ZMP
ROCK1
Ensembl ID:
Description:
Rho-associated, coiled-coil containing protein kinase 1 [Source:HGNC Symbol;Acc:10251]
Human Orthologue:
ROCK1
Human Description:
Rho-associated, coiled-coil containing protein kinase 1 [Source:HGNC Symbol;Acc:10251]
Mouse Orthologue:
Rock1
Mouse Description:
Rho-associated coiled-coil containing protein kinase 1 Gene [Source:MGI Symbol;Acc:MGI:107927]
Alleles
There are 3 alleles of this gene:
Allele Name | Consequence | Status | Availability |
---|---|---|---|
sa2058 | Nonsense | F2 line generated | Not yet available |
sa5712 | Nonsense | F2 line generated | Not yet available |
sa39747 | Splice Site, Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa2058
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000081976 | Nonsense | 597 | 1359 | 16 | 33 |
ENSDART00000081976 | Nonsense | 597 | 1359 | 16 | 33 |
Genomic Location (Zv9):
Chromosome 2 (position 3020598)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 2 | 3027623 |
GRCz11 | 2 | 2869522 |
KASP Assay ID:
554-3139.1 (used for ordering genotyping assays)
KASP Sequence:
GCAKAAACCGGGAGCTGCAGGAGAAGATTCGCGCCGCAGAAAGTGTCAAA[C/T]AACAGCTGGAGAAAGAGCTGCTGCAGCTGCAGACCACGCTGGACACCGAG
Long Flanking Sequence:
CCCTAAACGACTGATAGCCCCGCTTTAAACAACTGATAGCCCCACCCTAAATAACTGATAGCCCCACCCTAAAGGACGGTTAGCCCTGCCCTAAACGACTGATAGCCCCGCCCTAAACGACTGATAGCCCCACCCAAAATGACTGATAGCCCCACCCTAAACGACTGATAGCCCCGCCCTAAACAACTGATAGCCCCACCCAAATTGACTTATAGCTCCGCCCTAAAAGACTGATAACCTCACTGGAACTGTAAATCCTCATTTTTGGCTCTTCTATCTTTATATTGAGGCCTGTTTTTGTACCACGTGACATTCAAACAACATCTCACACACAACATTGTCATCCACAGCTGGGGGAAGCCAACGATCTTCTGCGCGCTGAGTCAGACACAGTGATGCGCCTGAGGAAGAGCCACACAGAAATGGGCAAGACTATGAGCCAGCTGGAGAGCATAAACCGGGAGCTGCAGGAGAAGATTCGCGCCGCAGAAAGTGTCAAA[C/T]AACAGCTGGAGAAAGAGCTGCTGCAGCTGCAGACCACGCTGGACACCGAGAGACGGAGCTGCAGCCAAGGCTCAGAGGAGATCCGAGAACTGCAAGGTGAGACACCTCAGTTCAGTTTATCTTTATTTCACTGGCGCTTTTACAATGTAGATTGTGTCAAAGCAGCTTAAGACAGAAGTTCTAGTAAATGTAAACAGAGTCAGTTCAGTTTTCAGAGTTGAAGTTCAGTTTAATTCAGGTCAGTGTGGTTTAAATTTCACTGCTGAAAGTCCAAACACTGAAGAGCAAATCCAGTGATGCACAGCTCCAAAAGTGCCAAACCAAGCAAGCCAGTGGAGACAGTGGCGAAGAAAAAACTTCACCAATTGACCAAAGTGAAGGAAAAACGGATACCAATAGTTTTAGACTTGTTTGGTTTGTTTACTATAATAAACTTTGGTGTAGACCAGGGGGGTCAAACGTACGGCCGGATCAGACCCGCAAACAAATTAATTGCGGCC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa5712
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000081976 | Nonsense | 597 | 1359 | 16 | 33 |
ENSDART00000081976 | Nonsense | 597 | 1359 | 16 | 33 |
Genomic Location (Zv9):
Chromosome 2 (position 3020598)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 2 | 3027623 |
GRCz11 | 2 | 2869522 |
KASP Assay ID:
554-3139.1 (used for ordering genotyping assays)
KASP Sequence:
