Busch Lab

ZMP

nrxn1a

Ensembl ID:
ENSDARG00000061647
ZFIN ID:
ZDB-GENE-070206-1
Description:
neurexin 1a [Source:RefSeq peptide;Acc:NP_001073490]
Human Orthologue:
NRXN1
Human Description:
neurexin 1 [Source:HGNC Symbol;Acc:8008]
Mouse Orthologue:
Nrxn1
Mouse Description:
neurexin I Gene [Source:MGI Symbol;Acc:MGI:1096391]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa15915 Nonsense Available for shipment Available now
sa35299 Nonsense Mutation detected in F1 DNA Not yet available
sa4466 Essential Splice Site F2 line generated Not yet available
sa641 Nonsense F2 line generated Not yet available

Mutation Details

Allele Name:
sa15915
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000056256 None None 419 None 6
ENSDART00000088159 None None 449 None 7
ENSDART00000088178 Nonsense 172 1484 1 23
ENSDART00000093094 Nonsense 172 1491 1 22
ENSDART00000111239 Nonsense 172 1488 1 21
Genomic Location (Zv9):
Chromosome 12 (position 25856160)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 24224836
GRCz11 12 24346055
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTGAACTGCGATCTGTAGCATTACGCCTCACATCTTCAGCCATAAAAGAT[G/T]AGGTTCCCTACAAAGGATGGAYAACCAACCTGAGAGTGAACGGCTCGGAG
Long Flanking Sequence:
TGCGGAACGGTGCACATCTAATCTGGATAGGCCTACTGGTTTGTTGCCTTGTCGACATGGGGGCCAGCATGGAGTTCACTGGTGCAGAAGGCCAGTGGGCAAGGTTTCCCATGTGGAACGCCTGCTGCGAAAGCGAAATGAGTTTCAACATGAAGACCAAAAGCGCTCATGGACTTTTAGTGTACTTTGACGACGAGGGATTCTGTGACTTCTTGGAACTGCTCATCCACAATGGTAGACTCAGTTTGCGGTTCTCCATCTTCTGCGCCGAGCCAGCGACCGTGTTCTCAGACACAGCCGTCAATGACAGCCGCTGGCACGCCGTGACCTTGCGCAGGAATTTCAAAAACACTACTTTAGTTGTGGACGAAGAAATCAAGTGGGTGGAGGTAAAGTCGAAACGGAGGGACATGACGGTCTTCAGCCATTTATTCTTAGGGGGGATACCTCCTGAACTGCGATCTGTAGCATTACGCCTCACATCTTCAGCCATAAAAGAT[G/T]AGGTTCCCTACAAAGGATGGATAACCAACCTGAGAGTGAACGGCTCGGAGCCGGTGCTTATCGGTAGCGATGGAGTCAACAGCGACATTTGCGAAGCCGACCACATTTGCCTGAATGGAGGAGTCTGCAGCATTGTCAACGATGAGCCCATTTGCGACTGCTCTGAAACGGGATTCCAGGGAAAAGACTGCAGTGAAGGTAAGAGGCCTGGATTCGTCGTCTCCGTTGAGGTGTTGAAATGTCTTTTCAAACACAGCCCTTTCACTTCTTTTTTTTTTCAGTTTTCAACATTGCACTAGTTCCTCAGAGGCAGTGCATGCTACATCATGTCTTTTCCCGGCCTCCACATACAGGCCCAATACATTACATGATTAGATTACAGTCAGAGAGTGCCTATTTCAGAGCATCCACAAACACCCTGTGTTTTTGCTAACAATGACGTCAGAGAAGCCAAATTAACTTAATATACTCTTGACACTGCACTGGCATTACAATTAAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35299
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000056256 None None 419 None 6
ENSDART00000088159 None None 449 None 7
