ZMP
si:ch211-198g19.1
Ensembl ID:
ZFIN ID:
Description:
Novel protein similar to vertebrate thyrotropin-releasing hormone degrading ectoenzyme (TRHDE) [Sour
Human Orthologue:
TRHDE
Human Description:
thyrotropin-releasing hormone degrading enzyme [Source:HGNC Symbol;Acc:30748]
Mouse Orthologue:
Trhde
Mouse Description:
TRH-degrading enzyme Gene [Source:MGI Symbol;Acc:MGI:2384311]
Alleles
There are 5 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa20281 | Nonsense | Available for shipment | Available now |
| sa40299 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa20280 | Nonsense | Available for shipment | Available now |
| sa33467 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa20279 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa20281
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000089126 | Nonsense | 181 | 994 | 1 | 19 |
| ENSDART00000133184 | Nonsense | 181 | 894 | 1 | 16 |
Genomic Location (Zv9):
Chromosome 4 (position 22578420)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 23921755 |
| GRCz11 | 4 | 23642730 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCGGACAGTAAAAAAGCGGGCGCCATGCGGATCCAGCGCCGCTTCCACTA[T/G]CAGCCCAAACAGGTGTATGTGATCGCGCTGCACAGAGAGATGAAGCCCCT
Long Flanking Sequence:
TCCGATCAGTGGGCCGACAGCGTGGTGGTCCGACCCCGGACTACCGAGCAGCACATCACGGTGCATAAGAGACTGGTGCTGGGCTTCGCCATCTCCATCCTCACCCTCATCATCGTCACGGCCATCGCCATCACGCTCAGCGTCAGCTTCGAGAGATGCGCCGCGGAGAGCAGCGGGGCTCTGGCCGCCAACGGCTCCAGCAACAGTAAGTGGAAACAGTCACGGGACGGGAACATCAGTCACAGAGACTCGGAGGACGGCCAGCAGCCCTGGAGACACCTGCGCTTACCGGCCACCCTGCGCCCGCGCCACTACGACCTCCGCCTGACCGTGCACATGGAGAACTTCAGCTTCTCCGGCGAGGTGAACATCGAGTTTGAGTGCGTCAACTCCACCAAGCTGATCGTGTTGCACTCGGACCGGCTGGAGCTAGACAAAGTGCTGGTGTTTTCGGACAGTAAAAAAGCGGGCGCCATGCGGATCCAGCGCCGCTTCCACTA[T/G]CAGCCCAAACAGGTGTATGTGATCGCGCTGCACAGAGAGATGAAGCCCCTCAGAACATACAAGATCAACATCACCTTCACCGCGCACATCGAGCACGAGCTGCTGGGCTTCTTCCGCAGCTCCTACATGCTCAATGGAGAAAGAAGGTAAAGGCTGTTTACGGTGTCACTTTCAAAGCCTTTCATATGCTGATTAGGTGTCAACAGTTATCATGGGAACGACAGATGCTGATGCAATCTGCAAGTTACCTCAACTCACCTAACTTGGATCAATTAAGAGCTCAGTGCTTCATACAGCAATTAAAACGGTAAAAGTAAAGCAGTTAAAGTGTTCAATTAGCGGAATTCCACATTAGCTGTTTTGTTTGGGCCAAACATTAGTTACAGTTTGAGAAAAAAACTTTTAAGTTTATATTTGTGTTTATTTTGAGGTTATATTATAAGAATTCGTCATTCGAATTTATGGAATTCTTCACGTTTTGCATAGAATAGTGCAAGTCA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa40299
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000089126 | Essential Splice Site | 636 | 994 | 11 | 19 |
| ENSDART00000133184 | Essential Splice Site | 658 | 894 | 11 | 16 |
Genomic Location (Zv9):
Chromosome 4 (position 22422386)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 23765721 |
| GRCz11 | 4 | 23486696 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATGTGTGTAGCTACTGCACAGTGATTTTCTTTTCATGCTCATGTATTTAC[A/T]GAGGCGCACAGAGTGGGTCACGTGGTTGGTGAGACGTGGTTGCTGGGCAA
Long Flanking Sequence:
