ZMP
plk1
Ensembl ID:
ZFIN ID:
Description:
serine/threonine-protein kinase PLK1 [Source:RefSeq peptide;Acc:NP_001003890]
Human Orthologue:
PLK1
Human Description:
polo-like kinase 1 [Source:HGNC Symbol;Acc:9077]
Mouse Orthologue:
Plk1
Mouse Description:
polo-like kinase 1 (Drosophila) Gene [Source:MGI Symbol;Acc:MGI:97621]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa19428 | Nonsense | Available for shipment | Available now |
| sa10264 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa19428
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000081343 | Nonsense | 295 | 595 | 5 | 11 |
The following transcripts of ENSDARG00000058471 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 1 (position 8232354)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 8472159 |
| GRCz11 | 1 | 9156270 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGACCTTCTGTAGCTGAACTGCTGACTGATGAGTTTTTCACCTCTGGTTA[T/A]GCACCCATGCGGCTGCCCACTTCCTGTCTCACTGTTCCTCCCAGGTTCTC
Long Flanking Sequence:
TGTCAAAAAATTGAATCAAAGTTGTCATTTCCATTATTTTACTTGCTCTGCTGTGCAGGATATTTTCATTTTAGCAGTACATTTGTTTGTAGCACCCCCAAATGTCATCTAAAGTGAGTTAAAAAAATAACAGTAGGGAAGGGTATGAGTTTTAGGAAAACTGGTCACAAGAATAATTGAATGCTGGTTACTATCAGATTGAAATGTAATTAATCTTTAGCTGACCACTTGAGATTGGATCACTGAGAGCACAATATATCTGAAAATTGATTGATTTAATACCATCTGGAATTTGTAGCTTCTAATGTGGAATGCTTAACCCATTTATACAAGCTTAAACATGAAAAACAGATTGGTGACTTATTACATTGTTGGTGGTTTTTTTTTAAGCACATTAATCCAGTTGCATCTGCTTTGATTCGTCGGATGCTGCACGCTGACCCTACACTCAGACCTTCTGTAGCTGAACTGCTGACTGATGAGTTTTTCACCTCTGGTTA[T/A]GCACCCATGCGGCTGCCCACTTCCTGTCTCACTGTTCCTCCCAGGTTCTCCATCGCCCCCTCCAGCCTGGATCCTGCCCTCCTCCGCAAACCTCTCTCATCACTTAATAAAGGTATACAAGTGTTTTTATTATTTTATTATAATTTTTTATATATTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAAGACCATTTTAATGTGGTCATGTCATTGTGCCATGAACATTTCCTGCTTAAACTTTTATAGCCGTAACGAGGCAATTCAATCATAACTTGATGTTAAAACAGCTATCATAGCATTATTTATCAATATGTGGATCTTTTTGGAAGCATGAGAAATTAAAACTGTAAGACAAGAAATGCGTTGACACCATTGTGTTTTGTTTGCATCCCTCAAAATGGTTAATAGTCTTAGTGCATTCTTTATTAATCGAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa10264
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000081343 | Nonsense | 458 | 595 | 9 | 11 |
The following transcripts of ENSDARG00000058471 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 1 (position 8234424)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 8474229 |
| GRCz11 | 1 | 9158340 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCTGCAGTACATCGAYCGCAACTCTYTAGAATCCTACCTCAGTGTTYGCT[C/A]GTATCCCTCTGCACYCTCCAAAAAGGTCTGCATGGTTCTGGNAAKAAWGT
Long Flanking Sequence:
CCCAGAGATTGTTGTGTACACTGACTATATATAAAATTAAATTATGTGTAATATGAATAAAAAGTGATCATAAACGAATGATTTCTCAAGTCAAATGAGTGACTGCTTGGACCTGGAAACAATATTAAATGCGTCACAACTTAACAAGTGGATTGAAACATCCCACCTGTTGAATGGTAATCTTTAAGAGTGAGATAAAATAATGGTTTGCGGAGCCTTCCAATTGATAAGTATAATTAAAATAATGATACAAGTATGATTTGCAGCATCTGATAGTGCCAAATCTAACACTTTTTTTTTTTTTGTTGTTGTTTTTTTTTTTTGGAAAATACTGCCACTTATGCAAATGTTTATTTATTTTTTTTTATTAGGTTACCAGTTGTCTGATAACAGTGTAGGTGTTCTGTTCAATGATTCCACACGGTTGATCATGTGTGCTGACGGTGATAGCCTGCAGTACATCGATCGCAACTCTCTAGAATCCTACCTCAGTGTTCGCT[C/A]GTATCCCTCTGCACTCTCCAAAAAGGTCTGCATGGTTCTGGAAATAATGTGTTGGATAAGTGACACTGATTTGATGTCCAGAACTAACATACTGTCTTTATTTTAGATTACACTCCTTAAGTACTTCAGGAATTACATGAGTGAGCACTTGCTGAAGGCTGGAGCGAATATAACTCCTCGGGAAGGGGATGAACTGACCCGATTGCCTTACCTTCGCCACTGGTTCCGCACAAAGAGTGCTATTGTGCTACACCTGAGTAATGGGACTGTGCAAATCAATTTTTTCCAGGTAAGAATGCTGCGTAACAATCTTGTATTAATCTAAAGCATTTGTCAGTATTAAATTTATCCATTTATAGACCATTTTCAGTGTGGTCATGACATTGGCCCATGAACATTTGCTGCTTGGTATCAAACTACTTCATAACTGTAGCGAGGCAATACAATCATAACCTAGTGTTAAAACAGCCATCATAACATTTATCCATATGGGATTCTCA
Associated Phenotype:
Not determined