Busch Lab

ZMP

kdm1a

Ensembl ID:
ENSDARG00000060679
ZFIN ID:
ZDB-GENE-030131-7828
Description:
Aof2 protein [Source:UniProtKB/TrEMBL;Acc:A0JMQ3]
Human Orthologue:
KDM1A
Human Description:
lysine (K)-specific demethylase 1A [Source:HGNC Symbol;Acc:29079]
Mouse Orthologue:
Kdm1a
Mouse Description:
lysine (K)-specific demethylase 1A Gene [Source:MGI Symbol;Acc:MGI:1196256]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa42949 Nonsense Mutation detected in F1 DNA Not yet available
sa36433 Nonsense Available for shipment Available now
sa23095 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa42949
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085758 Nonsense 412 848 11 21
Genomic Location (Zv9):
Chromosome 17 (position 28154664)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 28078591
GRCz11 17 28095554
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCTTAACAACAAACCTGTGTCTCTGGGACAAGCACTGGAAGTGGTCATA[C/T]AGTGAGTAAACTCTGTTTGCCTCATGTTCTGTCACTGAACATTTGTAAAC
Long Flanking Sequence:
ATTTTTTTCTTCTTCATTAGAACCTTAAACATTTAATTATGTTTATACAATTCAAGTAAACAACTGCTGGCATGTTCAAACTCAACAATTAATACAGGAATGTCAAAATTAATACATGTGGCTCCTGACAATACTTTGAGTTTATAAAGAGAATCAGTCTGTGCAAGAAACTGAACTTTATTTGTAATATTACTTTTAATCCTTTTACTTTAAATACTTTTAATTTAGCTTTGTAAGACCTCTGTGTATCACCAGGAAACAGCAAAGATTATGGTTTCAGCTACAGATTTATAATATACTACTGTAGAAAAAAAAAACTATTATCAAGTGCTTATTTAATGTTTGTAACTTTGCCAAAGGTCCCTAAAGAGAAGGATGAGATGGTAGAGCAAGAGTTTAATCGCCTGTTAGAGGCAACATCATACCTCAGCCACCAGCTTGACTTCAACTTTCTTAACAACAAACCTGTGTCTCTGGGACAAGCACTGGAAGTGGTCATA[C/T]AGTGAGTAAACTCTGTTTGCCTCATGTTCTGTCACTGAACATTTGTAAACATGCCTCTGAGTAAAAGCAAATTCTGACGTTTAGACTTTTTATTAAAATAGAGTAGCGATGTGTTGTTGAAGTGCTCCTCTTCTGTATTCAGGCTACAGGAAAAACATGTGAAAGATGAACAGATCGAACACTGGAAGAAGATTGTGAAGACTCAAGAAGAGCTCAAAGACCTACTGAACAAGGTAATTGACACATCCTTCATTAACAGCTTACTCATGGCACACAGTTACTTAGATTGTGTTTTTCTGTCCAGATGGTGACTACTAAGGAGAAAGTGAAGGAGCTTCATCAGCAGTACAAAGAGGCCAGTGAAGTAAAGCCACCCAGAGACATCACAGCTGAGTTCCTGGTGAAGAGCAAACACAGAGACCTCACAGCACTCTGCAAGGTAGAGAACCAATTTCCCACTTTGACCAAACCCACATGACCTCACCCCACATTGACCATAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36433
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085758 Nonsense 627 848 17 21
Genomic Location (Zv9):
Chromosome 17 (position 28149976)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 28073903
GRCz11 17 28090866
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTATAAATGTGACGCCGTGTTGTGTACCCTACCTTTGGGAGTGATGAAA[C/T]AGCAGCCGCCGGCCGTGCAGTTTGTCCCTCCTCTGCCAGAATGGAAGACG
Long Flanking Sequence:
TCTAAAGTACCTGTACTGGGACAAAAAATAAATATATATTTACAGACCTTCACATAAGTAAATAAACAGATTGAGTTATGGGCTCAAAAATCTGCAGAAATATGTGAAGATGAGCATAGTCATAGGTTTGATTTACAGTGTAAACTCAAATTACAGAAAAAAGTGTTTGCTCCATCTGTGTTTGAACAGGATGATGATTTTGAGTTTACGGGCAGTCATCTGACTGTGCGGAACGGGTACTCGTGTGTCCCGGTGGCCCTTGCCGAGGGTTTGGATATCAAACTCAACACTGCAGTAAGACAGGTCCGATACACATCATCTGGTGAGTCAGTCATTCACTCAAGTTCCTGTTTTGTCTGTGTTGTGTTTGTGTTCATGACCATCATGTCCTTCCTGTCTCAGGTTGCGAGGTGATTGCGGTGAATACTCGCTCCACTACCCAGACATTCATTTATAAATGTGACGCCGTGTTGTGTACCCTACCTTTGGGAGTGATGAAA[C/T]AGCAGCCGCCGGCCGTGCAGTTTGTCCCTCCTCTGCCAGAATGGAAGACGGCTGCCATCCAGAGAATGGGCTTTGGAAATCTCAACAAGGTGTGAATAACTGTTTATTCCATTGCAGACGAGAGAGTGTTGATGTAATGACAATGCTGGTCTGCGTCAGCTTGGGACATTTTATGAGAATATCAATCCAGAGTGAACATTTGCTTGGGCTGGTTAGGTCAAATCAAATCTAAAGGGATGGATATTGGTATCTTTCTATATATAGTCCTTAACAAATTTACCCCTACGTATATTGAGAGTTCAGGATGCGTCATCATCATTTTCCTCCTCTGCACTCTCTCGCTCTCCTCGCTCCCTCTCCTGGTTCAGCTGCAGCAGAAAATTGCTGCAGTATTATGCAATTGTCCTGCTCCATTTCTCTGGTTTTGTCACAAGAGGGCACAGTGTGGTACTAGATTCATTCACAGGGCTGCTTTATCAGAACCAGCTGTCTGCACACAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23095
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085758 Essential Splice Site 737 848 19 21
Genomic Location (Zv9):
Chromosome 17 (position 28146512)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 28070439
GRCz11 17 28087402
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTTGTCTGGCCATCCTCAAGGGCATTTTTGGAAGCAGCGCAGTCCCTCAG[G/A]TGAGCTCGGAGGCGCTTGCTTCATTTTTAGCTCTGTGCTTTTACAAATAT
Long Flanking Sequence:
TAGTAACCTCATCTGAATCGCAACATTTCCAATATATGGCATTGATTTTCAATGGAAAGTGAACAAAATGTCATTTAAGCTTCGTATGTACAACAATTTAAGTCAGAATTGGTATTTTAGGTCTATGCTCAGAAGCCTGGGCTGATTATACAAATTATAAAGTATAATTAAATTATAGTGTTTAAAGTGTTACACAATTACAATAAAGAAAATCTGAATGTAATAACGGGCAGGTATGAGCTTGCACCTTAACCATAACCAGTAAATGTCATAAAAATGCAAGTTGAAAAAAAGCTATGTGATATGTGAATTATTGTTGCATAATTATGCCACTTAGAACTCGCTTTGAATCTGACCTTTGCATCTTCACAGCCCCCATACTGTTAGCTCTGATGGCAGGAGAGGCTGCAGGCATTATGGAGAATATCAGCGATGATGTCATCGTTGGTCGTTGTCTGGCCATCCTCAAGGGCATTTTTGGAAGCAGCGCAGTCCCTCAG[G/A]TGAGCTCGGAGGCGCTTGCTTCATTTTTAGCTCTGTGCTTTTACAAATATTTTTGTGAACAGCTAGGGATACATGATATTGGATAAATATGATATTCCAAAGTTTTATTGTTTTAGCAATGTATATGGCGATATGAATACAGTTTAACAAGATGGTTTGAATAGAAAAATTGTATAATCACAATGCAAAAAAAAATGTCTTTGTCTTTTTTCTAGTTCAAATATCTAAAAAAAAAGTTTTTGTAAGTAATAAGTTAAAATGAAGAGCTTTTCTTAAAACAAGCTAAATTATCAACAATCTTATTTTCACTTTAAAATGTAGATATTTGGACTAGAAAAAGACAAAATTATAAGTTAGAAAAACTTTTTGTTTTGCATAAATCCTATAAATAAACATAATACATGTTTTTTACACCTGCAAACATCTTATTTTTTGTCCAAATGTGTTAAACTCTTGAAATGTTCAGTCACCGGCCTTAAACACATGCAAATAATACATTT
Associated Phenotype:
Not determined