Busch Lab

ZMP

ppfibp2a

Ensembl ID:
ENSDARG00000061977
ZFIN ID:
ZDB-GENE-070705-277
Description:
Novel protein similar to H.sapien PPFIBP2, PTPRF interacting protein, binding protein 2 (Liprin beta
Human Orthologue:
PPFIBP2
Human Description:
PTPRF interacting protein, binding protein 2 (liprin beta 2) [Source:HGNC Symbol;Acc:9250]
Mouse Orthologue:
Ppfibp2
Mouse Description:
PTPRF interacting protein, binding protein 2 (liprin beta 2) Gene [Source:MGI Symbol;Acc:MGI:894649]

Alleles

There are 8 alleles of this gene:

Allele Name Consequence Status Availability
sa36672 Nonsense Mutation detected in F1 DNA Not yet available
sa16101 Essential Splice Site Available for shipment Available now
sa43125 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa36673 Nonsense Mutation detected in F1 DNA Not yet available
sa43126 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa11866 Essential Splice Site Available for shipment Available now
sa9503 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa36672
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089031 Nonsense 70 826 3 23
ENSDART00000135633 None None 441 None 10
ENSDART00000143617 None None 209 None 7
Genomic Location (Zv9):
Chromosome 18 (position 29100931)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 29173493
GRCz11 18 29151845
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAGGCTCAGGGAGCGAAGATAAGAGACCTGGAGAATTCTCTTGGGGAATA[T/A]CAGCACAAGCTGAACTCCACTGAGGAGATGCTTCAACAGGTATTGGTAAC
Long Flanking Sequence:
CAAACAGCTAAATGTCAGTTTCATAACGATATTTCATAAGAAAAGTTTCAGTTGTAGTATATCAAATAACCGAAGAAAGCCATTGTGCTACATGTGTACAAAGTGCGCCTATCCAAGCCAGTGTAATTGTAATGATTCATGGGAACAGACAGGGCTTTGAGGATTAGTCTTGTTCTGGCTTGTTGGGTTTTTGACAGTAAGTAAAGGTGCTTGGACTGTATATTCCTGATTAACTAGGCTGTCAAGAAGATATTGGATTGCTTTAATTTGTCTGAGGCTCTGTATAATACAGTGTTTTTAATCCAACCGATTATATATTTATGTAGTGTGACTATTATTAATTTGATAAAACTGCAAAGAAATTGACAGCTTTATCTTAGGTGATGCATCTAAATTGAACTAACTTGATTTAAACCTGTTTCTCAGGTCAGTGTTTTGACGGATCAGGTGGAGGCTCAGGGAGCGAAGATAAGAGACCTGGAGAATTCTCTTGGGGAATA[T/A]CAGCACAAGCTGAACTCCACTGAGGAGATGCTTCAACAGGTATTGGTAACATTTACATACATAATAGAATATTATACTTTACACATTGCCATCCTAGAATTATAAGGTTCTATCTGCCATTTTTGTCAAAATTGAGTTATTCAAAGCTTATTAAATGACATCTTACTTACATTATGGGATTGTTGTTTACATTTCAGGATTTAAAAAAAAAAAGAAAAAAAAAAGTTTTATCTACCAAGTTGAACTCAAGTTTGGCTCTAAAAGATTCTTTTTGTGAGTCTATCAGCATTTCAAAAGCACGCACAAGGACCAATCAGGACCAGTTTTCTTTGTCATTCTGCCAGACTGCTCCATTGCTAGTGGGAAAGACCAGAAAGAAACACAAGATCAGAGTCGACTAAATAATGCGAAGAATTAAACTAAAAATTGAGAAGAAACCTGAAACTGAAAAGATGTGTATATTAAAAGTAAATTATTTTTATTTGTGTATATATACTAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16101
