Busch Lab

ZMP

apc

Ensembl ID:
ENSDARG00000058868
ZFIN ID:
ZDB-GENE-031112-7
Description:
adenomatosis polyposis coli [Source:RefSeq peptide;Acc:NP_001137312]
Human Orthologue:
APC
Human Description:
adenomatous polyposis coli [Source:HGNC Symbol;Acc:583]
Mouse Orthologue:
Apc
Mouse Description:
adenomatosis polyposis coli Gene [Source:MGI Symbol;Acc:MGI:88039]

Alleles

There are 8 alleles of this gene:

Allele Name Consequence Status Availability
sa34805 Nonsense Available for shipment Available now
sa12033 Splice Site, Nonsense Available for shipment Available now
sa6136 Nonsense Mutation detected in F1 DNA Not yet available
sa61 Nonsense Available for shipment Available now
sa21628 Nonsense Available for shipment Available now
sa27530 Nonsense Mutation detected in F1 DNA Not yet available
sa9511 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa34805
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000044432 Nonsense 388 2755 10 16
Genomic Location (Zv9):
Chromosome 10 (position 1909092)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 1852955
GRCz11 10 1880669
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGAGGCTCGCGCCCGAGCCAGCGCCGCCCTGCACAACATCATTCACTCA[C/T]AGCCGGACGACAAGCGCGGACGCAGAGAGATCCGCGTACTGCACCTGCTG
Long Flanking Sequence:
AATAAGACTTTCTCCAGTAGAACAAATATCATAGAAAATACTGTGGAAATTTCCTGAGTCTGCTCAACATCATGTGTGAAATATATGACGAAGAAACTAAAATATGCAGGAGGGCAGATAATTCTGACTCCAACTGTTCATATTTATTTATCAAAGGCACATGACATTTGGTTAAAAAATATATTATTATATAACTAAGTCTGCCTTATGAAGGGGGTTTGTTTGAGTTTTAATGGAGTGTTTTGTGGTTTCAGGTGGAAATGGTGTACTCTCTGCTGTCCATGCTGGGCACTCATGATAAAGACGACATGTCCCGAACACTGCTGGCCATGTCCAGCTCTCAGGACAGCTGTATCGCCATGCGTCAGTCGGGCTGCCTGCCCCTGCTCATCCAGCTCCTGCACGGAAACGACAAGGACTCTGTGCTGCTGGGAAACTCACGTGGCAGTAAAGAGGCTCGCGCCCGAGCCAGCGCCGCCCTGCACAACATCATTCACTCA[C/T]AGCCGGACGACAAGCGCGGACGCAGAGAGATCCGCGTACTGCACCTGCTGGAGCAGATCCGGGCCTACTGCGAGACCTGCTGGGAGTGGCAGGAGAGCCACGAGCGAGGTGTGGACCAGGACAAAAACCCCAGTGAGTGACCCTTTAAATTGCGCTGTACAAGCAGAGAATTGCATGCTGTCCTTATCGTTATGTCCTTATGCGTGTCATTATTTTTCAGTTTCAGGAATAAAGCCGCTATATATATATTTATGTACATATATATATATATATATATATATATATATATATATATATATATATATATATATATAAATATGTATGTATGTATGTATGTATATATGTATAAATATGTATGTATGTATGTATGTATATATGTATGTATGTATATATATATATATATATATATATATATATATATGTATGTGTGTGTGTGTGTGTGTGTGTATATATATATATATATATATATATATGTATGTGTGTGTGTGTGTGTGTGTATG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12033
