ZMP
mll4a
Ensembl ID:
ZFIN ID:
Description:
Novel protein similar to vertebrate myeloid/lymphoid or mixed-lineage leukemia (Trithorax homolog, D
Human Orthologue:
AD000671.3
Human Description:
Histone-lysine N-methyltransferase MLL4 [Source:UniProtKB/Swiss-Prot;Acc:Q9UMN6]
Mouse Orthologue:
Wbp7
Mouse Description:
WW domain binding protein 7 Gene [Source:MGI Symbol;Acc:MGI:109565]
Alleles
There are 10 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa30709 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa43228 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa23447 | Nonsense | Available for shipment | Available now |
| sa15376 | Nonsense | Available for shipment | Available now |
| sa36784 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa23448 | Essential Splice Site | Available for shipment | Available now |
Mutation Details
Allele Name:
sa30709
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000091588 | Nonsense | 269 | 2863 | 3 | 37 |
| ENSDART00000136957 | None | None | 1897 | None | 27 |
| ENSDART00000147922 | Nonsense | 277 | 801 | 3 | 7 |
Genomic Location (Zv9):
Chromosome 19 (position 9863238)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 19 | 9321777 |
| GRCz11 | 19 | 9240702 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGAGCCTCCAAACTTAAAGACACCCAAGGCCAAAGAGCTTCAGCAGACTA[T/A]ACCAAGAGGGTCAAGACAAAAGGAGTCACCGCTGGTGATGAGGCAGAGGA
Long Flanking Sequence:
GAATAATCGAATGCTTTAATACTTTTCATCCCTCTCTTTTATACAGACCGTGCCCTTAAATTGGCATCATCAAAGGTGAAGCGCTCCTCAGCAGCAGATTTAAAATCATCAATATTGAAAAAACCTGGCATGAGAGGCAGACCCTTTTCCAGAACTGACCAAAAATCTGTAAGGCCCAAAATGGTAGTTAAAGTGGCAGCCAAAAGGGTGACCAAAAGAGAAACAAAAAAGCCATCTGTAAATGGAGATGGACATTTAAAACAGGGCAGCTCAAGCAAGACAAATGGCAGGGTACTCAGGAACCAGAGAGAGGGAACAAGGGTCTCGTCACTGACGGAAAATGATAAAACTACAGTGGATGAGGATGATACCAATGTAAAGTCACAGACGCATGGTTCCAGTGCTGCGGAGAAATTAGTGTGGACTTTGACACTGGTTAAAGGTAAAGAGCGAGCCTCCAAACTTAAAGACACCCAAGGCCAAAGAGCTTCAGCAGACTA[T/A]ACCAAGAGGGTCAAGACAAAAGGAGTCACCGCTGGTGATGAGGCAGAGGAGGTTTCCGCAAAACCAATGGCCAAACAGAAAAGGGGCAGAAAATCTGCAGCAGACAAATTGGCTCTTAAATCTCCTGGCACAGATGTTGGAGCATCTTTAAGTGACAGAGTGTTAATTTCTTCCCAAAGGAAGCCTTTCGTAAGGCGACGAAAGCGCGGCCAGCGAAGGTTACTGCTAAAGAAAGTTCACCGCAAAGTACCTGACAGTCAGAGGCAGGCCTCTAGTATGCCTAGAAAGAGACAAAGACTTTCTGTCTCAGATACAGACCCTATAAATGTTCTACAGCCGGTGGAGGGACAAGAACAAGCACTCCTGGAGTCCACCTCTGGAGGCCAAGCTGAAGAGCTGAAACATCCCACCAAACCTACTGTAAGCGCTCGTTCTTCACGTGTCATCAAGATCCCAAAGAGGTTCATGGATGACGAGCGAATGTCTGCTCTTCCAGAAAG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa43228
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000091588 | Essential Splice Site | 605 | 2863 | 3 | 37 |
| ENSDART00000136957 | None | None | 1897 | None | 27 |
