Busch Lab

ZMP

LOC799158

Ensembl ID:
ENSDARG00000060680
Human Orthologue:
PRSS12
Human Description:
protease, serine, 12 (neurotrypsin, motopsin) [Source:HGNC Symbol;Acc:9477]
Mouse Orthologue:
Prss12
Mouse Description:
protease, serine, 12 neurotrypsin (motopsin) Gene [Source:MGI Symbol;Acc:MGI:1100881]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa17777 Nonsense Available for shipment Available now
sa42077 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa35348 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa17777
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085774 Nonsense 158 835 4 14
Genomic Location (Zv9):
Chromosome 12 (position 36173529)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 35048896
GRCz11 12 35149959
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CAGTTTGTGACACACACTGGAMAGATCGTGATGCCAGCGTTGTTTGCCGA[C/T]AGCTTGGATTAGGGTATGAAACTTATGGGYACTTTACTTTAAAGGGGTAA
Long Flanking Sequence:
GTTGATAAGAACAACAATTTTATCTTAATCTGCATCTGATTTTAAAATGAGGCTTCTAAATATACTATTATAAATAGAATATGTAGGAGTCTAACCCAGAGCTATATAGCAAAGTAAAGTGGTTAGTAAAAAATAAAACATTAACTAAAAATGTTATTTACAGCATAAAATGACAGTTGGACAAATTAGCAAAAAGGTGCATTTATGTTCATCTTTTCACATAAGGAGGTTTTAACTTCAGAAAAGATATGAAAACAGTATTTTAATCAAAACATATGAAAATGTTTGACCAGTATTTTCTGTCATCTTCTTTAAAAGAAAGAAATTGCTTCAGACATTGTGTGCTAAATGTCTCTCTCTCTCTCTGTCATTCAGGAGCGGTCAGGCTAGTAGGAGGTTCTTCCTTAAAGAGTGGCCGACTGGAGGTCTACCTGAATGGCCAGTGGGGCTCAGTTTGTGACACACACTGGACAGATCGTGATGCCAGCGTTGTTTGCCGA[C/T]AGCTTGGATTAGGGTATGAAACTTATGGGTACTTTACTTTAAAGGGGTAATTATGTAGAATTCAGAGACTCAGTTCTCTGGCCAGTCAGTATCTGCAGGGCTTACACATCATGTTTATTCATTGGTTGCTTGGAACCAATTAATGCTTGGAACCTCAACCAAAATAAATACAAGGTACCAGTTACTAAACACAGTGGTAACTTCCCCCAAAACTATCCTTACTGAACCATACTAAATGGAAAAGTACCAGCAGATGTTACCTTACTGAATGACCCTTTTAGCAATAAATTTGAGATATTTAACCATTTGTGTCATGTTTCACAAAGTAAAATAGAGACACTGCAGACATCATTTGTATTCAATTATTTCCTTCGGCTTAGTCCCTGATATATCAGGGGTCTCCACAGCATAATGAACCATCAAATACATATGTTTAACAGAGCGGATGCCCTTTCAGCCACAATCCCAGCATCATGCTGGGAAACACACATACACTTTCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42077
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085774 Essential Splice Site 271 835 6 14
Genomic Location (Zv9):
Chromosome 12 (position 36156142)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 35066283
GRCz11 12 35167346
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTGGGATGACATGGACGCTGAGGTGGTCTGCAGGCAACTCGGACTGGGG[T/C]GAGTCCAGTCTACTGCTCATACATCAAATGCTGACCCCACACACCCCTGT
Long Flanking Sequence:
TATATTATGTTATTATAAGGCTTTTAAATAGGTAATTGTAATTATAAATTTACTGTTAATAAATATAATTTATTCCTATGATGCAGAGCTCAATTTTCAGCAACTATTACTTTTCTTTTTTCCACCATTTAATAAGCATATTTTGCTATTCCAACTATGCATAATTATTATGTTTATTTTTATTTAGTTTCATTTTTTCCTTCTCATCTTTGTCCATATTAGACCTTTGACTCATTAAGAACTGCAAGGTTATTGCAGAGAGAGAGTTCTTCATGCAGAGCATTGTGGGAGTCACTCTGTTTATTGATGTGTTTGTGGCTTTGGGTCATGATTTCTGGTTTGCTCTCTCAGGTAATGGCCCGCCGCTGCGGTTGGTTGGTGGGGAGGAGGACTTTGAGGGACGTGTAGAGGTCTTCCATGATGGACGCTGGGGGACCATTTGTGATGATCAGTGGGATGACATGGACGCTGAGGTGGTCTGCAGGCAACTCGGACTGGGG[T/C]GAGTCCAGTCTACTGCTCATACATCAAATGCTGACCCCACACACCCCTGTATATGACATATAGTGGAGGATTTCACAGAGACACAGGGTTGTAAATTATAATGAGTGTGAAAATTGACCGTGGCAGGTATCGCATATCAACACACTAGCCAATTTGGCAGTTTATGATTCATAAAATTATGAATGCATGTAATCATTATCAGAGCCCTCCCTCTAAAGAGAACCCTCAAAGATGAGCAAAACAAACAGTTAAAAATGGCATGCCAGCTTTGAACCTGGATATACCCACTCAGATTAGGATCAACGGATTGCTGGACTGGAATTCAAAAGGTTTGTCTGACTTTTCAGGGATGTTTACTTCTGAAATTGTGAAATCATTTGAACAAATTAGAGCAGAGTTTGATATTTCCTTTAAAGACTTTTTTAAAAATATTCTCAAATTTGTCATTTTATAGAGTGCCTATTAAAGCAAAAACAAATTTGATTTTAAATTATCGGAAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35348
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085774 Nonsense 743 835 14 14
Genomic Location (Zv9):
Chromosome 12 (position 36128967)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 35093458
GRCz11 12 35194521
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAGCATCCCAGCACACTTCTTCAGGCCTGGGTTCCTCTCCTGCCCTCGTG[G/A]CAGTGTAAGAAACGTTACGGCGAGCGTTTCACCAGCCACGACATGTTGTG
Long Flanking Sequence:
GCAGTCATACACAATATTAATTCTTTTTCCACTAACTTTATATTCTACACTGTACATTATTTCTGTTAAGTGACCAGACTTTTGTCTAAGCAAGTCAGACCTTACTGTCCTAATTAAATAAATAAAAAATGAAGGCATGATCATATTTTATTTGGGTAAAATAAGCGTAATCTAGAGGCCTTTGCCTTTCATACTGTATAAGCTATATTTGATACCAAGTAATCAATTAGAAGTCAATTTGTTGTTCCTAAAATCTTGGATAGGCAACAAGACTTTTGTCAGGTAGAGGTACAGTAAAAAGGATACTTTAGCCCTAAAAGAAAGCTGTCTTTTATTGTGTATACAATTTATTTTTTTGCGTTCAACAGAAGAACATGAGTGCCAGAAATGCCATATTTGAGTTGAAATTGGTATTTTATATTTTGTTTTCCCTTTGTTTCTCCAGACACTGAGCATCCCAGCACACTTCTTCAGGCCTGGGTTCCTCTCCTGCCCTCGTG[G/A]CAGTGTAAGAAACGTTACGGCGAGCGTTTCACCAGCCACGACATGTTGTGTGCGGGCAGCATGACCTCTGACCTCAGAAAGCATGCCGACAGCTGCCAGGGGGACAGTGGGGGTCCGCTGGTGTGCCAAGGCGAGGCGGGCCGCTGGGTACTGACAGGGGTCATCTCCTGGGGTCACGGCTGTGGCGACCCCTCATACCCGGGTGTGTATTCACGGGTCAGCCGCTACCTGGGCTGGATTGAACAGGTGACGCACAGCACTGCACCGCTCCAGCACTGAAGCACCTTTCGCTCCCAAAAGCACAGGACTTGCTGAAAGGAAAAATAAGAGCCTGAGAGTGTTCGACACCTGCTGTATGCTTTCAACACCCTGGATCTTAATTCCTAGCTGTACGATTCAATTTCATGTCTTTAGCATTTAGAGATTAGGGTCTTTCCTTACACACAGACTTAAAGCTGAAGTATACTTTGGTTTTTTATGTGTATGTCAAAGGTCATGAG
Associated Phenotype:
Not determined