ZMP
zgc:92203
Ensembl ID:
ZFIN ID:
Description:
prolactin regulatory element-binding protein [Source:RefSeq peptide;Acc:NP_001002638]
Human Orthologue:
PREB
Human Description:
prolactin regulatory element binding [Source:HGNC Symbol;Acc:9356]
Mouse Orthologue:
Preb
Mouse Description:
prolactin regulatory element binding Gene [Source:MGI Symbol;Acc:MGI:1355326]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa16879 | Nonsense | Available for shipment | Available now |
| sa2846 | Nonsense | Confirmed mutation in F2 line | Not yet available |
| sa42645 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa16879
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000077182 | Nonsense | 227 | 425 | 6 | 10 |
Genomic Location (Zv9):
Chromosome 16 (position 3178585)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 16 | 2337324 |
| GRCz11 | 16 | 2574990 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTGTGTTTGTGAACGCAGCACATYGTGACGGTRGGCYGTGATTTCGAGTG[C/A]AGCGTGTGGAGCGGAGATCAGCTGGCTGTGGGGTWGTGTTGGCATGAAAA
Long Flanking Sequence:
TTCCAACCCTGCTTCAACACACTTACCTGTAGGTTTCAAACAAAGCTGAAGGTCTCAATTAGTTTGATCAGGTGTGTTTAATTAGGGTTGGAACTAAACTGTGCAGAGCTGCCGCCCTTTTGGAACGGAGTTTGACACCTGTGATCTAGGTGTTCAATTAAATTCATAATGGTCCTTGCTCTTGAATGGGATAAACCCTGGAGTGTTACTGGGGGGTCATTACAAGACTTTTAAACTTTAATAACTTTGATTTAGAGTTCTTGTATTAGCGCAGACTCTTTGATGATGTCTTCAAGCGTATTTCACCTGCTTGGCGCTCTTTATTTGAGCATTTTTAACCTGTGTTTAATTCAAGTGTTCATTTGTTTGTTGTTTTTAATTGTATATTTATTAATGAAATGTTCTTGTGATGAAAATAGCCTTCGTTTCTGACATTCGCCATCATCTGTTTTGTGTTTGTGAACGCAGCACATCGTGACGGTGGGCCGTGATTTCGAGTG[C/A]AGCGTGTGGAGCGGAGATCAGCTGGCTGTGGGGTTGTGTTGGCATGAAAATATGCCTCAGATCACAGAGAAGACGTACCGATACAAGGCATGCAGGCAAGTGTTGCACTTCCCGATACCTGACGCTTTCAAAAGGCTCAGATTTGGGCATCAATATTTTGTTTTCTTTATTAATTTGATTTCTTTATATATTTTTGTCAGCAGAAGAGAATTTAGCCTTTGTCACTGACATAGCATTAAATAAAAATTATATGTGATGTCAGCAGAAGATCAGTGGTTGGGAAATGGTTTTCAAATCAAACAATTTTAGTATTATTTATTTAATTTACATTGAGTTTACACTATTATAATCTACTTTTATATGCAGAGCAATATTGGAGAAGTTAAAGCATTATTATGAGAGCCATTATCCTCTGATTGGCCTTCTGAGCCAATAGGTTCTGGTTGGCCTTCTGAGAAGGTGTGTTCCGATTGGCCAGCTGAGCTGGGGTGTTCTGATTG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa2846
Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000077182 | Nonsense | 239 | 425 | 6 | 10 |
Genomic Location (Zv9):
Chromosome 16 (position 3178620)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 16 | 2337359 |
| GRCz11 | 16 | 2575025 |
KASP Assay ID:
554-2705.1 (used for ordering genotyping assays)
KASP Sequence:
CCGTGATTTCGAGTGCAGCGTGTGGAGCGGAGATCAGCTGGCTGTGGGGT[T/A]GTGTTGGCATGAAAATATGCCTCAGATCACAGAGAAGACGTACCGATACA
Long Flanking Sequence:
TCAAACAAAGCTGAAGGTCTCAATTAGTTTGATCAGGTGTGTTTAATTAGGGTTGGAACTAAACTGTGCAGAGCTGCCGCCCTTTTGGAACGGAGTTTGACACCTGTGATCTAGGTGTTCAATTAAATTCATAATGGTCCTTGCTCTTGAATGGGATAAACCCTGGAGTGTTACTGGGGGGTCATTACAAGACTTTTAAACTTTAATAACTTTGATTTAGAGTTCTTGTATTAGCGCAGACTCTTTGATGATGTCTTCAAGCGTATTTCACCTGCTTGGCGCTCTTTATTTGAGCATTTTTAACCTGTGTTTAATTCAAGTGTTCATTTGTTTGTTGTTTTTAATTGTATATTTATTAATGAAATGTTCTTGTGATGAAAATAGCCTTCGTTTCTGACATTCGCCATCATCTGTTTTGTGTTTGTGAACGCAGCACATCGTGACGGTGGGCCGTGATTTCGAGTGCAGCGTGTGGAGCGGAGATCAGCTGGCTGTGGGGT[T/A]GTGTTGGCATGAAAATATGCCTCAGATCACAGAGAAGACGTACCGATACAAGGCATGCAGGCAAGTGTTGCACTTCCCGATACCTGACGCTTTCAAAAGGCTCAGATTTGGGCATCAATATTTTGTTTTCTTTATTAATTTGATTTCTTTATATATTTTTGTCAGCAGAAGAGAATTTAGCCTTTGTCACTGACATAGCATTAAATAAAAATTATATGTGATGTCAGCAGAAGATCAGTGGTTGGGAAATGGTTTTCAAATCAAACAATTTTAGTATTATTTATTTAATTTACATTGAGTTTACACTATTATAATCTACTTTTATATGCAGAGCAATATTGGAGAAGTTAAAGCATTATTATGAGAGCCATTATCCTCTGATTGGCCTTCTGAGCCAATAGGTTCTGGTTGGCCTTCTGAGAAGGTGTGTTCCGATTGGCCAGCTGAGCTGGGGTGTTCTGATTGGCCACCTAAGACTGTGTGTTCTGACTGGCCAGCAG
Associated Phenotype:
This allele has been associated with this phenotype by genetic linkage analysis and may not be causal.