ENSDART00000088178 Nonsense 425 1484 7 23
ENSDART00000093094 Nonsense 425 1491 7 22
ENSDART00000111239 Nonsense 422 1488 6 21
Genomic Location (Zv9):
Chromosome 12 (position 25956139)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 24328601
GRCz11 12 24449820
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACTGCCGATCTTCCTGGATCACCTGTCAGCAACAACTTTATGGGCTGCT[T/A]GAAAGAGGTAAGAGATTTGAACAATTGCTCCTCGGAAAAAATCAAATCGT
Long Flanking Sequence:
TGTGTCTGCTGATTCACTTTTGTGTGCTCGATTTAAGTGGCACCGCTAACTTTGAGCCTGGGCTAATGTGCCGCAGACTTCCTCAGATGACTTTACTAGAAGTTAAACACATCAATCTAGAAAGTTAAACCAGTAACAAGTAAGATTTTCTGAAACAGACATGAAAATGGGTTCACATTTGAAATCAATAAAAAGAGAAAAGCAAATAAATAAATAAGAACAAAAGGAAAAAGAAATCTAAACAAATCCAAGCATTCAAATCCTTACGAGGGGGACCAAAGCCCTGTAACAGTATTGAAGTTATATGTGAGTATAGCGTGTCCTTTCCCTGTGCTTTGTTGTCTAGGTTACAATATCCGTGGATGGGATTCTGACCACCACTGGATATACGCAAGAGGACTACACCATGCTAGGCTCGGATGACTTTTTCTATGTCGGCGGTAGTCCCAGCACTGCCGATCTTCCTGGATCACCTGTCAGCAACAACTTTATGGGCTGCT[T/A]GAAAGAGGTAAGAGATTTGAACAATTGCTCCTCGGAAAAAATCAAATCGTTCCATCCAGAATTATGCCTGTAATTTAATCGCTGTCTGGTTACGCTGTGTTCTGTGTATTCGTTGACTTTTGGGATGATGGAAAGATATGACCTTGCAGTTAATCCTCTGAATGTATTCACTATGATTTCAGGTATATCTAACAAGTTTATTTTTGTATAAATAAATATTTACGGCATATTAATGGCTGCCCAAGTGTATTTAGTGACATTTTTATTTACTATTATTATCATTCTTTTAAACTTTCTTCTATCTGCCAAAATATAACCAAACATCCAAGATCGATTAAGTAGTGGAACATCTTCTTTTATTTACCCATTTCATCTCACATGCTTTGCATACCTAGAGAGATGTACCTTTTTGGGGCTTAAAAAAAATAGTCTGCATGGCTAGGTTTCTAAATATCCTAAAATGTCTGGGATTTTGCTTTGCTTTCACTTTCTAAAGCTGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa4466
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000056256 None None 419 None 6
ENSDART00000088159 None None 449 None 7
ENSDART00000088178 Essential Splice Site 771 1484 10 23
ENSDART00000093094 Essential Splice Site 771 1491 10 22
ENSDART00000111239 Essential Splice Site 768 1488 9 21
Genomic Location (Zv9):
Chromosome 12 (position 26015096)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 24387537
GRCz11 12 24508756
KASP Assay ID:
554-3590.1 (used for ordering genotyping assays)
KASP Sequence:
TCTGAGGCTGGAGCTGGACGGAGGGCGGGTCCGACTCACTGTCAATCTAG[G/A]TACATCTGCCAATAAGAGCGCTCGTATTGATGGTTNNNACCACCACACAGTAG
Long Flanking Sequence:
ATAACAAGCAAAAATACATGTCACAGTTTCTTCATAAACACAGCCTCCCCATAAAAAGAAACATGTTGCATAATAAACATTTTTATGTTATTAATTTGAGCAGTTCTGTTGCTACTGTTGTGCAGTGCTGTAGAAGATTTCAGTGTCTTTCAGTGGTTTTAAAGCATTTTAGTAAACAGTCTTTCATCTGTTGATTTCAACACTGGAGTTTATGATCACAGTCACTGGCCACAATTCTCCTCCTTTAATGTTTGCTAAATTCTTTTTGGTCTCCTTCCTTTCTTGCTGTCTCTCAGATGCCACGATCCTCAGTTACGATGGTAGTAAGTTCATGAAGATCCAGCTGCCGGTGGTGATGCACACAGAAGCGGAGGACGTGTCCCTGCGCTTTCGTTCTCAACGGGCCTACGGTGTTCTAATGGCGACCACATCGCAAAACTCTGCTGATACTCTGAGGCTGGAGCTGGACGGAGGGCGGGTCCGACTCACTGTCAATCTAG[G/A]TACATCTGCCAATAAGAGCGCTCGTATTGATGGTTACCACCACACAGTAGACGTGAAGCATAACATGTTAACACAGCATGGAATTTTTTGTTTTTAATTATTATTATATTTTTTCTCAAATGTGATTTTATATCTATTGTATGGTAATGAATTTTACAATGTAAGATTAGTTTTTGCCAATTTCTGACAAATATTTAGTTGACTACGGGAATATAGACATGTATATAATAAATACTTGACTTTCTATTGTTTTTACATACAGCTCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTTTACATACAATTTTATGTAAATATAAGTTATATATTATTAGAAGTAGTCTGCTAATTTGTTCTACGCTGTAAAAATATACTGACAATAAGTAAAGATCAGGTTTCAACTAAATATTATAAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa641
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000056256 None None 419 None 6
ENSDART00000088159 None None 449 None 7
ENSDART00000088178 Nonsense 1022 1484 15 23
ENSDART00000093094 Nonsense 1022 1491 15 22
ENSDART00000111239 Nonsense 1019 1488 14 21
Genomic Location (Zv9):
Chromosome 12 (position 26044040)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 24416481
GRCz11 12 24537700
KASP Assay ID:
554-0550.1 (used for ordering genotyping assays)
KASP Sequence:
GCATGAATTTTGCTGCCTTTACAGGTGATCTGTATGTTGGAGGTGTGGCT[A/T]AAGATATGTATAAGGACTTGCCAAAGCTGGTGCATTCAAAAGAGGGCTTC
Long Flanking Sequence:
TTAAAAAGTCCTCTTATGCCTACCAAGGCTGAATTTAATTAATACATGGTTTAAATAAGTAAAAAAGTAATTAATTTAAAGGTATTTAAAAATGTAATTTATTACTACTGTAGTGTTTGGAAGTTATTATGTGTTTTGTTTTTCAAATGATATTATTTTTCAAAAGAAATACACATATCATTGCTTGATTAATACGATCAGAAGAAAAATTGTAAGATGATTATTTTTTTTACTGCCAATTTAATGTATATTTGATCAATAAAATAATACCAATTTAAAAAAAATAATAGCTATCCTGAACAAAAACTTGAATTTGTGCAAGATGTTGTGCATGATGTTGTAAACTGTAATAAACAAACGCACCACCAGGGGTCAGTGGTGCACCTTTCTTCCTGTATTTACATAACATGCCCCCTTGGTGGTTAAATTGAAAAGGCACTGTCAGTCAGAGCATGAATTTTGCTGCCTTTACAGGTGATCTGTATGTTGGAGGTGTGGCT[A/T]AAGATATGTATAAGGACTTGCCAAAGCTGGTGCATTCAAAAGAGGGCTTCCAGGGCTGCCTGGCATCTGTGGACCTGAACGGCCGCTTGCCAGACCTGCAGTCAGACGCACTGTCCACCGCCGGCCAGGTGGAGAGAGGCTGCGAAGGTGAGGAAAACGGTATGAATGGCGCATATATACACCGGGTCGGCTTAGCGCGGTCCTTCAGTCTCCAAAGCCCCGTCTCATCTCATGCACACCTGCTCATCCTTTCTGCTTCCTGTTCTCTTCACTATCTGTTTTGTGTTTTCTTCATGCTGGGCCAATTTTAAGCAGTTTTCAGGCTTCTGTCAAGTGTTCTTTTGCCTCTGCTGGAAATAAATATTAGGGATGAATGGGGGTCAAAAAATCTTACGTTTTTTTAAAGATGTAACTTTGAGGAAGCTGAAAATATGAGAGAAAGGAGATTTGTTACTGCCAGTTTGTTAATGCAGTGTAGTGTTTAGTGATTATATTAATTA
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461