ZMP

raf1b

Ensembl ID:

ENSDARG00000059406

ZFIN ID:

ZDB-GENE-090826-2

Description:

LOC557109 protein [Source:UniProtKB/TrEMBL;Acc:Q4V900]

Human Orthologue:

RAF1

Human Description:

v-raf-1 murine leukemia viral oncogene homolog 1 [Source:HGNC Symbol;Acc:9829]

Mouse Orthologue:

Raf1

Mouse Description:

v-raf-leukemia viral oncogene 1 Gene [Source:MGI Symbol;Acc:MGI:97847]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa13517	Nonsense	Available for shipment	Available now
sa27701	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa13517

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
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Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000082519	Nonsense	71	685	3	18

Genomic Location (Zv9):

Chromosome 11 (position 506561)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	11	493298
GRCz11	11	519796

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

TGCTCATTTCTATTGAATATGTTGAAATTGTGTTGAAATAGGTGAACGTG[C/T]GAGCAGGAATGACGCTGCGCAACTGTCTCATCAAAGCCCTGAAAGTTCGA

Long Flanking Sequence:

AAAGGGTAGTGAACAACTTCAACTGTATATATCACGAAAATAAACTCGAAATATTAGATTTTTCCAATATCGTGCAGACTTACTATGAAGCATTTTCTATAAAACCCAAAAGTATTGTCTTGTTTTCCGAAATAATATGCTAAGTTTTTCCTTACATCAAGCAAAACAATCTTATTTCAAAGCAAAAACCAGATTTATTTACCCTTTGCTCACTCCACTGGCAGATTATTGTGCTTTGCAGTGCACTCATTCTGATCTTATTTTCACTTCAGTCAGAACTTCAGGGAAAATGTTTGATTACTGATACAAGTAATAATTAAATAAACATTAATAAAATACTAATGCAAGCAAATGATTGCAGATCCACCAAAAATATGGCTAAATAAAACACAATGCCCTCTGCAATGTTGCTTTCATATCCATGTGTTGATCTGTGTAGCTCAGGATGCATGCTCATTTCTATTGAATATGTTGAAATTGTGTTGAAATAGGTGAACGTG[C/T]GAGCAGGAATGACGCTGCGCAACTGTCTCATCAAAGCCCTGAAAGTTCGAGGTCTTCAGCCTGAATGCTGTGCTGTTTTCAAGCTTCAGCGGGAACATTCTGCGTAAGTTCTGAAATATGAAATAAAATAATACAATGAGAGCGACCCACATGTGTGATATCATTAACAGCAGTGTCTATCATGCATTTACTGTTTGGATGAAGCCATCAACATGAAGGACGTAAACATTTATTAACCCCCCTGTAATAAATAATAAAATAAATACAATTGAACATTATATTAATAACAGATGTTTATGGCTGATGGATGCTCATTTTCCAGTATAGTACTCAGTTTCACTAGCTCATATATCAAAAATAAATTAGCCTAAAGGGGCTAATAAAATTGTCCCTAAATGGTGTTTAAAAAATTAAAAACTGCTTTTATTCTAACCAAAATAAAACAATTAGACTTTCTCTAGAAGAGAAAATGTTATCAGACATACTGTGAATATATATAT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa27701

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000082519	Essential Splice Site	539	685	15	18

Genomic Location (Zv9):

Chromosome 11 (position 524249)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	11	510986
GRCz11	11	537484

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GCTGATGACCGGAGAACTGCCTTATTCTATGATTGGAAACAGAGATCAGG[T/C]GAGAGGCCAGAGACCAAATGTCACGTGAAAATGTTTGGACACCCTCAACT

Long Flanking Sequence:

TTCCTGCACGAGGGTCTGACGGTGAAGATTGGAGACTTCGGTTTGGCCACAGTAAAGGCTCGCTGGAGCGGCTCTCATAGAGTCGAGCAGCCGTCTGGATCCATTCTGTGGATGGTGCGTTAATAACTCGCATTTTAATATGATGTGCATTCAAATGACTTTATATAGACTCGGTCTGTAAAGTGAGCACCAAACATCTCAGTTTTTCCTTGGAAACACTTTTAAAATGTTTGAAAATCCTTTATTAATCTTAATAGACCTGTTCTGCCCCTTTAACAGATGTGAATGCGTCTGTGATGAGTGTGTCGTCAAGTTTCAGCTCTAACAGCGATGCTTCAGTGTGTTGTGTGCTTGATGTTCTCCTCAGGCTCCTGAAGTGATCCGCATGCAGGATAATAACCCGTACAGCTTCCAGTCAGACGTGTACTCGTACGGGATCGTCCTGTATGAGCTGATGACCGGAGAACTGCCTTATTCTATGATTGGAAACAGAGATCAGG[T/C]GAGAGGCCAGAGACCAAATGTCACGTGAAAATGTTTGGACACCCTCAACTTAAGTGTGTGAAAAATTCTTGTGACCTCATTATATTCTTAAAGGGGCAGTTCACCCAAAACTGAAAATTCTGTCATCATTTAATTACTGTGTACCTGTGTCTTTCTCTCTGTGTGTGTGTGTGTGTGTGTGTGCAGATCATCTTTATGGTGGGTCGGGGTTATCTGTCTCCAGACCTCAGTAAGCTGTATAAGAGCTGTCCTAAAGCCATGAAGAGACTGGTGTCCGACTGCATCCAGAAGACCAAAGAGGAGCGCCCACTCTTCCCACAGGTCAGCAACAGCACACATACACACATAACACAACACACACACATAATGCAGCACAGCACTGAGAAGTAGTTTCATAGTGTGTATTTAAAAATAATATACAACTCCAATGGTGTGTGTATATATATATATATATATACACCACTTTATTAGGTTATTAGGTACACCTTAATAGTACCGGG

Associated Phenotype:

Not determined