Busch Lab

ZMP

dock8

Ensembl ID:
ENSDARG00000055225
ZFIN ID:
ZDB-GENE-060503-743
Description:
Novel protein similar to vertebrate dedicator of cytokinesis 8 (DOCK8) [Source:UniProtKB/TrEMBL;Acc:
Human Orthologue:
DOCK8
Human Description:
dedicator of cytokinesis 8 [Source:HGNC Symbol;Acc:19191]
Mouse Orthologue:
Dock8
Mouse Description:
dedicator of cytokinesis 8 Gene [Source:MGI Symbol;Acc:MGI:1921396]

Alleles

There are 8 alleles of this gene:

Allele Name Consequence Status Availability
sa13478 Essential Splice Site Available for shipment Available now
sa12347 Essential Splice Site Available for shipment Available now
sa12014 Nonsense Available for shipment Available now
sa21325 Nonsense Available for shipment Available now
sa34432 Nonsense Mutation detected in F1 DNA Not yet available
sa30642 Nonsense Mutation detected in F1 DNA Not yet available
sa8963 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa13478
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099021 Essential Splice Site 54 2090 3 48
ENSDART00000137583 None None 189 None 5
ENSDART00000144637 None 1 2034 1 46
Genomic Location (Zv9):
Chromosome 8 (position 31243932)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 30386658
GRCz11 8 30395890
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATCATACTTTTCACTACTTGCTTTTGATATTATGATGTGGTTTTCTTTCT[A/C]GYCTCAATCATATGAAGCGGTTGAGCCRGTGGACCTGGATGAGTTCCKGA
Long Flanking Sequence:
AGTATACCTGATTATGTGTGCCTGGGCTACCCTGTCGAATGGATTAATCCGAGCGTACTATTTTATGTGTGCCTGGGTTACACTATCAAATGGCATACCTTGTCGAATAGCTTAACCCTAGACTGAATTATTAAGTATTAAGTATTAACTGACTTAATACTAAAAATGCACTCTATGTCTCCATGTAACAAATTATAAAATGTTTCAGGCTGATTAGAAAAATAATCCAGCATATGCCTGAGCAAGTAAATAACATTCAACATATTTGGATGCATGTAAACTCATTGTTGAAGAAATTATAAAATTTTAAAGTAGCACAACTGGGGCACTTTAGGGAATTATATTGGTTAACTGAAATAATAAAATATGATAGTTAATGAATTGTAAAAAATATTTATTAAATTTATTTAGGCAAGAGAAAACTGGCAATACTAATGCTCTTGGACACTCATCATACTTTTCACTACTTGCTTTTGATATTATGATGTGGTTTTCTTTCT[A/C]GCCTCAATCATATGAAGCGGTTGAGCCAGTGGACCTGGATGAGTTCCTGATGTCTCAGCTGCGCAGTGGCGATGCCGAGGTCATGCAGGAGTTGGGTGAGTTTCCTGATGACGACCTGGATGTTGAGCTTGTGGAGAGGGAATGCAGGACCATCCGCCCCACTATTGCTGAGGAAGGGTAAGTGCTGTATCATTCCAGCTGGGGTTGAGGACATCAACCCTTCTGAAAAAAATATGAATAGATGCTTTTTTGGTATTAAATAATAATGCAGGTACTAGTAACGAAGACATAAATCATATGATTGCTCAGATTGTTTTAAAATGAAAATGTATATTAATTTAAAGTTGCAAAAATAAACGTTTTCACCACAAAATGTCATCTTTCTGACAGTTTTTAATTCCAAAAAGGCTTTTTATGGCACAAACTGTTAGTAAATCTGGGCCTATTTATATACTGTTACAATCAATGGTAATAAAAACTTTTTTAGAAAATAATGATAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12347