GCAKAAACCGGGAGCTGCAGGAGAAGATTCGCGCCGCAGAAAGTGTCAAA[C/T]AACAGCTGGAGAAAGAGCTGCTGCAGCTGCAGACCACGCTGGACACCGAG
Long Flanking Sequence:
CCCTAAACGACTGATAGCCCCGCTTTAAACAACTGATAGCCCCACCCTAAATAACTGATAGCCCCACCCTAAAGGACGGTTAGCCCTGCCCTAAACGACTGATAGCCCCGCCCTAAACGACTGATAGCCCCACCCAAAATGACTGATAGCCCCACCCTAAACGACTGATAGCCCCGCCCTAAACAACTGATAGCCCCACCCAAATTGACTTATAGCTCCGCCCTAAAAGACTGATAACCTCACTGGAACTGTAAATCCTCATTTTTGGCTCTTCTATCTTTATATTGAGGCCTGTTTTTGTACCACGTGACATTCAAACAACATCTCACACACAACATTGTCATCCACAGCTGGGGGAAGCCAACGATCTTCTGCGCGCTGAGTCAGACACAGTGATGCGCCTGAGGAAGAGCCACACAGAAATGGGCAAGACTATGAGCCAGCTGGAGAGCATAAACCGGGAGCTGCAGGAGAAGATTCGCGCCGCAGAAAGTGTCAAA[C/T]AACAGCTGGAGAAAGAGCTGCTGCAGCTGCAGACCACGCTGGACACCGAGAGACGGAGCTGCAGCCAAGGCTCAGAGGAGATCCGAGAACTGCAAGGTGAGACACCTCAGTTCAGTTTATCTTTATTTCACTGGCGCTTTTACAATGTAGATTGTGTCAAAGCAGCTTAAGACAGAAGTTCTAGTAAATGTAAACAGAGTCAGTTCAGTTTTCAGAGTTGAAGTTCAGTTTAATTCAGGTCAGTGTGGTTTAAATTTCACTGCTGAAAGTCCAAACACTGAAGAGCAAATCCAGTGATGCACAGCTCCAAAAGTGCCAAACCAAGCAAGCCAGTGGAGACAGTGGCGAAGAAAAAACTTCACCAATTGACCAAAGTGAAGGAAAAACGGATACCAATAGTTTTAGACTTGTTTGGTTTGTTTACTATAATAAACTTTGGTGTAGACCAGGGGGGTCAAACGTACGGCCGGATCAGACCCGCAAACAAATTAATTGCGGCC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa39747
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Splice Site, Nonsense
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000081976 | Splice Site, Nonsense | 1202 | 1359 | 30 | 33 |
Genomic Location (Zv9):
Chromosome 2 (position 3042986)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 2 | 3050011 |
GRCz11 | 2 | 2891910 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACAAGGTGACGTTTACCGAGCAGAGACTGATGAAATCCCAAGAATATTC[C/T]AGGTCAGTTTTTGAATATATTTTCTAATAATAAAGGTCATAAAATGCCCC
Long Flanking Sequence:
TTGTCTGCTGTTTAAAAACCAGCCTAGAGCGCCGTCTGCTGTTAAACACTAGCCTAGAGCGCCGTCTGTTGATAAAAACAAGCCTAGAGCGCCGTCTGCTGTTAAACACTAGCCTAGAGTGCCATCTGCTGTTAAGCATTACACTGGAGGGCCGTCTGCTGTTAAACACTAGCCTAGAGCGCTATCTGCTGTTGAACACTAGCCTAGAGCACTGTCTGCTCTTAAACATTAGCCTAGAGCACTGTCTGCTTTTAAAACTATCCTAGAATGCCATCTGCTCTTAAACACTAATCTAGAGCACCGTCTGCTGTTAATCACCAATCCAATCCATGTTATCAGTTATTTCATTCATTCCTGTTTGTAAAATGCAATGATTTACTTGCTACTATATTAAAATGTATGTGTTTTTGTGTTCACATCACAGTAAACTTTTCCATGTGCGTCCTGTCACACAAGGTGACGTTTACCGAGCAGAGACTGATGAAATCCCAAGAATATTC[C/T]AGGTCAGTTTTTGAATATATTTTCTAATAATAAAGGTCATAAAATGCCCCATAATGATATAATCACCATATGCGTGCTATTTAAAGAGTGTGTTAGTGATTTGGTGGTCCACAATCCGTGTACACGTTGCTTATTACACACACAGGGAGGCACAGCAGCACACAACCTTAAGTCTGCCATGTAAATAACAAATCTGCTTGGCAAGATCCCAACTCACTCGTAAAGGGAATGGGAGATCAAACTCTGATGGGTTTAATGCACATTACTCTCAAAAACACACCCATTACTGATTAAGAGAATAAAGACAACCCCTTTAGGTTATGCGCTGGGTAGGCAGACTGTTTTTCACACCGTTAAAACAGCAAAAGTGGATTCAGATATACCCTAACTGTGCATCTCTAAAATAGATCATTAAAATGAGCTTCACAACCTTTGATATCTTCACCTGAATCTGCAAATTGAATGAGAGTGTTTGTGGTTTAGATCCTGTATGCTAATGA
Associated Phenotype:
Not determined