Busch Lab

ZMP

chtf18

Ensembl ID:
ENSDARG00000058480
ZFIN ID:
ZDB-GENE-050522-508
Description:
CTF18, chromosome transmission fidelity factor 18 homolog [Source:RefSeq peptide;Acc:NP_001103572]
Human Orthologue:
CHTF18
Human Description:
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:18
Mouse Orthologue:
Chtf18
Mouse Description:
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) Gene [Source:MGI Symbol;Ac

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa38244 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa18673 Nonsense Available for shipment Available now
sa11678 Nonsense Available for shipment Available now
sa19429 Nonsense Available for shipment Available now
sa5934 Nonsense Mutation detected in F1 DNA Not yet available
sa38245 Nonsense Mutation detected in F1 DNA Not yet available
sa39550 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa38244
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000092058 Essential Splice Site 86 957 2 22
ENSDART00000109177 Essential Splice Site 86 348 2 17

The following transcripts of ENSDARG00000058480 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 8277755)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 8517560
GRCz11 1 9201671
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCAGAGAGCATCTCTCCGCCGGTATACGAGGAGGAAGAGGAGTCTCTGAG[T/C]GAGTGCTTTACATTGGATTTTTACATTTGTGTCATAAAACACATTTTTCA
Long Flanking Sequence:
CAACCAGGCAGTTACGATGTCTGTTAAAGGGTTAAAAAGTTAAACGATCAGCATTTATTAGATAAATTTAACACACTAATTGTTCAGTCTTTAAATGTAAGAAAATGGACCCTTGCTAAATAAAATAATTTCTTAACCCCCCCCCCCAAATACCTAATAGACACATAGATAGATAGTTTGATGTTTTTTTTCTATTTTTTGTAGCTTATCAACAAATTACAATATCAAGTTTAACAATAATCTCTTTTCTGTTGTAACTTATTTGTAAATAAACACATAAAATAATTAAATTAGTTCATTCATTTAAATGCATGAATGTATCTGTGTGTAGGCAACAATCCACCAGCTGCAAAAGTGTCTGAATTTCGCAATAAGCCGATCACACAGACGTTCGAGGAAGCCCTTGTGTCCGGAGACCAGCCATCAAGGAAATCAGTAAATAACCAGAATCCAGAGAGCATCTCTCCGCCGGTATACGAGGAGGAAGAGGAGTCTCTGAG[T/C]GAGTGCTTTACATTGGATTTTTACATTTGTGTCATAAAACACATTTTTCATTCAGAAGGTTGGGATATGTGCGCTTTTTAATTCTCACTGAATGATTCAGTCAAAATAGTAATGTTAAGTTTTATAACAAACTAAAATAGTGCTGCCCGATATTGGAACATTTTTATTTATTTCATAAATAAATAATTTATTTAAAAATGTATTTATTTATTTAGTAATAGTTTTTTGTGTGATTAAATATTGCGATATGAAAACAGTTTCAGGAGATAGTTTAAAAGGCACTATTTGACATTTTTTGGGAAGCCTAACAGTATTCAGATACAGAAATTAAATAATCAAAATGCAAAAAATAAATAAAAAATGCTTTTCTTACTTTCATTTGTCTCGTTTCTAGTCCAAATATCAAAAAATTCTCAGATGAAAATAAACTATTGTTTTCAGCAAAATTAAGTTACCTTAAAACAAGTAAAATTTATCTGCCAGTGGGGTAAGTAAAATAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18673
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000092058 Nonsense 94 957 3 22
ENSDART00000109177 Nonsense 94 348 3 17
ENSDART00000092058 Nonsense 94 957 3 22
ENSDART00000109177 Nonsense 94 348 3 17

