ZMP

zgc:55521

Ensembl ID:

ENSDARG00000056832

ZFIN ID:

ZDB-GENE-040426-2828

Description:

Exonuclease 1 [Source:UniProtKB/Swiss-Prot;Acc:Q803U7]

Human Orthologue:

EXO1

Human Description:

exonuclease 1 [Source:HGNC Symbol;Acc:3511]

Mouse Orthologue:

Exo1

Mouse Description:

exonuclease 1 Gene [Source:MGI Symbol;Acc:MGI:1349427]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa17356	Essential Splice Site	Available for shipment	Available now
sa42919	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa17356

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

T > G

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000079390	Essential Splice Site	54	806	None	14
ENSDART00000140022	Essential Splice Site	54	163	None	5
ENSDART00000141523	Essential Splice Site	54	108	None	3

The following transcripts of ENSDARG00000056832 do not overlap with this mutation:

ENSDART00000144038

Genomic Location (Zv9):

Chromosome 17 (position 22402678)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	17	22552827
GRCz11	17	22572663

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

GAGCTTTTTCATGTGCAGAGAAGCTTGCAAAAGGGGAACCTACAGATCAG[T/G]GAGTTGTTTGCATGTANNNATGTTTATTTTTGATTGCAAYAAAATCATGT

Long Flanking Sequence:

GGGAGGAGTTCGTTGTGTTTTGTTTTGGAGGGATTTGGCGGTTAAAATATTACAGACACACAAGTAAACTAAATAACGTTAGCCTAAATGTATTAGAACTCTTTGTATATGGATGTTCGTTATTTTACGTACGTCTTCACGTTTGGACGGTTATTCCGTTGATTTTGGTGACGTATTTTATGTTCAACAGTGAACGTCGTTATGTGTACAGTATGCTTTTAATATGCAACGTTACATGTGTTTAAATGATAAGGGACTTTTATTTTCATATTTCAGGGTGACAGGCTGAACTCTTTTAAACCATCTTCCTCAGACATCTGTCCTTCCAGACAGACAACATGGGTATTCAGGGCCTCTTGCAGTTTATCAAAGATGCTTCGGAGCCCATGCATGTGAAGAAGTATCGAGGACAGACAGTGGCTGTGGACACATACTGCTGGCTTCATAAAGGAGCTTTTTCATGTGCAGAGAAGCTTGCAAAAGGGGAACCTACAGATCAG[T/G]GAGTTGTTTGCATGTACCAATGTTTATTTTTGATTGCAACAAAATCATGTAAACATAGCATATATGCCTAACACCATTTTTCATTCTTCATGCTCATATTCTGTGTCCATCAGGTATGTCTCCTACTGTATGAAGTTTGTGGACATGCTGCTTTCTTTTGGTGTTAAACCTATCTTGGTGTTTGATGGTCGTAACTTGCCCTCCAAACAGGAAGTGGAGAAGTCCCGGCGAGAGTAAGAACTCTGCAGATTACTAGAAAGAGTAGTTGTGTTAATTTGATTTGAAATGAAGAATATTTAATGTTTATTTTCACAAACAGGAGGCGACAGGCCAATCTGCAGAAAGGCAAACAGCTGCTGCGGGAGGGAAAGATAACAGAAGCCAGAGAATGTTTTACCCGAAGTGTTAACATTACCCCATCCATGGCACATGATGTCATTAGGGTAAGGTCATTGCAGCTAAAATTTGTTAAAAGTAAAATAAAGATATATACAGTATGT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa42919

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000079390	Essential Splice Site	501	806	10	14
ENSDART00000140022	None	None	163	None	5
ENSDART00000141523	None	None	108	None	3

The following transcripts of ENSDARG00000056832 do not overlap with this mutation:

ENSDART00000144038

Genomic Location (Zv9):

Chromosome 17 (position 22399830)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	17	22549979
GRCz11	17	22569815

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TGGAGGAACCGATCAGAAGAGGGCACTGAAGAGCAGGGCACATGCAGCAG[G/A]TACTAGAGCATGATGGGAAGTATAACACAGCAATCACAAATTACTAAAGC

Long Flanking Sequence:

CAAAACTGCCACAACACAGGCAAGCATTTGGAGCCAGAACTATGAACCAGGTTGCACCAAGCCACAGTCTCCTACCTCCCCTAAAAGACCAACACCCACCCGGGGCAAAGAGAGGATTGTTAGTGTGCAGAGTCTAAAGTTGCCCCAGAGAGAGTCACAGGTGAAAAGACCCCGTGAAGGTAAACAGACTGCAGTGCAATGATTATGAATTTTGACACACGCCAAGCCATGTTTATATCTTATATTCTCTTTTGTTCTCTCCTGAAAGACACAAGTCTCTCTGTGGATGACCTGTTAGAACAGTACACGGCTGGTGTAAAGAGACACTGTCCTGAAACTCAGCCCACAACTAAGCCGCTGACTAATGATAACATGGTTTCTAAGGAGAATCATTGTGGCAGCACATCTGGACCATCTCGTCCTCGAAATCGCTTTGCAACCCTCTTGCAGTGGAGGAACCGATCAGAAGAGGGCACTGAAGAGCAGGGCACATGCAGCAG[G/A]TACTAGAGCATGATGGGAAGTATAACACAGCAATCACAAATTACTAAAGCCTACTGCCAAAGCTTAGTTGTACTATTGCTCAAATTATTCAGGGTTATTATCCATATGGCATTGAATATGTTTTATTACATTTATGGAGTAGCCTGGTAGTTCCCAGTTTAGCCTCTGGTGTGATGATGTTGGTATTTATATCTCAGGTTCTTCTGTCATGATGAATCCAACATAGCAGAGACACAGGAAGACTCAAAACAAGACTCTTCACAGTCTGTGGAGTCTCAAGAGAAGCATGTGTCACAGTCTGGAGGAGACACATCATCACTGTGTGAAGACCCAGAGAGAGAACAGGACAAAGATGAGCCATCTAGCCCACCCGCATCTCCATCTTGCTCTTCCAGGCCTGCTAGTGTGGGTCTTGGGGTCTTCAGCTGGTCAGGGAGCACCAAAGAACTCAATAAATCTGTTTCACATCCAGCCAGAGACAGCACAGAGAGACAGCGGTC

Associated Phenotype:

Not determined