Busch Lab

ZMP

apbb2

Ensembl ID:
ENSDARG00000061880
ZFIN ID:
ZDB-GENE-090313-73
Human Orthologue:
APBB2
Human Description:
amyloid beta (A4) precursor protein-binding, family B, member 2 [Source:HGNC Symbol;Acc:582]
Mouse Orthologue:
Apbb2
Mouse Description:
amyloid beta (A4) precursor protein-binding, family B, member 2 Gene [Source:MGI Symbol;Acc:MGI:1084

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa16258 Nonsense Available for shipment Available now
sa32652 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa611 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa16258
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000088750 Nonsense 589 890 8 15
ENSDART00000138796 Nonsense 564 863 10 17
ENSDART00000146232 None None 138 None 3

The following transcripts of ENSDARG00000061880 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 18711676)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 19273510
GRCz11 1 19966447
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TCGCTGTAAACAACTGCATYCGTCAACTGTCCTACTGCAAGAATGAYATA[C/T]GAGACACTGTGGGCATCTGGGGAGAGGTGAGCTACAGCTACACACACACA
Long Flanking Sequence:
TAACTCATATATAGGCATGGACAAGGAAATTAAAGAGCACTTGAAAACTCTCCTGGAGTACTGGAAGAGCATCCGCTGTGTAAAATATATGCTAGATAAGTTGGTGGTTCATTCCGCTGTGGCGACCTCTGATAAATAAAGGGACTAAGCCGAAGGAAAATGAATGAATGAACGAACGAAGGAATGAATATCATTTTGTTTTAATTTCTTGACATTAAAAATCAGGGATAGCTTGGCATATATTGGTATTGTGTTGTCTTAAAAAGTAATACAAATCCGTCTGAATATAACAATAGAGTATGTTTTTATCTTTTTTTTGGCAAAAAGGAAATTCTCTAAATGAAATGTTTCATCAGTGGGTGTGTTTTTTTTTATTCCAGTGTTTTGCCGTGCGCTCTCTCGGTTGGGTAGAGATGGCTGAAGAGGATTTGGCTCCGGGTAAAAGCAGTGTCGCTGTAAACAACTGCATTCGTCAACTGTCCTACTGCAAGAATGACATA[C/T]GAGACACTGTGGGCATCTGGGGAGAGGTGAGCTACAGCTACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACAGAAACAAATACATTTCTAAAAATCTTTTGCACAATCTTTGCACAGTTTTACCAGAACCTTTGAAGTTTGAAATAGTTCTGCTGCTTTACACAAATATTTTTTTTAATATCCATATGCTGGGGCAAAGGAGTGGCGCAGTAGATAGTGCTGTCGCCTCACAGCAAGAAGGTTGCTGGGTCGCTGGTTCGAATCTCGGTTCTGTGTGGAGTTTGTATGTTGTCCCTGCCTTCGCGTGGGTTTCCTCCGGGTGCTCTGGTTTCCCCCACAGTCCAAAGACATGCGGTACAGGTGAATTGGGTAGGCTAAATTGTCCGTAGTGTGTGTGTGAATGTGTGTGTGTGTGTGGATGTTTTCCAGAAATGAGTTGCGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32652
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000088750 Essential Splice Site 735 890 12 15
ENSDART00000138796 Essential Splice Site 708 863 14 17
ENSDART00000146232 None None 138 None 3