The following transcripts of ENSDARG00000058480 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 8279172)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 8518977
GRCz11 1 9203088
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGTAGTATRAAGTTTGACTTCTCACAGCYCCTAAACCCAAGAAAAGGAGG[C/T]AAGATGTGGCGAAAAAGCTCCAGTTTGGCGTTGACCAAGATGATGACATC
Long Flanking Sequence:
AGCCAGTCACACAGCAGAAATGTGCAACAGTGAAAATCTAAAAGTTTTTTTGTGAAAACCACAAAAGTATTGGCCAACATAAATAGGTCATGTTATTTAATGGACCCTCTAATTTGTGGCTTCAGTTATTGTTGGTATACTCTTTTAAATCTGGAAGCATTAACAACTGATGTCAAAATATATATTGTTATTGTTTAATATAGAAAAAATTAATCAAGATTGCATTTTTGCCATATCACCCAGCCCTACTTTAAGCAAATTTAGAGTGTTATTTTTTTATTTAATGTTTAAAAAATTATTTTAATAATGTTAAAAAGTCAAATGATCATCATTTATTTGAATTTTTGTAACATTCTATTTGTCTTGAATTGTAAACATTCTTTAGTCTTAAAATGAAAAAGAATTCATTTCTTAACCTCAAAAATACCTACAAGCATTTGAAGAGGATTGTGTAGTATGAAGTTTGACTTCTCACAGCCCCTAAACCCAAGAAAAGGAGG[C/T]AAGATGTGGCGAAAAAGCTCCAGTTTGGCGTTGACCAAGATGATGACATCACTCCTCCATCTTCCCCAGAGGTTTACGACAGGGAAGTGAGAGACGGGTAAATATTTATGCACATTTATACCATATTTAAAATGTACCACTGAATGGAAGCGTTGGTTTTTGATCTTTTTTTTTTTTTTTCACAGGCCTAGATTTTCCCTAACCCTGAGTCCAGACAGACCAGCAGCAACAAAAATAACGACAAATGTTTTAGATATTAGTGGACTGGGAGCTTTACAGGAGTCACCGAAGCAGGTGACGGCAGCAAAACGTCATGCTCAGAAACGCCCACCTGCAATCGGAGATTACATCACAGTCACAGACTCTATGGGAAACAGGGTCTACCTTAACAAGAAAGAGGATGTGGAGAAGGTTTTATTCCATATTAACAACTTAACTTCACAGCTTACAGAAGTGCAATACGTAAAATATAATGGTTGATGTATTTATCATTTTTCTCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa11678
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000092058 Nonsense 94 957 3 22
ENSDART00000109177 Nonsense 94 348 3 17
ENSDART00000092058 Nonsense 94 957 3 22
ENSDART00000109177 Nonsense 94 348 3 17

The following transcripts of ENSDARG00000058480 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 8279172)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 8518977
GRCz11 1 9203088
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGTAGTATRAAGTTTGACTTCTCACAGCYCCTAAACCCAAGAAAAGGAGG[C/T]AAGATGTGGCGAAAAAGCTCCAGTTTGGCGTTGACCAAGATGATGACATC
Long Flanking Sequence:
AGCCAGTCACACAGCAGAAATGTGCAACAGTGAAAATCTAAAAGTTTTTTTGTGAAAACCACAAAAGTATTGGCCAACATAAATAGGTCATGTTATTTAATGGACCCTCTAATTTGTGGCTTCAGTTATTGTTGGTATACTCTTTTAAATCTGGAAGCATTAACAACTGATGTCAAAATATATATTGTTATTGTTTAATATAGAAAAAATTAATCAAGATTGCATTTTTGCCATATCACCCAGCCCTACTTTAAGCAAATTTAGAGTGTTATTTTTTTATTTAATGTTTAAAAAATTATTTTAATAATGTTAAAAAGTCAAATGATCATCATTTATTTGAATTTTTGTAACATTCTATTTGTCTTGAATTGTAAACATTCTTTAGTCTTAAAATGAAAAAGAATTCATTTCTTAACCTCAAAAATACCTACAAGCATTTGAAGAGGATTGTGTAGTATGAAGTTTGACTTCTCACAGCCCCTAAACCCAAGAAAAGGAGG[C/T]AAGATGTGGCGAAAAAGCTCCAGTTTGGCGTTGACCAAGATGATGACATCACTCCTCCATCTTCCCCAGAGGTTTACGACAGGGAAGTGAGAGACGGGTAAATATTTATGCACATTTATACCATATTTAAAATGTACCACTGAATGGAAGCGTTGGTTTTTGATCTTTTTTTTTTTTTTTCACAGGCCTAGATTTTCCCTAACCCTGAGTCCAGACAGACCAGCAGCAACAAAAATAACGACAAATGTTTTAGATATTAGTGGACTGGGAGCTTTACAGGAGTCACCGAAGCAGGTGACGGCAGCAAAACGTCATGCTCAGAAACGCCCACCTGCAATCGGAGATTACATCACAGTCACAGACTCTATGGGAAACAGGGTCTACCTTAACAAGAAAGAGGATGTGGAGAAGGTTTTATTCCATATTAACAACTTAACTTCACAGCTTACAGAAGTGCAATACGTAAAATATAATGGTTGATGTATTTATCATTTTTCTCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19429
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000092058 Nonsense 337 957 8 22
ENSDART00000109177 Nonsense 337 348 8 17