See FAQs for more info.
See FAQs for more info.
| Stage | Entity | Quality | Tag |
|---|---|---|---|
| Larval:Protruding-mouth ZFS:0000035 |
eye ZFA:0000107 |
decreased size PATO:0000587 |
abnormal PATO:0000460 |
| Larval:Protruding-mouth ZFS:0000035 |
head ZFA:0001114 |
decreased size PATO:0000587 |
abnormal PATO:0000460 |
| Larval:Protruding-mouth ZFS:0000035 |
inner ear ZFA:0000217 |
decreased size PATO:0000587 |
abnormal PATO:0000460 |
| Larval:Protruding-mouth ZFS:0000035 |
melanocyte ZFA:0009091 |
quality PATO:0000001 |
abnormal PATO:0000460 |
| Larval:Protruding-mouth ZFS:0000035 |
pericardium ZFA:0000054 |
edematous PATO:0001450 |
abnormal PATO:0000460 |
| Larval:Protruding-mouth ZFS:0000035 |
whole organism ZFA:0001094 |
hemorrhagic PATO:0002105 |
abnormal PATO:0000460 |
Mutation Details
Allele Name:
sa42645
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000077182 | Nonsense | 276 | 425 | 7 | 10 |
Genomic Location (Zv9):
Chromosome 16 (position 3181087)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 16 | 2339814 |
| GRCz11 | 16 | 2577480 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGTTTGCAAAGGTAGAGGACCAAAAAGATGCTTTAAGGCTGTATACAGTC[C/T]AAATCCCCCACAAACGAGACCGCAAACCCCCTCCATGCTACATCACCAAA
Long Flanking Sequence:
GCCAGAATGGTCTAATTAGTCAGCTGAATGGTGTGTTGTAATTGGAGTTCTGAGACGGTGTGATCTGATTAGCCGGGATGTTCTGATTGGCCAACTGAGCCATTGTGTCCTGAATTTCACACTATTTCACTAAGATAAAACGTTTTCTTTGCATTTGACTTTTGCTTATTTTTTTAAACTGTGATTGAAGTTTGATGAAGAAATATCTTCATGTGTTTATTCAGGTCTGGAGTCTGTTCTTAAGTCCCTCTGGAAGACTAATATATGAAACTTTACTGACTGAAGGAAGAATAATGTGCATCCTAAAGATTTGCATATTTGATGCCAATAAGGTTTGCATGCTTATTGCTGCAGGAAACAGTAGATATACACATGTGAAGGGTCTAGAAGCAGCAAACACGAGTCTGTCCGATGCACTGATGTTCTGTCATTATATTCAATTTAAATTCAGGTTTGCAAAGGTAGAGGACCAAAAAGATGCTTTAAGGCTGTATACAGTC[C/T]AAATCCCCCACAAACGAGACCGCAAACCCCCTCCATGCTACATCACCAAATGGGACGGTCGAGCTTTCCTGCCGCTGCTCACCAAGCCCTGTGGGAATGAAGTGATCTCCTGTCTGACAGCGAGGTAGTGGGGAAATCTCTGTTATTGTTCTTGCATTTGTCTTTATTATTCTGAATTATGATGTATTTGATGTTTGTTTGTTTGTCCTCCTCAGTGATTCGGGGACATTTCTTGGTCTTGGAACTGTGACGGGATCTGTGGCCATCTATATAGCGTTTTCCCTGCAGGTACAAACAACAAAATCAGGGGTCAAAATCAATAACGCACACAAGGGCTGCACAATATATAGTTTCTGCATTGCTATCACAATGTGCGCATCCACAATAGTCACAACGCAAGATTGGCAATGTCAAATCGGGATTATAATCGGCAAGGATCCACGTTTGAGTCACTGCAACATTTAACCAAACTAAAACATTCCTCATTTATATGTGTTTGA
Associated Phenotype:
Not determined