ZMP

si:ch211-241b2.5

Ensembl ID:

ENSDARG00000059310

ZFIN ID:

ZDB-GENE-081104-192

Description:

Novel protein [Source:UniProtKB/TrEMBL;Acc:B8A5Z7]

Human Orthologues:

CD274, PDCD1LG2

Human Descriptions:

CD274 molecule [Source:HGNC Symbol;Acc:17635]
programmed cell death 1 ligand 2 [Source:HGNC Symbol;Acc:18731]

Mouse Orthologues:

Cd274, Pdcd1lg2

Mouse Descriptions:

CD274 antigen Gene [Source:MGI Symbol;Acc:MGI:1926446]
programmed cell death 1 ligand 2 Gene [Source:MGI Symbol;Acc:MGI:1930125]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa43560	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa37203	Nonsense	Mutation detected in F1 DNA	Not yet available
sa32323	Nonsense	Available for shipment	Available now

Mutation Details

Allele Name:

sa43560

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > G

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000082395	Essential Splice Site	274	502	6	9
ENSDART00000139098	Essential Splice Site	268	465	5	8

Genomic Location (Zv9):

Chromosome 21 (position 2498349)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	21	2374386
GRCz11	21	2400210

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CAATAATCTATCATATAAACGTGTGTGTGACCTCTGCTTTATCTGTTGAC[A/G]GGTCAGAAAAACAGAAGAAACGAAGCCTCTAAATGTGCTTACCTCTTCCC

Long Flanking Sequence:

ACAATGTAGAGTAGATCTGTTTTCAAAGCATTCCTCTATACACTATTTATAAAGTGTTTGATTCTTTCCTAAAATAGGTCGTGATTGATTAGTTTTGTGAGTCAGCAGCATGTGATTTAAAGATATTGTAAGTGTATTATCATCAGTGTATGAGGAAAAGAATAACAAGGTTATATCACAGGTAAATCCCACATTAGTCACTCACGTGAGGAGGAAACTTGAAATCAAATTAAAAGCATTCAGTTTTATTGTTTTGACGTTGTGACAGTATATATAATTAATGATATTGCAATGTGGGCCCGTTTTTCAGCAATAATCATGACGGTTGCATTTTTTTTATGTTGTTTATTTTGTGTGTGTTTCTGTCAACAGCTGATTGTTATAAAATCATTACTATGCAAAAAAATGCTGTTTCATTTCCTCTTTTAATGCGCAGTCATGAGTGAGTTCCAATAATCTATCATATAAACGTGTGTGTGACCTCTGCTTTATCTGTTGAC[A/G]GGTCAGAAAAACAGAAGAAACGAAGCCTCTAAATGTGCTTACCTCTTCCCACAATCATCCTCTGTCAACACTGACTGTGAGTTTTTATGTCATTTACAGCAAGTCATTGAGCTTGTTATGATCGATGTGAAGTTACTGTAAAAGAGCTGTAAAATCAACATGCATGCAACACTGGCAAAAATACCTCAATTCCAGTATGGGAAGTTATATTATAATCATATTTTTATGATTATAAAATACTACAGTTTTATTCAATTATATATTGTTTATAAATATATGCATCACTTTATGTATTATCTTTAAGCAAGGAAATATAGTATCAATAATATATAATAGATAATTTTTTCATCATAATAGCTTGACTTAATTAATAAAACAATTACTACATTAATATATTATTGATAATTTTTGTTGTCTAATTACAATCTACAACCAAAACATGATAAAACAAAATAAAACAATTACTTAATTAATATATTATTGATGACAATTTAATTAAT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa37203

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000082395	Nonsense	452	502	9	9
ENSDART00000139098	Nonsense	446	465	8	8

Genomic Location (Zv9):

Chromosome 21 (position 2503277)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	21	2369458
GRCz11	21	2395282

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AAGCAGTCTCTTAAAGGGCCGGAGGACTGTTTGCTGATCCTCGATGATTA[T/A]CAAGAGGGAAATAAAGACTTGGAGGAGTTTTTAAAGGACCATCAGACGTG

Long Flanking Sequence:

CTCAAACAGACCTATTCTGAGAGTTTAACTAAGAACAAATAGTGCAGATGTCGTCGTTCGATTACAACATTTTGTTCTTCTTAACATGCACAAATGAAATGTTCAGCACAAAGCTAGCAATGTGCGCCAACAAAATCAATATGGTTAGTTTTGATTTCACGTTTGCTTTAAACCACATCATCATTTCTCCATTCCAGAGATGGCCACTGCGTAAACATCAGCTCCGTCATTCCTGAAAAGGGGCAGATTCTCCTCCTCCTCGGAGACTCCGGCTGCGGGAAAACCACGTTCACCCAAATCCTGTCCTACAGCTGGGCATCCCGTTCCCAGACAGACCCGTTTAACACCCGCCGGCTCCGTCTGCTCCTGCTGCTCCACTGCAGCCAAAATAAAGGGAATTTAAATCAGATTATCAACTCCAGCGTTCAACATGAACGACCAGTGGATGTAAAGCAGTCTCTTAAAGGGCCGGAGGACTGTTTGCTGATCCTCGATGATTA[T/A]CAAGAGGGAAATAAAGACTTGGAGGAGTTTTTAAAGGACCATCAGACGTGTCGAGTGTTAATAACATCACGTCCTGGAGTTTGTCCAAACCTGGAGAAAACCGTCAGGACTGTATTGCATCTCATTCATAAACCTGAAGAGTCTTCAACATGATGATGCATGCATTCGTATTTGCAAAGACTGTGAGGAGGCATTCAGCGACTCGACGAGAAGGAGCAATGCACACACAAAGTGCTAATTATACAAAGGAGCTGTGTTTATATATATATATAGAGAGAGAGTGAGAACAATGTTTCTACAGGTGGTTTGTCAAGCCCACTCACCTGTGTGAGGCGCACTTCATTAATGCACAATGGTATGGCATGGTGCCTCAGTGGTTAGCACTTTCACCTTATAGCTAGTAGGTTGATGCTTCGAGTCTCATCTGGGCCAGTTGGCATTTCTGTGTGGAGTTTGCATGTTCTCCCCGTGTTTGCGTGGGTTTCCACCAGGGGCTTTGG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa32323

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

G > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000082395	Nonsense	454	502	9	9
ENSDART00000139098	Nonsense	448	465	8	8

Genomic Location (Zv9):

Chromosome 21 (position 2503281)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	21	2369454
GRCz11	21	2395278

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AGTCTCTTAAAGGGCCGGAGGACTGTTTGCTGATCCTCGATGATTATCAA[G/T]AGGGAAATAAAGACTTGGAGGAGTTTTTAAAGGACCATCAGACGTGTCGA

Long Flanking Sequence:

AACAGACCTATTCTGAGAGTTTAACTAAGAACAAATAGTGCAGATGTCGTCGTTCGATTACAACATTTTGTTCTTCTTAACATGCACAAATGAAATGTTCAGCACAAAGCTAGCAATGTGCGCCAACAAAATCAATATGGTTAGTTTTGATTTCACGTTTGCTTTAAACCACATCATCATTTCTCCATTCCAGAGATGGCCACTGCGTAAACATCAGCTCCGTCATTCCTGAAAAGGGGCAGATTCTCCTCCTCCTCGGAGACTCCGGCTGCGGGAAAACCACGTTCACCCAAATCCTGTCCTACAGCTGGGCATCCCGTTCCCAGACAGACCCGTTTAACACCCGCCGGCTCCGTCTGCTCCTGCTGCTCCACTGCAGCCAAAATAAAGGGAATTTAAATCAGATTATCAACTCCAGCGTTCAACATGAACGACCAGTGGATGTAAAGCAGTCTCTTAAAGGGCCGGAGGACTGTTTGCTGATCCTCGATGATTATCAA[G/T]AGGGAAATAAAGACTTGGAGGAGTTTTTAAAGGACCATCAGACGTGTCGAGTGTTAATAACATCACGTCCTGGAGTTTGTCCAAACCTGGAGAAAACCGTCAGGACTGTATTGCATCTCATTCATAAACCTGAAGAGTCTTCAACATGATGATGCATGCATTCGTATTTGCAAAGACTGTGAGGAGGCATTCAGCGACTCGACGAGAAGGAGCAATGCACACACAAAGTGCTAATTATACAAAGGAGCTGTGTTTATATATATATATAGAGAGAGAGTGAGAACAATGTTTCTACAGGTGGTTTGTCAAGCCCACTCACCTGTGTGAGGCGCACTTCATTAATGCACAATGGTATGGCATGGTGCCTCAGTGGTTAGCACTTTCACCTTATAGCTAGTAGGTTGATGCTTCGAGTCTCATCTGGGCCAGTTGGCATTTCTGTGTGGAGTTTGCATGTTCTCCCCGTGTTTGCGTGGGTTTCCACCAGGGGCTTTGGTTAC

Associated Phenotype:

Not determined