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Splice Site, Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000044432 Splice Site, Nonsense 536 2755 13 16
Genomic Location (Zv9):
Chromosome 10 (position 1911937)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 1855800
GRCz11 10 1883514
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCATGAGGGCCATGGTGGCTCAACTGAAGTCAGAAAGCGAGGACCTACAG[C/T]AGGTATTACTCTTTAGATATGCATTTCATATTCTTDAATTTTGTATTANTG
Long Flanking Sequence:
GTGTGGTATTTTGAGCTGAAACTTCACACACACACACTCTAGGAACATCAGAGACTTATTTTATATCCTGTAAAAAGGAGCATAGTAGGTCCCCTTTAAAAACAGAAAGTGTTTGGCCCTTTCTAACATGTATTTATTATATTATGTGTTATTTTGAAACAATATTAGCTGATTATGTCAATGCACGGTTCATGCAGGCGGTCTTCAGGCGATCGGGGAGCTGCTGCAGGTGGACTGCGAGATTTACGGTCTTACCAATGATCACTACAGTGTTACACTAAGACGATATGCTGGGATGGCTCTGACTAATCTGACCTTTGGAGATGTTGCTAACAAGGTGCGTTATTTCTCTCGTTGTTTTCTGTATAGATTTAATTTTACTGTTTATTAATGTATTAATTTGCCACTTTTTATGTCGTCCACAGGCAACACTTTGCTCAATGAAGGGTTGCATGAGGGCCATGGTGGCTCAACTGAAGTCAGAAAGCGAGGACCTACAG[C/T]AGGTATTACTCTTTAGATATGCATTTCATATTCTTGAATTTTGTATTATGGGTAACACTTTGCATTTAGGTTGCATTAGTTAATGCATTAGTTAACACGATATGAGAGGCGTCTTTAAGCTGCAGTACCAAAAAAGCCTTTTATAAAAAGTACTCAATACATTTTAGTAGTTCAGGACTTTCTTTTTCTGTCATTCCATTGTTATTAATTGTTTTAATTGTTAATTTTTTGTTTTGTTTAATTTTTATGTTTGTTTTGTTTGGGTCAATTAAGTCTGGTTTAATCCCATGTAAACAGCTCCTTTAGAAATATTATTCCCAGAAAAAACATGATGTGTTCAATACTTATCTTCCCTGCTGTATTTAATATTAGCATTTAATAATAATATTTTAGTGACTAGACAGCATTTCTGATTCGTACCAACAGGTAATTGCCAGTGTTTTGCGGAACCTCTCATGGCGAGCTGATGTGAACAGTAAGAAGATTTTGCGAGAAGTAGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6136
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000044432 Nonsense 1293 2755 16 16
Genomic Location (Zv9):
Chromosome 10 (position 1916178)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 1860041
GRCz11 10 1887755
KASP Assay ID:
554-3691.1 (used for ordering genotyping assays)
KASP Sequence:
CAACTTTACCTATATCAGAAAAACAATCCACTAATAATGTTGCAGCTGAC[C/T]AACGCACATCTGAGAGCCAATCATCAGTCCATTATGTTCGCGCCAAGCCT
Long Flanking Sequence:
AAGAAGAACAGCTCGAGGAACAAACTCCCAGCTACAGCATGAAATACACTGAGGATCATCATGTAGAGCAGCCTATTGATTACAGTTTGAAGTACTCGGAAGCTCCTTCCAAGAAGGGCATGTTTAGTCATTCAAAGACGTCTTCTGCACAGAGTTCTGCCAAAGAACATTTAAGCCAGGATAGTTCTTCTTCTGTGGCATCTTTAAAGAATCAGGGCAGGCAAAAGCAGCTCCACCCTTCATCTGCTCAAAGCAGATCCGGACCAACAAGAGCAGTTCAAAAGAACCCAACATGCAAGGCTCCCACAATAAATCAAGAAACTTTACAGACCTATTGTGTGGAAGATACTCCCATTTGTTTTTCACGTGGTAGCTCTTTATCGTCGTTGTCTTCAGAGGAGGATGAAATGGAGAGCTGTAAGCGTAATGTCAACTCGGCCAGTAACTACCCAACTTTACCTATATCAGAAAAACAATCCACTAATAATGTTGCAGCTGAC[C/T]AACGCACATCTGAGAGCCAATCATCAGTCCATTATGTTCGCGCCAAGCCTCCACGACATCATTTAGGACATGGTGATGGTTCCAGGCATCATAAAACGGTGGAGTTTTCATCAGGGGCTAAATCACCTTCTAAAAGTGGTGCCCAAACACCTAAAAGTCCCCCTGAGCATTATGTACAGGAGACTCCTCTAATGTTCAGCAGATGCACTTCAGTCAGCTCCCTTGACAGTTTTGAGAGTCATTCCATTGCCAGTTCTGTGCAGAGTGAGCCATGCAGTGGGATGGTCAGTGGCATCATCAGTCCGAGTGACTTACCTGATAGTCCTGGACAAACAATGCCTCCAAGTCGCAGCAAGACACCACCACCTCCACCTCCGCGGTCCACGTCAGTAAAACAGAAAGTTACAGTGCCACCCCACACTGAAAAACATGATTTGGCGCCAAGACATGCAGTTGTAAGTGCTGCCGTGCAAAAAGTGCAAGTTTTGCCAGATAATGAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa61
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000044432 Nonsense 1595 2755 16 16
Genomic Location (Zv9):
Chromosome 10 (position 1917084)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 1860947
GRCz11 10 1888661
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTGCAAACCGAGTCAGCTCCCTGTTTATAAATTATTGCCACCACAAAAC[A/T]GAGGGCAACCGCAGAAGCATGTGGCCCTAGCACACGGTGAGGACATGCCC
Long Flanking Sequence:
CAGTGCCACCCCACACTGAAAAACATGATTTGGCGCCAAGACATGCAGTTGTAAGTGCTGCCGTGCAAAAAGTGCAAGTTTTGCCAGATAATGATACTCTTCTACATTTTGCCACAGAAAGCACTCCAGATGGTTTCTCCTGCGCCTCGAGCCTTAGTGCGCTAAGTTTAGATGAACCCTTTATTCAAAAAGATGTTGAGCTGAAGATAATGCCTCCTGTTCATGAGGACGACCATAGTATTGAGGCAGAGCCTGAGATGGAAGATATGCATGAGCCCAAAGTTCAGGAGAAATCACCGGCAACATCTGAAGCTGCAAAAGACATCTTGGATGACTCGGATGATGATGACGACACAGAAATTCTGAATGCTTGTATTAACTCAGCAATGCCAACAAAATCATCAAGAAAACCGAAAAAGCAGTCGACATCAAGGATACCACCACCCGTGGCTTGCAAACCGAGTCAGCTCCCTGTTTATAAATTATTGCCACCACAAAAC[A/T]GAGGGCAACCGCAGAAGCATGTGGCCCTAGCACACGGTGAGGACATGCCCCGTGTGTACTGTGTTGAGGGAACACCCATTAACTTCTCCACAGCAACATCTCTCAGTGACCTCACAATTGATTCTCCTCCGAACGAGTTGGCAGGTATGGAAAGTTCAGCTCCCCATGTAGAAGCATCTGGTCAAAGACGGGACACTCTGCCTGAAGGGAAAAGCGCAGAGGCTAAAGAGACCGGTTTATCACCTCCCATGCAGTCTGCTCTTGCTGAGAATGAAGGAGATGATATTCTTGCTGAGTGTATCAATTCAGCAATGCCAAAAAGCAAAATACACAAGCCGTTTAGAGTGCAGAAGATGCCTGATCAGGCTCAGCATCCATCCACTGCCACTGGCAGTCTAGTTCAGCAGGACCTGGAAAAGAAAAAGCCAACATCTCCTGTAAAACCTATGCCACAAAGTAGTGAATATAGAGCAAGGATGCTCAAACGGCCAGAAGCTAAT
