ZMP

aplp2

Ensembl ID:

ENSDARG00000054864

ZFIN ID:

ZDB-GENE-061009-28

Description:

amyloid-like protein 2 [Source:RefSeq peptide;Acc:NP_001116484]

Human Orthologue:

APLP2

Human Description:

amyloid beta (A4) precursor-like protein 2 [Source:HGNC Symbol;Acc:598]

Mouse Orthologue:

Aplp2

Mouse Description:

amyloid beta (A4) precursor-like protein 2 Gene [Source:MGI Symbol;Acc:MGI:88047]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa29087	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa29086	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa29087

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000077125	Essential Splice Site	312	764	6	17

Genomic Location (Zv9):

Chromosome 18 (position 42834763)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	18	44424654
GRCz11	18	44418108

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TGTCATGCCGGAGAAACAGGACGATGACAAAACTCTGCAGGAAGTAGAAG[G/A]TCAGTCTCACGCTGTTTCCTTCATTTATTGCCTTACTGCCACAGTGAGTT

Long Flanking Sequence:

CTCCTCCAAGACTGCCACAGCATCTGCTCAGAATACGGCCTGGTCTAGGATTATAGAGACCTCAGGATAATAAAACCAGACTAAAATAAGCATCGATATATACGTTTATTTTTTTCTAAATTTGAATTTTAACACTGTTTTGAAGCACATTAGTTTATATATATCCTTAAAACTAACAGACTGAAACTGAAATCTACATTTTTTATTTGTTTAACAGCTTCCCTTTAAAAAGGCAGATAGACCCAAAAACATCACTATCACGTGAAATGTAAAAAATGTTTTCTTTTATCTTAGTGAGCCTGTTGCCATCGATCCTCCCACTCAGGAAGACACAGCAGAGGAAGAGGAGGAGCAGGAGGAGGATGGAGATGAAGAGGACTATCACTACATCTACGAGGATGAGGAGGAGGACAGAGACAGCGAGGAGAAGGATGTTAAGAAAGAGAAAGCTGTCATGCCGGAGAAACAGGACGATGACAAAACTCTGCAGGAAGTAGAAG[G/A]TCAGTCTCACGCTGTTTCCTTCATTTATTGCCTTACTGCCACAGTGAGTTCAATTACAGCAGCTCGTTTGCTTCAGATCTTTGCTCCTGTTCACCATAAGGTTATTGACTTTTTTTTTTAAAGTAAGACTTTGTTTTGTTGTATAGGAATGTTTATGGGTCAAAGATGAGACGTGTTATTCTAGCATCAAAAATGTAGAATTAAATTTTTTCTGTTTTTAATGTTGTATTCTGTGCAGAAATTAGGCTACTTTTTACCATGATTTACAGAAGATGTCCATTTTAATGTAATTTAGGGTAACATTAGTTTAAATAATATATATTAAGGTATTAGCTGTGATTCAAATATAAAAAATGTTAAAGACTCTAAAGGTCAGAGTGCAGCAACCAAATACTGATTTAAATTAATTTAAATCTTTATACTTTGTCATTGTCTTTCAACCCATTTGGGTTTAAATGTTGTTAATCTTTTAAAATATAATCCAATCCGTTGGAGCTCTA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa29086

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000077125	Nonsense	402	764	8	17

Genomic Location (Zv9):

Chromosome 18 (position 42825501)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	18	44415392
GRCz11	18	44408846

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AGACCCCAGCAGATGATAAAGAGCACAGCCGCTTCCAGAAAGCCAAGGAG[C/T]AACTCGAGATCAGACACCGCAACCGTATGGAGAGGGTGAGTGCAGTGTCA

Long Flanking Sequence:

GGTTAAAATGAATTTTTAAATGTAACGCAAGTTACTTTTTATTTGAATTAGTTTGCTTCTAATAAAAAAAAAAAAATTGCTGAATTAAAATTAATATTGAATCACGATGATAGAATGCAATCAAAGAACACATCAAAGAAAAGTGATTTTACTAATAAGACAAAATGTATAAAAGTAGCAAGCACATTGCTTTAAGCTTTCATTAATCTGTATAAACGGCTTGTGTAACTCTGGGGTCAGGTAATTCTCAGAAGATTACATTATACTGAATTATCATTTTTTATGTTATTTGTTTTAAAACGTAACGAAAGAGTTGTCAGTTTGAGCAGTACAGTGCAGCCTGGCTCATATTTGAATCCAAGTTTCAGTGTTTATCATCACTCTCTTTCTGTTTTCCCTCAGCCGTCCCGCCGACCCCTCAGCCCACAGATGATGTGGATGTGTACTTCGAGACCCCAGCAGATGATAAAGAGCACAGCCGCTTCCAGAAAGCCAAGGAG[C/T]AACTCGAGATCAGACACCGCAACCGTATGGAGAGGGTGAGTGCAGTGTCACTTTAATTTTTCGGATATTCTGCATGCAACGTCAAAATTGTTATCCCCCTATGAATATATATCTTTTATATTTCCCAAATTATGTTAAACAGAAATTGGGGGAAAATATACGGGTGGGAGGGGGGTATTAATTATGACTTCAGCTGTATATGGTTATTATTCGTTCTCTATATTAAAACACAAACCAAATATACAGGTTAGTTTTTGCTGTAGTTGTAATTTTTTTAAAACTGAAGAATGAGAGCTTTTGGCCTTTAGTGAAACATGTTGGAGACTCTGTCCTGGTTTGGAGCTGCATTTCTTTCAGTGGCAATATAGTAAACAATAATGATCTTAAACACACGACTATTGCAGTGAAATCATCTGGTGAAACACTCATGAAATGGCCTGCCCAGAATCCAGACCTGAATATTATAGAGACAGTATGGAATCACATGAATTTATTTGACA

Associated Phenotype:

Not determined