Busch Lab

ZMP

slx4

Ensembl ID:
ENSDARG00000061414
ZFIN ID:
ZDB-GENE-050208-359
Description:
Novel protein [Source:UniProtKB/TrEMBL;Acc:Q1MT56]
Human Orthologue:
SLX4
Human Description:
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:23845]
Mouse Orthologue:
Btbd12
Mouse Description:
BTB (POZ) domain containing 12 Gene [Source:MGI Symbol;Acc:MGI:106299]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa45773 Nonsense Mutation detected in F1 DNA Not yet available
sa18364 Nonsense Available for shipment Available now
sa24191 Essential Splice Site Available for shipment Available now
sa29809 Nonsense Mutation detected in F1 DNA Not yet available
sa37533 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

This allele has been removed from public view.

Allele Name:
sa1398
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087576 Essential Splice Site 183 1719 3 13
ENSDART00000105002 None None 116 None 2
ENSDART00000147719 None None 208 None 3

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 22 (position 27426986)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 26942431
GRCz11 22 26804883
KASP Assay ID:
554-1310.1 (used for ordering genotyping assays)
KASP Sequence:
CACACATGAGTTTCACATTTGGCCTCTCTTTCTTCTCTTGGGTTTTTTCA[G/T]ATGTCTTGATGCCAGTGAGAGCAGYGCACCCTCGACATCCCATCATTCCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa45773
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087576 Nonsense 307 1719 4 13
ENSDART00000105002 None None 116 None 2
ENSDART00000147719 None None 208 None 3
Genomic Location (Zv9):
Chromosome 22 (position 27428356)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 26943801
GRCz11 22 26806253
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGGCGCTGGCTCTGTCCCGCTCTCTGCTGGAGCAGGAGGTGGAGAAAAAG[C/T]GAGAGCTGGAGGAGCAGAGGGAAATTCTGGCTCAGATCTCCAGCCCTCCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18364
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087576 Nonsense 411 1719 5 13
ENSDART00000105002 None None 116 None 2
ENSDART00000147719 None None 208 None 3
Genomic Location (Zv9):
Chromosome 22 (position 27429230)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 26944675
GRCz11 22 26807127
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
YTCTTCAACCTCACGCACCCCTCTGGGACAAAAGCGCTCTTCACAGAGGA[C/T]GACAAAACTCTGTTTCAGAGTTCTACACGTCTGAGTTGAGCAGCTTCATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24191
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087576 Essential Splice Site 643 1719 10 13
ENSDART00000105002 None None 116 None 2
ENSDART00000147719 None None 208 None 3
Genomic Location (Zv9):
Chromosome 22 (position 27433945)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 26949390
GRCz11 22 26811842
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTTCTGTGTATAAAATGAGATTGCAGTAGCAAATCTTGTGATAATTTTC[A/G]GGTTTGGTTTAGCTGAGCTACAGCAGCAGTGTGAGGAGTATTCTGGAAGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa29809
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087576 Nonsense 754 1719 10 13
ENSDART00000105002 None None 116 None 2
ENSDART00000147719 None None 208 None 3
Genomic Location (Zv9):
Chromosome 22 (position 27434279)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 26949724
GRCz11 22 26812176
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGATGAGATCTATGAGTTTGCAGCGACACAAAGAAAGACGGAGACAATGT[T/A]GGAAACTGCGACAGAGACTGAGGACGATGAGGGAGATGCAAATACATTCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37533
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087576 Nonsense 1075 1719 10 13
ENSDART00000105002 None None 116 None 2
ENSDART00000147719 None None 208 None 3
Genomic Location (Zv9):
Chromosome 22 (position 27435243)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 26950688
GRCz11 22 26813140
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCTGAAGTTTCCTGGCTGATTCCAGCTACTCCGGTACCATCCACACGATG[T/A]AGCTCTGCCCAGACATGCGTCACTATGCGCCGAACTCAGCTATTCCCCAA
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa5007
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087576 Nonsense 1697 1719 13 13
ENSDART00000105002 None None 116 None 2
ENSDART00000147719 None None 208 None 3
Genomic Location (Zv9):
Chromosome 22 (position 27440966)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 26956411
GRCz11 22 26818863
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTACGTTCAGCACGGCCAAACAAGGCAAGAGCACAACTWCCCGTAGAAAA[C/T]GACGTGTAAAAACCACAACTGCTGGAAGAGGGAGGAAAAAAACRACTAGG
Associated Phenotype:
Not determined