ZMP
tph2
Ensembl ID:
ZFIN ID:
Description:
tryptophan 5-hydroxylase 2 [Source:RefSeq peptide;Acc:NP_999960]
Human Orthologue:
TPH2
Human Description:
tryptophan hydroxylase 2 [Source:HGNC Symbol;Acc:20692]
Mouse Orthologue:
Tph2
Mouse Description:
tryptophan hydroxylase 2 Gene [Source:MGI Symbol;Acc:MGI:2651811]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa8576 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa8576
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000079832 | Nonsense | 160 | 500 | 4 | 11 |
| ENSDART00000112627 | Nonsense | 133 | 473 | 4 | 11 |
Genomic Location (Zv9):
Chromosome 18 (position 16657636)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 18 | 17009402 |
| GRCz11 | 18 | 16998468 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CAGACTGTTTGGACTGTGTGTGTGTTTTGGGTGGATTGCCAGATGGGGAA[G/T]GAATACCATGGTTTCCCCAAAAAATCTCAGAGCTGGATCAGTGCTCCCAT
Long Flanking Sequence:
TGGGAAGCTGGCAGTGATTTTCTCTCTGAAGAATGAAGTTGGCTTTCTGGTGAAAGCGCTGAGGCTCTTTCAGGTCAGTGTGCACCTCATCATTTGGTGCATAAATAATATTTGTGTCTTTTTGATTGAGAAAAGCAAGAATCAAATGTCTTTGCGTGCTTGTGTTTAAAGGAGAAGCATGTGAATTTGGCGCACATTGAGTCTCGGAGATCAAAGAGACTCACCAATGAGATTGAGATATATGCAGAATGCAACTGCACAAAGAAAGAGTTCAACGAACTGGTGCAACACCTCAAAGACCACGTTAATATTGTCTCGTATAACACACCTCAACATGTGTGGTCTGCAGAGACCGGTAAGTCTGAAAGCTTGACATTAAATTTGGGATTTTGAGTGTGGAGGTACTGATTGGTCTGAATAGTGGTAACTGATTCATCTGGCTCTTCTTTCCAGACTGTTTGGACTGTGTGTGTGTTTTGGGTGGATTGCCAGATGGGGAA[G/T]GAATACCATGGTTTCCCCAAAAAATCTCAGAGCTGGATCAGTGCTCCCATAGAGTGCTAATGTATGGCTCTGAACTGGATGCTGATCATCCAGTAAGTTAATATGTTTGTGTCAGTGCAATAGTTGAGTGAATGGACCTCAAAACATTTACTGTCAACTCTGAAATTTAACCATGTTTTTTCTACAATACCACTAGTTCAAAAATGGTATTTGTGGTAAAATGTGGGTAATCACTTTGCCCTTAAAAAACGTGGTTACTACATTTTTATCATTGTAAAATCATGGTTCATTTTCCATAAGGGATATCTAAAGATTGACAAGGACCTATTTGGTTTTTTTTTATAGTAAAAATAAAGTGTTGTTAAAACAATTCTAGTTAATTTCGAGAAGTAAGTAATAATTTTAAACAATTTGAAAATAAAGTAATACATTGTTATCTGTATGCTTAATATGTGGAACATGCTAAACATTTCTTGTCTTATCACATCGATTTGGTAACT
Associated Phenotype:
Not determined