Busch Lab

ZMP

si:dkey-110c1.10

Ensembl ID:
ENSDARG00000061810
ZFIN ID:
ZDB-GENE-050208-429
Description:
Novel protein similar to vertebrate myosin VA (Heavy polypeptide 12, myoxin) (MYO5A) [Source:UniProt
Human Orthologue:
MYO5B
Human Description:
myosin VB [Source:HGNC Symbol;Acc:7603]
Mouse Orthologue:
Myo5b
Mouse Description:
myosin VB Gene [Source:MGI Symbol;Acc:MGI:106598]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa37497 Nonsense Mutation detected in F1 DNA Not yet available
sa43819 Nonsense Mutation detected in F1 DNA Not yet available
sa29765 Missense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa37497
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000088542 Nonsense 371 1836 10 41
ENSDART00000132951 Nonsense 366 1031 9 21
ENSDART00000139160 None None 401 None 8

The following transcripts of ENSDARG00000061810 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 22 (position 20601909)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 20258602
GRCz11 22 20283580
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATGACCGTTCCTTGGCAGTCTTTGCCAAGCTTTTGAGGGTGGAAGGTGCT[C/T]AGATGGCCCAATGGCTATGCCACAGGAGACTAGCAGTGGGTGGGGAGATG
Long Flanking Sequence:
CACCAACCAAGGACAAGATGTGCACATTTCGGGTACAGATGATGTAGTCGAGCTAGAGCGGACAAGAAATGCCTTTACTATACTTGGTAAGGTAAAATACACCAATATGCTCCACTATTGCCACATGCTGCATTTTGTAAAAGAGTGTGGTTCATCCCTGCAGGAGTGCAAACAGACCAGCAGATGGAGATATTTCGTATCCTGGCAGCTATTCTTCACTTGGGGAATGTCAACATACAAGCCAGCGGTCGTGGTGGGGACCGCAGCTACATTGATGTACAACCACAATTTCCTATTACTGTGTACATGTCAAAATCCAAATTAAAGAAACAATTTTATGTCTGTATACATTAACATCAGGAGCAGTGCTGTTCTTGCTAATCTAATAACATGCAGAATGTGCTAATAAGGACATAATTTCTTCTTATTCATCAACGTATTGGCAGGGCGATGACCGTTCCTTGGCAGTCTTTGCCAAGCTTTTGAGGGTGGAAGGTGCT[C/T]AGATGGCCCAATGGCTATGCCACAGGAGACTAGCAGTGGGTGGGGAGATGCTTGTAAAGCCCATGACTGGCCAACAGGCAAATGAAGCACGGGATGCTCTGGCTAAGCATGTGTACGAGCAACTGTTCACATGGACAGTGCAGAGGCTCAACTCATCCTTACGAGCACACCGGGAAAAGCCTAAATCTTTCACAGGAGTCCTTGATATCTATGGGTATGTGAGTTGTTCTGTACTGTTTTGCAACATTATGGATCACTTTTAACAATCTTTTTTATTGTGTGTAGGTTTGAGACTTTCGACAGAAATAGTTTTGAGCAATTCTGTATCAACTATGCAAATGAGAAACTTCAGCAGCAATTCAACAGAGTAAGTTTCCTGATTTGGGGGATCAATAGGTTCAAATAGTTGTCCATGATCAGCAAGGGTGCCTCTAGTAATTTTAGACCCTATGAAATAATATGCCACCTTGGCAATTTTAATGCTAATAAAGTTGATATCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43819
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000088542 Nonsense 778 1836 18 41
ENSDART00000132951 Nonsense 777 1031 17 21
ENSDART00000139160 None None 401 None 8