The following transcripts of ENSDARG00000058480 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 8282665)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 8522470
GRCz11 1 9206581
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCCGTCCGGTCCCTGTAGAGGCCAGATCAAATTTTACAAACGCTCAAAAT[C/T]AAAACCAGGCCCAACGTTTCAAAACCAAGTCTCAAATGACAGAAGAGATA
Long Flanking Sequence:
ACTATGATAAAGTAAATTCATTTATGTGTGTTCTGCAAAGTCCTTAACAAAAATCCATCCTAGACCTGGCTTCCAAAAGCAAGAAAGCATGACAATATCTAAATCTGTGTTTTATCTTCTGCTTTGACTGAGGCACAACTAATTTACTATGGAGTTAAATAGTTTGAATATAATGAGTTAAAAAACATAAACTTTATTATTGATATACCATACTAGTTTCCTTGTGTGTTGGAAACTGTGCTTTATTTGCAAATATTTTATGTTAGATTAGAATTTTTACTTTAAATGGAGTCATAGATGTGCTGTTTATTCAAACCCGTTCTGGTTAATTAGTATCCATCAGTTTTGTTATTATTTACATTGTCTCTGTATTCCTGTAGTTTACTAATCGCTGTCTGCTGAAATGGCTGAAGCTCTGGGACACTGTGGTCTTCGGGCGAGAGAGGAAAAGCCGTCCGGTCCCTGTAGAGGCCAGATCAAATTTTACAAACGCTCAAAAT[C/T]AAAACCAGGCCCAACGTTTCAAAACCAAGTCTCAAATGACAGAAGAGATACTAGAGGCTGAGCTAGACCAGTACAAAAGACCGAAATTTAAGGTGAGTGCAATTGCGCAATTACAATATTGTTAAATTTGTTTTTTATTATTCGATTTTTAAAATATAAATATATATATATATTTTTTTTTTATTTTGTAATATTTTTATTTATTCATTTAATATTTGTGTCTGCTTCCCCTGTATTTTTTGAGAAAAAAATTAATAATAAATTAAAAAAAAATAATCTATATATATATATATATATAATTTTTTAAAAATATTTTAAAGATTATTTTTTAAAAATAAAATAAAAAAATAAAAATAGAGTTAATCATTTCTGATGTAAATTGTTTTTGTATTGTCTAAAATAATATAATTATCTGAAACCATTGTACCTTTTTATCTTTTTATTTTGTGCAAAAAAATATTTTTATTGTTTATTTAGGAAGTAATAGCATCACTTTCAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa5934
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000092058 Nonsense 562 957 14 22
ENSDART00000109177 None None 348 None 17

