Busch Lab

ZMP

PXN (3 of 3)

Ensembl ID:
ENSDARG00000060766
Description:
paxillin [Source:HGNC Symbol;Acc:9718]
Human Orthologue:
PXN
Human Description:
paxillin [Source:HGNC Symbol;Acc:9718]
Mouse Orthologue:
Pxn
Mouse Description:
paxillin Gene [Source:MGI Symbol;Acc:MGI:108295]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa11930 Essential Splice Site Available for shipment Available now
sa34282 Splice Site, Nonsense Mutation detected in F1 DNA Not yet available
sa328 Nonsense Confirmed mutation in F2 line Not yet available
sa17685 Nonsense Available for shipment Available now
sa17848 Nonsense Available for shipment Available now
sa11924 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa11930
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085993 Essential Splice Site 47 1197 1 14
Genomic Location (Zv9):
Chromosome 8 (position 3681498)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 3430027
GRCz11 8 3488776
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CRGGTGGGACTGAAWACTGGGASRCATTCTGGAATACTCTCTAAACTCTG[T/G]GAGTACTTGTTTTCTGGAAACATTACTGCATTGCGTGTTTGTGGTKAGTT
Long Flanking Sequence:
TTCCTCGAATCAAATATCTTGTTTGTCGCGAGGGGCATGAATGAATTCCCTGAATGAAAGAGCCAAACTGCAGTTAAAGTCCACCATTTAATAATTTGGCAAATAATTCGACTACAGATGTCCATGTAGGTTAAACACCATCACTTTCTCCTGTGTGTGTATTTTGACTGAAACTCGCGCGTGCCCAAATAGACACTCCCACACCCTCCCACTTTAGTTCCTCCGACACTCCCCCCTAAACAGAGCTGGACACGCCCACTTTATTTTGACTTTTTCCAAAGTAGAGGTGTGAAAACACCCTGCTGAAACGAGGGGGTTTCATAGCCCTTTAAAAAATTTTGTCTGTGTAGAAAAGGGTTAATGACTTACGTCTACTGTGTGTTCCTCCCCTTCACACTCTCTCTTTTTCTTTCACACACACTCATACACACACACGTATACACTCACACTCAGGTGGGACTGAATACTGGGACACATTCTGGAATACTCTCTAAACTCTG[T/G]GAGTACTTGTTTTCTGGAAACATTACTGCATTGCGTGTTTGTGGTTAGTTTTGACCCCTGGGTAACTTCTGGAGCGGAATAGCAGCAGACGCGACTTCCTTTCACTGTTAAAAATAGAGCAAACTCAAGAAAGACGCTCTTCTGTTTAAAGAACTAAAACCGAGCTGAGCTTTACAGTTTGGGCTATTTTAATGATGAGTTGTTTCTAATTGCTGGATGATGTGTTTTTTTTTTTTTTTTATATAATAATGCCTTAAATGTTTAGATTGATTCAATTTCAGATGAATTTACTTGTATGTCTTTTGGACTAACTTGCTCTTTTAAATAAAGTTAATCAATCGTAAGCACAAAGCATTTATTATATTAGAGGTCATTTATTACCTTTAATTTTTCTGAACTAAGTACAGGGTTCTTACGGGTGCTGGAAATCCTGGAAAATGCTTGATTTTTAATAGTGTTTTCAAGGTTAGAAAAGTGCTTGGATTTTGAACAAAGTGCTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34282
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Splice Site, Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085993 Splice Site, Nonsense 112 1197 2 14
Genomic Location (Zv9):
