Busch Lab

ZMP

A7YYF5_DANRE

Ensembl ID:
ENSDARG00000060532
Description:
Zgc:173905 protein [Source:UniProtKB/TrEMBL;Acc:A7YYF5]
Human Orthologue:
ADAM22
Human Description:
ADAM metallopeptidase domain 22 [Source:HGNC Symbol;Acc:201]
Mouse Orthologue:
Adam22
Mouse Description:
a disintegrin and metallopeptidase domain 22 Gene [Source:MGI Symbol;Acc:MGI:1340046]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa6446 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa14978 Nonsense Available for shipment Available now
sa19148 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa36238 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

This allele has been removed from public view.

Allele Name:
sa28730
Status:
Less stringent filtering
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085376 None None 237 None 9
ENSDART00000125590 Essential Splice Site 33 918 1 31
Genomic Location (Zv9):
Chromosome 16 (position 45996171)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 43249464
GRCz11 16 43153222
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTCTTCATGAGCTCTGTGGTACATACCAGCATGTCTTTGGCTCATTACGG[T/C]AAGGGTGTATTTCTGATGTATTTCACCTCGATGACAAATAATTAGATTGT
Long Flanking Sequence:
ATTCTGTTTGGCGCAGAAGGTGACAGCAGGTGGAGCGAGCTCACACTACACTACCCGTCATCCCGCGTGCACAGCTCGCTCATGTATATTTATGAGGCGTTTCTGCAGTGAGGCGGCTGGATATTATTGATGTCTCGCTGAGGAGGTGGTGGCTTGTGCTCGGCGGAGAAAAAAAGGGCCTGAATTTAGTTTTCCAGAACGACTAGTCATCCGCCCGCCGCTCGCGCAACCCGCGTCTCGATGCAGAGGCTGCTCGCGCTCGCGTCACTAATGGCAACCAGCGCGCGCCAGGATGCGTGTGCCTTTATGAGGGAGACCGAACATCGCGTCTAACTTGGGATTTAACGCGTATATCGAAAATAATTGGGATACATGTGATTAAATGCGATTTTTCTGAATCGAATGGATGCGGGAACGATGCCTCTCCGTGTGGGGATTTCCTTACTGTGCCTCTTCATGAGCTCTGTGGTACATACCAGCATGTCTTTGGCTCATTACGG[T/C]AAGGGTGTATTTCTGATGTATTTCACCTCGATGACAAATAATTAGATTGTATTTTTTAAGAGTATTAGCAATGGAGCATCCATTTCAGGTCATGTAAACAATTGGGAAATGTATATAGCGTTAAATAAACGACCCCAACGCGCAGTTTATCTTACCAAAACTAATTAATATGTATTATTTCATACGTTTATTTATTAAGAAGGGAATATTTACTTGGTAAAAACAGGCCATCGTGTTTTTATGCTTCCAGGAGACGCCTTGGTAAAGACGAGGGCTCGGCGTGATGACGCCAGGTACCTCGGGAAAGAGAACACCGTACCAGTCCGGTTAGTCTACCAAATGGACGGAGACCGTCAGACCGCTCATGATGCTGTGAACACACGGATCCGAATGAGATCTGACAGTAAACAGGTGTGTGTTTTTCATCTCATGTTCGGATGTCATCAATGTGTGTGTCAGGGATGCTCTCTCGCCTCCCGTTGCCATTGGAGACGCGCTGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6446
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085376 Essential Splice Site 35 237 3 9
ENSDART00000125590 Essential Splice Site 206 918 8 31
Genomic Location (Zv9):
Chromosome 16 (position 46077742)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 43331035
GRCz11 16 43234793
KASP Assay ID:
554-5073.1 (used for ordering genotyping assays)
KASP Sequence:
CACACACACTATATTCAGTTCTCCTTACTAATATTTTAGNTTTTTTTTTAC[A/T]GTTCATCTGGCAGAGTCACTTTTTGAAAACCCTCCATTGTTCAGTGCCGC
Long Flanking Sequence:
TAATTTACTTAATCATTGTAAGGCAGTGTGTATTAATTTTCTTTAAGTAAAGTCAACTAATCACATTTTACTGTGTACACAAAAATAGTTTTTGCTGCATGTTCAAACTACATATTTAAAATGAGCTAAAAGGCACAATTCTTGAGATTCTTTTGAGACAATATAATTGTTTTATGTTTGATCCACTTAAAATTATTAACTTAATCAATTTGTATTGGGACAACATGAATGAATTGGATGGAACCCTTCATTTTTTTTTTACAGTTTACAATGCTAAACACTGAACGACAGTTACTAAATTATAAATTAATAAATAAAACTATTTTAAAATATGTATTTTAATTATAGGTATGCTTAAATTATGGTAAGTCCAGCCCTGCAAGTATACACTACAATTCAGGCCCCATGAGTGGTAAATAATAGTGCAGAATGAGTCGGTTTTATTTTGCGCACACACACTATATTCAGTTCTCCTTACTAATATTTTAGTTTTTTTTTAC[A/T]GTTCATCTGGCAGAGTCACTTTTTGAAAACCCTCCATTGTTCAGTGCCGCCCACCGGAGAAAAAAGAGACAGGTGTGTGTGTATACAGTCTTAAAACAATCATAGCTCATGGTATGCACATGTATCTGTTAAGTTTTGACTATGAGACGGGATTGCAGTGCTGCTGTAAGTGCTACTCCAGATCTCTGTTTCTTCTGTGTCTTTCTTTTCCTCTCCATCTCCCCTCTTCTCATGAAATATTTAGAGCAGTGCTGTGGACACTTTATGGCACTAATGTATAGATCAGCTTTTTCCTCTGCAGTAAGCATGTTATGCATGCCGCAGCATGATATGAAACATATTCATCACTAGGTTTGGTTCTAAATTAGAATGATCGCTGTTCCAGATAATATAAGAATACAATTAGGTGATATTCAGTTCTGTCTCTCTGAAGCATCTGCAGTCTTTTAATGATGTTTGACAGAATGCTATAATCAAATTAAAATAAAATGTGTGGTAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14978
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085376 None None 237 None 9
ENSDART00000125590 Nonsense 478 918 17 31
Genomic Location (Zv9):
Chromosome 16 (position 46099566)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 43352859
GRCz11 16 43256617
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTTKTTCTGCAGGAGTGTGCTAAAGAGGGGGAAAACTGCTGCAAAAAATG[T/A]ATGTTGACTCAGGGAGCCAAATGCAGTGATGGTCTCTGTTGTAAAAACTG
Long Flanking Sequence:
GGGTTGCAGTTGGAAGGGCATCCGCTGCGTAAAACTTATGGCGGAATAGTTGGTGGTTCATTCCGCTGTGGTGACCCCTGATAAATAAGGGACTAAGCCAAAGGAAAATGAATGAATGAATGAAAACGGTTACTGTTAACTATAATATTTCATTTGAAATTTTGTCGATTTTGTTAAAAGAAATTGCTAAATTATTTTCATTTTAAATCCATATGAAAATAAACAATACATGTGACAAATATTAGGACACTAAATGTAAAATGCAAAGTAACTGTGTTCTTTACTTCACGTTTTTGTTTTCGTTTGCAGCTCTTGGATCCTCCAGAGTGTGGAAATGGCTTTGTGGAGGCAGGAGAGGAGTGTGACTGTGGAAGCCCAGCCGTGAGTGATCTTCCATCAACATCACGATCACATTAATCTGACACTGCTTATGTAATCTCTTTTTTTCCTCTTGTTCTGCAGGAGTGTGCTAAAGAGGGGGAAAACTGCTGCAAAAAATG[T/A]ATGTTGACTCAGGGAGCCAAATGCAGTGATGGTCTCTGTTGTAAAAACTGCCAGGTAGGTGCTGAGTCATACAAGAAAGAAAAAAAAAAGTGCAGCTGTTTCTGTTTGAGTGAGATTTTTAATGATCATTGTGCTGTCTCTGTAGCTGGAGTTTATGGGTGTGCTTTGTCGAGAGGCTGTCAATGATTGCGACATACCGGAAATGTGCACTGGGAACTCCAGCCAGGTGAGGGCACTGTTGTGCACATCTCACAACACATCCAGCAGGAGCAGAATGGGTTATCTGCTTGTTATATTGTGTATCCACATAAGTTGTGACATATGGAATAGTGTTTCCAGGTCCAAGCCGTTACTCAGTTGAATATGCTATATGCACAGCCAGTGTTTTTTCCCCTACAGATAAACCAGGCCCGGCCCTAACCAATTTGGCGCCCTAGGCAAGATTTCAGGTGGCGCCCCGTCACATCGCAGTAAATTCCACTGCTAGTGTACAGTCATAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19148
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085376 None None 237 None 9
ENSDART00000125590 Essential Splice Site 496 918 17 31
Genomic Location (Zv9):
Chromosome 16 (position 46099621)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 43352914
