Busch Lab

ZMP

kdm6a

Ensembl ID:
ENSDARG00000061759
ZFIN ID:
ZDB-GENE-081105-56
Description:
Novel protein similar to human and mouse ubiquitously transcribed tetratricopeptide repeat, X chromo
Human Orthologues:
KDM6A, UTY
Human Descriptions:
lysine (K)-specific demethylase 6A [Source:HGNC Symbol;Acc:12637]
ubiquitously transcribed tetratricopeptide repeat gene, Y-linked [Source:HGNC Symbol;Acc:12638]
Mouse Orthologues:
Kdm6a, Uty
Mouse Descriptions:
4lysine (K)-specific demethylase 6A Gene [Source:MGI Symbol;Acc:MGI:1095419]
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Gene [Source:MGI Symbol;Acc:MGI

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa17907 Essential Splice Site Available for shipment Available now
sa34686 Nonsense Mutation detected in F1 DNA Not yet available
sa7197 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa17907
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000088469 Essential Splice Site 294 1437 None 30
ENSDART00000144623 Essential Splice Site 294 471 None 14

The following transcripts of ENSDARG00000061759 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 34792156)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 34025184
GRCz11 9 33834369
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TCTGTAACTTTCCTAAAAGTCTCTATATTTGGTGTTTTCGTTTATCTTCM[A/T]GGTGCTACTCAAGTATTGGGAAGGTTCAAGATGCCTTCATATCTTACCGA
Long Flanking Sequence:
TGCTCCCTCAGGCTGGATGCATCACACGGTCGAACAGTTGGGAGATAAAGCAAACAAGAACAGCTATGCTATTCAGTGTCTGCAGAAATCCCTAGAAGCAGACCCCAATTCTGGACAGTCTTGGTACTTCCTGGGCAGGTAAGAAAATATTTATCTTGTGTAGTAATGTTTTTTACCTGATGTTACTATATAACTGATTATATTATATTATATTATATTATATTATATTATTTTTTATGCATTAATCTGAATATTACAGTTAGTGTTTATCTGTTGTTTGAAAACATTTTTGCTGATGTCCTAAAGTAGTTCGTTACAACAAGTTAGTACATTTTGTAAGTTGTTTTTTATTTCCCTGATCTCAAACTGTAAAAGTATGGCACAGACTGATTAAAAGTATATATCTTGAACCCAGTGTATGATGCTTTGGTCATTATCTCAAATTTAAGCTCTGTAACTTTCCTAAAAGTCTCTATATTTGGTGTTTTCGTTTATCTTCC[A/T]GGTGCTACTCAAGTATTGGGAAGGTTCAAGATGCCTTCATATCTTACCGACAGTCTATTGATAAGTCTGAGGCCAGTGCAGATACATGGTGCTCAATCGGGTAAGCTTTTAATGATAGTTTTTTTATATGATTTGACACTCTTTGCTTAAGTACAATGATGTATTATGATAAAATGAAACTTCCATGTCGTTTTGGTAGTTGGGTGTAAAGGGGGTCATGTGGGACTGAGGCTGTGGGTTTCTGTTGCTCTAAGTGGAGAAAAAGAAACCCTCTTGTTTCTAAATATTTAAGCTGAAGCATTCGCCTGCACCCCAGAGCTGTACTCCTCTTTTTATCTCCATTCATAGAACGAAAGTAAGAATGAAATAAATGTTTGCACAACAAAGAAGTAGCCAAAGGCTGAAAGATCTTTGTCTTGTGTTTTGAAAAAAAATTCCCTTTTACACTAGCTTTTTTTTTTTTTTTTTTTTTTAACAATCCACATCTGCAAAAAGGTAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34686
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000088469 Nonsense 550 1437 16 30
ENSDART00000144623 None None 471 None 14

