Busch Lab

ZMP

dgat1b

Ensembl ID:
ENSDARG00000054914
ZFIN ID:
ZDB-GENE-040718-158
Description:
diacylglycerol O-acyltransferase homolog 1b [Source:RefSeq peptide;Acc:NP_001002458]
Human Orthologue:
DGAT1
Human Description:
diacylglycerol O-acyltransferase 1 [Source:HGNC Symbol;Acc:2843]
Mouse Orthologue:
Dgat1
Mouse Description:
diacylglycerol O-acyltransferase 1 Gene [Source:MGI Symbol;Acc:MGI:1333825]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa42756 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa2838 Nonsense F2 line generated Not yet available
sa39109 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa42756
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000077185 Essential Splice Site 343 507 12 17
ENSDART00000147890 None None 78 None 3
Genomic Location (Zv9):
Chromosome 16 (position 33284235)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 31022750
GRCz11 16 30980677
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCAGGAAATGGACTACACTAGAATGACAGAGCGGCTGCTTAGGCTGGCAG[T/A]AAGTAAAACAAACTTTAGGGTCAATGCATTCTCCTCAGAATAGAAAGTGT
Long Flanking Sequence:
GGAATATATGAGGGTAATTTTTATTTATGAAAGTGCTTCTTGTTAGAGCATTACTTGCAGTTAAAGCTGTTGCAAATTACACATTTAATTCACTCACGCACACACATACACACACACACAAAGAGAGACTTCTCTAAACAGCATCGTTAACATTTTTGTTTAACATTTGCTGAGAAATCAAAATCTGTTCCTCTTGTCTGTTACAGTTGCTTCTCACTCAGTTATTGGTTGGTTTAACGCAGCAGGTGAGCATCACATCAAACTTGGCGTTTTCATGTCTTGGAGACATATTTCATATCTAATGCTCTTTCTGTTGTCTTGCAGTGGATGGTGCCAATCATTCGGAGTTCAATGAAGCCATTGCAGGTGTGTTCATGTGCTTTATCTTCTGTTGTTCAGCGCCTTGAGAATAAGCGCTCCATTTAATTCAGTGAAGCGCTTTTTCATCTTTCAGGAAATGGACTACACTAGAATGACAGAGCGGCTGCTTAGGCTGGCAG[T/A]AAGTAAAACAAACTTTAGGGTCAATGCATTCTCCTCAGAATAGAAAGTGTTTTTGCTTAGATCTGGCATGTTTTGATGGAGGATTTGAAACGAGAATCAAATGATGGAATAATTTTTTTTTACACTAGGTGCCCAATCATCTCCTCTGGCTAATATTCTTCTACTCGTTTTTCCACTCCTCAATGAACTTCATGGCTGAGCTGTTGAGGTTTGGAGATCGGGAGTTTTACCGTGACTGGTGGTGAGTGATTATTATCCCTTTTGAATGAGACTCAATCGAATCGAGTGTGTTTACCTGGTCAATATAAGCAGATGACAATCAAAATTTCAGATTTTTTTAAATAAATTGTTTTTATAATCTTTAAAATTACAGAAATATACTAAAAAAATAAAATAAAATAGCTTTTATGTGAGATTCCAAGCTTAGACAGATTTTGCACCGTCAGCTAACTTCACAACCCAATCATCAGTGTCAAAAATTAAAAAATGTTGAAAGGAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2838
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000077185 Nonsense 412 507 15 17
ENSDART00000147890 None None 78 None 3
Genomic Location (Zv9):
Chromosome 16 (position 33282146)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 31020661
GRCz11 16 30978588
KASP Assay ID:
554-2578.1 (used for ordering genotyping assays)
KASP Sequence:
GTGCTTCTCTCTCCTGTTTTCAAAGGCACTTTTACAAGCCGCTGCTGAGA[C/T]GAGGTGCCGGCAAGTTACTGAGCCAATCAGCTGTGTTTTTCGCCTCTGCT
Long Flanking Sequence:
CAACAAAAATCCGGTTTTGATGTTTTTAAAATCTGTTAAACCTCTAGTTAGAGTAAATTACAAGCTAATTTGTTTAGCTGTCTATTCAAAGCATAGGACGGTTGTGACCTCTATTTTACAGTTATTGTTTTTGCATTATTATTAAATGAGCAGCTAGAGGTACCACTTCCCCAACATGCTGCATTTGAAAGGCATAAGTCTCAGATGTATTGTGACCCTGTGTTTGTTTCAGGAACTCTGAAACGATAACGTACTTCTGGCAAAACTGGAATATTCCCGTGCACAAGTGGTGCCTCCGGTGAGTGAACGGCAGGTTTGAAAGCGACAACAGACAGCTGTTGAAATACGACACAGTAAAACCCACACAGACTATAATGAAGAGAGACTATAATGTGATCTGTCCACAAGAAATATATGGTTATTTACTGCTCACACTGGCAGCGAGTTTATGTGCTTCTCTCTCCTGTTTTCAAAGGCACTTTTACAAGCCGCTGCTGAGA[C/T]GAGGTGCCGGCAAGTTACTGAGCCAATCAGCTGTGTTTTTCGCCTCTGCTTTTTTTCATGAGGTGAGATGTGCATAAATCACACGTTGTTTTAAATATTCTGTCAGGTCATGGCAAATGAAAGTTAACAGTCTGAGCCGGGTAACAACCTGTGTGAATTATTTCTCATTTTAGAAATGTGCTATTTCTCATAAGCAGTAGCAATACATATTTTAGAGTGTTTACTATTAATATCTTTAAAAAAGTCTAAACATAAAATATGTATAACCTAAACCTTCATGTACCGCTGACTCAAAGTAATCTTTAAAAGCACTATTTATTGAATGTGCGCTTTAACAAAACTAAAAATTTATGTTGTTTTTTTTTTCTTTTAGCGTTAAAATGATTTGATTTGTTTGTGGTTTAAGAAATTTCTTTGACGAAATGTCAGTATATTTAAACAATTTGTCTTTTATTAAATATGTAATCATTTAAATGTATGTCCTATTAAATGGACTATAA
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037
whole organism
ZFA:0001094
quality
PATO:0000001
normal
PATO:0000461

