Busch Lab

ZMP

slka

Ensembl ID:
ENSDARG00000061525
ZFIN ID:
ZDB-GENE-050411-66
Description:
STE20-like serine/threonine-protein kinase [Source:RefSeq peptide;Acc:NP_001139073]
Human Orthologue:
SLK
Human Description:
STE20-like kinase [Source:HGNC Symbol;Acc:11088]
Mouse Orthologue:
Slk
Mouse Description:
STE20-like kinase (yeast) Gene [Source:MGI Symbol;Acc:MGI:103241]

Alleles

There are 2 alleles of this gene:

Allele Name Consequence Status Availability
sa6301 Nonsense Mutation detected in F1 DNA Not yet available
sa5860 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa6301
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087786 Nonsense 857 1206 12 19
ENSDART00000136177 None None 121 None 3
ENSDART00000142745 Nonsense 852 1201 11 18

The following transcripts of ENSDARG00000061525 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 25026736)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 24672396
GRCz11 13 24802846
KASP Assay ID:
554-5448.1 (used for ordering genotyping assays)
KASP Sequence:
AAAAAGAGGAGCAAAGGGCTCAACAGCAGCTCAGCAATAAACTGCAGCAG[C/T]AGAAAGAGCAACTCTTCAGACGCTTTGAGCAGGAAATGTCGGTCAGCAGC
Long Flanking Sequence:
ATGCGGAGCACTGCATGTATATGTACTGGCCACTGATACACAAGAAATTAACTTTTTCTGATTTTGTCTGAAGTGTAATAACATTCCCGCTTTGTAAAGCAACTTTGTATTGTATTGTTGTGAAAAGCTCTATATAATCAAAATTTAATGGAATTTGTAACTCACAGGACATCAAACGCCAAAAGAAAACCCTGAAAAAGACTCGCAAGTTTTTGGTCGACGGGGTGGAAGTCAGTGTCACCACATCCAAGATTGTCACAGACAATGACACCAAGAGTGAGGAACTGAGATTCCTGAGGTATCTGAAATAACATCAGTTACTCTTTCTAGTCAATTTGCAAATGATGAATTTGATAATGCATGAATAACAATATATATTAGTTGAAAAGTTTATAAAGAGTTATTTGTTGTTCTGTAGGCGCCAAGAGCTACGAGAACTGAGGCTGCTGCAAAAAGAGGAGCAAAGGGCTCAACAGCAGCTCAGCAATAAACTGCAGCAG[C/T]AGAAAGAGCAACTCTTCAGACGCTTTGAGCAGGAAATGTCGGTCAGCAGCCTCATTCCTATACTAGATTTGTTTCCATTCAACATCTTAATCTGCTGTTGACTGTTTAATGTACACTCAGACAAGGCATGATGAAAATTTAAGAGCATAACAAGCAATGTTTGTGTTATGTTAATATTATTTTGCGATTTGTGGATGCACCCAATCAAGTTTTCCTGCTCCAAAATTTGGCTTCTTTGCTAAAGGAACTTTTGATTTTTGAAAATAAGCTCATTCAAGAAGCCCTTTCGAGTTAAACTTTTGAATTTTTTATATTTTTAAAAATTCATTCAGTCTTCAACAGAAAATTTCCCTGATTATTATTTCAGAATAAGAGTATACTTCCCCTAGACATATTGAACAAAAAAATAGCAACCTTTCATTTCTAACCCTTTTTTATACACAAACAAGCACAGAATAATTATCAAAACTCTTTTTTTATTATTTGTTTTGTTTTTGAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa5860
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087786 Nonsense 1117 1206 17 19
ENSDART00000136177 None None 121 None 3
ENSDART00000142745 Nonsense 1112 1201 16 18

The following transcripts of ENSDARG00000061525 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 25009612)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 24655272
GRCz11 13 24785722
KASP Assay ID:
554-3862.1 (used for ordering genotyping assays)
KASP Sequence:
ACCAGATGAGAGACCTGCAGCTGCAGTGCGACTCCAACATCAGAGAACTT[C/T]AGCAGATGCAGGTCTGCAACATTACCTTGTGCTCGCMTGTTTGAGTTCTT
Long Flanking Sequence:
TGAACTAATAGTTCATTATTCTAAAATCCAATATCAATGACAATATTGGTCATTACTTGTCCACAATTTCTTTACACCATTTCCATAGAAAACCCCATTTTCCATTATTTTAGTTTTTAAAAGAATATTCAGGTTTGCATCCTTAATATCTCCATTGCAGCTGCTTTCCAGTGTTCTAGTGTGGGTGAATTCAGCTAAAGTCATTCATGGGTATTATATTTTTTGGCTGTGACCTAAAATATTCTCCACAAATTTGTAAAAAATGGTTTTGGAAAAAAGTCTTTGAAAATTGAGTTTTTAATTTTAAATGCACCCAGTATGTGAAAATAATACACATGATTTGGGAGAGGGTTAATCTTCTGGGGTGTTTTTCACTTTTTCAACAGTTTGCAGTTCAGGAGGACAAGAGACAGAAGAATGAGAGACTTCATCAGCATCAAAAACATGAGAACCAGATGAGAGACCTGCAGCTGCAGTGCGACTCCAACATCAGAGAACTT[C/T]AGCAGATGCAGGTCTGCAACATTACCTTGTGCTCGCATGTTTGAGTTCTTTCCCTCTTCTGTTCTGGCTTATCTTAAATTGCATCATCTGGTTGATTGTCTTGTTGCCATCAGAATGAGAAATGTCACCTGCTGATTGAGCATGAGACTCAGAAGCTGAAGGAGCTTGATGAGGAACACAGTCAGGAGCTAAAAGAATGGAGGGAGAAGCTTCGGCCACGGAAGAAGGTAGAGTAACAACATTATTTACCTTTTCAGTGCATCTAATCAAACCTGATCATTAAATTTGAATGCTGCATTTTCCCCCATGTCATATATTGTGGGTTTCCAGACAAGCTCTTAGAAGGAGAGAAAAAATCTGTCCTGCACACTGTGCTAAGGTAGTGTGAGTGTCAAAGTTCACTCTGGCCACCCTAGTTACAACGCTGTCTGTCTTCTTAGCTCCAGCACTGAGAGCATCAAAATTCGCTACATTGATCTCATATTTAAAGCAGCTGTTGA
Associated Phenotype:
Not determined