The following transcripts of ENSDARG00000061759 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 34797939)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 34030967
GRCz11 9 33840152
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGCAGCTGCAGATGCTGGAACAGTTGGAAAAGCAACTGAGTCTAATGCAA[C/T]AGAATCAACAGGTAAGGATCATAATTTGTGGCTTGAAACATAAGAAGGTC
Long Flanking Sequence:
AATTAACATTTTCCTGAATTAGTGCTTTTTATTGTATAAATGCATGTTTAGCTGGTTGAGCATGCCATTTGTCATTGTTTCTAAAGGTTTCCAGTAAAAAAAAAAGAAAAAAATCTTTTGCAGAACATCAGTTTTGAAAAATGTAATAAGAAATATTACCAGGTCAGCATATTAAAAGGATTTCTGAGAGATCATCTGGCACTGGAACTAATGGTGATGGAAATTCTGCTTTGCCATTAGAGGAATTAATTACATTTTGAAATATTTGAAAAACGAAATTGCTTTTGAAAATTATAAGTGCTTTGGTGAGCCTAACTATTCAAAACTTTTGACTTGGTGTACTTATGTAAAAGCACATTATATTAGATCTAGAGGCAAGCACACATTTTATCGTATGGTTTATCCAGCTCCTGGAACAGTTACGGAACAACAGAGCCAATCTGAAGCCAGTGCAGCTGCAGATGCTGGAACAGTTGGAAAAGCAACTGAGTCTAATGCAA[C/T]AGAATCAACAGGTAAGGATCATAATTTGTGGCTTGAAACATAAGAAGGTCTGTAAGAAGCTATAAAAGAATTCAAATCATCATTGGTCTCTCTTGCCTTTTAATACACTTGAAGATGTCTTGCCTAAAACTCTTGCTTTCTCCAACAGACAAGGCTGAATGCCATGGGTCAGATACGACCCAGTGTGTCCAACGGTCCTGTAGCCGACTCTTCACTGCCTACAAACTCTAATTCCACACCTTCCCCTCACCATCCACACATCGCTCTGTCTCGCACACCCTCTGCCCTCACACGATGCGCTGCTCAGCCAATAGCCAACGGACCTGTCCCTGCGAGCCCCGTCCCATGCAGCACCGCTGGTACCCTGGGTAACACAGATGCCGTCTCTGTGGGCAATAATCATCTCCCAGGATCGGGGAGCAACGGAAATGTGCCTTACTTGCGGCAAAACGCACTACCTCATAACTGCACAACCCCCACCAGCAGCAGCATGGATGATG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa7197
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000088469 Nonsense 722 1437 18 30
ENSDART00000144623 None None 471 None 14

The following transcripts of ENSDARG00000061759 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 34802952)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 34035980
GRCz11 9 33845165
KASP Assay ID:
554-4768.1 (used for ordering genotyping assays)
KASP Sequence:
GGACGTCCCAGCCTTCCCCGGCAGCCGGCACTGGCGGTCCAAATCAGGTC[G/T]GACATTCGGCCACAGCCAGCGACACGCAAGCGCAGGAGGCCAGTCACAAT
Long Flanking Sequence:
CAGATGTACAAATCTACATTTGCTGACAGACAGTTTGGGCTGCTTATCAAAATTATGGAAAATGTCTGCCTGATAATATACAATTGGAGGAACATTTTTTTAGTCTTGTGCCTTGCCCAGAATATACAAATGCATTTAGATCATTTACTTTAATCATTACTATTGGAATGTGAAGAACTATTACTAGTACTATTGGTGTGAAGAAGAATGTTTCTGAAGACAATCACCATTAACCATTAGTGTTTAATTATTAACCCTAATATATATTGTTTTTCAAGATTTCTAAACAGAAGATTAGCACTTGAGTCTTTTTTTATGTATTTATTTTTATTAAGTAGTTTTCATACATAAGTGACAAATGCTTTCGTCATTCTTTATCACAGGGGCTTCAGAAAAGTCCAGGTTCATATTCAGCAGGTCCTAACGGCGAGCAGCCTTTCTCTTCCACTGGGACGTCCCAGCCTTCCCCGGCAGCCGGCACTGGCGGTCCAAATCAGGTC[G/T]GACATTCGGCCACAGCCAGCGACACGCAAGCGCAGGAGGCCAGTCACAATCACCTCCCCTCCCCGAGCTCCCAGAGCTCTGCTACCTCAGGTGGACAGCAAGGCACGGTGAACACCAAAGAGAGCAAGCCTTCAGGAAACGGGCATTCCGTGGGGACGCCTAACAGCACTGCCACTGCAGAGGGACTGCCTAATCATGTCCATCAGGGCCAGGCAGACACTGCTGGGGCGAAACCCCGTTCACCAGGTGTACTTAGTTCAGACAATCCACAGCTCTCGGCCTTGTTGATTGGAAAAGCCAATGATAGTAATAATAGTAATGGAGGAGGGTCGGCGGCTGCTGGCACAAAGGTTAACAATGTTCACCCGAGTCTGCACAAGCCGCAGGAAAACTCGGTGGCTTCTTCTCCATGTTCTGCCATGTCTGCAGCTTCGCCCTCACCCAAAACTGCAGACCACCACAGTACTCAGAACAGTGTTAACAGCCTTAACAGCCCCACG
Associated Phenotype:
Not determined