ZMP
mll4b
Ensembl ID:
ZFIN ID:
Description:
Myeloid/lymphoid or mixed-lineage leukemia 4b [Source:UniProtKB/TrEMBL;Acc:A5XBQ6]
Human Orthologue:
AD000671.3
Human Description:
Histone-lysine N-methyltransferase MLL4 [Source:UniProtKB/Swiss-Prot;Acc:Q9UMN6]
Mouse Orthologue:
Wbp7
Mouse Description:
WW domain binding protein 7 Gene [Source:MGI Symbol;Acc:MGI:109565]
Alleles
There are 5 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa35966 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa22705 | Nonsense | Available for shipment | Available now |
| sa22704 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa35966
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000127708 | None | None | 124 | None | 5 |
| ENSDART00000128947 | Nonsense | 644 | 3111 | 3 | 35 |
Genomic Location (Zv9):
Chromosome 15 (position 36221280)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 15 | 37621284 |
| GRCz11 | 15 | 37522869 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGCGGTAGCTCTTGCCAGAGGGTAGAATTACTGCAACAAAAAGACAAAGA[C/T]GAAAACCAAAAGAACGGCCTGTTAAGGCCTGTCCCAACAAGACTGAAGCT
Long Flanking Sequence:
TTCTAGATTCACAGACATTATTTTGCCACATTATTTAAAATATGTGGCTAAGAAATAGCTATTAACTTTTTTTTTTTTTGGTGGGGCCAGTGAAAACTTTGGCAGGGCAAGTAAAAATCTCAACCACTGGCCTGATTGGCCCAGTAGAAAAAATCCTTAGTGTTGAACCCTGCGAGTGTTAAGAAGTGTTAGGAAATGGAATATACATTAGGAAATATATTATAATAAAATAAATTATTTTACATTGAAAAACTTTATTATACTAACATTTTTTTTGATTATACATAATTTTGGTTAAATAAAGAAAGACACATTTTAATACAAATCTCAATGACTCTGATCTGATCTTTTGAATGGTTGTGTATTAGAATTGATCCAGTTGATGCTTTTTTGGATGTAGTTCTAATTGAATTGCTATTAATATTTCTGAATCTGTTTTCACACCTTGTTTGCGGTAGCTCTTGCCAGAGGGTAGAATTACTGCAACAAAAAGACAAAGA[C/T]GAAAACCAAAAGAACGGCCTGTTAAGGCCTGTCCCAACAAGACTGAAGCTACACCAGAGCAGGTATTATCACTTTTTTTTTTCTAAATTTATTGAAGTAAAAATAATTTTCCCATACTAAAGCCAATTCACACCAGTTTTATGCCTGTCGGTATCTGTTAGTGTTAATGTTCTTCAGGATTACCAAAATAAGATTCTGTAATGCTGTAATCAATGCTAAATATGTTCTTTAAGGAGTTGTCTAGGTCAGTAGGTGACTAGGTTGTCACAAATTAAATATATGTACACAGTGTTGGGTAAGTTACTTTAAAAAGTACTTATTACATTTACGTTTAGTAATTTGGCAGATGTTTTTTGTCCAATTGTCCCATTCAGTGATTCAACAAGAGGAGGCAATACACACAATATTTTTCTATGATATTATATATTGTAAATATACCCTGTGCTTATTATGTTTGTGTTTAAGATATGTTATCTAATGTTTATATGTAAATGTATGTA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa22705
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000127708 | None | None | 124 | None | 5 |
| ENSDART00000128947 | Nonsense | 1723 | 3111 | 27 | 35 |
Genomic Location (Zv9):
Chromosome 15 (position 36179912)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 15 | 37579916 |
| GRCz11 | 15 | 37481501 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCCAGGAGCTGCTCCATCCAAACCCCACCACATCTTGACTATTAGTGATT[T/A]GGAAGACACTCGAAGGCCTCGACGGCATAGCCCTCACACCCAAAATAGCG