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089031 Essential Splice Site 179 826 None 23
ENSDART00000135633 None None 441 None 10
ENSDART00000143617 Essential Splice Site 81 209 None 7

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 18 (position 29112526)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 29184783
GRCz11 18 29163037
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTATGGCAGTGAGCCAGCACAAGCTTCTCAGACWGAACCAAAGCCGACGG[T/C]RAGTCTGAGATCTGGACATTTAGACAAATGTAAACAKTCTGGAACTGTGG
Long Flanking Sequence:
AGTTAAAAACTAAAAGAGCACTTTAACCTTTTAGTAGATTTGGAAACATATTCCAAAATTAATCCTATATTAAAGCATAATGATAAAATGTTGATTGCAGTGCATCATTAGTAATAGTATGGGGTAAAAACAGTAATCCAGGAAAGGAAATAATGGGATTTACATCTAGCAAACATAAACCGATACAAATAAGAATAGATATTAAACATAGTAGAGTAGTATATCTGTACAGTAAGTAACCCAGTAGGAAGCCACTGCTTGTCTGTCTCCTATAATCCATCTTTTCCATTACCTTTTTTTATCTGTTCCTCCTCTCCTCCCCATCCATATCCCTCTTTGACAGAGTGTAGTGAATCTGATTAGTGAGCTCCAGGAGCAGATGTGTAGGATTCGTCAGGAGATCTCAAGTAAAAACCCAGAGAAGCCAGCAGAGATGATCCCAGAGGAGGGCTATGGCAGTGAGCCAGCACAAGCTTCTCAGACTGAACCAAAGCCGACGG[T/C]GAGTCTGAGATCTGGACATTTAGACAAATGTAAACATTCTGGAACTGTGGCCATTGTGGAAAAGAAATACTTGGAAGCCCTTTGATCTTAAAGGTTAAAGTCTGTGATTACTGAAAAAAGGTTTCCAACTTTTATATGCATGCATTGTTATTGATTAATGATGTTTGTTTTAGTTCGTGCTCTAATCAAGGACATTAGTGACCACCCACATCTGCTGCTAGGCATTGGTTCTGCAAGTATTTAGCTTTTTTGTCCAAAATATTTTGAATGCTTTTTTAGATGCTGAGGTTTTACAGATGTCTTACTGAATTTCTTAACTGTGACTGAAAAAGTTTTATTTATTTTTATTCTTTTTTTATTGTAATCTGGATTTCTCTCATAATATTATATTATCTCATAAAGTTATTTCACGCATTTCATGTTTTAATGATTATGAATTTTATAAAAAAAAAAAATTCTACAGAACCATGTTGCTTTGCTTGTTTACCATACAACTTGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43125
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089031 Essential Splice Site 416 826 15 23
ENSDART00000135633 Essential Splice Site 31 441 2 10
ENSDART00000143617 None None 209 None 7
Genomic Location (Zv9):
Chromosome 18 (position 29136313)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 29208570
GRCz11 18 29186824
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAATTTGTTGTTTTGTCATGCTTATTGATTCACTCTCATTTTTGCTTTAC[A/T]GAAACAATGAAGGACACAACCAATTCTGATCTTTCTTCAGTATCGTCTGG
Long Flanking Sequence:
CTCCCTGCAGATTTCAGTTGCAACCCATATGGAACACACTTCCCTGCAATTAGCAAGTGCTGTTCAGTTCCCAAGTAATTGGTTCAGGTGTGTTTGATCAGGGTTGAAGCTAAACTCTGCAGGAAGGTCGATCTCCAGAAACAGGGTTAAGCACCCCTGGTTGCTTGTTCTTGCAACATTACCTGGCTACAGGCAAATCATTTAACCAACAAAAAAAATAATAAATATGCTGTGTGTAGGAAGAACTTTGAAATGAGTGCTAGTCCCAATTGGAGATGATGACTAATTAGAAAACACATGAAAATAAAGCATGTCAAACCATACTCTCAGAAACTAAGAACTATACAAAGAAACTCAGAATATAAATAGCATACAAAGAAACAGCCAACAATGGACTAGTATTTACTAAAAATGCTAAAACTGGAGCCTAAGATATAAACTTACAAAATACAATTTGTTGTTTTGTCATGCTTATTGATTCACTCTCATTTTTGCTTTAC[A/T]GAAACAATGAAGGACACAACCAATTCTGATCTTTCTTCAGTATCGTCTGGGGCTGAATCAGGCCAGCAGTCTCCTGTCTCACAGGAAAATGTCAAAAACACCAGCATACGCAAATTGTGGGGAAAGTGAGTTTATTCATAATAATACAATGCAAATGTGACATTACTATTGAAGAAAACACAATTAAACAATCTCTGCCTTCTCTCTCCTTTTCAAAAAAAAAAAATAATAATAATAATAAAAGGATGAAGAGGACAGGTGTGCTGTCAGATGACTTGGAGCCCACACAGTTTAAGAGAGGGGGGTTCAGGGCTACAGCTGGACCTCGGCTAATACGAACACCTGATTCTGGACGCTCATCTCGGTAGATTTCCCTTTATGAATTAACATGGTCAGAGCCACTTATGTAATAATAAATAATATTGCTGTAATTGTTTTCTTGTCTTCATCAGTTCACAAACACCCTTCTGTAAGTGGACAACAGAGCAAGTGTGTGGCTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36673
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089031 Nonsense 534 826 17 23
ENSDART00000135633 Nonsense 149 441 4 10
ENSDART00000143617 None None 209 None 7
Genomic Location (Zv9):
Chromosome 18 (position 29136875)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 29209132
GRCz11 18 29187386
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGGTTTGGGTCAGTATGTCAGTTTGGCCCGCCAGTGGGTGGATAGTGGA[C/T]AAACCCTCCTCTCTGCAACTCCACAGGAACTTGAGAAGGTTTGTTTTCAT
Long Flanking Sequence:
GCCAGCAGTCTCCTGTCTCACAGGAAAATGTCAAAAACACCAGCATACGCAAATTGTGGGGAAAGTGAGTTTATTCATAATAATACAATGCAAATGTGACATTACTATTGAAGAAAACACAATTAAACAATCTCTGCCTTCTCTCTCCTTTTCAAAAAAAAAAAATAATAATAATAATAAAAGGATGAAGAGGACAGGTGTGCTGTCAGATGACTTGGAGCCCACACAGTTTAAGAGAGGGGGGTTCAGGGCTACAGCTGGACCTCGGCTAATACGAACACCTGATTCTGGACGCTCATCTCGGTAGATTTCCCTTTATGAATTAACATGGTCAGAGCCACTTATGTAATAATAAATAATATTGCTGTAATTGTTTTCTTGTCTTCATCAGTTCACAAACACCCTTCTGTAAGTGGACAACAGAGCAAGTGTGTGGCTGGATGGAGGAGTGTGGTTTGGGTCAGTATGTCAGTTTGGCCCGCCAGTGGGTGGATAGTGGA[C/T]AAACCCTCCTCTCTGCAACTCCACAGGAACTTGAGAAGGTTTGTTTTCATTAGTATGGTATTTTATCTTTAAACCATAGTTTGTCTTGTGTGCTATTGTTTTACCAGCCACAAAAATAAACAATATCCAGGCGATTGTTGTTACAGAATAATGCTCGACAGGCTTAACATTAGATGTTGTATATGACTGAAGTTTTTTTATTTTTTTTATTTGACAACATCCTGGATGAAGTTAATCCCGCATATAAACAAAAACGATATAAAGATTAGACTCAAAACAAAATTAACAATAATAATAATAATAATAATAGTAATAATAATAGTAATAATAATAATAATAATAATTTATATGTTTTTTGGTTAAAAGCAAAGCTAACAGAAACAAAAATGGCTGAATGGAGCATACTTTATCTTATTTATTATTCAGTCACAAGATGTTGACAAACAGTGGCATGACTAGTGTCAGCCTCAGATGTCACACTAAGCACCACTCTTGGACCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43126