| ENSDART00000147922 | Essential Splice Site | 613 | 801 | 3 | 7 |
Genomic Location (Zv9):
Chromosome 19 (position 9864246)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 19 | 9322785 |
| GRCz11 | 19 | 9241710 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GATCAGACACCGCTTGCTTCTTTAGCGGAAGCCTCTTCTAAGGAGAATGG[T/A]AAGGTTTTTGCTGTCAAACTTGTAGAGCACTTTTATAGTAGAAATGCAGC
Long Flanking Sequence:
CTAAAGAAACCAGCTCTTACCGAGCTCCCGACAGATCTCAGCAAACCTAATACTGATCATCAAACGCTTGAATCTGGCAGCAGGCTGAAGACCACGCAAGAACTGGACATCGTAAATGACGATGAAAAAAGTGTTTTAGAAAAAATGCAATCTCAAGGAGTCAAACCTGCTCTGAGCTCTTCGAGGCTCTCTGGAGGAGCTCGAGGAAGAGGTGGGAGAATCGGCCAATCAGCAGACCACTATAAAATATACTGGAAGCTGAAGAAGCTCACGGCCTGCCTGGCCAAACGAAAGATGCAGCGGATGGCTGGTGATAGTTCCAGACTAACAGAGGAAGATGCTGAGGAAGGGACCCAGGGTACTCGAGAACAAAAGTCTGATCTGAAACTGCAGGACATCTATTCTCCGGGAGTGGTGCCAAAAGTAGCCATACGTGTTGGGGATCATTCAGATCAGACACCGCTTGCTTCTTTAGCGGAAGCCTCTTCTAAGGAGAATGG[T/A]AAGGTTTTTGCTGTCAAACTTGTAGAGCACTTTTATAGTAGAAATGCAGCTCTGAGTGCTTTGAAGTTAAAAAGAAAAATGTAGTTAACGTTACACCAAGTATTTCACATAAAATGTCATAGTTATTATAACACAAAATACAGTAAATGTTATTATATTCTATAGCATAGTTACTAGGGATGTAATGATTCACCGTGAGCCAGTTGACAATCGATTGAAATATGCGACAATAAAAACCAGTTCAAATCTTGAATCAATCGCAATACATGTTTTGAACAGAGGGGGCGCTGTTTAGAGATGCAAACTCGCTTTACCTGCACATCAGCAGCAAGTAGGTCTGTGTATTGGCAAGGGCCTCACGATATGATACATATCACGATACATGGGTCACGATTCAGTATATCACGATATATTACGATACAACAAATATTGTGATATATTGCAATAGTTTGTATTAGTATGTGTGTCATGTTATATAGACAACTTGATCAAGTCAGCAG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa23447
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000091588 | Nonsense | 629 | 2863 | 4 | 37 |
| ENSDART00000136957 | None | None | 1897 | None | 27 |
| ENSDART00000147922 | Nonsense | 637 | 801 | 4 | 7 |
Genomic Location (Zv9):
Chromosome 19 (position 9867092)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 19 | 9325631 |
| GRCz11 | 19 | 9244556 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACTCCACTGAAACAAGTGCACAAAATGAGCAGCAAGGTGGTATCCCGCAG[C/T]GAATGAGTGTTTCCGGAGCCAATAGGAGGATGATCCACTTGTTGAAGAGA
Long Flanking Sequence:
TAATCTATATGCCTCTAAACATACTTTGCACAAGAATGATGTCTTAGTTTTCAAAGACATTCCTTTTTTTTTTATGTTTACATGAACACAACAATGGCGGCATTTTCAAAAATGTCTATACATGTTTATAAATTTATGCATATTCAGTCCAAAAATGACGTCATGTTGTAAACGAACCGGCAAAACGTATAAATAATTTACCATATTTGGCTGGAAAAAATGTTGTGTACACGCCCTCTTAATCTAGTCATTTTAAGAATACAACACTTTATTGTTGGCTTATGTTTATTAAAACTATTAGCAGATACTGTACTAACTGTTAAAATATTCATATATTAAATAACAACATCAAATTATTTCCTAAGTATGTCTTCTTTCCAAATGTGTTCTGTTCTCTTATTTGCTTAACATTAAGACCCTTTTTTTCAGTAGAGACGGATAATCTCGAGGACTCCACTGAAACAAGTGCACAAAATGAGCAGCAAGGTGGTATCCCGCAG[C/T]GAATGAGTGTTTCCGGAGCCAATAGGAGGATGATCCACTTGTTGAAGAGAGCCAGAGTTCAACTCATTAAAATTGACCAACAAAAGCAGCTCAAATCAGCTCAGGTCAGAAGGTTTAATGTTTCGGTGACTGAAATGTATGTTTTATTGAGTTTTGTCCAGTAATCTTCAACCAAAGCAAAAAAGATAACTAAAAAGAGTTTCATGTTTGAATATAAAAATGAAGGAATATATTTAGACCATTAAAATGAGCAAAAGGCTGTTCAAATAAATACAATTTTAACAATAATAAAAAACATCAAAATATATTAGAATTAAAATATATATTTGAAATTGTAATCAAATTTCACAAGATTGCATTTTATTCTGATTTTATTCCGGTGGAAAAAAAGACTTGAAATACAAAACTAGTTTTATTTAAAATTAATTTTTGTTATTCTTGGATATCATCTTGTGCATTTTTGTACATGTGGGTGTTCTTTAAATTATAATAGAGATAAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa15376
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000091588 | Nonsense | 1017 | 2863 | 12 | 37 |
| ENSDART00000136957 | Nonsense | 57 | 1897 | 2 | 27 |
| ENSDART00000147922 | None | None | 801 | None | 7 |
Genomic Location (Zv9):
Chromosome 19 (position 9873986)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 19 | 9332525 |
| GRCz11 | 19 | 9251450 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GGAGGCTTGAGTATTCTCACTTCAGTTCCCATCATGCCCCAGTGTGTTTG[T/A]CTGCTCTGTGCCAGCAAAGGCCAGCATGAGGTAAGATKCAACACYMTTGA
Long Flanking Sequence:
TCCATCAAAGAAGACCAAACGCAGGCTGCAGTTGCGGCTGAAGCGGCTGCCGGCCAGTGTTGTGCAAGCGGCCATGCTGGGCTTGACTTTACCACAGAGCGAGTCACAGAGAGTGCTGTGTGAGGAGCCAGTTTTCACTCATTGCTCCTCTGTTACTCATTCTCAGAGTTCGGTCGAGCACACGCCGTCCAGCGTCCTCACTCCACTGTCCAACGGCTGCACGCAGAGGGGAAAGTTGTCACAGGGGTCAATGAACAAGATTCGGGTGGACTTTAAGGTCAGGCATCTTATTTATACTTTACAATATATATATACATAAAAAATGTTGTAAATATAACGAAAACGTTTTGAATTCCTTAATGTGACTTAAAGAAAAATTATATTCGGTTTTACTTAATGTTTTTATGAATGATGCAGGAGGACTGCAATATCCAGAATGTGTGGTTGATGGGAGGCTTGAGTATTCTCACTTCAGTTCCCATCATGCCCCAGTGTGTTTG[T/A]CTGCTCTGTGCCAGCAAAGGCCAGCATGAGGTAAGATTCAACACTATTGAATCTTTAGCCATATTCCTTCATTTTAGTTCACAGAACTAGTGTTGTCAGGATACTGGAATTTGGTACCAATTGGTGAAATTTAAAAATGTTCAGCTAACTTTTGAGCGCTGTTTGCATGTTCTTAAACAGCACTAGTTTGCCGTTGTGTTCATGTGCCAAAATGACTGTGATTGGCCGTGAAGTTCGTCAGTTCACCAAACCCGCCACTGTTTAATGAGTGTAACCACAGATAGACGGACACTAAAGTGTTTTACAAACACAAGATGAGAGACAATAATTATCCTTTATATAAGGATGGAGCAGTTGATCGAATAATACATGTATATACTGTAATGTCATTGTTGAATGTCTAGTTACTTTTCGTTCACCTTGTAAATAGCATATCTAATTATATGTAATGTTTTTTATACATGTTTATAAGACCCTGGATGTACGAATGAGCATTTTGA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa36784
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000091588 | Essential Splice Site | 1027 | 2863 | 12 | 37 |
| ENSDART00000136957 | Essential Splice Site | 67 | 1897 | 2 | 27 |
| ENSDART00000147922 | None | None | 801 | None | 7 |
Genomic Location (Zv9):
Chromosome 19 (position 9874018)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 19 | 9332557 |
| GRCz11 | 19 | 9251482 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATGCCCCAGTGTGTTTGTCTGCTCTGTGCCAGCAAAGGCCAGCATGAGG[T/A]AAGATTCAACACTATTGAATCTTTAGCCATATTCCTTCATTTTAGTTCAC
Long Flanking Sequence:
TGCGGCTGAAGCGGCTGCCGGCCAGTGTTGTGCAAGCGGCCATGCTGGGCTTGACTTTACCACAGAGCGAGTCACAGAGAGTGCTGTGTGAGGAGCCAGTTTTCACTCATTGCTCCTCTGTTACTCATTCTCAGAGTTCGGTCGAGCACACGCCGTCCAGCGTCCTCACTCCACTGTCCAACGGCTGCACGCAGAGGGGAAAGTTGTCACAGGGGTCAATGAACAAGATTCGGGTGGACTTTAAGGTCAGGCATCTTATTTATACTTTACAATATATATATACATAAAAAATGTTGTAAATATAACGAAAACGTTTTGAATTCCTTAATGTGACTTAAAGAAAAATTATATTCGGTTTTACTTAATGTTTTTATGAATGATGCAGGAGGACTGCAATATCCAGAATGTGTGGTTGATGGGAGGCTTGAGTATTCTCACTTCAGTTCCCATCATGCCCCAGTGTGTTTGTCTGCTCTGTGCCAGCAAAGGCCAGCATGAGG[T/A]AAGATTCAACACTATTGAATCTTTAGCCATATTCCTTCATTTTAGTTCACAGAACTAGTGTTGTCAGGATACTGGAATTTGGTACCAATTGGTGAAATTTAAAAATGTTCAGCTAACTTTTGAGCGCTGTTTGCATGTTCTTAAACAGCACTAGTTTGCCGTTGTGTTCATGTGCCAAAATGACTGTGATTGGCCGTGAAGTTCGTCAGTTCACCAAACCCGCCACTGTTTAATGAGTGTAACCACAGATAGACGGACACTAAAGTGTTTTACAAACACAAGATGAGAGACAATAATTATCCTTTATATAAGGATGGAGCAGTTGATCGAATAATACATGTATATACTGTAATGTCATTGTTGAATGTCTAGTTACTTTTCGTTCACCTTGTAAATAGCATATCTAATTATATGTAATGTTTTTTATACATGTTTATAAGACCCTGGATGTACGAATGAGCATTTTGAAACAAAAACATTTTTGTACAAATGAAACATTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa23448
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000091588 | Essential Splice Site | 1343 | 2863 | 20 | 37 |
| ENSDART00000136957 | Essential Splice Site | 382 | 1897 | 10 | 27 |
| ENSDART00000147922 | None | None | 801 | None | 7 |
Genomic Location (Zv9):
Chromosome 19 (position 9878488)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 19 | 9337027 |
| GRCz11 | 19 | 9255952 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACAGCCAGGACCCCAAAACCTGGAGCTCAAATGTGCAAGAATTCCCACGG[T/C]ATGAACCACATTTTTCTTACTTTTCAATAATAAGGTATTCTTAGTCAAAC
Long Flanking Sequence:
TTACTGTATCCATTGTATAGTACTGTTTTCCCCCAACATTCAGTATATCTTTGTGTTCAACAGAAGAAACTTTTAAAATGACAAATTTTGGGCGAACTATCCCTTTAAGTGAAAAGTCATCAGTTTCATTGTGAAATACTTTAATACTTATATTTTTAAGCAATGGTATAAATCAGAAACCATGTGTTCTCTCTCATTTTAGAAATCATTTCATGAGGATGTGGTCAAGGTGATGGTGGAAAGACTAAGAAGAGAAGAATATCTTCTAGAGGCACAAAGGCCCACAAGCCAAGCCAAACTGTATTACATTAAGGTGATGTGTCTTATTTACAGCTACAGTAGCTACTGGAATATTTGAATGCAGTGCTTATGGCATAGTGATGTTTACAGGTAGCTAATTTTCAGTGTTGTTGTTTTCACAGCTAGTAGAACAAGTGTTTAGCTGGTTCAACAGCCAGGACCCCAAAACCTGGAGCTCAAATGTGCAAGAATTCCCACGG[T/C]ATGAACCACATTTTTCTTACTTTTCAATAATAAGGTATTCTTAGTCAAACAAATGCTCTGCAGACTGCAGATTAGCCTATTAATTAATACTGAGTCATACCTTACACCAGGGCTTCTCAAAGGCCCCATTCCCAATTCTACACCTTAGCCCTTCCCCTTACCACTACCCCTCGTTTTGCACGTTCCCGTGAAGGGGGAGGAGTATCCTAATTCTAGCTTGAAAGCATAGGTCTAAGGGGAAGGGGTGAATAGCCCTTTGTTTTTCAGGAACACACTCAAAACCTAGGGGTAAGAAAATTTCATCATACATCAACCACAACATCAAGATCGCAGCACCCGGAAGTAAGGAGATCCACAAATTAGTATTTTTTTGTCATTTTTACGAATATTTACAACAAACAAACACGCTTTAATATATTCATAACTGCGTTCGTGTTTTACCATCATGATTAAAAAAAAAAAGCCTAAAATAAAAACCGCTAAATTTTGCGATCTATAAT
Associated Phenotype:
Not determined