Busch Lab

ZMP

TGFBR2 (2 of 2)

Ensembl ID:
ENSDARG00000059363
Description:
transforming growth factor, beta receptor II (70/80kDa) [Source:HGNC Symbol;Acc:11773]
Human Orthologue:
TGFBR2
Human Description:
transforming growth factor, beta receptor II (70/80kDa) [Source:HGNC Symbol;Acc:11773]
Mouse Orthologue:
Tgfbr2
Mouse Description:
transforming growth factor, beta receptor II Gene [Source:MGI Symbol;Acc:MGI:98729]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa23405 Nonsense Available for shipment Available now
sa43192 Nonsense Mutation detected in F1 DNA Not yet available
sa43193 Nonsense Mutation detected in F1 DNA Not yet available
sa12495 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa23405
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000082466 Nonsense 32 659 2 10
Genomic Location (Zv9):
Chromosome 19 (position 953757)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 1280309
GRCz11 19 917905
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCTCTGGTGTTTCTGCAGCTCTTCTCCGCACTGCTGATCTCCGCATCTG[C/A]AGCTCCTGTAAGCCTCATCCAGTCAACTGTGTGTCAAATCAGTGCTTCTC
Long Flanking Sequence:
TTTTAACACTTATTTTTAACACTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATATGTATGTGTGTGTGTGTGTTTGTGTGTGTTTTTATGGGATGCTGACTGTTGTCTCATCTGATCGTGGTAATCTGGGGATCACATCAGTCTCTGCGGCTGCATGTGTTTGTGTTCATTTTCTGGCATGTCGAGCTGAATGTAGAGACACTGACATCATGCTTCATGTTGTAGAAATGTTTTTGCAAATTAAAACATCTGCTTGTGGTTAAAACCTCTGGCTTTGTGTTGATGTGTGAGTGAACATACAAACTGATGCTCTCTGGTAACGTAATAGTAATAACTAATAACAACAATAATAACATAATCATTATAACATAACTAATCGATCATCTGTGTGCGTGTGTGTGTGTGTTGTTGTTGATGAGTGAACGTATAAACTGATGTTCTCTGGTGTTTCTGCAGCTCTTCTCCGCACTGCTGATCTCCGCATCTG[C/A]AGCTCCTGTAAGCCTCATCCAGTCAACTGTGTGTCAAATCAGTGCTTCTCCAACTGCAGTGTGTCTACAGAGTGTGTGAATGAGCAGGACGTCTGTGCCGCCGTCTGGTATGAGCAACACTCCAGTCACACACACACATGTCTGAACTCGCTCATCCGCACATATACAGTACAATACCTAAGCTGTGTTCCAAATAACACACTATGCACTTATACACTATGTTTGTTTATGTTTGTTTTATACGCTCTGCACTTGTGCACTATGTATGTACACACAGACTATGCACTTATACACTATATAATACACTTTACATCATACAATATACACCATGCACTTCTGCACTACATAGCTATGCACTTATACACTATGCACTTATGCACTACATAGTTATGCACTTATACACTTATGCACTGCATAGTTATGCACTTATACACTATGCACTTATGCACTACATAGTTATGCACTTATACACTATGCACTACATAGTTATGCACTTATAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43192
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000082466 Nonsense 104 659 3 10
Genomic Location (Zv9):
Chromosome 19 (position 955717)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 1282269
GRCz11 19 919865
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGATGCTCGGTGTGATGGTGGAGGATATTCTCATCTCGGAGTGTGTGTTG[C/T]AGGAACAAAACATTCACGGAAGACACCTGCGTGTGTGTAGCTGCACAGGA
Long Flanking Sequence:
TATACCAGAACACAGATGGATTTCAAACACATGCGAGCACTGTTGCATTATGGGTGTTGTAGTTTTGTTTGTGACTGTTATTACAGGAAAAGAGAAACGGCAGCATGTGCTTGTTTCACTTTCTTTGTGATTCAGGAAGAACAGCTCAAAATAAACTAACGCTGACTATGTTATTAAAGCAGCGTGCTTAATCTGCATATTCATTCATTCATTCATTTTCTTTTCAGCTTAGTCCCTTTATTAATTTGGGGTTGCCACAGCGGAATGAACCGCCAACTTATTCAGCACATGTTTAAAATGCATCTTGGGATACTGCAGGACACAAGCGGAGTGTGTTCAGCTGCTGACTTTGCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTGAAGGTGGAGAGATGCTGGACTGGTGATGGTGGAGACTCTCTGTCATGACCCACTAAAGCCGATGCTCGGTGTGATGGTGGAGGATATTCTCATCTCGGAGTGTGTGTTG[C/T]AGGAACAAAACATTCACGGAAGACACCTGCGTGTGTGTAGCTGCACAGGAGACCAGTGCAACCAGAACTTGCTGCTGCGCAAACTCACTGAGGAGGAGAAATGTGAGTATAGAGAGGTGTGTGTGTGAGAGAGAGTGTGTGTGTGTGTGTGTGTGTGTTGCTAATTTGTTTTTGTGTTTATGTGTTCAGCGATTACTCTTATATGCTCAGAATGTCAGTTTTCCTACATATTGCAGATATTGCTAGAATGACAGCATGAATGTGTGTGTGTGTGTGTGTACAGTGTCGAAGACAAACTCCAGCAGCGGCTTCAGACTCAAACAGAACTGTAAGTTTTGTGATGTTGAGTCTTCGGTGTGTAACGCCAGCGGTGTGTGTGAGTCCGCCTGCGGCATAAACTCCATCTGTGAGACACCGGACGAGGTCTGCGCCAGCGCCTGGTACGCAACACACACTGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43193