The following transcripts of ENSDARG00000061880 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 18726084)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 19288062
GRCz11 1 19980999
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAGTTCCAGGTGTTATATGTTGGCATGATGCCAGTTGCCAGACCTATAG[G/A]TGAGCAGATACACTTACTTCATAGTCTTGCACTTACAGCTTTCATGCTCA
Long Flanking Sequence:
TATACAAGAGTTATTATTATGGATTATAGATAGCTAAATTTATTGTTTTTGATAGTTTTTTTTAGCATGATGCTCAAACATGAACGCCGTTATGAATGTTTTAAAAATATGTTTGTTGTAAAAATTCATAATCATGACAAAAAATACTAATTTGAAAATACTAATTTGTGCAGCCACACCTTCAAGCTAAAGAGAATTGAGACAGGGTAAGGGAAAAGGGCTAAAGGGTAGAATTGTGATTTGGCCATTATTTACATTTTTTCTTTATTTTAGATCAAATAAATGCAACCTTAATTATTCTAAATGAATACAATTATATTATCATCTCAATTATTCCAGACCTTGTGCAGTTGTGTATGCTTTTTTGTCTTGAGAAACCAGTGTGTATTAATGTGTATGTTGTGTTTTATTCTCAGCAGAGTTTCCCACACCAAAGACTGAACTGGTGCAGAAGTTCCAGGTGTTATATGTTGGCATGATGCCAGTTGCCAGACCTATAG[G/A]TGAGCAGATACACTTACTTCATAGTCTTGCACTTACAGCTTTCATGCTCACTCTCTCTTTTTAACACCTTCATGCTGCTTTTCTTTATAACAACAATTCCTCTAGGTCAGACTTAACAAAACAGTATCAGGCAGCTCAGTCATAGGTTTGATTTCTTGCATCTTTCTTACATCAGTAAATGAAGCAATAAATTGGTCATACATTTTTATCTGATTGTTTACAAGACAAACACAGCCTGCTGAAACTAGGAAACAAACATTCGTTGTCATGTCTTTATTAAAAAATATTTTAATAGCTGGCTGACCTTCCACTAAATCACCTATACAAAACTGCTGTTACAAGAAGTTTTACAGTTCACTAATGTCTAATAATTTAGAAATGTCAAATATGCATAACAGTTCTTCTTCTGTAGTTCTTTCCATCTTCATGCAAGTCAGGAACAGTTCTTCATCTTAAGCTGTTTTTGAATGGGATTAGTTGTAGATAGAGAGGTGAGGTAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa611
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000088750 Nonsense 837 890 15 15
ENSDART00000138796 Nonsense 810 863 17 17
ENSDART00000146232 None None 138 None 3

The following transcripts of ENSDARG00000061880 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 18734009)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 19295963
GRCz11 1 19988900
KASP Assay ID:
554-0521.1 (used for ordering genotyping assays)
KASP Sequence:
ATCCTCTCACTTTTTGACTCTTTTTCTCCTTTATGTCTGCAGTTGAGGTA[T/G]CAGAAGTGTCWGGTGGCGCGTCCTCCATCTCAGAAAGCCTGCTCACAGGC
Long Flanking Sequence:
CGCTTATCCGCACACCTCTCAAAAAAATTTAAACTACACGTCGCACAGGCTTTGTAATTGGTCAGTTTGACAGCAGTAACGGCCTGGATTAATTTGTTGTTCAATGTTGAAGTTTAATAAATAGTTTAATAAATAATCATAGACAGTAGATAGTGTGTGTTTCTATCAATTGTTTTAAAATCAAGTAATGCAACCTTCCTTAAAAAATCTCTCACTGGTAATATGTGAACTTATTTACTGTACAAAACCTGTCAGTGAACTATGAAGGCAAAAAAATAAAATAAAATAATTGTTCATTATTTATAATTAATACGAGTTAAAAGTATAATGTTTAGTTAAAGTATAATAAAAAGTACAATATAGAGTTAAAATGTTCAAGTAATCGAGATTTTGATAGGCCAAATCGCCCAGCCCTACAACCCAGCCTGTATTATTATACTCAACACATACATCCTCTCACTTTTTGACTCTTTTTCTCCTTTATGTCTGCAGTTGAGGTA[T/G]CAGAAGTGTCTGGTGGCGCGTCCTCCATCTCAGAAAGCCTGCTCACAGGCGGCCCCTGCTGATTCAGTCACCCGCCGCGTCTCCACCAGCGTCAAACGTGGAGTTCTGTCTCTCATCGACACGCTCAAACAGAAGAGACCCGTCACTGAGCTGCCTCAGTGATCTGACACGCACACTCACCGTCACGCTCTGCATGCTTATAACTATCCGAATGTCCTGTACATACCTGTCCGGTCACATGGTGGAGATGAAGAGGATCACAAGGATGAAAAATCAGAAAATAAAGCTGATGCCAAGAAAATACACCCTTTACTCACACACTCACAAGTACATCAGATCTACTATACAAGCCTCTCTCTCTTCCGATGTCAATCATGCATATATTTGCATGGGAAGCCACGCCTCTCCAGCATGACAGCAATCAACAGGCTCTGCCCACCTAGAAGAACCGCCTCATCTAGAATAAGCCTGATCAAAGAGAGAACTTGATTGGAAGAATG
Associated Phenotype:
Not determined