Long Flanking Sequence:
GCTGTTCAGGAAAAACAAGTGGAAGAGTCGCCCGATCATGGAGAAAATTGCACTATTGCCCACAGTCCATGCCCCCAGTCAGGTAAGTACTACATATCGCTGCTGTCTGCAAGGTGATGATTTAAAATTTTGTGCATTTTTCAGTTTCTCTTTATTTTTTTTATAGAATGTGAAGCCCTTGAATTGGGGTTGTCTTCAACAAATCCTTCCACTGAAGCAAATTTCACCTCAGGGTCTGTCTTTGCCAAACCCGACCTTGGTGCCCGCCCCAAAATCACATCATACCCACAGAACAGAAGACCTGCTGGAGGACTGTCCAGACCACTGCCTTCTCCAGGTAATTGACATTAATTCAGTCAAGTAGTTACACATCACACACACACATAGTTGTCTTCATGATACCGATTTGAACGTTGTTCATTTATTTAGTTTTTTTTGTTTTGTTTTTTTTCCAGGAGCTGCTCCATCCAAACCCCACCACATCTTGACTATTAGTGATT[T/A]GGAAGACACTCGAAGGCCTCGACGGCATAGCCCTCACACCCAAAATAGCGGTACCCGCAGTCACATGACCTCCCCTACCCTTGGCTCCCCTGCAGGCCCAATTCCTTCTAGAGCAGGTGGATCCCACCACCCTAAATCTTCTCAAACTACCTCCCCAATGTTCCCCCTTGGTGCTACTGAAAACCTGTTGACCTCTTCTTCAGCTCGTCCTGTTGGTCGAAGTGCTTCCTCAGTCCGGGGTACTGGAATATTGACGCCCCATTCTACCTCAGGGCTGTTTTCACAGTCCACAAAGCAAGGTGGCATTGGCAGCACCCCTTGCACCAACCGATCCCTCACCTCTCCCACCCATCTTTCCACAAGACCACGCCCTTTTGATTTTAATCCGATAGACTCTTTAGAACTTCCTCACAATTTTATAGCATCACCACAGGAGCATCTATCAGAAACTGGTGCCTTGCCATTAGGAGACGCTTTGAGTATGCCAAAAGTTAATCATT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa22704
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000127708 | None | None | 124 | None | 5 |
| ENSDART00000128947 | Nonsense | 2091 | 3111 | 27 | 35 |
Genomic Location (Zv9):
Chromosome 15 (position 36178809)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 15 | 37578813 |
| GRCz11 | 15 | 37480398 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAATTAATTGTTGTTTTGAGTCAGTTCCCAACTCAGAGGTGCTCACTGAC[C/T]AAGATTCCTTTGGGCTTACTCAAATTTTGGAATCCAGCTCTGGGGTTTGT
Long Flanking Sequence:
TGAATGAAGGCGTAGCTATGAACTGTAGTGCACAAATTGTGGTTGAAGGTGAAGACAACCAAGAGGATTTCTGGGAACCAGATGATAACAAGTCCAAAATGTCCAGCCAGAGACTGTCTTGTACTGTTGATCCTTGTAGGGAGGACTGGGGTAATAGCTCTTCTGATGAGGACATGGAGAACTACTTTAACTTCACTCGCACAGTGGTTACTTGCAAGGCTCAAAGGGATTCATCTAAGAAATCCCCATCTGTAAGGCAGATTTCTCAACTTGATGGTGTAGATGACGGGACTGAGAGTGACACTAGTTTGGCTAATAGTGATAACCATGCTATGAAGCTGTCAAATCAAACCCAGAAACCACACAAGTCGCTCAGCGCTGTACCTCATGAACAGACAGCCAGCAATGGCCTTTGTTTGACTTTTCCAAGTCCTTTATCTGATATTTCATCAATTAATTGTTGTTTTGAGTCAGTTCCCAACTCAGAGGTGCTCACTGAC[C/T]AAGATTCCTTTGGGCTTACTCAAATTTTGGAATCCAGCTCTGGGGTTTGTGGTCCCCAACAAGACACCTTGATTAATTTTGTTGAGTCAAAGTCTTCAAATCCTACATTTTCTACATATGGTAATGATTACCAATCACTTGCTGAGCCAGAGACACCTTTAATTCTTGAAAGATGTGATCCACTTTCTCCCAATGCACATTTCACAGAGCTTGTCCCAGTCCAGGATTCTCCATGTGACCCACAAGAATCTAAAGAACTCTACTTGGATCCTAGTAGTGGCCACTTTGTGTCTTCTGTGGATGATGCTACAGTTTATCAAAACAGCCACTTGCAAGATGATTCCCTAAACTTGAATCAAGTTAATGGGATTCAGTTTTCACTGCAACAAAATCCTGTTCCTTCCACAGAGTTACTTAAACCCGCACCTCTTCTTGAACCTTCATCATCTGTCCAAGTTCCTTTTGTAGCTTTCCCAAATCAGACAACTCCTACAAATGTT
Associated Phenotype:
Not determined