Busch Lab

ZMP

gfra1a

Ensembl ID:
ENSDARG00000058513
ZFIN ID:
ZDB-GENE-010226-2
Description:
Gdnf family receptor alpha 1a [Source:UniProtKB/TrEMBL;Acc:B8JME8]
Human Orthologue:
GFRA1
Human Description:
GDNF family receptor alpha 1 [Source:HGNC Symbol;Acc:4243]
Mouse Orthologue:
Gfra1
Mouse Description:
glial cell line derived neurotrophic factor family receptor alpha 1 Gene [Source:MGI Symbol;Acc:MGI:

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa14181 Nonsense Available for shipment Available now
sa42179 Nonsense Mutation detected in F1 DNA Not yet available
sa22274 Nonsense Available for shipment Available now
sa9341 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa14181
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081395 None None 97 2 3
ENSDART00000124769 Nonsense 40 471 2 22
Genomic Location (Zv9):
Chromosome 13 (position 20656756)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 20387108
GRCz11 13 20518090
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTTTTCTAGCTCWAACCGGCTGGACTGTGTGAAGGCGAACGAGCTGTGTT[T/A]GAAGGAGCCGGGATGCAGCTCAAAGTATCGARCTATGAGGCAGTGCGTGG
Long Flanking Sequence:
GAGTTGTTATTTACACATTGTGTTCACTGAAGACTGAAACTCAAAGAATATTTAAAAAGTGTTTATCCCACCGGGTCCCATCACATTTATTCTAGTCTAAAACAGTATATTCTGAAATGTTATAGATCTAGAATGTTATGTCTCATAATAGGACACAGTTTTGTTATTGAGGATCAGCTTTGTTTTTACTTTAATCTTAATCTTCTTGTGTTAATATTTTAGTCTCTAAAACACCATTTTACCTCACAAAATGTTTCCATGCATTAAACAATATTTGTAATTTAAGTAGCCTGGTTCATGCAAAATAAAATCCACAACTTTTATTATTTTATTATTATTATTATTATTATTATTATTATTATTATTATTATGTAAGTTTGAGTAGCCTAGTTGATGATTATTTCCATTGTTGTCCTATATAGATGTGCTGTTATCTGCCGAGGAGTCTTACTTTTCTAGCTCTAACCGGCTGGACTGTGTGAAGGCGAACGAGCTGTGTT[T/A]GAAGGAGCCGGGATGCAGCTCAAAGTATCGAACTATGAGGCAGTGCGTGGCGGGGAGGGAGTCCAACTTCAGTATGGTGACTGGAATGGAGGCAAAGGATGAATGTCGACTTGTCTTGGACGCTTTAAAGCAGAGTCCTTTGTATAACTGCCGCTGCAAAAGAGGGATGAAGAAGGAAAAGAACTGCCTGCGCATCTACTGGGGGATCTATCAGCATTTACAGGGTGCGCAGCCTTGCCTTCTCATATGATATAAACATATGAAGTATTCAGCTTCTTCACAACATAGTTTTCGACAGTTTATTTTTAATACTTGGCGACCAAAATCAGTAGTCAAGGAGTTGCTTTTTTGGTTTGTGCTATCAGATAGGGTGACTGTAAAGTCTTCAAATGCCTGTCTGAAGTGTGTCCATTAAAGTTTATGGAGTGTGAGGTCATCTGATGCTTTATGTTAGTGTATATGTGCCTGCTAGAGGGGGAGCAGGAACTTTGCCAGCTCAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42179
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081395 None None 97 2 3
ENSDART00000124769 Nonsense 49 471 2 22
Genomic Location (Zv9):
Chromosome 13 (position 20656728)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 20387080
GRCz11 13 20518062
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGAAGGCGAACGAGCTGTGTTTGAAGGAGCCGGGATGCAGCTCAAAGTA[T/A]CGAACTATGAGGCAGTGCGTGGCGGGGAGGGAGTCCAACTTCAGTATGGT
Long Flanking Sequence:
GAAGACTGAAACTCAAAGAATATTTAAAAAGTGTTTATCCCACCGGGTCCCATCACATTTATTCTAGTCTAAAACAGTATATTCTGAAATGTTATAGATCTAGAATGTTATGTCTCATAATAGGACACAGTTTTGTTATTGAGGATCAGCTTTGTTTTTACTTTAATCTTAATCTTCTTGTGTTAATATTTTAGTCTCTAAAACACCATTTTACCTCACAAAATGTTTCCATGCATTAAACAATATTTGTAATTTAAGTAGCCTGGTTCATGCAAAATAAAATCCACAACTTTTATTATTTTATTATTATTATTATTATTATTATTATTATTATTATTATTATGTAAGTTTGAGTAGCCTAGTTGATGATTATTTCCATTGTTGTCCTATATAGATGTGCTGTTATCTGCCGAGGAGTCTTACTTTTCTAGCTCTAACCGGCTGGACTGTGTGAAGGCGAACGAGCTGTGTTTGAAGGAGCCGGGATGCAGCTCAAAGTA[T/A]CGAACTATGAGGCAGTGCGTGGCGGGGAGGGAGTCCAACTTCAGTATGGTGACTGGAATGGAGGCAAAGGATGAATGTCGACTTGTCTTGGACGCTTTAAAGCAGAGTCCTTTGTATAACTGCCGCTGCAAAAGAGGGATGAAGAAGGAAAAGAACTGCCTGCGCATCTACTGGGGGATCTATCAGCATTTACAGGGTGCGCAGCCTTGCCTTCTCATATGATATAAACATATGAAGTATTCAGCTTCTTCACAACATAGTTTTCGACAGTTTATTTTTAATACTTGGCGACCAAAATCAGTAGTCAAGGAGTTGCTTTTTTGGTTTGTGCTATCAGATAGGGTGACTGTAAAGTCTTCAAATGCCTGTCTGAAGTGTGTCCATTAAAGTTTATGGAGTGTGAGGTCATCTGATGCTTTATGTTAGTGTATATGTGCCTGCTAGAGGGGGAGCAGGAACTTTGCCAGCTCAACTGACCAGGATAACTAATCAACCAGAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22274
