Busch Lab

ZMP

lck

Ensembl ID:
ENSDARG00000059282
ZFIN IDs:
ZDB-GENE-040617-1, ZDB-GENE-040617-1, ZDB-GENE-040617-1
Description:
lymphocyte-specific protein tyrosine kinase isoform 2 [Source:RefSeq peptide;Acc:NP_001035418]
Human Orthologue:
LCK
Human Description:
lymphocyte-specific protein tyrosine kinase [Source:HGNC Symbol;Acc:6524]
Mouse Orthologue:
Lck
Mouse Description:
lymphocyte protein tyrosine kinase Gene [Source:MGI Symbol;Acc:MGI:96756]

Alleles

There are 2 alleles of this gene:

Allele Name Consequence Status Availability
sa36417 Nonsense Mutation detected in F1 DNA Not yet available
sa410 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa36417
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000082356 Nonsense 23 503 1 12
ENSDART00000105478 None None 503 None 13
ENSDART00000126663 Nonsense 23 503 2 13
Genomic Location (Zv9):
Chromosome 17 (position 25168152)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 25359843
GRCz11 17 25378234
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTTTGATCCTGATGATGAATTCTCCTACCATCCAGATGAATGGTGTGAC[C/T]AGTGTAACTGCCCCAAGCCTCCAGTCAGTCAGGTGTGTGTTTGAGCATCT
Long Flanking Sequence:
TACACGATTCCTAAATATGTTGTTTTTTTTGTGAGAGAGACACCATCCTATAATAAATAGGTCTAAAATAATAATTGGAAAGGTTTTATGCATTTGTATTGTGTTTTATCATTCATTTTAAGCCAATTATAAGATTATAAGTCTTAATCTTAAGGATTATCTTAATGTTTATCTATCATATTGCATAATTTATTTATATTTATATAATTTATTTATTATTAATCAGCTTTTCAGTTGAATATATATTTTTACATGACTCTTTTTGGAAAAGCCTTGTGAAAAGTACTCAATAATATCAAAACATATTTATTTCTCATTAATTTAGGATTGTTTGGAAAGTGCTAGATCAGTTCCTCTTGAATTTATACACCGATTAATGTCTAACGCAGTCAGCATTCTTATAGTTGCACCATTTTCTCTCATGCTTAGTAAACATGGGGAACTGCGGCTCTTTTGATCCTGATGATGAATTCTCCTACCATCCAGATGAATGGTGTGAC[C/T]AGTGTAACTGCCCCAAGCCTCCAGTCAGTCAGGTGTGTGTTTGAGCATCTGTGTTTGTGTGTGTACTGTGTTTAAATAATGGCTTCCACTTCCGGTTTAGAAAACTTCCACTCAACATGACTGAAAAATCATTCTAATTATAAAGCTCAACTAAATAATAAGACACTGTTTGAAAGAGCTATATATTTTCTATCATGCTGTTTTTTTTAAGTGAGAAAATAAGTATGTTTTTTACAAACCGCGCTAAAACATATAATTGTCTCCTTATTTTTCTTAGCATTTTAAAACATCAATTTTGATCATATACAGTACATTTATAAACAACAACCATATGTGTATATAAACCTATACAGAATTCACTTTCAGTGCAACCATAATACTGCTAATCTGCTGATACTCTTACACTTTTAATACTCTTGCTAATACTCTTAGACGTTAAAGATTTCTTTAGATGGTGTAAGGGGAATAATGTCACCTTATTCTATCCTGGTTTAGCAAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa410
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000082356 Nonsense 120 503 5 12
ENSDART00000105478 Nonsense 120 503 6 13
ENSDART00000126663 Nonsense 120 503 6 13
Genomic Location (Zv9):
Chromosome 17 (position 25162106)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 25353797
GRCz11 17 25372188
KASP Assay ID:
554-0269.1 (used for ordering genotyping assays)
KASP Sequence:
CTCAAATGAAGTGAAAACTCTAATAAAATGACATCGTTGTGTTGCAGGTG[G/A]TTCTATAAAAATCTCTCCAGGAATGACGCCATGAGGCAGTTACTGGCTCC
Long Flanking Sequence:
TGATCCTGAATGGTACATGGCGGAGTCTCTGTTCACCGGCCAGAGGGGTTACATACCAAAGAACTTTGTAGCAAAACTGAACAGCATGGAGACAGAACCGTAAGTAATGCAATGCTCACTCGCATACAGTCACATACACCCAAACAAATACACACAATTAAATGTATTTATGCAGATGAAATCATCAGAATGACGTCTGGGAAATACCACCCACTTCAGTGGCTAAAATGTTTCACTTAGGATACCCCTTACCCACTTATGAAGACAGATGATCAAGAAGTCAGTAAAGAAAAAAAAATACTCCCACAAAACACACACGTTTCTGAGCATCGCTATGTTTAACCACTGCAGTAGCTGCTGACACCACATTTCTGCGTTAAGTTCCAGTCTGTGAATGTTTCTCTTCCAATCGTGGGAGGAGTGAAAAGCACCAAGTCTGAATTTCTGTAACTCAAATGAAGTGAAAACTCTAATAAAATGACATCGTTGTGTTGCAGGTG[G/A]TTCTATAAAAATCTCTCCAGGAATGACGCCATGAGGCAGTTACTGGCTCCTGGCAACACACAGGGCTCGTTTCTCATCAGAGAGAGCGAGACGCAGCCAGGTAGCCTTGCACTTTTCCCCACAACAACAACAAACTAAAAATGTACAGTATTATAAGGGCACATCTGACAGTGCTATCACATTATGGCTTTGATATCTTTCTAGATTTAAATATGAAAGTTAAACTAAATGTAAAAAATTTATGTAATTTTTATAAATAAACAACAGTAAGACATATTATTAATGATATAAATAATGCATTTCTGCTTTTTCAATTCTATACCCAGCTCATCTCAGCTATAATTAATGCATTAGCATTGTTATGTAATTTTGCATATTAGTTATTATTAATATCTTAATAAATATATTAGGTCACACTTTATTTTGATGGTTCGTTGAATTTAAGCTACATTGCATCTACATGCCAGCTATATCTCATTAGATTATAAGTAGACTGTTAG
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037
whole organism
ZFA:0001094
quality
PATO:0000001
normal
PATO:0000461