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa21628
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000044432 Nonsense 1900 2755 16 16
Genomic Location (Zv9):
Chromosome 10 (position 1918001)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 1861864
GRCz11 10 1889578
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAAAAAACAGTTTTTCCACAAGCACCCAAAGAAAATACTGTTGTGGTGTG[T/A]GATGAAAAGCAAAAGTTTTCCATTGAAGACACTCCTGTATGTTTTTCAAG
Long Flanking Sequence:
AAGAAAAAGCCAACATCTCCTGTAAAACCTATGCCACAAAGTAGTGAATATAGAGCAAGGATGCTCAAACGGCCAGAAGCTAATAATAGCTTGGCAGATCCAGCAACATATCCAGATAAAAATAAAGAAACCAGAAAGCAAGAACCCAAAGTAGTCATTAGAGACTTTGCTGATAAGCCATCTAATGCTGAGGAGAGGACACGTCCCGGATTTGCCTTCGATTCTCCACATCATTACACACCAATTGAGGGGACACCTTATTGCTTCTCTCGCAATGATTCACTGAGTTCACTTGACTTTGAGGATGAGGATCTTGACTTTTCTAAGGAAAAAGCTGTGCTGCGAAAAGATAAGGAGCAGAGAAAAGTTCCCCTTCTGAAGTGCAGTGTGGAACAGCCAGCAAATACCAACATGGTATCGACATTTCAGACAGCTCCAACAAAACCTCTTCAAAAAACAGTTTTTCCACAAGCACCCAAAGAAAATACTGTTGTGGTGTG[T/A]GATGAAAAGCAAAAGTTTTCCATTGAAGACACTCCTGTATGTTTTTCAAGAAACTCCTCACTCAGCTCACTAAGCGACATTGACCAAGAAAACAACAATAAAGATTGCTCTCACAAAGATGATGTAACTCAAATGGAGGCACCTAGGCCACAAGCGTCTGGTTATGCACCAAAAGCCTTCCACGTGGAGGACACCCCTGTGTGCTTCTCTAGAAATAGTTCCCTGAGCTCTCTCAGTATTGATTCTGAAGATGACCTTCTCCAAGAATGCATCAGTTCTGCAATGCCAAAGAAAAAGAAACAGACACCAAGGAGTAAGACAGAGGAATCCGGGGTAAAGGAAGAAAAGAGCATGATGGCTGATGGTATTTTATCAGAGGAACCAGATCTTATATTAGATCTCACAGACACACATAGTCCTATTTCAGAGCAAGCCTTATCACCAGACTCTGAATCATTTGATTGGAAAGCCATTCAGGAAGGTGCTAACTCTATAGTCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa27530
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000044432 Nonsense 1914 2755 16 16
Genomic Location (Zv9):
Chromosome 10 (position 1918043)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 1861906
GRCz11 10 1889620
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGGTGTGTGATGAAAAGCAAAAGTTTTCCATTGAAGACACTCCTGTATG[T/A]TTTTCAAGAAACTCCTCACTCAGCTCACTAAGCGACATTGACCAAGAAAA
Long Flanking Sequence:
AGTGAATATAGAGCAAGGATGCTCAAACGGCCAGAAGCTAATAATAGCTTGGCAGATCCAGCAACATATCCAGATAAAAATAAAGAAACCAGAAAGCAAGAACCCAAAGTAGTCATTAGAGACTTTGCTGATAAGCCATCTAATGCTGAGGAGAGGACACGTCCCGGATTTGCCTTCGATTCTCCACATCATTACACACCAATTGAGGGGACACCTTATTGCTTCTCTCGCAATGATTCACTGAGTTCACTTGACTTTGAGGATGAGGATCTTGACTTTTCTAAGGAAAAAGCTGTGCTGCGAAAAGATAAGGAGCAGAGAAAAGTTCCCCTTCTGAAGTGCAGTGTGGAACAGCCAGCAAATACCAACATGGTATCGACATTTCAGACAGCTCCAACAAAACCTCTTCAAAAAACAGTTTTTCCACAAGCACCCAAAGAAAATACTGTTGTGGTGTGTGATGAAAAGCAAAAGTTTTCCATTGAAGACACTCCTGTATG[T/A]TTTTCAAGAAACTCCTCACTCAGCTCACTAAGCGACATTGACCAAGAAAACAACAATAAAGATTGCTCTCACAAAGATGATGTAACTCAAATGGAGGCACCTAGGCCACAAGCGTCTGGTTATGCACCAAAAGCCTTCCACGTGGAGGACACCCCTGTGTGCTTCTCTAGAAATAGTTCCCTGAGCTCTCTCAGTATTGATTCTGAAGATGACCTTCTCCAAGAATGCATCAGTTCTGCAATGCCAAAGAAAAAGAAACAGACACCAAGGAGTAAGACAGAGGAATCCGGGGTAAAGGAAGAAAAGAGCATGATGGCTGATGGTATTTTATCAGAGGAACCAGATCTTATATTAGATCTCACAGACACACATAGTCCTATTTCAGAGCAAGCCTTATCACCAGACTCTGAATCATTTGATTGGAAAGCCATTCAGGAAGGTGCTAACTCTATAGTCAGCAGTCTACATCAGGCTGCAGCGAGTCTCTCGAGACAAGGATC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9511
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000044432 Nonsense 2384 2755 16 16
Genomic Location (Zv9):
Chromosome 10 (position 1919451)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 1863314
GRCz11 10 1891028
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGTCTTCAACAAAGTCTAGTGGTAGCGAGTCCGACCGCTCRGAGAAGCCT[G/T]GACTTGTTCGTCAATCAACATTTATCAAAGAAGCACCTAGTCCAACGTTA
Long Flanking Sequence:
GAAGCTCTCCAAGAACCATGAAAGTCCCACCAAGTTCTGAGCCTAGTCCTGCATCTGGTCCACCATCTTCCCAAGGAGGGTCAAGTAAAGCTTCCTCTCGCTCTGGGTCTCGAGACTCCACACCCTCTAGACCAGTTCAGCAATCTCTGACAAGGCCCATGCAGTCTCCTGGTCGTGCCTCTGTTTCACCTGGTAGGAATGGCTTGAGTCCTTCGAACAAATTATCTCAGTTGCCTCAGTTGCCGCGCACTGCCTCTCCTAGTGCATCTTCAACTAAATCTTCAGGATCTGGTCGCATGGCTTACACTTCTCCTGGAAGGCAGTTGGTACAACCAACGCCAACAAAGCAGAGTGGTTTGCCAAGAAGTACAAGTGGAATTCCTAGAAGTGAATCTGCCTCAAAAATCCTAAACCAGTGTGGTCCTTCAAAGAAGGCAGAATTGTCTAGAATGTCTTCAACAAAGTCTAGTGGTAGCGAGTCCGACCGCTCGGAGAAGCCT[G/T]GACTTGTTCGTCAATCAACATTTATCAAAGAAGCACCTAGTCCAACGTTAAAAAGAAAATTAGAGGAATCTGCATCATTCGAGTCCTTATCTCCTTCATCTACAAGCCAGTCACAGACTCCAGTATCTAGTCCTTCCTTGCCAGATATGTCACTTAGTCTACCCTATCAGGGAAGTGGTTGGACAAAGGCCCCTCAGAGTCAGAACTCTGCAGAGAATGGTGACGGCAAGTCACTCAAAAGGCATGACATTTCCCGATCCCATTCGGAAAGTCCTTCCAGGCTCCCAATCAACAGGACAGGCACATGGAAAAGGGAGCACAGCAAACATTCATCTTCTCTCCCAAGAGTTGGCACTTGGAAAAGAACCGGCAGCAGCTCTTCAATTCTCTCCGCGTCTTCTGAATCCAGTGAAAAAGGGAGAAGTGAGGATGAGCGACAACCAACTAACCCACCTCAAAAATCAGGTAAAGAGGGGGGCCTGGAGCGCAAAGGAACATGG
Associated Phenotype:
Not determined