACTTGACATGAAATAAGTACATGTCAACTTAAATTAGATTATAAAGAGACTGTTAGGTTGGGGTTAGTGTAAGTTAAATTCAACAAACAGACCATCAAAATAAAATGTGACCTAAACTTTTATTGAAAATGTGTATTCAATATGTTAGTTTTAAGGTTACCTATTGACCTTATTATTCACATACATGTGGACACAGCCATTGAAATTTGGCTCAGGATATTTGTCTTCCATTGGTTTTTAAACATTAGAAAGAGCTCACTATGCTGCTTGACTGTTACAGTCACACCCATAACACAATTAAGAGAAAACATAAATGGATCA
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa28423
Status:
Less stringent filtering
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091640 Essential Splice Site 519 730 12 16
ENSDART00000142870 Essential Splice Site 543 754 12 16
Genomic Location (Zv9):
Chromosome 15 (position 15816942)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 16861905
GRCz11 15 16797927
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACATATCCAGCTTTTTGGTCACCAACGCCCAATTTCCTGAAGAGATCAGG[T/A]GAGATTTTAAAACTTCTGGTGCATTGGTGTATTAAATGCTGAAAAAAAAG
Long Flanking Sequence:
AATAGAAAGTTTTAGTCAAAATGGTAAGTAACATTTTTGCCACATTACACTCATTTGGCGCTTGACAAGTAAAAATGTTTGTCTCTGATTATACGAATAATCCTAATGCAATAACTGTTTTTTTTTTTTTTTTTTTTTTTTTTACATTTTCCCTCCAACAATTCATCACAGAATTGCATGGGAAATGCATATCAGTCTGACACTGATCTCTGTGGCTAGTGGCAGAGTAACCGAAACATTGCCCAGCTTAGCTTTAACAACTGCTCTCAGGTTGTGACCATTTTAAATTTTAACCAAACAGTATATTTGATCATGTAACAGGTGTTCCAGGTGTTCGTCCTGAGCGTTTTGAAGAGGGCCTCACCGTGAAGCACTGTGCTCTGTCTCTGGTGGGTGAACCGATTATGTATCCTGAGATCAACTCCTTCCTTAAACTACTCCACCAGCAGAACATATCCAGCTTTTTGGTCACCAACGCCCAATTTCCTGAAGAGATCAGG[T/A]GAGATTTTAAAACTTCTGGTGCATTGGTGTATTAAATGCTGAAAAAAAAGTCTCTTCAGTATCTTAAATAGTTATAGCCCTGGTTGTGGTTATTAAAATGGACATCTTGTCATGCATCATTTAGTAAATCTGATTTGGTGCCCACAGACAAGCCCCTTTTTAAATGTGTTTGTTCTCTGCATATCTGCATTAGTAACTACTGAACATCCTCCAGTTTGAAGTCTTTCCATAGTCTTTGAAGTCCCATTCGGGCTGTAACTGGACTGATAAGCCATAATCAGGCACTGAATTGCAAATCACAGCGTCTTCGGCTCCAAGCTCCTCCAATTCCAGCAGATTGTGCTGAAATTTATGAGTTTTCAGGAGAAGCCAAAAGCTTTTAGCGCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCCCTCCCTTGCTTAATGCAAAATACATCCTCTCCTCGTTCTCCTGACTCCTGCACGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14926
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091640 Nonsense 526 730 13 16
ENSDART00000142870 Nonsense 550 754 13 16
Genomic Location (Zv9):
Chromosome 15 (position 15813150)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 16858113
GRCz11 15 16794135
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTGTTTTTTNNNCAACTTTTTTTCTTTTTTATAGGAGTCTCGTGCCTGTTACT[C/T]AACTTTATGTCAGCGTTGATGCCAGCACCAAGGACAGTCTGAAGAAAATC
Long Flanking Sequence:
ACTACATCAGTGAGTTGTTGAGTTGTGATTGTTTGACATTTTTGCAACACAGTGCTTTCCTACAATTTAACCAGCATAAATTCTCTTTGAGATCTGATGTGTAAAGCTTCGAGTAACAAACATTTTTCTGATACAATTCGAGTCGAGCTGGTTCAGAAAGATTCATTTCACCATTACTACTGTTTTTATTAAAAGGGTGATAGGGTGATGTATAGGTGGACAGTCCAGAGCCGACAGTTGTTGGTACATTATCTTAACATTTCTTGCTCCTAGCTTGACTTCAGTTTTCACCTCACCAATTCAATCACTCAGTTGTTTTGGTTTGCTTTGTTTTATACAGTATACGCACAGCAAATAAAGAATGCTGCTCTATCTGGCTAAAATGATCTAGATCTTTACGCCTATGCACAGAAATATGTTTAAAACCTTCTTTACATATTGTTAATTTTACTGTTTTTTCAACTTTTTTTCTTTTTTATAGGAGTCTCGTGCCTGTTACT[C/T]AACTTTATGTCAGCGTTGATGCCAGCACCAAGGACAGTCTGAAGAAAATCGACCGTCCCCTCTTCAAAGACTTCTGGCAGCGCTTCTTGGACAGTCTCAGAGCTCTCGGTGAAAAGGTACATCCTTTGTGCTGTAGTTCAGATCAAACAAATGTCCTCTCCCACAATTATACATTACAAATTGGGGAAAAAAATTGTTGGACTTTTTAAGTAATAGGCATACAAAAAGGATAAATGTGTGCATATTTTAAAAGAATATTTGCAAAAAATTTTTTTTTTAAATGATTACTTCCTAACTACACTTAACTACAAATTTTTTCAATGTATAATCTGGAATATAAATCATATTTTTTCCCTTATTCCTCCTACATTACACATCATCTTTTAGTGTAGCTAAAAGTTTAAAGTTACGACAACTATACTGTATGCAAAGCTTGCACATTTAGGTTTGTGGTTAATAAAAGAGCAATTTAATATTGTTTTTGTATACTAGCTGTTTGT
Associated Phenotype:
Not determined