ZMP
si:dkey-101k6.5
Ensembl ID:
ZFIN ID:
Description:
Novel protein similar to vertebrate transforming growth factor, beta receptor II (70/80kDa) (TGFBR2)
Human Orthologue:
TGFBR2
Human Description:
transforming growth factor, beta receptor II (70/80kDa) [Source:HGNC Symbol;Acc:11773]
Mouse Orthologue:
Tgfbr2
Mouse Description:
transforming growth factor, beta receptor II Gene [Source:MGI Symbol;Acc:MGI:98729]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa9311 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa41488 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa9311
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000077446 | Nonsense | 183 | 590 | 4 | 7 |
| ENSDART00000131738 | Nonsense | 156 | 518 | 3 | 6 |
Genomic Location (Zv9):
Chromosome 9 (position 39626593)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 9 | 38764489 |
| GRCz11 | 9 | 38574284 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACCTGTATCGCACACGTCAGCCAGGCAAAAAGCCCAAGGAATGGGGACMA[C/T]GACGGACCCACTACCAGTCTCTTGATCCTGCCGAGGGCCAAGCTAATGGC
Long Flanking Sequence:
TAGACATACTGTGAAAATTTCCTTGCTGTTAAACATCATTTGGGAAATATTTTAAAAAAAGAAAACTCAAAGGGGGCTAAAAATTCTGACTTGAGCTGTATACAATATGAAGCTTCATTCATATATTAAATATTGGCATTGAAAATAAGCCAAATATTGATTTAACACAAAATAATTTAAAATATTTGACCACTGTCAAACAAAATGTTTACAGCAAACTCTAACGGCTCCAAAACATCTCTTTGCCCATCCAAAACTACCTCTTGTGAAGTAGCATTTAAAATGCTTTCTTTGACAGCAGCTGCATATGGAGTCTGTGTGTGCTAATGTAATCACTTCCCTTTATCCCCTCAGGATTCTCAAAGCTGAAGTCTAAAGACGTGATTCCAGTCGTGGTCATAAGCCTGGTTCCTCCCCTCTTAGTAGCGGTCATTGCGACCATGGCTTTTTACCTGTATCGCACACGTCAGCCAGGCAAAAAGCCCAAGGAATGGGGACCA[C/T]GACGGACCCACTACCAGTCTCTTGATCCTGCCGAGGGCCAAGCTAATGGCATCGACTTTAGTGCCAAGCGGCCATCCCTCAGCGATGACATCAATTCAGAAATGTCATCGACTTGTGCCAATAATCTAAACCACAACACGGAGCAGCTGCCCATCCAGCTGGAGGCGCTGGTGGGTAAAGGGCGCTTCGCGGAGGTATGGCGGGCACGACTTAGTCATAATGAAAGCGGGCAGTATGAAACGGTGGCTGTGAAGATTTTTCCAGCAGTGGAGTATTCATCGTGGTGTAACGAAAGAGCCATATTCTCTGATGCCAACTTGAAACATGAGAACGTGGTGCAGTTTCTGACGGCTGAGGAGCGGGGCGGTACGTCTGCCACCTCCCAGAGGCAATACTGGCTCATCATGGCTTATTATAACATGGGCAACCTTCAAGACTTTCTGGTTGGGAATATTCTGACATGGGCAGAGTTGTGTTCACTAGCAGGCTCTGTGGCAAGA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa41488
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000077446 | Essential Splice Site | 412 | 590 | 5 | 7 |
| ENSDART00000131738 | Essential Splice Site | 385 | 518 | 4 | 6 |
Genomic Location (Zv9):
Chromosome 9 (position 39620185)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 9 | 38758081 |
| GRCz11 | 9 | 38567876 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGGTAATTCAATTTGAGGAAGTTTCGAATCACATGGTCTGTGTTCGTCTA[G/T]GTGGGAACTGCCCGCTATATGGCCCCAGAAGTTCTGGAGTCCAGGGTGAA
Long Flanking Sequence:
TAGAGAAGGGATGTAAAATGTGCATTATGATAAAATCAAAGTATATAGTACATGCACTATTAACTAAAAACTAAACCATAATAGGGGTACTTAAAAGATGTGGACTGAACCCAAACATCTAAACATTTCTAATTCAACATTTTTGTGTGCTTTCCTCACCATCTTTAGGGACTATGTTTAGACCACTTAAGCAGAAATTTTGACTAAAAATAAAAAGGTTAGAAGCCAGTATAGTCACCCAAAACACCCATGTAATGTCTGCATAGTTTCCAGAAAGAGAGCTTCAAACGTTCACAGAAAACAGCCATTCCAAAACAGATCAATGAAAGTATGATCTGAGTGGGAAGAACTGCAGCAGGCATGAAGATCAATTCTTCAAGCTCTCTCAGTGCAACCTAAAAGCTCTGTGGTTGATTTGTAAAGGTCATGGATTTAATCACATTACACCAATGGTAATTCAATTTGAGGAAGTTTCGAATCACATGGTCTGTGTTCGTCTA[G/T]GTGGGAACTGCCCGCTATATGGCCCCAGAAGTTCTGGAGTCCAGGGTGAATCTCGAGGACCTGGAGTCCTTTAAACAGATTGATATCTACTCCATGGCTCTAGTGATGTGGGAAATGGTCTCTAGGTGTGACGTCATAGGAGGCAAGTAAAGCTCTCGATGCATATATTCTCTTGAGGTTAAAACCACGCCATAATGTTATGAAGTATCTGTTTGGTTTTCAACAGAGGTAAAGAGTTACGAACCTCCATTTGGCTCCAAAGTGTGTGAGCAGCCGTGTGTGGACAGCATGAGAGACCTGGTGTTGAGAGACCGAGGAAGACCAGATATTCCAGACAGCTGGACCACACATTCAGTGGGTGCACAATTATAACTGTGGATTTATGAAGTGCAAAACACTGGGTTATATATGAATATTTGAATGTCATTTTTAAGCAGCACTGTAGGGTTTTTTTTACATTAAAATTATGTCTAAAATGATTTCAGTGGTAGAATAACTTT
Associated Phenotype:
Not determined