The following transcripts of ENSDARG00000061810 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 22 (position 20599323)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 20256016
GRCz11 22 20280994
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGGGTTTTGATCCAAAGCTGGGTGAGAGGATGGCAACAGCGTAGGCATTA[T/A]CAGCGGCTCCGGCAGGCCACATCTATCCTGCAGCGGTACACCAGAGGAAC
Long Flanking Sequence:
TTCTGTAAGAGAAAAATTAAGATGTCCTATGCATTCATTCCTCTAGAGTTTTGAGTAACCTTTTAACCTTCACCATATCAGATTTGATCCCAAGCGAGCTGTGCAGCAGCTGCGAGCATGTGGAGTCTTAGAGACCATCCAAATTAGTGCCGCAGGCTACCCTTCCAGGCAAGTTTACTTGTAAAAGTCTCTCGAATTCAATAACAATAATTTCACCCCCAATTACTTCAACCAAATTCTAGGTGGACATATGAGGAGTTCTTCGCCCGTTACCGGGTGCTGCTACAAGGTTTTGTTTCTCAGGATGATGTGCGCCATTCCTGTCAGAGCACCCTTCCTGATCTTATCCCTGATCCGGAGCAATACTGCTTTGGCAAGACCAAGGTTTTCTTCCGGGCTGGGCAAGTAGCGGTTCTGGAGAAGCTTAGAGGAGATCGGCTACATGCAGCAGGGGTTTTGATCCAAAGCTGGGTGAGAGGATGGCAACAGCGTAGGCATTA[T/A]CAGCGGCTCCGGCAGGCCACATCTATCCTGCAGCGGTACACCAGAGGAACCCTGGCCCGAAGGTAAGTTTAGAGTGACCTAAAGAAGAACATGAGTTTTTTTGGTCTCATGCTAATTATTTACTTTGTTCTTATATATCTTTTTGTATATTTTTTAATCTAATTGGAAGTATGTACTTTAATGTTATCCGATCAGGTTGGCGTGGACCCTTCGTTATACACGTGCTGCTTTAATCATCCAGAAAACATACCGCATGCTGGCTGTGCGACAGCTTTATCTGACCATCAGAGGGGCCACCATTAAAATCCAGGCCTTCATCAGAGGAACCAAGGCTCGTCGCATTTATTCACAGGTACAGATAATGAAATCAAAATTTACAATGTTTTTTTTGCTAGCACACATTATTATACTTGGGCGAGGCAGTGGCGCAGTAGGTAGAGCTGTCACCTCACAGCAAGAAGGTCGCTGGTTCGAACCTTGGCTCAGTTGGCATTTCTGTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa29765
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000088542 Missense 1359 1836 30 41
ENSDART00000132951 None None 1031 None 21
ENSDART00000139160 None None 401 None 8

The following transcripts of ENSDARG00000061810 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 22 (position 20579147)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 20235840
GRCz11 22 20260818
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATCTTCAGCAGCTACAAGACAGAGACATGCCTGGAGATCCTGACAAAAAT[G/A]TAGCCAGTCTGTCGGAAACTACTGTTTGATGTTCTTTGGATTTTTTTGTT
Long Flanking Sequence:
TAGTTAAAAGGTGCATTCACAAATTTTTTTCGAAGCCCTAAAGAGAACTCTAATGAGTTTTGTTTGGGCCTGTTATGTTAGAAACTATCTCAGTTTGGTTTTCAGTTTCAGTTAAAGCATATTGCGGCTTTTTATAAATCTAAAATGATGTTTAATAAATCCATAACTAAAAATGTCATAACTAGTAAATGAATATATACCGACAGAGCATGCTGATGGAGGATATGAGTGTTGCAAAGGATGCAGCTGAGAGGATGAAGAGCGAGGATTTCAGACATGCCTACGATGCTATTCGTGTGGCCAACAAGTCAGTTTCCTTCTATATACTGGCACATTACCTTATGAAGTCATCAGTAATTAGCAGTAATGTTTATTTCTCCAGGTTTCTAGAGACGCAGCTGTTGTCTCAGAGAGCGCAGTGGGAGCAGGAGATTTCAGCTCTCAGGACGAATCTTCAGCAGCTACAAGACAGAGACATGCCTGGAGATCCTGACAAAAAT[G/A]TAGCCAGTCTGTCGGAAACTACTGTTTGATGTTCTTTGGATTTTTTTGTTCAGTTGTTATTTTTTTTTCTTCGTGTATGTGTGTCTGAAGGATCTAATGGAGCAGGTGATGGTTCGAGAGCAGGAATGTGTCCGATTGCGGCGTGAGCTTAAGGAGCTGAAACATACCGTGAGCCTCAGGAGAATTCTGTCTTATTCAGGTCTGTGTAGCTCCAAAAAGTATTTTGACAACTAAAACATTATTTAAAAAAGTAGTTTTCCCAGTGGTGCTAGAGAATGGCTCTTTTGGAGTGTTCTTAAATAGTTTTTGTAGCATGAGGAACATTAAAGTCTGTGTGAAATCAAAATTTACAAAGTTTTTATTGCTAGCGCACATTGTTATTATTTAGGTAAACAATTAATCCATGCAAGTTATTTACACTAAAAAAAAATTGGTTTGGTAATCTTCAATCAAATTCGCTTCTCCGTTTGGAGTGGTGGACCTTCTCTGTTGACATCAGT
Associated Phenotype:
Not determined