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089031 Essential Splice Site 583 826 18 23
ENSDART00000135633 Essential Splice Site 198 441 5 10
ENSDART00000143617 None None 209 None 7
Genomic Location (Zv9):
Chromosome 18 (position 29138526)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 29210783
GRCz11 18 29189037
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TAACAAGACAATGGAGAAATCTTCCGAACTGGATCATATCTGGGTTACAC[G/A]TATGTAATAATCTTAATATTTTAAACTTAATGAAGCTGAACTGTTGCCCT
Long Flanking Sequence:
ATAGCCAAGTAATAAGTATACAGACATCCCAAGTTGGGAAAAGTGACTTCCGGGGGGAAAATACATGATTTGTGGGAGTTGTTTTTGTTGCATGATGTATATGAAGAGTGGTGGGTTGGTGGGGTGGGTTTGTGGTGCTTTTGTATTTGATGAGCTGGGAGTGAAGGGGTTAGGTTGGGCAACATATTTGAAGAGCAAGGGCGTATTTGAGATACTCACGACTTAAGGTAGATTATTATTTCGGGAGTCTCTATGCATATGCGGGAGACTCCTGGAACGTCTGGGAGACTTGGAATGTCTGAGAATATATGGTATATCCACCATGCAATAAAGTCTTTCTGAAACATTAGTAGTACTAATAACGTGTCTTGTGCTCTGTTCTGAATAGGAGATTTGTATTAAACATCCTCTGCACAGAAAGAAATTGCAACTAGCTCTCAGAGCATTCAGTAACAAGACAATGGAGAAATCTTCCGAACTGGATCATATCTGGGTTACAC[G/A]TATGTAATAATCTTAATATTTTAAACTTAATGAAGCTGAACTGTTGCCCTCTGTGGAGTTGCACTACAGCTAAGTCACAACTTGCACCATCAATAACAGCTTGCGATACAGTACATTTTGCTTAAACTGCATGTTCATAAATGAAATTTCATCTGTTTCTGTTTGCCATTTCAAATAAATGCATGTGTTCTGCCAATATTTTCCACATCCTTATTTGCTGTAGGTTGGCTTGATGACATTGGTTTACCACAGTACAAAGATCAGTTTTATGAAAGTAAGGTTGATGGGCGCATGCTACAGTACCTAACAGTGGTAAGATGAAGTTAATTTTACCCCTGTGTAACAACGTTTTCATCTAGGTGAACATGAGTTTGTAAAATGTTAAAATGATGTGCTTTTCTCTCAGAATGACCTCTTGTTTCTGAAAGTCACCAGTCAGCTTCATCATCTGAGCATTAAATGTGCAATCCATGTCCTTCATGTTAACAAGTTTAACCCAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa11866
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089031 Essential Splice Site 584 826 18 23
ENSDART00000135633 Essential Splice Site 199 441 5 10
ENSDART00000143617 None None 209 None 7
Genomic Location (Zv9):
Chromosome 18 (position 29138527)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 29210784
GRCz11 18 29189038
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ARCAAGACAATGGAGAAATCTTCYGAACTGGATCATATCTGGRTTACACG[T/A]ATGTAATAATCTTWATATTTTAAACYTAATGAAGCTGAACTGTTGCCCTM
Long Flanking Sequence:
TAGCCAAGTAATAAGTATACAGACATCCCAAGTTGGGAAAAGTGACTTCCGGGGGGAAAATACATGATTTGTGGGAGTTGTTTTTGTTGCATGATGTATATGAAGAGTGGTGGGTTGGTGGGGTGGGTTTGTGGTGCTTTTGTATTTGATGAGCTGGGAGTGAAGGGGTTAGGTTGGGCAACATATTTGAAGAGCAAGGGCGTATTTGAGATACTCACGACTTAAGGTAGATTATTATTTCGGGAGTCTCTATGCATATGCGGGAGACTCCTGGAACGTCTGGGAGACTTGGAATGTCTGAGAATATATGGTATATCCACCATGCAATAAAGTCTTTCTGAAACATTAGTAGTACTAATAACGTGTCTTGTGCTCTGTTCTGAATAGGAGATTTGTATTAAACATCCTCTGCACAGAAAGAAATTGCAACTAGCTCTCAGAGCATTCAGTAACAAGACAATGGAGAAATCTTCCGAACTGGATCATATCTGGGTTACACG[T/A]ATGTAATAATCTTAATATTTTAAACTTAATGAAGCTGAACTGTTGCCCTCTGTGGAGTTGCACTACAGCTAAGTCACAACTTGCACCATCAATAACAGCTTGCGATACAGTACATTTTGCTTAAACTGCATGTTCATAAATGAAATTTCATCTGTTTCTGTTTGCCATTTCAAATAAATGCATGTGTTCTGCCAATATTTTCCACATCCTTATTTGCTGTAGGTTGGCTTGATGACATTGGTTTACCACAGTACAAAGATCAGTTTTATGAAAGTAAGGTTGATGGGCGCATGCTACAGTACCTAACAGTGGTAAGATGAAGTTAATTTTACCCCTGTGTAACAACGTTTTCATCTAGGTGAACATGAGTTTGTAAAATGTTAAAATGATGTGCTTTTCTCTCAGAATGACCTCTTGTTTCTGAAAGTCACCAGTCAGCTTCATCATCTGAGCATTAAATGTGCAATCCATGTCCTTCATGTTAACAAGTTTAACCCAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9503
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089031 Essential Splice Site 696 826 21 23
ENSDART00000135633 Essential Splice Site 311 441 8 10
ENSDART00000143617 None None 209 None 7
Genomic Location (Zv9):
Chromosome 18 (position 29140296)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 29212553
GRCz11 18 29190807
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTGAATATGCTCCAAACYTGAGAGGCAGTGGTGTTCATGGAGGCCTAATT[G/A]TGAGTCCCAGGGGCTACATACATATGAGGGGGYACCACACAAACTACTTG
Long Flanking Sequence:
ATTTAAACTGCTAAGTGTGAGTGCTCCAATTCGGGCCCAGGTGTGGTTCAGTTGGCCAACCCTGGCCCAGTTGGAATAGGTGTGCCACAGTGCGGTTCAGTTGGGGTTTGGCGTGGTAGGATTGTAGTGTGAGTGCAAAGCGTGCCTGAGTGCGAAACTGAAGATGCAACTTCACATTTAAGGGACTTCATATGGATTTATTATTCATTCCTTTTTTTTTTTTTTTTAAGATTTATTTTTGCCAAACAAGCTTTATAATCAATCATCAGCTAAGTGTCAACTCTTAAAATGTAAATTTTAGGGTGAAATATCCCCTTAAGTTAACATTTTGTTAGAATTCACTGTTTTAAACTAGATTTAATTCCATTCTGCAGTTCAAGACGTCTCCTTCTGAGGTGGTGCAGTGGTCCAACCACCGTGTGATGGAGTGGTTGAGGTCGGTGGATCTGGCTGAATATGCTCCAAACCTGAGAGGCAGTGGTGTTCATGGAGGCCTAATT[G/A]TGAGTCCCAGGGGCTACATACATATGAGGGGGTACCACACAAACTACTTGTTCTCCCGTAAAACAATTTATGATCCAATTACAGATGTCTAATCAGGTTCTGATACACAATCTGTTTTTTTTATATTTACACACTGTGTAAGTATTGTACTTTCACTTGAACAAAGAGTGTAAAGTGTGGATGAGTTTTCACCTTTTTTTTTAGTTCCAAATCGCAAAAAAATATAAAGCTTAGAAATATTTACTGCAAAAAAGACCAAACACTCATTGTTCTGATTAATGAATACTTAATTTATACTTAAAATTAATAAATAAAGTAATACAAATACAATCTTTAATTTCAATTTCAATTTTTCTTTTTTTTTTTTTTTGCAGAAGAAAGTCCATGTTTTAAATATTTTGTCGTGAAATATCTGTCTATGTTTTGTGTTTATGTATTGCAGATCCTAGAACCTCGTTTTCATTCAGAGACCCTGGCGTTGTTGCTTAACATCCCTCCAC
Associated Phenotype:
Not determined