Busch Lab

ZMP

si:ch211-89o10.1

Ensembl ID:
ENSDARG00000053804
ZFIN ID:
ZDB-GENE-091116-46
Human Orthologue:
OSBPL1A
Human Description:
oxysterol binding protein-like 1A [Source:HGNC Symbol;Acc:16398]
Mouse Orthologue:
Osbpl1a
Mouse Description:
oxysterol binding protein-like 1A Gene [Source:MGI Symbol;Acc:MGI:1927551]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa37753 Nonsense Mutation detected in F1 DNA Not yet available
sa37752 Nonsense Available for shipment Available now
sa44019 Nonsense Mutation detected in F1 DNA Not yet available
sa37751 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa37750 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa3220 Nonsense F2 line generated Not yet available

Mutation Details

Allele Name:
sa37753
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000053614 Nonsense 34 467 2 13
ENSDART00000142661 Nonsense 34 467 3 14
Genomic Location (Zv9):
Chromosome 23 (position 31190405)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 31025295
GRCz11 23 30951826
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATGACTCGTGTGAAGTCAGCTTTAAAGATGCCTGCGTTTATGCTAACAAA[C/T]AGACGGCGAATGGCAAAGTGCCATCTGAGAATGGAGTATGGGAGAGGCGG
Long Flanking Sequence:
CTATTTAAAATGTTAATAAAATGTCACTTTTACAAACTTTAAGATTGAAAGTTGTTAGAAGAAAGAGCAAGGCCTCATAATGCAATTTAAAAAGCACAAATATATGAAATAAATTATAACAAAAACATGAAATCATAAAATATGGAAAACTGCTAATGTACAGATATTTTTTACAGTAAGGATAAAAAAAAGATTGCCATTTCCAAATTGTTACAATTTTCCATTGTAAAATTAAGCCTGAGGTATTTCTTAGTGCATTTAAATTTTTCCCTTTAGTTTATTAGAGCTGTAATTTATTGAACTATCCATGAGACACACCATAGGACACATTTGAGATTTTTTTTTTACTAATTATATTCATTTTTGTCATGTGTGGCAGTGAAAATGCAACGACACCTCAACCACACATACACAGCTAAATCTCTTCTTCTGTCTTAGGTTTGGAATCGGATGACTCGTGTGAAGTCAGCTTTAAAGATGCCTGCGTTTATGCTAACAAA[C/T]AGACGGCGAATGGCAAAGTGCCATCTGAGAATGGAGTATGGGAGAGGCGGTAAGGTGTCCGAGTAATGTAAAATGATATCCAGTGGCAGGAAACAGAACATGAAGGTTTTTATCTAGTGGAATGTAATGGATTATTGTGTGCCTGTGTTTCAGAACTACTTTGCCAGCACCAATGTTCTCCCGAAATGACTTTAGTGTTTGGGGTTTTCTGAAGAAATGCATTGGAATGGTGAGCACAAGCTAGATTAGCTTTATTCAGACTGTCAATTGAAAACAGATTTGTGCATATGCGTTTGGAAACCAATTATATATAGCGCAAATGTGAATGTCCAAAAAAACAAAAATTTAATGTGATATGTGGTTAAAAATCCTTTCAGTAAATCTTAGTTTTGGGAGTCCACTTGGGTCTGACCAGTTTTTTTATTGATTTTTTTTTTTTGCCTGTCACTATCACTTTGCCCTACGTTTACATTAAATATTTCACACATTGTTTGTAGGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37752
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000053614 Nonsense 216 467 7 13
ENSDART00000142661 Nonsense 216 467 8 14
Genomic Location (Zv9):
