Busch Lab

ZMP

kcnq3

Ensembl ID:
ENSDARG00000060085
ZFIN ID:
ZDB-GENE-070912-301
Description:
Si:ch211-66b9.3 protein [Source:UniProtKB/TrEMBL;Acc:A7MBT2]
Human Orthologue:
KCNQ3
Human Description:
potassium voltage-gated channel, KQT-like subfamily, member 3 [Source:HGNC Symbol;Acc:6297]
Mouse Orthologue:
Kcnq3
Mouse Description:
potassium voltage-gated channel, subfamily Q, member 3 Gene [Source:MGI Symbol;Acc:MGI:1336181]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa531 Nonsense F2 line generated Not yet available
sa33002 Nonsense Mutation detected in F1 DNA Not yet available
sa44545 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa531
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000084303 Nonsense 169 401 4 11
ENSDART00000136141 None None 395 None 6
ENSDART00000145494 Nonsense 169 391 4 9
Genomic Location (Zv9):
Chromosome 2 (position 43132780)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 43182244
GRCz11 2 43031662
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCTGCTGCTGTCGATATAAAGGCTGGAGAGGACGGCTCAAATTCGCCCGC[A/T]AACCGCTGTGTGTCCTGGGTGAGTTCAACACACCGACCCAAACAAACACA
Long Flanking Sequence:
TCGAGCTGAAACTAGCAAACAACAATTGCGTTGCGTCTTGCGCCGCAATGCGCCAGGTGTATGACAGGGCCCTATATCTAAAAATGACTAAAAATGGAGTTATCTGTGATTGCAAAAATCCATTTTATATATATCATGCTTCTGTATAATCTTTGTCGGAAGTGTATTAGGATATTAAGATATGAGTATTTGGTCAAAGATCACAATCCCTGTTTGTTATTCTCTAGGTTTCTGATTGTTTTGGGATGTCTGATTCTGTCGATATTAACAACATTCAAAGAGCACGAGAAGGATTCGGCTCACTGGCTGGTGATTCTGGTGAGTGTATGTGTATTCTGTACTTGTGTATGTGTGTTGAGAAGAAAATGACTGACTGTTTCTCTCACCTGTAGGAGACGTTTACCATCTTTATTTTTGGAGGTGAGTTTGCGTTGAGGATATGGGCCGCCGGCTGCTGCTGTCGATATAAAGGCTGGAGAGGACGGCTCAAATTCGCCCGC[A/T]AACCGCTGTGTGTCCTGGGTGAGTTCAACACACCGACCCAAACAAACACACACTCTCACTTAAACACAAACACACATATGCATATACTGTCACAGTGTCTTTAATTAAACATCAGCAAGGAGCAAATCAGGACACACACTAACAGAAGATATGGACTTACAAGCAATAGAAGCAAGCAGGCATTATGCTGTAAAAATATTTTGTGATTCATGGTTCTTTTCGGTTTATTTGCACTTTTGATTTGCATTATGAGACCTTTGACTGGATGCAGTTTACACTAACCTACTTGCTTACTGTTTAGTCAGAAGATGGCAGCAAAAAGTTAAGAGCAGTGGCTTGACCCTCCTAAATTATTAGCCCCCCTGTATATTTTTCCAAAATGTTAGTTTAACGGAAAGAAGATTTTTTTCATCACTAATTACTAATATTTGTTTTTTATTATTGCCATGATGAGAGTGCATCATATTTTATTAGATATTTTTCAAGATATTACACTGGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33002
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000084303 Nonsense 238 401 6 11
ENSDART00000136141 None None 395 None 6
ENSDART00000145494 Nonsense 238 391 6 9
Genomic Location (Zv9):
Chromosome 2 (position 43128693)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 43178157
GRCz11 2 43027575
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGCAGACAAACTCAACTGTGTGCGTTTTTTAGGAGCTGATCACAGCGTG[G/A]TACATCGGCTTCCTGTCATTGATCCTGGCTTCTTTCCTGGTGTATCTGGT
