Busch Lab

ZMP

lap3

Ensembl ID:
ENSDARG00000061981
ZFIN ID:
ZDB-GENE-060719-1
Description:
cytosol aminopeptidase [Source:RefSeq peptide;Acc:NP_001108319]
Human Orthologue:
LAP3
Human Description:
leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:18449]
Mouse Orthologue:
Lap3
Mouse Description:
leucine aminopeptidase 3 Gene [Source:MGI Symbol;Acc:MGI:1914238]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa31202 Essential Splice Site Available for shipment Available now
sa19470 Essential Splice Site Available for shipment Available now
sa24839 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa12960 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa31202
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089025 Essential Splice Site 178 517 5 13
Genomic Location (Zv9):
Chromosome 1 (position 18168319)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 18733487
GRCz11 1 19426424
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAGCTCAAGACCAAAAAGAAGGTCCATGTCAAGACCCGACCACATGGGAG[G/A]TACAGTTACACACAAATCTTCCCTAACACACCATAAAAATGTGTCTCTCT
Long Flanking Sequence:
AGACTCTTAAATATTATGGTCTGTATATGTCTGTGATAAATTTATAAAAACATGTTTTTGGAAGTTTCAGTGCTCAATAAGCCTTCACCTATGTGATCAAAAATACATTAAAAACATTAATGTTTAAAATATATATATACACGTTTACAATTTTTCAAAGTATTGGTTTCTATTTTATTTATTTTTTTAATGTAATGTATTTTTATGTTAATAACAGAATTGTCAACATTGTTTTTACAGTCTTACATTTTTCTAGATGTCTTTCAAGAGTAGATGTGCTACTAAATTGAGAGCGTTTTAAATTTTAAATCCACATCTTTTTTTGTCCATATTTGTCCAGCGGGCTGCAGACAGCTTCAGGATTTGGAGGTTGCTCTCGTGGAAGTGGATCCTTGTGGAGATGATCAGTCAGCAGCAGAGGGCGCTGTGCTTGGCCTTTTTGAGTATGATGAGCTCAAGACCAAAAAGAAGGTCCATGTCAAGACCCGACCACATGGGAG[G/A]TACAGTTACACACAAATCTTCCCTAACACACCATAAAAATGTGTCTCTCTCTTTATAAGATAATTCTGTCTTGATTATTTACAGTGTTGATGCAGCAGCATGGCAGAAAGGTGTTCTGTATGGGGATGGGCAGAACCTGGCCAGACAGCTGATGGAGGCTCCTGCCAATCACGTCACTCCCACTGTGTTCGCAAATACTATCGAGCAGAAACTCTCACTTTTTGCTGATAGAGTGATTGTCCACAAGAGGTAGATGCTAAAGATCATTTACTCTATTTATTAAGGATTACCCAACAAATAACATTGTTGGATTGATCTAAATTGAGTGAATGAATTTAAAGATTGTGGCTAAATTCCAATTTATTAAAACACAGGAACAAAATTTTAATTTGTGGTAAAAACTTCTTAATTCAGGGTCACTACATATATACAGTTGTAGTCAAAATGATTAGCCCTCCAGTGATTTTTTTTCTCCTTTTTCAAATATTCCCTAAATGATG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19470
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089025 Essential Splice Site 286 517 7 13
Genomic Location (Zv9):
Chromosome 1 (position 18167011)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 18732179
GRCz11 1 19425116
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGGCACAGCCTCCTCTTGTGCTGGTGGGCAAAGGAATCACCTTTGACAGG[T/G]AACTATACCTGAGCAGAATTTAAACACATCTGTAGTTGTTAAATACAGTC
Long Flanking Sequence:
ATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAAATATTTGATATGTCATGATTTGTTGAGAAACTGAAGTATGAAGTGATGTGAAAAAATTGTGAATGCGACGGACTACAAGCTTTGCATGTTTGTATCAGTTTTATGTCTTCTAAATGCAACTTTTGTCACTGTTTTGGTGCACACTAGCTTACAGATATCCTAAAAACAAATAATACCGATACCAACATCTAAAAACATTATTTTAGTTTCATGTGACCCTTAATTGTGAATTGATCTCTCTCTCTCTCTTTGTTTCACTCTCATTCTGTAAGGCCTCAGTCTTGGATTGAAGGTGAGCAAATGGGGGCTTTTCTCAGCGTGTCTAAAGGCTCTGAAGAGCCCCCTGTCTTTCTGGAGCTGCATTACAAAGGCAGTTCAGACTCGGCACAGCCTCCTCTTGTGCTGGTGGGCAAAGGAATCACCTTTGACAGG[T/G]AACTATACCTGAGCAGAATTTAAACACATCTGTAGTTGTTAAATACAGTCTGATAACCCGTTTGTCTTTCTCATTCCAGTGGTGGTATATCACTTAAACCATCTTCAGGCATGGATGCCATGAGAGCGGATATGGGTGGAGCAGCCACTGTGTGTTCTGCTATCGTGACAGCAGCTGCTCTGAAAATCCCCATTAATATAATCGGTCTGTCCACTGTGTTAGATACTGGAGCTTTTGAATTTGTTATAGTAATAACTATTTATACAGAAATTAAACCTAGATTCCCTGTTTCAGGTTTGGCACCACTCTGTGAAAATATGCCAAGTGGAAAAGCAAACAAGCCGGGTGATGTTGTTCGCGCCAAAAATGGCAAAACCATTCAGGTATTTAGTAACACTTCACTTGACTGTCATAACATCTTTCTAATCATGACATGACACATAGGAGATTTTTGCATGCTTATGACACCTGTCATTTGCTCAGTTATGTCATTTTAAATG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24839