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099021 Essential Splice Site 294 2090 8 48
ENSDART00000137583 None None 189 None 5
ENSDART00000144637 Essential Splice Site 241 2034 6 46
Genomic Location (Zv9):
Chromosome 8 (position 31234673)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 30377399
GRCz11 8 30386631
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCCTCTCTTTGCAACAATGGCCCTCTATGACCTGAAGGAGAAGAAGAAGG[T/G]CAGTTTCTGATGGTTACTTTAWAAGCTAAGAATAAAATTACAAATATGTG
Long Flanking Sequence:
GTTTAAACACAGTAACAATTTGTTAAATCATGTTTCTAGCTTGGTTCTACTTAGTCTGTTACTTGTAGCATTTTTTCAACATGCTAAAATTATAATTATGTCAAACATGCTAAAAATGAGTTAGCCTGTTACTTGTAGCATTGTATCCACATGTTAAAAAAATAATTTTTAATATTAGCAAAATGCTAAAAGTGTTAAATCAAGTTTCAATTGTTTCTAGCTTGATTCTAGTTAGCCTGTTACTTTTAGCATTGTTTCCATACACACGCTTATGTTAAATTTTTTCTTGTTTTTATTTCATTCTTTAGGTAGAAACACGTGCATCTTACAATTATGGTGTATAAATTGTGCTGATTGTCTTTTCTCTTCATGCATTAAGTGTTATTAAAAATGTATATTCCTTTGAGAGAATATTTCCAATGTCTTTAACAGATTTGAGATTGAAATCGAGCCTCTCTTTGCAACAATGGCCCTCTATGACCTGAAGGAGAAGAAGAAGG[T/G]CAGTTTCTGATGGTTACTTTAAAAGCTAAGAATAAAATTACAAATATGTGATTTCACTGTTGTAGTTTGATCTGTTTTCTTAAGCTGTGGAGACATAATTAATAATTATTCTGCCTGTCAGTGTTCTTCCTGTTTGTCCTCCCACATTCCTTGACTTCAGTCTCTACAATACTGGACTTTAAAGAGAAGCCTTTTCCATAAACAACCATAACAAGTAAATGTTAAAAGAAACAATAGTTATACAAGCATAAATAGGCCTCAAAATAAGTCTGAAGAGTATAAAACAAGGGAACACAAGACATTTAAATACACACAGCCTGTCTTTACCTCAGATTTAAGAAGGTCTTGCAGTGACAGTCATGGATGTTAAGCAATCAGTAATTATACTACGTTTAGATGCAGTGCTGTGTATTTCCATATTAAACAGACAGACTGCAGATATATTTGGGAGGAATATCCTGCATTACATTAATCCTCTTTAGTGTTAGCTTTGACTGAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12014
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099021 Nonsense 872 2090 22 48
ENSDART00000137583 None None 189 None 5
ENSDART00000144637 Nonsense 816 2034 20 46
Genomic Location (Zv9):
Chromosome 8 (position 31219967)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 30362693
GRCz11 8 30371925
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATTGTGTTTATCTACCAGGTACAGGAGGTCTGATGGCTCATCCAGAGGGT[C/T]GATACAGCACTTTAACTCGCACAACGGCCACCACTGTTGGCTTCATGCTG
Long Flanking Sequence:
TGAAATTCTCAATGAGAGCAGAGCGGATATTTTGTGCAAAGACCAAATGGTTTAACAATAAAGCCATTTTTTACAGCCATTTTGCTCAGATTTACCAATGGAGGCGATATTACTGGAGGGCACTGTACATTCTCTTCTGAGTTTTCAGTCTTGGATCATACATGTTCAGTATTGTTAGTTTTAATCTTGTTTTTTGCAGCAAATCTGGCCCAAATTGCGTTTGAGTCAGTGGTGTCGGTCATCAACAGTCTTCACAACAGTCAGGAGCTGGCAAAAGACCATCAGGGCAGAAACTGTCTCCTCGCAACATACCTGTACTTTGTGTTTCGCTTGCCAGATACTCAATATGAAATCCACACCTCAGGTACAGCAGACCCGTGGACCACCAAATGATTTAATTCCTGTTCAGAATAAAAACAGTTTTTGACTCTGAATCTTTTTTTAACTGTTATTGTGTTTATCTACCAGGTACAGGAGGTCTGATGGCTCATCCAGAGGGT[C/T]GATACAGCACTTTAACTCGCACAACGGCCACCACTGTTGGCTTCATGCTGCTGCAGTCACGAATCCGTTCCAGCAGCAACCCTGATATACCAGCACCACTGAGCCCAGAGGACACAGAGGTCAATAACATTCTAGGAAAGGTACTGTACATATACACGCATGCAACATACTGGGCTTGGGTAAAATACATTGAAAACAGGATGTTGAATTCTATTATATTAAATTTATATTATATTATATAATTCATTTTTAATAAAAATACCCACTGCGCCATCATTATTACAATCATTATTATTATTATTATTATTTTTTGCAATGTAATGTAATGATTTTGCTTTAATTTTAGGTTGCTAATTAGAATTACAATAATACAAACTATACAATTGTATTTATTTTATTTATTTTCTATTAAGGGGTGCATTTCCCGAATAAGGACATAACTTGTGGCTGAGCTCTCATCTATCATAGTATTATGCATTGTTTGGAAAAAGAATGATGTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21325
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099021 Nonsense 1456 2090 35 48
ENSDART00000137583 None None 189 None 5
ENSDART00000144637 Nonsense 1400 2034 33 46
Genomic Location (Zv9):
Chromosome 8 (position 31204252)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 30346978
GRCz11 8 30356210
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCAGGCAGTTCCTCTGGCCGACTGTAAGGATAATGTGGTTGGCGGAGTGT[T/A]GAAGGTTTTGCTGCACTCGCTCACCTGTAATCAGAGCACCACCTACTTGT
Long Flanking Sequence:
TTGTTTAGCTGTTTTCTAAATATGTCCTGTGTTGGCTGTGCAGTGCAAGGTAACGACCGGACACTGGGTCTGAGAGAGAACCTACGCTGGAGGAAAGACCTTACACAGTGGCGCCAGACAAACGACAGGCAGGACAAGTGAGCGTAAAATAGTACCATCATTTCACGCTTCATGTCCATTCAACCTGCGGCACTTCTCATTTTTATAGCCGCTGCTAGTTCTCAGCTGCAGCTCAAATTGGGCTTTGCTAACTGTCTTCTTGTTGCTGTTTCTTCAGATCCAAAGCAGAGCTGGATCAAGAGGCCATAATCAGTGGGAATCTGGCGACTGAGACCAACCTCATAGTGCTGGACCTGCTGGAGATGATCGTACAGGTGACCGTGAACTCGTACTGTGGACTTGAATAATGTTTTGGCAGTGCAGAATGAATAAATGTGTGGGGTTTATTTTTCAGGCAGTTCCTCTGGCCGACTGTAAGGATAATGTGGTTGGCGGAGTGT[T/A]GAAGGTTTTGCTGCACTCGCTCACCTGTAATCAGAGCACCACCTACTTGTCGCACTGTTTCAGCACTCTGAGGGCTCTCATTGTCAAGGTACCAGGGGCAGGAATTATTTTTTTTTGTTAAAAGCCTTATATTTACCTCCTTTATGATATGTTTTACCATAAATCCAGTGCCTTTTATGGTATTTTAGGTTTTACTTAAAGGGATAGTTCACCAGAAAATGAAAAAATTACTTTAATTTTTTTTTCCTCCTGCGTCTTTTTTATATTAATGTATTACTTTCTTCTGTAGAACACAAAAGAGTATGTTTTGAAGAATGCTGGTTGTTGGGACCCATTGACTTCCATATTATGGAGAAAAATACTATGGAAGTCAGTGGGGATTTTCCAGAGCAACTTATTTTTTGTGTTCAAGTGAAGTCAATGATAATAGAACTTACTTTTTTTGGGTGAACTATCTCTTTAAATTTAACCAAATACTTTAAACAATCAAAATAAATATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34432