Long Flanking Sequence:
ATTTTGTATGTTCTCAGATATTTTTGTTCTGATCGCTTCGGTGCCGGTGGTTGCCGTACGTAATCAGGGAAATGTGTTGGCCACGTCGCTGCGCAGTCTGCGTTTCCTGCAGATCCTCCGGATGCTGCGAATGGACAGACGCGGAGGAACCTGGAAACTGCTGGGATCTGCAATATACACACACAGCAAGGTATCCGAATGTGATGTGATGTACACAAACAGTCCGTAGCCCCCGATCAACATCGGAACGATTGTCCTGTTTGTTTGAATCATGTCATAGAAACTGATGGGGTCGGCAGTATACAAACAGTAAACAACGTAAACACACACTCACATCTTTTAAATCTGCTATAAACACACACACACATACACACACACACATACAGGGGAAAGTACATACGCAAGCACAAACAATCCTGTATCAGTGTCTGGTGATGTTTGATCTCCTGGCTGCAGACAAACTCAACTGTGTGCGTTTTTTAGGAGCTGATCACAGCGTG[G/A]TACATCGGCTTCCTGTCATTGATCCTGGCTTCTTTCCTGGTGTATCTGGTCGAGAAGGACGATGAGACCACAGAGCTCCACAGAGACACTGATGGCCCTTCACCGACACCGGCCCCGCAGGACTTTGACACCTATGCAGACGCCCTCTGGTGGGGACTGGTGAGAATCACACACAGCACTCTTAGGCATTCAGAATATTTTTTAAAGGCTGCCTATTATGCAAAAATCACTTTTATAATGGATTTAAATGCAGTTGTGTGGCAACAGTGTGTGAATATAGCCAGCCTCTAATGGTAAAAAATGTATGAATTAGATTTTTTTATAATCACACTTCATATAGAAACACTTTGATTGGCATTCTCCCTTTGTACATGTCATCAGAGTGGGAAAGCCCCATTCATTAGTGATGATCTCTCTCTCATTAGCATAGACAGCCCTAGGTGAGAAGCAGCAATCTGCCATTTGATTTTTCACACCGTACCTGCTGAAAATAATGGCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44545
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000084303 Nonsense 288 401 6 11
ENSDART00000136141 None None 395 None 6
ENSDART00000145494 Nonsense 288 391 6 9
Genomic Location (Zv9):
Chromosome 2 (position 43128543)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 43178007
GRCz11 2 43027425
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCACCGACACCGGCCCCGCAGGACTTTGACACCTATGCAGACGCCCTCTG[G/A]TGGGGACTGGTGAGAATCACACACAGCACTCTTAGGCATTCAGAATATTT
Long Flanking Sequence:
CTGGAAACTGCTGGGATCTGCAATATACACACACAGCAAGGTATCCGAATGTGATGTGATGTACACAAACAGTCCGTAGCCCCCGATCAACATCGGAACGATTGTCCTGTTTGTTTGAATCATGTCATAGAAACTGATGGGGTCGGCAGTATACAAACAGTAAACAACGTAAACACACACTCACATCTTTTAAATCTGCTATAAACACACACACACATACACACACACACATACAGGGGAAAGTACATACGCAAGCACAAACAATCCTGTATCAGTGTCTGGTGATGTTTGATCTCCTGGCTGCAGACAAACTCAACTGTGTGCGTTTTTTAGGAGCTGATCACAGCGTGGTACATCGGCTTCCTGTCATTGATCCTGGCTTCTTTCCTGGTGTATCTGGTCGAGAAGGACGATGAGACCACAGAGCTCCACAGAGACACTGATGGCCCTTCACCGACACCGGCCCCGCAGGACTTTGACACCTATGCAGACGCCCTCTG[G/A]TGGGGACTGGTGAGAATCACACACAGCACTCTTAGGCATTCAGAATATTTTTTAAAGGCTGCCTATTATGCAAAAATCACTTTTATAATGGATTTAAATGCAGTTGTGTGGCAACAGTGTGTGAATATAGCCAGCCTCTAATGGTAAAAAATGTATGAATTAGATTTTTTTATAATCACACTTCATATAGAAACACTTTGATTGGCATTCTCCCTTTGTACATGTCATCAGAGTGGGAAAGCCCCATTCATTAGTGATGATCTCTCTCTCATTAGCATAGACAGCCCTAGGTGAGAAGCAGCAATCTGCCATTTGATTTTTCACACCGTACCTGCTGAAAATAATGGCAGCGACGAAGACCCTGTTTACACTGCCAGTTGAATGTGACCCAATTTAGATTTTTTGCTCATATGTGACAGATCGGATCTGTTCTATGTAAACACAAAATAAAAAAAAGCACACATAGGGATTTTCAGAAATCATTTTGAGGCCAGATATGT
Associated Phenotype:
Not determined