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000082466 Nonsense 106 659 3 10
Genomic Location (Zv9):
Chromosome 19 (position 955723)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 1282275
GRCz11 19 919871
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCGGTGTGATGGTGGAGGATATTCTCATCTCGGAGTGTGTGTTGCAGGAA[C/T]AAAACATTCACGGAAGACACCTGCGTGTGTGTAGCTGCACAGGAGACCAG
Long Flanking Sequence:
AGAACACAGATGGATTTCAAACACATGCGAGCACTGTTGCATTATGGGTGTTGTAGTTTTGTTTGTGACTGTTATTACAGGAAAAGAGAAACGGCAGCATGTGCTTGTTTCACTTTCTTTGTGATTCAGGAAGAACAGCTCAAAATAAACTAACGCTGACTATGTTATTAAAGCAGCGTGCTTAATCTGCATATTCATTCATTCATTCATTTTCTTTTCAGCTTAGTCCCTTTATTAATTTGGGGTTGCCACAGCGGAATGAACCGCCAACTTATTCAGCACATGTTTAAAATGCATCTTGGGATACTGCAGGACACAAGCGGAGTGTGTTCAGCTGCTGACTTTGCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTGAAGGTGGAGAGATGCTGGACTGGTGATGGTGGAGACTCTCTGTCATGACCCACTAAAGCCGATGCTCGGTGTGATGGTGGAGGATATTCTCATCTCGGAGTGTGTGTTGCAGGAA[C/T]AAAACATTCACGGAAGACACCTGCGTGTGTGTAGCTGCACAGGAGACCAGTGCAACCAGAACTTGCTGCTGCGCAAACTCACTGAGGAGGAGAAATGTGAGTATAGAGAGGTGTGTGTGTGAGAGAGAGTGTGTGTGTGTGTGTGTGTGTGTTGCTAATTTGTTTTTGTGTTTATGTGTTCAGCGATTACTCTTATATGCTCAGAATGTCAGTTTTCCTACATATTGCAGATATTGCTAGAATGACAGCATGAATGTGTGTGTGTGTGTGTGTACAGTGTCGAAGACAAACTCCAGCAGCGGCTTCAGACTCAAACAGAACTGTAAGTTTTGTGATGTTGAGTCTTCGGTGTGTAACGCCAGCGGTGTGTGTGAGTCCGCCTGCGGCATAAACTCCATCTGTGAGACACCGGACGAGGTCTGCGCCAGCGCCTGGTACGCAACACACACTGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12495
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000082466 Nonsense 352 659 6 10
Genomic Location (Zv9):
Chromosome 19 (position 961047)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 1287599
GRCz11 19 925253
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACAACACTGAGCTGCTGCCCATCCAGCTGGACAGAGTTGTGGGAAAAGGA[C/T]GAWTCGCAGACGTTTATAAAGCCAAGCTGAAGCAGAGCGCAGACTCCTTC
Long Flanking Sequence:
TAATCATATATTTAATTTTTTTTAAATCCATATTTTTATATTATTTCTTTTATATTTTGTAGCATTTGGTTTAAATGCATTTTTTTGTTTAATTTACATTGAATAAAGATACTAAAACAATTAAATATGATCATTTATTAATTTATTTTTTATTAATCTTATATTAATTGTTTTTTTTATTGTTTTTCTCATGCTCAGATTTGAAACAATATCCAGGGGTTCAGTTCAATCCCCCCTCTGAGTCATCATGGTTCAGTCTGGCTCCAGTGCTGATCTCCGTCTTTGTCCTCATCCCAATCGTCCTGCTCTCCGTCTTCTACTGTTACCACATCAGTCAGCACAAACTGAAGCTCCCCAATAAGAAGAGTCTGGACAGCGAGAGATGCAACATTTTCATGAATCCAGAAGAGCATTCGGACAGCAGCTCCATCAACGCCAACAGCCTGAACCACAACACTGAGCTGCTGCCCATCCAGCTGGACAGAGTTGTGGGAAAAGGA[C/T]GATTCGCAGACGTTTATAAAGCCAAGCTGAAGCAGAGCGCAGACTCCTTCCAGACGGTGGCGGTAAAGATCTTCCCGTATGAGGAGTTTTCCTCGTGGAAGAGTGAATGGCAGATTTTCTCTGACGTCGAACTTCGGCATGAAAACGTCCTGCAGTTTCTGACAGCAGAAGAGCGGACGGCAGAGCGACAGTATTGGCTGATCACGGCCTATCACGAGCGAGGAAACCTGCAGGTGGGGACGACTGCCAAACTTTTATGACTCTTTGGTCTCAAATCAGTGATTTTAAGTGGATAAAAAATTGGGAAGTTCAGGTGATTTCAGTCATTACCGTTTCAAACTTTTTTAAAAACTAAAAAAAATTTCCACTAGGGGGCGATTTGTGTAAAGGCCGATTTGCAGACGAATGCAGTAGTGATGGCTGCTTACGAAGCATTGCTTCATGAAGCTTAAAAACTTTTATGAATCTTTGGTTTCGAATCAGTGATTTTAAGCATGTAT
Associated Phenotype:
Not determined