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099021 Nonsense 1615 2090 38 48
ENSDART00000137583 None None 189 None 5
ENSDART00000144637 Nonsense 1559 2034 36 46
Genomic Location (Zv9):
Chromosome 8 (position 31191697)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 30334423
GRCz11 8 30343655
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACAGTATCCTCTCAGATACAGTCAAGATGAAGGAGTTCCAGAAAGATCCC[G/T]AGATGCTTATGGACCTCATGTATAGGTACACAGCTAAACCCAAGTCTGCA
Long Flanking Sequence:
CCTTAATGCAAGCCTAAACCTAACATAAAATGTAAAAATCTCATTGACTGATTGGAACAATGCTCAAGGGTCAACATAATTGTTAATTCATTAACAGATCCTACTTGGTGAAATCCCGCTAACCCCAGGATTTTGCCCTTAGGAGCAGGATTTTACACACCTGGCCTAAAGTTTTTAGATTAGGAGAGCCCAATACTGTTTCTGGAGATCTGCCTTCTTTCAAAAGTTCAGCTCCAAACCAAAGTAAACATACCTAAATCTTTTAAATAAGATCACAAGGAGCAGTTGATATTTACAGACAGAAATGTTGAATCAGGACTGGAATTGAAGGTGTGTAGATCCCCAGAAAGAGGATTGAACACTCCTGGTGTAGATCTTTAGTCATCCAACCAATCTATTGTAATGAAATACCTCTATCTTAACAGGTAGATGAACTCCTGAGGAACCTAAACAGTATCCTCTCAGATACAGTCAAGATGAAGGAGTTCCAGAAAGATCCC[G/T]AGATGCTTATGGACCTCATGTATAGGTACACAGCTAAACCCAAGTCTGCATCTGCCTTTGGGATCCCAGGCCTGTGGTTTTCTTCTCTGCTTTCCATTTGACTGTGGTTTCTACTGTTTGTCTACTGTTTTTGGACTCACCATGGAAACCGAGTGGCACATTTGAGCCCCGCAGTGTGCCTCACATGTGCAATAACTTGTGTGAATATGCCAGTCCACACTGTTCTTTTGATATTAGGAACAAAATGTTGTTTATTTGCTCAGAGCATTAACCTATGGTTTGCTTTGGCTCCAGGATCGCGAAGGGCTACCAGACTTCTCCAGACCTGCGTCTAACCTGGCTTCAAAACATGGCAGAGAAACACAACGGCAGGAAGTGCTTCACTGAGTCGGCCATGTGTCTGGTTCACGCCGCAGCCCTGGTGGCTGAATATCTCAGCATGCTGGAGGATCACAAATACTTGCCTGTGGGCAGCGTCACCTTTCAAGTGAGTTATTATC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa30642
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099021 Nonsense 1858 2090 44 48
ENSDART00000137583 None None 189 None 5
ENSDART00000144637 Nonsense 1802 2034 42 46
Genomic Location (Zv9):
Chromosome 8 (position 31187036)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 30329762
GRCz11 8 30338994
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGCCTGTGACAAAATGTGTTGATTTTTGCATTTCACACCAGGCGTACATA[C/T]AGATCACCTTTGTGGAGCCTTACTTTGACGACTATGAGATGAAAGACCGC
Long Flanking Sequence:
GATATCCCACCGGCTCGAGGTGAAATTTCTCTGGAAACCTGTGAAGTTCTGAAATCCGTTTGCGATTAAAGATAAATTGTGAAGTTTGAAGTATTTCTTAACTTTTCAGTCAGATGTTTTGATCGTTTTAGAAGTCTAATGTGGTCTGACATTTTCACTCACGTTTTGTTTGACCAAGACTTCTCTTTGTCTTCTACTTTTGCAGAACTTCTACAGTCAGTGCTTTGGTGATGGCGTTTTGGAAATGATTAAAGATTCCACACCAGTAGACCGAAACAAGCTGAGTCCCAACAAGGTACTTCTCATCAAATGTCCTGCCAATGTAAACACGATTACAAACGAAAGCTTTCTTCAGTGTGACCCTCATTAGCCTTGAAAGTCTGTCAGCAGTCAAATCTCCGTTGCCTCATTTAACTAATGTTACCTTTAGCGATTTATGTTTCCTTTAAGTGCCTGTGACAAAATGTGTTGATTTTTGCATTTCACACCAGGCGTACATA[C/T]AGATCACCTTTGTGGAGCCTTACTTTGACGACTATGAGATGAAAGACCGCCTCACCAACTTTGAGAAGAACTTCAACCTTCGCCGCTTCATGTACACCACGCCGTTCACAAAGAGTGGGCGGCCCAGAGGAGAACTCAACGAGCAATACAAGCGGAAAACCATCCTTACCACTATGCATGCCTTCCCCTACATCAAAACACGAATTAACGTCATTCAAAAGGAGGAGGTAATGAGCATCTGGATACAATACTCCATTCTTTGCTTCATCTGCAGGGCTAGTTTGAGAACTGTGTCTAACCTGTATAGAAATCTGACATATGGCAATATATGCTAATTACCTATGATATACAAATTCATGTTTTCATTTCACATAGATTAAATATGTCATATATGCAACATGTATTTCAAAACATTGCAAAAGTGGCAGTCTGCATACAATCTGTTCACATAGTTTCATCTGTTGGAATTACAAATATGTTCATACATGTTCAAATTCACT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8963
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099021 Essential Splice Site 1934 2090 45 48
ENSDART00000137583 Essential Splice Site 37 189 2 5
ENSDART00000144637 Essential Splice Site 1878 2034 43 46
Genomic Location (Zv9):
Chromosome 8 (position 31183969)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 30326695
GRCz11 8 30335927
KASP Assay ID:
2260-0768.1 (used for ordering genotyping assays)
KASP Sequence:
TTTTAGGATGATGWATACAAAAANTGAATTTTCTCTCTTGACATGTTTTCA[G/A]TTTGACCTCACACCAATCGAGGTGGCCATTGAGGACATGCAGAAGAAGAC
Long Flanking Sequence:
TATCTTTTTTGTGTGTCCAAAGAATGAAGAAATTATGATAACCAGATTTTTGGCTGTATTGTCTCTTTAACATTTGCTTTTTCTTTTCCTTTTAATAACAATGAGAGTACACAAAGTACTCCTGTCAGGGTTCTGCCACTCTGGTCTTGTAAATTCTTGTTGTGGTGGCAGAGTCCGGACACTGGCCCTGTCTTGTCCTGTTTCTGTCATTGTGTGTGTCTCTGGGTGCCTCGGATGCGTGCGTTCTTGTACTCGTATTTGTGTTTTGTTCTGTCAGCATTGCGCTGCTTCATTCTCAGCGTCTCCGTCTAGTTGGTTTCTGTTTTGGTTGGCACTGAGATGAGACACCCCGACCGTGACAACTCCATTTTGGTGGCATTTGTTTATTTCTTTGCCCGCAATATGGATTTGAACAGAAAATGGTTCATGGTTTCTGTGGATGATTATTTTTTTTAGGATGATGTATACAAAAATGAATTTTCTCTCTTGACATGTTTTCA[G/A]TTTGACCTCACACCAATCGAGGTGGCCATTGAGGACATGCAGAAGAAGACCCGAGAGCTGGCTGAAGCCACACACAGGGAGAAACCGGATGCTGTGATGCTTCAGATGGTTCTGCAGGGATCTGTCACAGCCACTGTCAATCAGGTCTGAAACCATTATATACACGACTGCTCTGACTTTTTTTTTGTTTGTTTGTTTTTATACACATGATGCAGTGTGGTTGATTGGATCACACGTAGATGAAGGACAACCATTTACATTTACACCTAGTGTTCTAAGTGCCCTAGTGTAGCAAACCATCTACTGTATAAATAATTCATTAATATAGAAATCCAAAGTTCAACAATAGATTTGTCAAATGAAAAATAAATATGCACAAGGATACATTAAAATAATTAAATCCATCTCTTCTGACTAATTTTGACCACTTTCCTGATTTGGGCTAGTCTACATATGGGCTTTTTCTGATGTTTTTATTCAGTGCAATTTTCATTGTGAAA
Associated Phenotype:
Not determined