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089025 Essential Splice Site 357 517 9 13
Genomic Location (Zv9):
Chromosome 1 (position 18166626)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 18731794
GRCz11 1 19424731
KASP Assay ID:
554-7604.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAACAAGCCGGGTGATGTTGTTCGCGCCAAAAATGGCAAAACCATTCAGG[T/C]ATTTAGTAACACTTCACTTGACTGTCATAACATCTTTCTAATCATGACAT
Long Flanking Sequence:
CGTGTCTAAAGGCTCTGAAGAGCCCCCTGTCTTTCTGGAGCTGCATTACAAAGGCAGTTCAGACTCGGCACAGCCTCCTCTTGTGCTGGTGGGCAAAGGAATCACCTTTGACAGGTAACTATACCTGAGCAGAATTTAAACACATCTGTAGTTGTTAAATACAGTCTGATAACCCGTTTGTCTTTCTCATTCCAGTGGTGGTATATCACTTAAACCATCTTCAGGCATGGATGCCATGAGAGCGGATATGGGTGGAGCAGCCACTGTGTGTTCTGCTATCGTGACAGCAGCTGCTCTGAAAATCCCCATTAATATAATCGGTCTGTCCACTGTGTTAGATACTGGAGCTTTTGAATTTGTTATAGTAATAACTATTTATACAGAAATTAAACCTAGATTCCCTGTTTCAGGTTTGGCACCACTCTGTGAAAATATGCCAAGTGGAAAAGCAAACAAGCCGGGTGATGTTGTTCGCGCCAAAAATGGCAAAACCATTCAGG[T/C]ATTTAGTAACACTTCACTTGACTGTCATAACATCTTTCTAATCATGACATGACACATAGGAGATTTTTGCATGCTTATGACACCTGTCATTTGCTCAGTTATGTCATTTTAAATGGTGTGGTCAGGTGACATTGTTTGAGATGTCTATGATGTGACAACTTTACATAAATACATCACAACCTGTCTTTACCTTTGTCAAGACAACTTGGCATTACCAAGACAACATGTTATAGAGCTGTCATAAACTTGATTGTCATGAAGACACAAAAAAATGCATCATAAATGTTTACATTTAACTATTTCAGTTGTTTTCAAAAAGTCTTCTTAAAACTAAAAGCATCACAATATAAGTCTTTATGGCAGCATTTACACTGCAGATCTTGATAGTCAATTCCGGTATTGTGTGACTGTATTCAGTGTTTTTGCTGACCTGCTTACATCATCTTTTCAAAGTGACTCGTATCTTATTGTCTGTATTTACACAGCAAAGACCAGGAAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12960
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089025 Essential Splice Site 418 517 11 13
Genomic Location (Zv9):
Chromosome 1 (position 18164680)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 18729848
GRCz11 1 19422785
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCACTGGAGTGTTCACTAAYTCTGATTGGCTGTGGGAGCGGCTRCATAAG[G/T]TAATAATAYGTGATGTGRCTGTCATGTGATTGTCAGAATGACGATTGTCC
Long Flanking Sequence:
ATGACATAACTGAGCGAATGACACTTCATCACGTTTGTTATACGCATGCATAAAATCTTATTCATATTCACAAATAATTGGTAATTTCGTTTTGCATTTATGAACTAAAATATTATGTCATCAAAAATGTCTGCAAAAGACAAATTGCCGAAATGAACTTTCCTGCAGTAGATAGTATTTCTAATATGATGGCCAAGGTATTTCCATTTAAAAAAAGAAGGAACATTATTTTTTCTTCGGTAGATTGACAACACTGATGCGGAGGGCAGACTGATTTTGGCTGATGCTCTCTGTTATGCTCATAGTTTCAAGCCCAGAGCAATAATTAATGCTGCTACGCTCACAGGTACTACATTGATATAGCACACACATTTGTGCACAAACTACATACTCGTAGTAATGGTTTCTCTCTGTGTGCAGGTGCCATGGATGTGGCTTTAGGTTCTGCTGCCACTGGAGTGTTCACTAACTCTGATTGGCTGTGGGAGCGGCTACATAAG[G/T]TAATAATACGTGATGTGGCTGTCATGTGATTGTCAGAATGACGATTGTCCTCATTCACATCATTCTTGTAAATTGTTAGTCTTTGGTTGAGCTGATGTGATTAGTGCACTGTATTTCTTTCCAGGCCAGCGTTGTTACTGGTGACAGGGTGTGGAGGATGCCACTGTTTCAGCACTACACCAAACAAGTAACTGACAGCGCTCTGGCAGACCTGAACAACGTTGGAAAATACAGCCGGTACATTTTTTTATACGTCCCATCCCTCTAATTTAATTGGCCAATGAGCAATAGTAGTCATGGTTTTGCTGAGGTATTCTGTAAACCAGGGGTGCCCAAACTTTATTGAGGCTTGTGGGCCGAAGGTAAATATAGTTGCCCTGGATGATTTCCATAATTTATTTAATAATATTTAAAAAATACTAGAAAACATTTTTTTATATTACCTAATGCAGTATATATATATATATGTATATATATATATATATATATATATATATATA
Associated Phenotype:
Not determined