Mutation Details

Allele Name:
sa39109
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000077185 Nonsense 432 507 15 17
ENSDART00000147890 None None 78 None 3
Genomic Location (Zv9):
Chromosome 16 (position 33282086)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 31020601
GRCz11 16 30978528
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCAAGTTACTGAGCCAATCAGCTGTGTTTTTCGCCTCTGCTTTTTTTCAT[G/T]AGGTGAGATGTGCATAAATCACACGTTGTTTTAAATATTCTGTCAGGTCA
Long Flanking Sequence:
CAAGCTAATTTGTTTAGCTGTCTATTCAAAGCATAGGACGGTTGTGACCTCTATTTTACAGTTATTGTTTTTGCATTATTATTAAATGAGCAGCTAGAGGTACCACTTCCCCAACATGCTGCATTTGAAAGGCATAAGTCTCAGATGTATTGTGACCCTGTGTTTGTTTCAGGAACTCTGAAACGATAACGTACTTCTGGCAAAACTGGAATATTCCCGTGCACAAGTGGTGCCTCCGGTGAGTGAACGGCAGGTTTGAAAGCGACAACAGACAGCTGTTGAAATACGACACAGTAAAACCCACACAGACTATAATGAAGAGAGACTATAATGTGATCTGTCCACAAGAAATATATGGTTATTTACTGCTCACACTGGCAGCGAGTTTATGTGCTTCTCTCTCCTGTTTTCAAAGGCACTTTTACAAGCCGCTGCTGAGACGAGGTGCCGGCAAGTTACTGAGCCAATCAGCTGTGTTTTTCGCCTCTGCTTTTTTTCAT[G/T]AGGTGAGATGTGCATAAATCACACGTTGTTTTAAATATTCTGTCAGGTCATGGCAAATGAAAGTTAACAGTCTGAGCCGGGTAACAACCTGTGTGAATTATTTCTCATTTTAGAAATGTGCTATTTCTCATAAGCAGTAGCAATACATATTTTAGAGTGTTTACTATTAATATCTTTAAAAAAGTCTAAACATAAAATATGTATAACCTAAACCTTCATGTACCGCTGACTCAAAGTAATCTTTAAAAGCACTATTTATTGAATGTGCGCTTTAACAAAACTAAAAATTTATGTTGTTTTTTTTTTCTTTTAGCGTTAAAATGATTTGATTTGTTTGTGGTTTAAGAAATTTCTTTGACGAAATGTCAGTATATTTAAACAATTTGTCTTTTATTAAATATGTAATCATTTAAATGTATGTCCTATTAAATGGACTATAAAATGTAATTAATTATTGGCTTATTAGTATTAATCAAAATTGTAATAGTTTAAAGGGTACT
Associated Phenotype:
Not determined