Busch Lab

ZMP

rnasen

Ensembl ID:
ENSDARG00000055563
ZFIN ID:
ZDB-GENE-070209-23
Description:
ribonuclease 3 [Source:RefSeq peptide;Acc:NP_001103942]
Human Orthologue:
DROSHA
Human Description:
drosha, ribonuclease type III [Source:HGNC Symbol;Acc:17904]
Mouse Orthologue:
Rnasen
Mouse Description:
ribonuclease III, nuclear Gene [Source:MGI Symbol;Acc:MGI:1261425]

Alleles

There are 8 alleles of this gene:

Allele Name Consequence Status Availability
sa191 Nonsense Available for shipment Available now
sa13985 Nonsense Available for shipment Available now
sa31863 Nonsense Available for shipment Available now
sa35230 Essential Splice Site Available for shipment Available now
sa17917 Nonsense Available for shipment Available now

Mutation Details

This allele has been removed from public view.

Allele Name:
sa27915
Status:
Less stringent filtering
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089017 Essential Splice Site None 1289 2 31

The following transcripts of ENSDARG00000055563 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 12 (position 14454961)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 13310614
GRCz11 12 13348917
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTTTTAAAGAATATTTCTGTTTATGTCTATATATTTTTTTACATCTATA[G/A]CTTTCTTAAAGATGTCTTTCCATGCTGGCCGTGGATGCCCGAGGGGTAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa191
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089017 Nonsense 142 1289 2 31

The following transcripts of ENSDARG00000055563 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 12 (position 14455396)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 13311049
GRCz11 12 13349352
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCCACCCACTATGCCCTACCCTCCAACATACCCTATGAGCTACCCTCCA[C/T]AACCCCAGCTTCCCCCTCCACCCAGCTTCAACCCAGCTTATGGTCAGCCT
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037
whole organism
ZFA:0001094
quality
PATO:0000001
normal
PATO:0000461

Mutation Details

Allele Name:
sa13985
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089017 Nonsense 698 1289 13 31

The following transcripts of ENSDARG00000055563 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 12 (position 14467625)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 13323278
GRCz11 12 13361581
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGTTCAACTCCAGTGTCATTACTTTCCCMATAATTGTGCAWTTTGGTATM[C/T]GACCTGCTCAGCTTAGCTACGCTGGAGACCCGCAGTAAGTGTGACCGCAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31863
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089017 Nonsense 792 1289 16 31

The following transcripts of ENSDARG00000055563 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 12 (position 14472788)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 13328441
GRCz11 12 13366744
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTTTGCAGCACGCTATGATGCTTCCTGTTCTCACCCATCACATCCGCTA[T/A]CACCAGTGCCTGATGCATTTGGATAAGCTGATTGGTTACATGTTTAAGGA
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa6240
Status:
Less stringent filtering
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089017 Nonsense 847 1289 17 31

The following transcripts of ENSDARG00000055563 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 12 (position 14473656)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 13329309
GRCz11 12 13367612
KASP Assay ID:
554-4633.1 (used for ordering genotyping assays)
KASP Sequence:
GACCATGCTCGCAACTCTTTGTCCAACTGTGGGATACGCCAGCCWAAATA[T/A]GGAGACCGGAAAGTGCATCATATGTACATGAGGAAAAAAGGTTAGCAAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35230
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089017 Essential Splice Site 861 1289 17 31

The following transcripts of ENSDARG00000055563 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 12 (position 14473698)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 13329351
GRCz11 12 13367654
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCAAAATATGGAGACCGGAAAGTGCATCATATGTACATGAGGAAAAAAGG[T/C]TAGCAAATATTCTTGTAAATGTATGTTAGAAAATGTTTTTAATGTAAGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17917
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089017 Nonsense 1279 1289 31 31

The following transcripts of ENSDARG00000055563 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 12 (position 14495599)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 13351252
GRCz11 12 13389555
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCTTCATCGAAAGAAAGTACCGTCAAGAACTGAAGGAGATGAGAAGAGAG[C/T]GAGAGAGACAGGAGAGAGATAGTGATKAAGGATAGAACAGCAGAAAGTGG
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa7692
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089017 Nonsense 1288 1289 31 31

The following transcripts of ENSDARG00000055563 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 12 (position 14495626)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 13351279
GRCz11 12 13389582
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AACTGAAGGAGATGAGAAGAGAGCGAGAGAGACAGGAGAGAGATAGTGAT[G/T]AAGGATAGAACAGCAGAAAGTGGAGAAGGAAAAGCATTTCTTAGGTAGAG
Associated Phenotype:
Not determined