GRCz11 16 43256672
KASP Assay ID:
2261-0225.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGACTCAGGGAGCCAAATGCAGTGATGGTCTCTGTTGTAAAAACTGCCAG[G/A]TAGGTGCTGAGTCATACAAGAAAGAAAAAAAAAAGTGCAGCTGTTTCTGT
Long Flanking Sequence:
GTTCATTCCGCTGTGGTGACCCCTGATAAATAAGGGACTAAGCCAAAGGAAAATGAATGAATGAATGAAAACGGTTACTGTTAACTATAATATTTCATTTGAAATTTTGTCGATTTTGTTAAAAGAAATTGCTAAATTATTTTCATTTTAAATCCATATGAAAATAAACAATACATGTGACAAATATTAGGACACTAAATGTAAAATGCAAAGTAACTGTGTTCTTTACTTCACGTTTTTGTTTTCGTTTGCAGCTCTTGGATCCTCCAGAGTGTGGAAATGGCTTTGTGGAGGCAGGAGAGGAGTGTGACTGTGGAAGCCCAGCCGTGAGTGATCTTCCATCAACATCACGATCACATTAATCTGACACTGCTTATGTAATCTCTTTTTTTCCTCTTGTTCTGCAGGAGTGTGCTAAAGAGGGGGAAAACTGCTGCAAAAAATGTATGTTGACTCAGGGAGCCAAATGCAGTGATGGTCTCTGTTGTAAAAACTGCCAG[G/A]TAGGTGCTGAGTCATACAAGAAAGAAAAAAAAAAGTGCAGCTGTTTCTGTTTGAGTGAGATTTTTAATGATCATTGTGCTGTCTCTGTAGCTGGAGTTTATGGGTGTGCTTTGTCGAGAGGCTGTCAATGATTGCGACATACCGGAAATGTGCACTGGGAACTCCAGCCAGGTGAGGGCACTGTTGTGCACATCTCACAACACATCCAGCAGGAGCAGAATGGGTTATCTGCTTGTTATATTGTGTATCCACATAAGTTGTGACATATGGAATAGTGTTTCCAGGTCCAAGCCGTTACTCAGTTGAATATGCTATATGCACAGCCAGTGTTTTTTCCCCTACAGATAAACCAGGCCCGGCCCTAACCAATTTGGCGCCCTAGGCAAGATTTCAGGTGGCGCCCCGTCACATCGCAGTAAATTCCACTGCTAGTGTACAGTCATAAGAAACAAAACAGCTTTTTGATCGACTACTACAAGCTGGGAAAATGTCAGATAAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36238
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085376 None None 237 None 9
ENSDART00000125590 Essential Splice Site 637 918 22 31
Genomic Location (Zv9):
Chromosome 16 (position 46104724)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 43358017
GRCz11 16 43261775
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGATTGACCTCTTTCTCTGTGGCCCAGCACAGCGCTTCACTGGATTGCAG[G/A]TACACACGCACGCACACACACACACACACACACACACACACACACACACA
Long Flanking Sequence:
TTCATTCATTCATTAATTCATTTTCTTTTCAGCTTAGTCCCTTTATTAAGCTGGGGTCACCAAAGAATTAGTTAAAAATTTATTTTGATTTCAGAAATAATGAGTAAAAATAAAGTCAGTTTTTCTATGAAAAAAGCAAATCAATTTGCCAAAGAGTTAATCAAAATAATCTTGTTTTTGCTTTGAAATAAGGAAAAAGTCACTTAATTTTGTTACACACTTAACATATTAGTTCTGAGAACAAGACAATATTTACTTTAAATATTTATACTAGAAACTCAAGAAAGGCTTTTTTTTCGCAGTATTGATGAGATGTCTGGTCTGTGGCGGGGAAAGATATTTAAAAGTGTGTGTGTGTGTGCGTGTGTGTCTGTTTTCAGGGATGTTCACTGTGGATACCTGCTGTGCTCCAACATTTCTCCAGCACCTAGACTAGGAGAGTTACAGGGAGGATTGACCTCTTTCTCTGTGGCCCAGCACAGCGCTTCACTGGATTGCAG[G/A]TACACACGCACGCACACACACACACACACACACACACACACACACACACACACACACACACACTATTTCTTCAGCTTTCTGTGTGTACTTTGATTTTTCTGAATGGAGTGTGAATGTTTCAGTGGAGGGCATGTGCTGATTGATGGTGACACTGATCTGGGATATGTGGAGGACGGGACGGCTTGCGGGACGGATCGCATCTGCTTTAATCACAAATGCCTCCCAGTGCAGGACTTCAACTTCAGCACGTGTCCCGGCACCAATGAAAGAGTGATCTGCTCAGGACATGGGGTGAGAGGTTGTGTGTGGGGTGTGAACTGGGACTGTTTTTTCACCCGTTGATCTAATTTCAGCTTCAGTGCTAAGTGCCATGAGAAAATTTGCTGGATATGTATGCACAATATATATATTTTAAATGGTAAAATTCTATATATTTTTATTAGAAAACTATATGTCTAATAGTACTAATACACTCACCAGCCACTTTATTTGGTACACCT
Associated Phenotype:
Not determined