Chromosome 23 (position 31183508)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 31018398
GRCz11 23 30944929
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTAAAAAGTGAGACCTTGTTTTAAAATTTGTTATTTTTTATTTCAGGCAC[A/T]GAGAAGCTTACACTTGGACAAACCCCATGTGTTGTGTGCATAATGTTATT
Long Flanking Sequence:
TTTTTATCTTTGCCATGATGACAGTAAATAATATTTTACTTGATATTTTTCAAGACACTTCTATACAGCTTAAGGTGACATTTAAAGGCTTAACTAGGTTAATTAGGTTAACTAGGCAGGTTAGGGTAATTAGGCAAGTTATTGTATAACAGTGGTTTGTTCTGTAGATTATCGAAAAAAAAAAATTAGCTTAAAGGAGCTAATAATTTTGTCCCAAAAATGTTTTTTAAAAAATTAATAACTGCTTTTATTCTAGCCGAAATAAAACAAATAAGACTTTCTCCAAAGAAAAAAAATATTATCAGACATACTGTGAAATGTTCCTTGCTCTGTTAAAAATCATTTGGGAAATATTTAAAAAAGGGGAAAAAAAACAAAAGGGGGCTAATAATTCTGACTTCAACTATACATCTTAAAGTAAGTTCATGTTAACTAAATACTCAAGTATTGCTAAAAAGTGAGACCTTGTTTTAAAATTTGTTATTTTTTATTTCAGGCAC[A/T]GAGAAGCTTACACTTGGACAAACCCCATGTGTTGTGTGCATAATGTTATTCTGGGTAAACTGTGGATTGAGCAGTACGGGACTGTGGAGATTGTCAACCACAGGTAGTTTCCTTTATGTCACTTAAAAATTGACAATGTGTTTTCAGTCTATAGGATTCTCCATCCTATAGATTTCGTTGTGCTCTGTCCAAAAACAATGTTCATGCAGCGAATGGTGTCTTCTCTATTCATTTTAGCACTGGGGACAAGTGTGTGCTGAATTTTAAGCCATGTGGCATGTTTGGCAAAGAGCTGCATCGGGTAGAGGGACATATCCAGGACAAGAGGTGAGCAGTCACTCCTATCAAATGTCAGTGGGTATATCTGGCTCACTGCCTGCCCGGAGAGTTTTACCTCACATCCTCTCTCTGTCTGCAGTGCCGAAGGCATCAGCTGTCTCTTGTATAGCTAGAGACCATATTCACACTTTTACTTTGCCATTTCTGTGTACTTCTTTTCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44019
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000053614 Nonsense 255 467 8 13
ENSDART00000142661 Nonsense 255 467 9 14
Genomic Location (Zv9):
Chromosome 23 (position 31183255)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 31018145
GRCz11 23 30944676
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATGCAGCGAATGGTGTCTTCTCTATTCATTTTAGCACTGGGGACAAGTG[T/A]GTGCTGAATTTTAAGCCATGTGGCATGTTTGGCAAAGAGCTGCATCGGGT
Long Flanking Sequence:
TAGCCGAAATAAAACAAATAAGACTTTCTCCAAAGAAAAAAAATATTATCAGACATACTGTGAAATGTTCCTTGCTCTGTTAAAAATCATTTGGGAAATATTTAAAAAAGGGGAAAAAAAACAAAAGGGGGCTAATAATTCTGACTTCAACTATACATCTTAAAGTAAGTTCATGTTAACTAAATACTCAAGTATTGCTAAAAAGTGAGACCTTGTTTTAAAATTTGTTATTTTTTATTTCAGGCACAGAGAAGCTTACACTTGGACAAACCCCATGTGTTGTGTGCATAATGTTATTCTGGGTAAACTGTGGATTGAGCAGTACGGGACTGTGGAGATTGTCAACCACAGGTAGTTTCCTTTATGTCACTTAAAAATTGACAATGTGTTTTCAGTCTATAGGATTCTCCATCCTATAGATTTCGTTGTGCTCTGTCCAAAAACAATGTTCATGCAGCGAATGGTGTCTTCTCTATTCATTTTAGCACTGGGGACAAGTG[T/A]GTGCTGAATTTTAAGCCATGTGGCATGTTTGGCAAAGAGCTGCATCGGGTAGAGGGACATATCCAGGACAAGAGGTGAGCAGTCACTCCTATCAAATGTCAGTGGGTATATCTGGCTCACTGCCTGCCCGGAGAGTTTTACCTCACATCCTCTCTCTGTCTGCAGTGCCGAAGGCATCAGCTGTCTCTTGTATAGCTAGAGACCATATTCACACTTTTACTTTGCCATTTCTGTGTACTTCTTTTCTGGGATTTGATACTTGCGTTTATGACTCATTTTGTTTGGGTGGATTTCAGCAAAAAGAAGCATTGGGTTATGTATGGGAAGTGGACTGAGTGCATGTATAGCATTGAGCCAAAAGTCTATGAAGCCAACAAGAAAGCGGAGAAGAAGAGCGGAGGAGAGTCCAAGAAACACAAGCAGGTAAAAAAAAATTAAAGCGTGGGTCTGTTATCTCTTACTGTAGAGTCTAGATCTATTTTCTGTTGCTTTTTTGATGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37751