TTATGTCATATACATTTAAAGGTGTGTGTAAATGTGTATAACTGCATGACTGACACTTAATGAGAGTTCCCATAAACCTCTCACACCATCTTACACCCCTTCAAGTTGTCACAGTCTGTGTCGCACCACAGACGATCGAGACTCAGAGATTATCAAAAACACATGTATTTATTTACATAATCGCACTTACAACAGAAACTTGGCACACAGGACTTACATGGTGGTTGACACTTCAATCTCGGACAATACAGGTGGTATAAATACACAGGACACAAACACACAGATTACAAACAGGGGTGACACAGGTGGAACTAATGATCATTAACACACAGCGGAAAACAAAACAAAGGGGTCACATGACATAAACACACACACATGGAACACGGCACAATACACTAGACGTGACAAGTGTTACAAATTTTTTTTTTCTGTTTTGCTCAAATCATGTGCATGTGTGTAGCTACTGCACAGTGATTTTCTTTTCATGCTCATGTATTTAC[A/T]GAGGCGCACAGAGTGGGTCACGTGGTTGGTGAGACGTGGTTGCTGGGCAACATCAACCAGACGGGCTACTTTAGAGTGAACTACGACCTTCACAACTGGAAACTTCTTATTCAACAGCTGACGAGAAACCCGACGGTAAAGGACTTGCAATCCCTTTCATCCATCTGTATGTGTGTTTCCATTACGCTTCAAGCTGTGCAAACTGAAACAAGTTGACTAAAATAAACTTAATGGACTTATGCTAAAACTCCCAAATTATGGACAAGGTGGTTCAAGCCATTTTATAATAGTTATATTTCACAAAACTGTAATCACAGTTTTTCACATTTAAAAATCCAACATGTAAAGTCACATGATCAGACTTTATGATGCGTTTATTTGAAGAAACTGCTTCTCTTGGATCCATTGCATTACGCAACTCAAAAAAACTTGATCTGTTCATCTGGAAAATTAAATTATAATGTACCAGAAGCATCTAATATTTGGATACTGCCAGGTAT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa20280
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000089126 | Nonsense | 648 | 994 | 11 | 19 |
| ENSDART00000133184 | Nonsense | 670 | 894 | 11 | 16 |
Genomic Location (Zv9):
Chromosome 4 (position 22422347)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 23765682 |
| GRCz11 | 4 | 23486657 |
KASP Assay ID:
2259-4952.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATGTATTTACAGAGGCGCACAGAGTGGGTCACGTGGTTGGTGAGACGTG[G/A]TTGCTGGGCAACATCAACCAGACGGGCTACTTTAGAGTGAACTACGACCT
Long Flanking Sequence:
AACTGCATGACTGACACTTAATGAGAGTTCCCATAAACCTCTCACACCATCTTACACCCCTTCAAGTTGTCACAGTCTGTGTCGCACCACAGACGATCGAGACTCAGAGATTATCAAAAACACATGTATTTATTTACATAATCGCACTTACAACAGAAACTTGGCACACAGGACTTACATGGTGGTTGACACTTCAATCTCGGACAATACAGGTGGTATAAATACACAGGACACAAACACACAGATTACAAACAGGGGTGACACAGGTGGAACTAATGATCATTAACACACAGCGGAAAACAAAACAAAGGGGTCACATGACATAAACACACACACATGGAACACGGCACAATACACTAGACGTGACAAGTGTTACAAATTTTTTTTTTCTGTTTTGCTCAAATCATGTGCATGTGTGTAGCTACTGCACAGTGATTTTCTTTTCATGCTCATGTATTTACAGAGGCGCACAGAGTGGGTCACGTGGTTGGTGAGACGTG[G/A]TTGCTGGGCAACATCAACCAGACGGGCTACTTTAGAGTGAACTACGACCTTCACAACTGGAAACTTCTTATTCAACAGCTGACGAGAAACCCGACGGTAAAGGACTTGCAATCCCTTTCATCCATCTGTATGTGTGTTTCCATTACGCTTCAAGCTGTGCAAACTGAAACAAGTTGACTAAAATAAACTTAATGGACTTATGCTAAAACTCCCAAATTATGGACAAGGTGGTTCAAGCCATTTTATAATAGTTATATTTCACAAAACTGTAATCACAGTTTTTCACATTTAAAAATCCAACATGTAAAGTCACATGATCAGACTTTATGATGCGTTTATTTGAAGAAACTGCTTCTCTTGGATCCATTGCATTACGCAACTCAAAAAAACTTGATCTGTTCATCTGGAAAATTAAATTATAATGTACCAGAAGCATCTAATATTTGGATACTGCCAGGTATAAGGGACTTTCCTTGCAATCAATGTTTGGGTAAAATGAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa33467
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000089126 | Essential Splice Site | 748 | 994 | 13 | 19 |
| ENSDART00000133184 | Essential Splice Site | 770 | 894 | 13 | 16 |
Genomic Location (Zv9):