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081395 Nonsense 24 97 2 3
ENSDART00000124769 Nonsense 75 471 2 22
Genomic Location (Zv9):
Chromosome 13 (position 20656650)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 20387002
GRCz11 13 20517984
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGGGAGTCCAACTTCAGTATGGTGACTGGAATGGAGGCAAAGGATGAATG[T/A]CGACTTGTCTTGGACGCTTTAAAGCAGAGTCCTTTGTATAACTGCCGCTG
Long Flanking Sequence:
ATATTCTGAAATGTTATAGATCTAGAATGTTATGTCTCATAATAGGACACAGTTTTGTTATTGAGGATCAGCTTTGTTTTTACTTTAATCTTAATCTTCTTGTGTTAATATTTTAGTCTCTAAAACACCATTTTACCTCACAAAATGTTTCCATGCATTAAACAATATTTGTAATTTAAGTAGCCTGGTTCATGCAAAATAAAATCCACAACTTTTATTATTTTATTATTATTATTATTATTATTATTATTATTATTATTATTATGTAAGTTTGAGTAGCCTAGTTGATGATTATTTCCATTGTTGTCCTATATAGATGTGCTGTTATCTGCCGAGGAGTCTTACTTTTCTAGCTCTAACCGGCTGGACTGTGTGAAGGCGAACGAGCTGTGTTTGAAGGAGCCGGGATGCAGCTCAAAGTATCGAACTATGAGGCAGTGCGTGGCGGGGAGGGAGTCCAACTTCAGTATGGTGACTGGAATGGAGGCAAAGGATGAATG[T/A]CGACTTGTCTTGGACGCTTTAAAGCAGAGTCCTTTGTATAACTGCCGCTGCAAAAGAGGGATGAAGAAGGAAAAGAACTGCCTGCGCATCTACTGGGGGATCTATCAGCATTTACAGGGTGCGCAGCCTTGCCTTCTCATATGATATAAACATATGAAGTATTCAGCTTCTTCACAACATAGTTTTCGACAGTTTATTTTTAATACTTGGCGACCAAAATCAGTAGTCAAGGAGTTGCTTTTTTGGTTTGTGCTATCAGATAGGGTGACTGTAAAGTCTTCAAATGCCTGTCTGAAGTGTGTCCATTAAAGTTTATGGAGTGTGAGGTCATCTGATGCTTTATGTTAGTGTATATGTGCCTGCTAGAGGGGGAGCAGGAACTTTGCCAGCTCAACTGACCAGGATAACTAATCAACCAGAAACTGGCTCCGGAAATGTAAACCAGTCTTTATGAATCAGTGACCCAAATACGAACAAACATCACTGTGAAAAATAAAGGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9341
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081395 None None 97 None 3
ENSDART00000124769 Essential Splice Site 409 471 20 22
Genomic Location (Zv9):
Chromosome 13 (position 20530350)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 20270241
GRCz11 13 20401223
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATCTCARCCCKGCTGATAACTCCCTCTACCAGTTCTGTGGTAACATACAG[G/A]TCAGTGGGACTATTGCATATTACACAYATCTTCMACTTTCATGTATGTAT
Long Flanking Sequence:
ATAGATTTTCCATGTTGTAATTTAGGAATAAGATTGCATGTAATTAATGGTTTTATCGATTTTAACTTTTTTTTTTTACTGAGCAGCTCTAGTGTAAGCATTGAATTACAGTAAAACGCATATCTCACGCAAATATTATAACAAATACCTAACAGACTATCAACATGAGTTTTGAACAACAGATAATTGGATCAAACCAACTGGGTTTGTCTCCTAATTCATTAATCGTTCACTGGATCTCTTTTTTTTTAGCAGTGTATATGACAAATACTATCTTTGGTCTTTGTATAAAAGGTAACGCAATCCAGGCGTTTGGAAATGGGACAGATGTGAGCGTCTGGCATCCAATGCCCCCAGTACAAACCACCACCTCTATGACAACACCATCCCAAAGGGCCAGAGATAAAGATAGATCACCCAATGCCATAGAGCCGGCCACACACATCAACCATCTCAACCCGGCTGATAACTCCCTCTACCAGTTCTGTGGTAACATACAG[G/A]TCAGTGGGACTATTGCATATTACACACATCTTCAACTTTCATGTATGTATTGATAGTTTGGTGCATGTGCAGTCAGCATTATTAGCCCCATAAATGATTAGCCCCCTATTTATTTTTTCCCCCATTTTCTGTTAAGCGGAGAGATTTTTACAACACATTTCTAAATATAATAGTCTTAACTCATTTCTAATAACTGATATATTTTATCTTTGCCATGATGACAGTGAATAATATTAGACTAGATATTTTCAAGACAGTTCCATACAGCTTAAAGAGACATTTAAAGGCTTAACTAGAGTATTTGGCTTAACTAGGCAGGTTAGCGCAATTAAATCATTAAATTTATTGTATAACGATACGATGTTCTGTAATGATTTTGACCTTAAAACGGGTTTAAAAAAATAAAGTTAAAAACTGCTTTTATTTAAGCTGAAATAAAGACTTTCTCTTGAAGAAAAAAATCAGACATACTGTGAAAATTTCCTTGCTCTGTTAAACAT
Associated Phenotype:
Not determined