The following transcripts of ENSDARG00000058480 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 8285959)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 8525764
GRCz11 1 9209875
KASP Assay ID:
554-3758.1 (used for ordering genotyping assays)
KASP Sequence:
TGCTCATGCTATCTGTGTGCAGTTTTTACACAGTCGTGGACAGAAGCACT[T/A]GGACCAGCGCAGTGTCAGCTCCATGTGTGTGGGATTGAAAGACCAAAACA
Long Flanking Sequence:
ACCCAACTTTGAGAATAGATTAACGGAGATATTCTCGTGTTAACGCAGCACTTTAACGGCGATAATGTTACCACCGCTAAAAAATATAAAAATTTCCTGTTTTTGTACTTTTCATCAGATATGTTCCAGCTCTAAGGCCACTGAGACAGCAAGCTTTCCTGCTGGTCTTTCCTCAGACTCTGCCATCACGCTTGGCTCAAAGATTAGCAGAGGTGACAGACACACACACACACACACATTCACACAATGATTTCATAAACTCATGAATGGTGACTTACGCAAGCTTTTGTTTCTATGTGTAGATCAGCAGGCGTCAGGGAATGAAAGCAGATACAGGCACTCTGATGGCCCTGTGTGAGAAAACTGACAATGACATCCGTTCTTGCATCAACACATTACAGGTGAGAGAGATATCTGGTGCTTTAAAATATTTCACAGTTAACACGGGTTTGCTCATGCTATCTGTGTGCAGTTTTTACACAGTCGTGGACAGAAGCACT[T/A]GGACCAGCGCAGTGTCAGCTCCATGTGTGTGGGATTGAAAGACCAAAACAAGGGACTGTTCTCAGTTTGGCAGGAGATCTTTCAGCTTCCTCGACTGAAAAGGTACACAACTGTCACATGCTTTTTCACTCTTCAGTCTGCCCTGCGCAGCTTTTCCGTTTGAGAAATTAATAAATAGTCATAATAAGGTCATGCTATTAAAATACTGTTTCAAAAAAGAATCTTATATTTTTGAACTTGTTGGTTTTTATAAGTTCTTATTGGAAAGACATAATTACATTATTTGCATTTATGTTTTTACGAAATAATTTGTCATACTGGTTAACAAAATATCTACATATATCCACCTACTCAATAAACAATACACGCAACCTCTCTATTAGGGTTGGGCCGATAGATGATGCCATTGTTCATCGCCGATGGCCAACAGACACCACGATGCTGAGCCAGCATCGCGATCCTCCGCCTCGCCCCCTTTGCAAATCCGCTCACGAAAAATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa38245
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000092058 Nonsense 580 957 14 22
ENSDART00000109177 None None 348 None 17