Chromosome 4 (position 22401127)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 23744462 |
| GRCz11 | 4 | 23465437 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACCAGTTGGACAAACTCCTGGACCGCACTTTAGACCACAGCCTGTTCAGC[G/A]TGAGTCTGAACTTACATCAGTTTAATGAATGTTGTGTTTTAGCCTTGTCT
Long Flanking Sequence:
AACACGATCTCATTTGACTAGAGCCCAAGGTCCTGCTGTAACACATCTGGGATTTGATGCGCTACTCTAAATGACAGTCAATGTGTGCTGTTAATGCTCATGTCTGTATTTTAGAAGAGAGCTTATGTTTTATGGATTTATGCAAACTGAACATGACTGTAGCCATACAGGAGAAGCTGTTTTTTCTTTTTTTGATTCTTTCAGCACATTATGTCTCCCCACGCAAAGCACAATGCCTGGCAGTTATTCCAAAAGAATAATGATGAACAAAATGAACTGTTTGTAATCAAATGTTAACAATGTGCCAACCAAAGAGGTAATATGAGTTAAAATTTGTCTTTCTTTTCCTCAGAGCTGGATATTTGCCCCAAAACGTCCCCCTGCAGATGATCTCCTATTTGTCTCAGGAGACCGAGTTTCTGCCCTGGCACGCTGCTAGTCGAGCGCTTTACCAGTTGGACAAACTCCTGGACCGCACTTTAGACCACAGCCTGTTCAGC[G/A]TGAGTCTGAACTTACATCAGTTTAATGAATGTTGTGTTTTAGCCTTGTCTAGTCTGATAAGAGATACAGCTGATATCAAGCAGCATGACTTAAATGACTGCCACAAGACAGACAAAACAAACTTCCTCTGATCATCATCCAAAACCAAGGAAATCAAAAAACTGAAAACTGTCAATCAAAACTGATCATCATCCAGTCCACAAAGTTTCTAAACAAAATGGCAATTTCGCACCCCAAAACATAACCACTAGCTGTGTTTTAAGGTGTATTCACACTAGGCAAGGTTGCTTTAAATCGAGCCAGGAATCAATTGCCCACCCTGCCCAACCATACTGCACTCACGCTGTACTTTGCTTTCCAAGTATGAAGACTTATGCATCATTATGATACAATTCCTATGGGAAAGCATATAGAGAAGGGCTCTCGTTTATTGCTATAGAGTACATTGCTGTAAATAAATTGTGGTGTTTTATTTTAAATCATTTGGGATGCAGTGAGAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa20279
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000089126 | Nonsense | 911 | 994 | 17 | 19 |
| ENSDART00000133184 | None | None | 894 | None | 16 |
Genomic Location (Zv9):
Chromosome 4 (position 22382996)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 23726331 |
| GRCz11 | 4 | 23447306 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TACATGTGGCCCGCAATCCACTGGGAAGACATTTAGCATGGAGATATTTC[A/T]GAGAGAAGTGGGACATATTGAACTCCAGGTGAATGTAGTTCTATTCATTC
Long Flanking Sequence:
GTGAATGTTTTGCAGAAAACAACCAATAATTTGGCTCAAATACAGTAGATTGCGATACTTATTGGTTTAGAATAATTTTTAAAGATTTCATTACATTCTTACAAACTAAGGACATTTGGGTAAAACTTTAAATTAAGTTCCAGTTTTCATAATTAACTAGTGGATTGTTACTTGCCTTTTAAGACTATGTAGCCTTTTTTGTACTTATAAAGTACACAGTCTGCATGATATTTTTCTACATCCCTAATCCTACCTACCTAAATACTACATTAACAACCAATAATAAGCAGCAAATTAGGGGTTTATTGAGCAAAAATCATGGTTACCAGTTTGTTAATAGTGAAAATTGTACCTAAAGTATGGCAGAATTTTGTTTTGTTGTCTGCAGGCTCCTGAATCTGTCCCTAACATCAGACCTGGTGCCAGATCAGGATGTAATTGATGTCATCATACATGTGGCCCGCAATCCACTGGGAAGACATTTAGCATGGAGATATTTC[A/T]GAGAGAAGTGGGACATATTGAACTCCAGGTGAATGTAGTTCTATTCATTCCTGCTTATCAGTGAATTTAACCTTCTGTTCAGTCCATGATATGAATTTTACATCCACACTCTCATAAGATATTTATTGGTGAATGTTATTTCTTGTTTGTTGTTGGAGGACCAGAGAAATATCTACTAGTGTTTGTTTACTGCTGGGCTGATTAAAGCCCCCCAAAGTTTTTAATAAAATAGTTTGCGTCTCTCATTCGCAGGTATGGAGAAGCTTTATTTATGAACTCAAAATTAATCAGTGGTGTGACAGAGTTTCTCAATACTGAGGCCGAATTGAATGAGGTGAGTCTGCATGACACCATTTTCAAATAAACAATGGAAAACTTTATGCAATTGGGCCATTCATTTATATGGCATCAACAGTTTGAGAGTCTAAGAAAAGGATTTTGAGATAATCTATAACAGATTTTATAGACAAACTCCCAAGATATCTGCGTTAACAGATAAC
Associated Phenotype:
Not determined