Busch Lab

ZMP

tpte

Ensembl ID:
ENSDARG00000056985
ZFIN ID:
ZDB-GENE-030131-5503
Description:
transmembrane phosphatase with tensin homology [Source:RefSeq peptide;Acc:NP_001020629]
Human Orthologues:
TPTE, TPTE2
Human Descriptions:
transmembrane phosphatase with tensin homology [Source:HGNC Symbol;Acc:12023]
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:HGNC Symbol;Acc:17299]
Mouse Orthologue:
Tpte
Mouse Description:
transmembrane phosphatase with tensin homology Gene [Source:MGI Symbol;Acc:MGI:2446460]

Alleles

There are 2 alleles of this gene:

Allele Name Consequence Status Availability
sa41660 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

This allele has been removed from public view.

Allele Name:
sa27609
Status:
Less stringent filtering
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000079549 Nonsense 140 511 7 20

The following transcripts of ENSDARG00000056985 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 25125649)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 24725001
GRCz11 10 24694453
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATAGTAGATGCTTGTATTGTGGTCATTACTCTGGTGGTCACCATGATCTA[C/A]GCATTCTCCGATTTCTCAGGAGCCAGTCTGATTCCCAGGTACAGCCGATT
Long Flanking Sequence:
AACTAAATAACATTTCAATAGTTTGTTTACACACATTTGAAGGTGTTCACCTAAAAATTACAATTGTCATAATTTACAAACCTGTTTGAGCTTTTTTAAGTTGAACACAAATGAAGACTGATGAACAATTGACTTCCATCTTCTTTTTTTTTGTTCCTAATATTGATGGAAGTGGCAGCTTTTTTCCCAATATCTTGTTTTTAAAAGAAGAATAAACTATTAAATTTATTTGTGTGCAAAATTATATTGTTGTGTACATAATAAAGAGTTTATGGCCTATTAAAGCTACATTAAGGACAAATAGTGCAAAACAAGTATAAAGAGTAGTTACTTTGCCTCTAATGTTGTCTTTACATTTCAATTTAAGCTCAAACAAAAGTGTAACAGTCTCTGATAAACTGTTGATCTTTTTTTTTCAGATTCAAAGTGTATTTCAGCTCAAAACTGAATATAGTAGATGCTTGTATTGTGGTCATTACTCTGGTGGTCACCATGATCTA[C/A]GCATTCTCCGATTTCTCAGGAGCCAGTCTGATTCCCAGGTACAGCCGATTTGACCAATACATTAATGTTTGATATTTCCCAACAGTGTTAATGTAACGTTTTGTTATGATGTGTTTTCAGGGTGGTGACATTCCTGAGGTCTCTGAGGATCCTAATTCTGGTACGCATCTTCAGACTGGCCTCGCAGAAGAGAGAGCTTGAAAAAGTCACCAGGAGAATGGTGAGTCACTTAAAAATATAAATACATTATAGTATTATTAAAAATATGTAATTGTTGTGTCTTTTTATCAGATTATAATTCAGTTGCATTATTTTTGTAATTCATTTTATAATAATAATAATAATAATAATAATAATAATAATAATTATTATTATTATTATTATTATTATAACATTTATTTTCAAGTCTCTTTTGCACAGAGGCTGCTTTTAATTGATTGAAAAATTTAGATACTGTAAAATATATTATTACAATTTTAAAAGCAGAATTTACTCCAGTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41660
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000079549 Essential Splice Site 327 511 14 20

The following transcripts of ENSDARG00000056985 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 25131380)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 24730732
GRCz11 10 24700184
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AATGGTTTGCACATGGCTCATTGACAGCGATCAGTTTGAGAGTGCACAGG[T/C]ACAGGCTGATCATATTATCCATATTTCAGATTCCTTCTCTTCCTCAACTG
Long Flanking Sequence:
AAAATAATATATCTGTTTAGCTGGAAGGGCATCCGCTACGTAAAAACGTGCTGAATAAGTTAGCGGTTCATTCCGCTGTGGAGTCCAGATTAAAAAAGAGACTAAGCCGATAAGAAAATGAATGAATATCTGTTTAATAAATCTGTTTTGCTTAATTCACCAAAATGCATTGCCTATATTCACTGGGAAATGCAGAAAATATTCATTTGTACTAAACTATGCTGAGCACTGTATACTGTATATGTAAATATCAATTCTAATTCAACTTATTTGTAGTAGCGGGTCTCTTTAATTCAGCATGAAACTAAATGTTCTTGAAGTTGCTTTGGACCATAACTGTAAAACATTTCTGAAAGTAAAAAGTTAAGACACATTCTAGAAAAACACAAATAAATCAGTGTATGTGAAGTGTGTTATGGTTGATCTTTGTTCTGTAGGTCGTACCGGCACAATGGTTTGCACATGGCTCATTGACAGCGATCAGTTTGAGAGTGCACAGG[T/C]ACAGGCTGATCATATTATCCATATTTCAGATTCCTTCTCTTCCTCAACTGGTCAGATTTTCTTAAAGCCTTACATCTCTCTTCATCTCTCACAGGAGAGCCTGGATTACTTTGGAGAGAGACGGACTGATAAAAGCATGAGCTCCAAGTTTCAAGGTGTTGAAACTCCGTCTCAGGTTTGTTAGCTTGAGTTCAGTCGGTGAACGTGTGTAGAATTATGAGAGGGGTCTGGATGCAGACCTGATGCAGTTGCAAATCTGAGCTGCATGTAATGCTTTATAATGAGCACATCTAACCCATAACCCTACCCCTAACAGTGACGTCACTAGCTTTATTGAGTGCATTGTGTCTGACATTGCTAGCCACAGACTTGCATTTTTAGCTTGCATAATCAAAGCTGCATCCAGATACTATTGAGGATGATAGATGTTCTCTTTATTGATGCATGTTCTGTTGGGTTGTGCATTTGCAGAGCAGGTATGTTGGCTATTATGAGATCAT
Associated Phenotype:
Not determined