The following transcripts of ENSDARG00000058480 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 8286012)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 8525817
GRCz11 1 9209928
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACCAGCGCAGTGTCAGCTCCATGTGTGTGGGATTGAAAGACCAAAACAAG[G/T]GACTGTTCTCAGTTTGGCAGGAGATCTTTCAGCTTCCTCGACTGAAAAGG
Long Flanking Sequence:
TAACGGCGATAATGTTACCACCGCTAAAAAATATAAAAATTTCCTGTTTTTGTACTTTTCATCAGATATGTTCCAGCTCTAAGGCCACTGAGACAGCAAGCTTTCCTGCTGGTCTTTCCTCAGACTCTGCCATCACGCTTGGCTCAAAGATTAGCAGAGGTGACAGACACACACACACACACACATTCACACAATGATTTCATAAACTCATGAATGGTGACTTACGCAAGCTTTTGTTTCTATGTGTAGATCAGCAGGCGTCAGGGAATGAAAGCAGATACAGGCACTCTGATGGCCCTGTGTGAGAAAACTGACAATGACATCCGTTCTTGCATCAACACATTACAGGTGAGAGAGATATCTGGTGCTTTAAAATATTTCACAGTTAACACGGGTTTGCTCATGCTATCTGTGTGCAGTTTTTACACAGTCGTGGACAGAAGCACTTGGACCAGCGCAGTGTCAGCTCCATGTGTGTGGGATTGAAAGACCAAAACAAG[G/T]GACTGTTCTCAGTTTGGCAGGAGATCTTTCAGCTTCCTCGACTGAAAAGGTACACAACTGTCACATGCTTTTTCACTCTTCAGTCTGCCCTGCGCAGCTTTTCCGTTTGAGAAATTAATAAATAGTCATAATAAGGTCATGCTATTAAAATACTGTTTCAAAAAAGAATCTTATATTTTTGAACTTGTTGGTTTTTATAAGTTCTTATTGGAAAGACATAATTACATTATTTGCATTTATGTTTTTACGAAATAATTTGTCATACTGGTTAACAAAATATCTACATATATCCACCTACTCAATAAACAATACACGCAACCTCTCTATTAGGGTTGGGCCGATAGATGATGCCATTGTTCATCGCCGATGGCCAACAGACACCACGATGCTGAGCCAGCATCGCGATCCTCCGCCTCGCCCCCTTTGCAAATCCGCTCACGAAAAATACACAATCAGGCCCTGTTTACACTAATAGGTCTTATTTTTTAAAATGGCATTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39550
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000092058 Nonsense 802 957 18 22
ENSDART00000109177 None None 348 13 17

The following transcripts of ENSDARG00000058480 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 8294241)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 8534046
GRCz11 1 9218157
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TACAACCTGACCTACAGACAGGACCGAACGCCAGAGGGACAGTACACTTA[T/A]GTGCTGGAGCCGTGAGTACATGCGCATACATGAGCAACATCATCTTGATC
Long Flanking Sequence:
ATCCCTTCCTATTTGCCCGCTGAGTCTGTGCATCTCTATTTGAAATAATGAAACTGAGCATTTAAAAGACGCTATACATGAAAGTCCCCTTTCGTTGACTGGCATTATCAGACCTGCACATTAAAAGGCCCTGTTTGCGGTTGTATTTAAATTAATAAATACTTCAGGCAGTCTGAACAAAGAAGTCCAGTGAGCTGTATTGTGAGTGAGTAGATGCTGAGGAACGTTTTGGGTGAGCTACTCATTTAAGCAGCACATTCCTCTACAACATTGATAATAAATGAAATCCACTTTTGACATCACAGAAGAAAATCACAATTAAAAATGTAATTGTTCTCAATGTTACTGTTTTTACTGTATTTAACTGTGTCTGTCATGCAGGTGAACCCTCAGCTTTACAGCACCAGGGAGAAGCAGCAGCTCTATGATCTGATCGACACAATGATCAACTACAACCTGACCTACAGACAGGACCGAACGCCAGAGGGACAGTACACTTA[T/A]GTGCTGGAGCCGTGAGTACATGCGCATACATGAGCAACATCATCTTGATCTGCAGAGTCATTCAACACAATGTTTTTATTTTGAGACAGAGAGCTTCATGCTTTCCTGTTATGCAACTCAGACTTCATTACAGGAATAAACTCCAACACTCGCACACACTGAGTCACACTATGTGTTCACCCGTCTATCACGATTTATGAGAGATTAGGCTGCGGCTGCAGATTATAGTCTCCCTCTCTTTCTCGTCTAATTTTTCTTTTATTTTCTGTCTGCTCTGGCATTTCTCTCTGTTGAGAACTTGGGGTTTTTGTGTTGCATGCCTTTGAAAGTCATGCATGGATTCACACGTTCATCACTCAAGCATATAAAAAAATCCTGCAATCCTCTCTGGCTTACTGAGACTGAGTCCTAGCACTCACACTGATTGATGAAGTGATGCTGAAAATGTTCACAATTGAGCCTTCAATGCCCACCGGTGGAGTTAAAGTCTGTTTGGTGGA
Associated Phenotype:
Not determined