Chromosome 8 (position 3693176)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 3440148
GRCz11 8 3498897
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTCAGCTGAAGCCCTGAACGGATCTCTCTCCCCACGGCCGGACTCACAA[C/T]AGGTTCAGCTCAAACTGCACTTTCACAATAAACTTAGATTCATAGTCACT
Long Flanking Sequence:
AGACATGCGGTACAGGTGAATTGGGCAGGCTAAATTGTCCGTAGTGTATGAGTGTGAATAAATGTGTGGATGTTTCCCAAAGATGGGTTGTGGCTGGAAGGGCATCCACTGTGTAAAAACGTGCTGGATAAGTTGGTGGTTCATTCCGCTGTGGCGACCCTGGATTAATAAAGGGACAAAGCCGAAAAGAAAATTAATGAATGAATGAATGAATAATCAACTTGATCATACAAAAATATTTTACCTGAAGTACTATAATCTAAATCTAATTTATCTAAATTACAATGAAGTTTGCTTTCTGCACAGATGCATTGCTTGCAGATCTGGAGTCTTCCACCGCCCATATCTCCAAGTGCCCAGTGTTTCTGCCCGAGGAGACGCCGTACTCGTACCCCAGTGGAGGTCAGCTGTTTCAGGATGACTCTCCTCCTCCACCCCTGCCTCCTCCACCTTCAGCTGAAGCCCTGAACGGATCTCTCTCCCCACGGCCGGACTCACAA[C/T]AGGTTCAGCTCAAACTGCACTTTCACAATAAACTTAGATTCATAGTCACTTAGATTGTACACTGAGCATCGAATAGTCAACTGTCTTGCTAACAAAAATGTTTAATTCATGACTTTGAAAGGTTTTGTACCACATGGACCTAAAGTATTTATTAATTATGGCTCTATTTTAACGGTCTAGGTGCAAAGTCTAAAGCGCATGGTGCAAAAGCATTAAGGGTGTGTTCCTATACACTTTTGCTATTTTAAGGCTGGAAAAATAAGCTCTGCGCCCCGGCGCATGGTCTAACATGGTTGTGCTTAATCTATTAATGAGTTATGGGTGTGTTTTGAGCATAACGTGCATTAAACCAATCAGAGTCTCATTTCACATTCCCTTTAAGACTCAGTTGCACAGCGACATGGTGCATTGTTATATGGCGGGTTTTGTAAGTGTAAAAACTGAACGCTTCACTAGTGAGAAAACAGTTAAACAGAGCATCTGCAGCGTGAGAATAAAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa328
Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085993 Nonsense 261 1197 6 14
Genomic Location (Zv9):
Chromosome 8 (position 3697813)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 3444784
GRCz11 8 3503533
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TATGTTAATTTATGTAAACAGACCCAGCCCATGTGCTTTGACAAGCAATT[T/A]GACTGACGGCCAGTTGGACGCACCTTCCGAGCAGCAGGGCAGAATTTCAG
Long Flanking Sequence:
TCTTTTGCTAACACATCTGATTCAGTTCTTTCCAAAAACAGACATGCAACATGTTCTATATATATAGTGTTCACTGATTCCTACCTCATGCATATGGGAAATTGAATAAAATTAACTTGATTTTTATTTAAAAAAATGCTGCACTATTGATTGCAACATATCCAATCATTACAGAAGTGTGAAGGGTTATTCCATAATCATGTGGTTAGCATGGTAGCCACATCTTGTGCATGGTAGCCATATAATTAAATGATTTCAAACATGAATCATGGCACGATCTCTTGTGATGTCTACTTCATACGGTTGAATGGAACAAACCTCAAAAGAGGTGAGAGAAACGCATAAAAATATGCATAGTGGGGATTATGAGGATCAGTATTGAGAATTGCTGCTCTACAGTTAGGGAACCATGCCTTTGCATTGTGTATTTTAACGGAATGCTGTTTATTTTATGTTAATTTATGTAAACAGACCCAGCCCATGTGCTTTGACAAGCAATT[T/A]GACTGACGGCCAGTTGGACGCACCTTCCGAGCAGCAGGGCAGAATTTCAGCAACCTCTGCCACACGAGAACTTGAGGAGCTCATGGCCTGCCTCTCAGACTTTAAGGTGCAGAGCAATGTGAGTGTGTGTATAGATGCCAGCAACTTGGAATGGCTTTAGTAGGACAGTGTGAGTGAGCTGAAGAGACGTTGTGTCTTGGAATGCGTGCTGAACTATGTTGTTTGGGTGATCTATTTTTATAACTCCTTTACAATCTGGGCTATGTTTCCCAAAAACGCTGTAAGCAGATTGTCGAGACAGTTGGTGCCAATGGTATCTGCAATCTTCTTGGGCTTACAGTGCTGTTGGGAAACTTGCGTGTTTTCATCTGACATTCACAAAATTAACCAGTTTTATTCTTGTAAACTTTTTTGGCTGCTTGTCTATCTCTTTATTTTCATCTCATGATTTCACCATTGTGCCAAGTATCAGTTTCATTTTTCTTTGTTTTTTCCCTTTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17685
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085993 Nonsense 379 1197 7 14
Genomic Location (Zv9):
Chromosome 8 (position 3698665)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 3445636
GRCz11 8 3504385
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AACCAGGGGCTGTGCCTCTACCTTCCAATGGTGTATTTAAGTCTTACTCT[C/T]GACTGTCTCCCCCTCCAGCATCTAGTCCAYGTTTCTCTCCAGCGCCTGAC
Long Flanking Sequence:
AACTTGCGTGTTTTCATCTGACATTCACAAAATTAACCAGTTTTATTCTTGTAAACTTTTTTGGCTGCTTGTCTATCTCTTTATTTTCATCTCATGATTTCACCATTGTGCCAAGTATCAGTTTCATTTTTCTTTGTTTTTTCCCTTTGCTGTTTTGTATATGCTATTGAAGCTTTTTAATTATTTCTCATTCTCTGCATCCCTTAATCTGTCGATCTCTTCTGTTTCTCTTCTTTCTTCCCCTGTCCCTTCCTTATGTCCTCCAGCCAAGTTCTTTAGGCTCCCTGAACTCTGAGCCACTGTTTGAGCAAACTACTACCATTGCTGAAATCCACCCTCCTCCTACGACTACCGTGTCCAAATCCCTGTCCCCTACCTTACCAGCAGAATCTAGGCAATTTTCTCCAGGTCCTTCAAGCTTTGAACTGCACATTGTGGAGGATTCTGGTGAACCAGGGGCTGTGCCTCTACCTTCCAATGGTGTATTTAAGTCTTACTCT[C/T]GACTGTCTCCCCCTCCAGCATCTAGTCCACGTTTCTCTCCAGCGCCTGACTTGGGCTTGGATTCTGCCATTGATGTTTCTGCTTCCCTGCTCTCCTCGGAGGTGGAATCTCTAGTTGTTCTATCTCAGACTATACCCATGACTTCTGCACCTAGAGGTCAGTACCTTTCTCCTGTCAGAGAGGGGAGTCCATCTGCCAAATTGATGAACTCTGGACTGAACTCCTATTCGCCTAACACCAAGTCTCCTAGTCCAAGAAGTTCACCAGCGATTAGCAGAGTCAATGAACGAGTTAGTCCTTTGATGACACCGGCATCTATAGATCTCTATCTCTCCAGACCTGAAACAAAACCTTTGAGCCCAGTGCCATCCCTTCCCAGGTCTCCACTTCCTGCAGTCTCTGAATCATCTTTTCTGTCTCTTCCCAGAGCTCTCTCACCTCCTCCTATCATACCCACTTCCCCAACTCTTGGGGTTTCTAAGTCTCCAAGCCCAAAACAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17848
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085993 Nonsense 1012 1197 11 14
Genomic Location (Zv9):
Chromosome 8 (position 3708142)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 3454720
GRCz11 8 3513469
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGGAGATTGGTTCCAGGAACTTCTTTGMGAGAGAAGGACAGCCATATTGC[G/T]AGAGGGATTATCACCATTWAWTCTCTCCAAGATGCTACTACTGTAACGGA
Long Flanking Sequence:
CCCAGTCATTTTCTTCAATAGTTTGACCAATATCCTTCTCCCAAACATCTTTAAGTTCTAGCCAGGCAGAAGTGCAGTTGTTAGACAAAGTGTCATAAATCCTTGTTATCAATCCTTTTAAACAAGGTGAATTCAGTAAAAGGTATTCAATCTCTGTTGTTTTGGATCTCAGCTCTCCTTTGTCCAACTTTGGTTTTAAAAAATGTCGCAATTGTATTTATAAAAATTGGATTTTGGAACGTTATATTAATCTACAATCTGTTGGAAAGATTTTATGGTGCCTTCTGAAAGTAAGCAAGATATTTGAGAGATGCCCACCATGCTGAAAAAACAGTGTTTTGCAATGTTAAAGGCATATCGGGATTAAAAGTGTGTTTGTTTCTGTACAGGTGGTAACTGCAATGGGGCGCACATGGCATCCTGAGCATTTCGTGTGCACACATTGTCAAGAGGAGATTGGTTCCAGGAACTTCTTTGAGAGAGAAGGACAGCCATATTGC[G/T]AGAGGGATTATCACCATTTATTCTCTCCAAGATGCTACTACTGTAACGGACCCATCCTGGACGTGAGAAGAAACTTCATTAATTTGATACATTTTCATTTGACTAGCATCAAAACCTGATGCCAATCCAGACTATGTGTGGAAAAATCCAGTTTCAGTTTTAGTTTCCTTTATTTATGTCATTCAACACATCACAATAGAATTGTAATGCAGAACGAAATTACGTTGCAACAGACCCAACAAGAACATTAAAAACATCACTCTACAAACAATATAAAATCCTAACATAATAAATAAGCTTTTATATTTCCATAAAAATATAATTATATAAGATATAACCTATTTTAAAAAATCTCTGAAGAGAATTACTTAATAATTAAATACCTATTTCACCATTTGCTGTAATATTAACAATTTATGCTAGTTTAACATATTTATTAACTTATTATTTAACACTAGCTTTCAACAATGCTTAAGAAATGGTATTATTCAAAAGTCTTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa11924
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085993 Nonsense 1018 1197 11 14
Genomic Location (Zv9):
Chromosome 8 (position 3708161)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 3454739
GRCz11 8 3513488
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTTCTTTGMGAGAGAAGGACAGCCATATTGCGAGAGGGATTATCACCATT[T/A]AWTCTCTCCAAGATGCTACTACTGTAACGGACCCATCCTGGAYGTGAGAA
Long Flanking Sequence:
AGTTTGACCAATATCCTTCTCCCAAACATCTTTAAGTTCTAGCCAGGCAGAAGTGCAGTTGTTAGACAAAGTGTCATAAATCCTTGTTATCAATCCTTTTAAACAAGGTGAATTCAGTAAAAGGTATTCAATCTCTGTTGTTTTGGATCTCAGCTCTCCTTTGTCCAACTTTGGTTTTAAAAAATGTCGCAATTGTATTTATAAAAATTGGATTTTGGAACGTTATATTAATCTACAATCTGTTGGAAAGATTTTATGGTGCCTTCTGAAAGTAAGCAAGATATTTGAGAGATGCCCACCATGCTGAAAAAACAGTGTTTTGCAATGTTAAAGGCATATCGGGATTAAAAGTGTGTTTGTTTCTGTACAGGTGGTAACTGCAATGGGGCGCACATGGCATCCTGAGCATTTCGTGTGCACACATTGTCAAGAGGAGATTGGTTCCAGGAACTTCTTTGAGAGAGAAGGACAGCCATATTGCGAGAGGGATTATCACCATT[T/A]ATTCTCTCCAAGATGCTACTACTGTAACGGACCCATCCTGGACGTGAGAAGAAACTTCATTAATTTGATACATTTTCATTTGACTAGCATCAAAACCTGATGCCAATCCAGACTATGTGTGGAAAAATCCAGTTTCAGTTTTAGTTTCCTTTATTTATGTCATTCAACACATCACAATAGAATTGTAATGCAGAACGAAATTACGTTGCAACAGACCCAACAAGAACATTAAAAACATCACTCTACAAACAATATAAAATCCTAACATAATAAATAAGCTTTTATATTTCCATAAAAATATAATTATATAAGATATAACCTATTTTAAAAAATCTCTGAAGAGAATTACTTAATAATTAAATACCTATTTCACCATTTGCTGTAATATTAACAATTTATGCTAGTTTAACATATTTATTAACTTATTATTTAACACTAGCTTTCAACAATGCTTAAGAAATGGTATTATTCAAAAGTCTTATAATGACAGGATAAAACTA
Associated Phenotype:
Not determined