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000053614 Essential Splice Site 362 467 10 13
ENSDART00000142661 Essential Splice Site 362 467 11 14
Genomic Location (Zv9):
Chromosome 23 (position 31180999)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 31015889
GRCz11 23 30942420
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGTAAACTGCTTTGGAGAGTTGCACCTCGACCACCACAATCCACAGAGG[T/A]AAACTCAAGCCTTTAGACTTCAGAAAAACATGGCATTAACATCCGTCTTA
Long Flanking Sequence:
GCATGCTAATGGCATCATGAAAACTCAATTTCCATAAAAAAAATAAATAAATAGAAAACCCTTAATCGTGTGTGTAATCATTAAAAATACACATGTTTGTTGTGAATACGTGCCCTCTAGTGGCCAAAAATATCCTACTGCATCCTTAAGCTTTTTATTCAAATTAAAAGTCATTTAGATTGTTTTTTTCCCCCCATCAAGTGTCCATCTGTCCAAAGTCTTGAATTTACCTTCATAAAACCTGCAGAAATCCTTGTTTTAGCAGTATAGCTATAGACACCATCACAGTAGAGTTTGTAGTTCATTTAGTTTTTTTAGTCTGTGGCATTGTTTATCGGTCTTCTTCAGTGCACTCATGAGACTGTATGCATTTGAATAGGATCAGGGCACTGGAGGTGAAGATGCAGATGAAATGCCTGATGTCCAGGAGACAGTCACTATGATCCCGGGCAGTAAACTGCTTTGGAGAGTTGCACCTCGACCACCACAATCCACAGAGG[T/A]AAACTCAAGCCTTTAGACTTCAGAAAAACATGGCATTAACATCCGTCTTAGGTGACAACTTGAGACTATATCTCGTCTGCAGTTTCAATGCTAGCACTAATGAATATCAGACATTAGCTGCATCCAAAATGGCACACTACACACTATGTGTATGCACTTACACACTCAACACTAAAGTATATTTATGTAGTGTCGTCCCAAATAGAACACTAATGGGTTGTTTTACTAAGTGGAAATTGAAACCGTTTCCCTGATGGCGTTTGACAGTTGCCAATTTAGTGAAATAAATGTCCAAACTACCAAATAACACCTGCCATAAGTATGTCCACATTCACCATCGGGAGGCGCTATAATCTCTCTTATAGGAGAATTTTGCTTTCACAATCCTAAGTAAATACAACATCAGGGCTCAAAAGCTCCACCTCTTCCGCTATGTGAGCAAAGCAGTGGCTGTTGTGTGCGTGAAGTGTCCATCATTCCACACTTCATTTTAACGGTTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37750
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000053614 Essential Splice Site 434 467 12 13
ENSDART00000142661 Essential Splice Site 434 467 13 14
Genomic Location (Zv9):
Chromosome 23 (position 31178948)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 31013838
GRCz11 23 30940369
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAGCGGCTAGAAGAGAGCGTGCTAAAGATGAAGAAGACTGGTCTACAAGG[T/C]AAGCGTTATGTTAAGAGCTGTTTATCCACATCTGTGCATTTTGGCATATT
Long Flanking Sequence:
GTGAAAAAAAATACTGAATTGTTTTTACAAGTGCATGAAAAGGGTTTTAGCTTGCAGCATTTTGCTTTTATTGTCAAGTGTTAATCACTCTTACAAATGCAGACACTTAAACCTGCTAGCTTTGTACTGGAACACTTAAAATCTCTCGTCCTCTTTTCTGGATTTTATTCAGATGTATAATTTTACCAACTTTGCCATGACACTAAATGAGCTCGAGCCTGGCATGACTGAAGTCCTAGCGCCAACAGACTGTCGCCTGCGGCCGGATATTAGAGCGATGGAGAATGGTGATATAGGTATGGACTGTCTCTCTTTTGGCCTGTTCTCTTCCCATCTGTCCATTAAGCTGTCTTGGATGATGCTCTGTTTATTTTAGCCCTAAATTTAGAAGCTCTTCTTAAATTCCAGATTCTGCAAGTCGAGAGAAAGAGAGGCTGGAAGAGAAGCAGAGAGCGGCTAGAAGAGAGCGTGCTAAAGATGAAGAAGACTGGTCTACAAGG[T/C]AAGCGTTATGTTAAGAGCTGTTTATCCACATCTGTGCATTTTGGCATATTGTAGGAATAAAATGGATTAGATTTATTCATTAGGTATAATGAGTTAGACTAAAATCTTAATATTTGTTTTATTATAAAATGGAATTGCACGATACTGGAATTCAGTACCAATTGATGATGAAATATTAATAATGTCCATTTCTCGCTAACATTTGTATGCGTTTATAAATGGTGTTGATTTGCAATTGGGTTCACATGCTCAACAGAAATGACTGTGATTGGCCGTGAAGGTCATTAGTTCACCAAACTCACTGCTGTTCATGAGTGGAACCACAGATACATGAACACTTTAGCTTTTCAAAGTTCTGTTGAATAGCTGACATACAAGCGATCCGCTTATGAAATCACAGCTTTAAAATGCTCCAGTGTCCCTGTATCTGTGGTTACACAGAGTAAAAAGTGGTGATGTAACGAGGAGACTGACACGGAGGGATCCATTTTGCAGTATTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa3220
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000053614 Nonsense 435 467 13 13
ENSDART00000142661 Nonsense 435 467 14 14
Genomic Location (Zv9):
Chromosome 23 (position 31176435)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 31011325
GRCz11 23 30937856
KASP Assay ID:
554-2776.1 (used for ordering genotyping assays)
KASP Sequence:
ATGAGTTKAGTTTTAGATTCTTAACTWTTTTGGCCTCCTGTTTTCAGATG[G/A]TTCCAGCAAGGCAATAATCCGTACACTGGAACCGCAGACTGGATCTACAA
Long Flanking Sequence:
TTTCATTGAATAAAAGTAAAACTGGGATCACCTCAACTGTTTTGCACTTGAGCACCTCCAAGTGGTGTTTACTGGAACTTCAGTCGCTCTGCGCATGTAAACAAAAATGCCAATCTAATTGAATAGACAAAAATAACGATCCTGAGGCATTTCTTTAAAAGTGACGCTTTTATGACTGGTATTTGGTGTGCACAATCACATTGGTGCCCTTTATTTAGTCATGAGGTGTTAAACGTCGACGAAAAACACGAGCATGAACCGTACTCAGTGTGAATGGGCTTTTACCCTCAAAATACTTACCCAAAAGTTATCCCAAGCCTATACAAGTTAGATTTTTCTGTTGAACATTGATGATTAGGAGAATCTTGGTAATTAGACAGTTAATAGTGGGTGTTTCTGGGGGGGGGTGTCTATTTTTTTATTTTTTGTCTTTTTTTTTTGAAGAATTGGATGAGTTGAGTTTTAGATTCTTAACTTTTTTGGCCTCCTGTTTTCAGATG[G/A]TTCCAGCAAGGCAATAATCCGTACACTGGAACCGCAGACTGGATCTACAAAGGTGGTTATTTCGACAGGCGATACTCAGAACTTCCAGACATCTACTGATTGAACTGAGAAGACTGAAAGAGGCTTGAGATTTCATTATTTCACTCAATCCATATCATCTCCTCTCCTTAAGCTCTTATTTTTCTTTTTGTTTGTCTTTGTTGTAATGTGACATTCATATGAACAGTTTTTTTGGACAAAGCCTCTCCACCACTTTTACTCTTCACTCGAATCTGGAAATTCAGAGCGAATGGATTTTATTTATTTTGAGAGGTAGGGAATGCCTTTTTCACTTTCTTTTTTGGAATGGATGTTAGATTTTGAGTTAAACATTCTGCGCAGACCTCAATACATGTAGAAATCGCTAGTTTGTGTGTATGTGCTAAGCTACCTTTCCATGCGTCTCGCTAGTTACACTCAGGTGTTCATTTATGGGTACAAGCGGTTAGTGATGATGGCAC
Associated Phenotype:
Not determined