Busch Lab

ZMP

top3a

Ensembl ID:
ENSDARG00000052827
ZFIN ID:
ZDB-GENE-071212-2
Human Orthologue:
TOP3A
Human Description:
topoisomerase (DNA) III alpha [Source:HGNC Symbol;Acc:11992]
Mouse Orthologue:
Top3a
Mouse Description:
topoisomerase (DNA) III alpha Gene [Source:MGI Symbol;Acc:MGI:1197527]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa10806 Essential Splice Site Available for shipment Available now
sa10899 Essential Splice Site Available for shipment Available now
sa11092 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa10806
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000102492 Essential Splice Site 100 1009 3 19
ENSDART00000102492 Essential Splice Site 100 1009 3 19
ENSDART00000102492 Essential Splice Site 100 1009 3 19
Genomic Location (Zv9):
Chromosome 3 (position 40248307)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 40111667
GRCz11 3 40253525
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTAAACATGACGTCAGTATCAGGGCATCTCTTGGCTCTTGAATTCAAAGC[T/C]CCTTTTCAGAAATGGTAAGTTTTATATACAGTTRAAGYCAGAATTATTAG
Long Flanking Sequence:
CTGTGAATGATGACAGTTTTATTTAATATTCGGAAGAAATGTCACCAGTAGTTGACAGAATAAAATGTTTTACTCTGATTAGGATTTATCTGAATTAACTGTGATTTAGATTATATAACAGCTTAGACCATTAATTTAAACATAGAGCATAAATGAGTCCGACACCCTGTCAGATTTCTCAGAAGGTGTACTTTCAATGGGATGATGTGCAATGAGAAAATTGTGCAAAACTGGCTTATTGGATTTACATTAGCTTAGTCAGTGGCAAGCAAAACTGTATATAACCAAATCACTTAATATCGTTGGCAAAAATGAGTACACTACAGTGAATATGTTAGGAGAAAGTCTGAACAATATTTGAATAAACCAGAAGCATCAAGAAGGTCATGCAAAATATTAAATGTACTTAAATCTTTTGTGTATTTTATTTCTGTTTCACAGAATGTTACTGTAAACATGACGTCAGTATCAGGGCATCTCTTGGCTCTTGAATTCAAAGC[T/C]CCTTTTCAGAAATGGTAAGTTTTATATACAGTTAAAGTCAGAATTATTAGCCCCTCTTTGATTTTGTTTTCTTTTTTAAATATTTCCCAAATGATGTTTAACAAAGCAGAGATTTTCTCAGTTTGTCTGATAATTTTTGTCTTCCGCAGAAAGTCTTATTTGTTTTATTTCCACTAGATTAAAAGCAGTTATTATTGTTTTAAAAACCATTTTAAGGTAAAAAAAAAAATTATTAGCCCCTTTAAGCTTTATTTTTTTTCGATAGTCTACAAAACAAACCATCGTTATACAATAACTTGCCTAATTACCCTAACCTGCCTAGTTAACCCAATTAACTTAGTTAAGCCTTTAAATGTCATTTTAAGCTGTATAGAAGTGTCTTGATAAATATCTAGTCAAATTTTATTTACTGTCATCATGGCAAAGATAAAATAAATCAGTTTTTAGAGATGAGTTATTAAAACTATTATGATTAGAAATGTGCTGAAAAATTCTCTCTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10899
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000102492 Essential Splice Site 100 1009 3 19
ENSDART00000102492 Essential Splice Site 100 1009 3 19
ENSDART00000102492 Essential Splice Site 100 1009 3 19
Genomic Location (Zv9):
Chromosome 3 (position 40248307)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 40111667
GRCz11 3 40253525
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTAAACATGACGTCAGTATCAGGGCATCTCTTGGCTCTTGAATTCAAAGC[T/C]CCTTTTCAGAAATGGTAAGTTTTATATACAGTTRAAGYCAGAATTATTAG
Long Flanking Sequence:
CTGTGAATGATGACAGTTTTATTTAATATTCGGAAGAAATGTCACCAGTAGTTGACAGAATAAAATGTTTTACTCTGATTAGGATTTATCTGAATTAACTGTGATTTAGATTATATAACAGCTTAGACCATTAATTTAAACATAGAGCATAAATGAGTCCGACACCCTGTCAGATTTCTCAGAAGGTGTACTTTCAATGGGATGATGTGCAATGAGAAAATTGTGCAAAACTGGCTTATTGGATTTACATTAGCTTAGTCAGTGGCAAGCAAAACTGTATATAACCAAATCACTTAATATCGTTGGCAAAAATGAGTACACTACAGTGAATATGTTAGGAGAAAGTCTGAACAATATTTGAATAAACCAGAAGCATCAAGAAGGTCATGCAAAATATTAAATGTACTTAAATCTTTTGTGTATTTTATTTCTGTTTCACAGAATGTTACTGTAAACATGACGTCAGTATCAGGGCATCTCTTGGCTCTTGAATTCAAAGC[T/C]CCTTTTCAGAAATGGTAAGTTTTATATACAGTTAAAGTCAGAATTATTAGCCCCTCTTTGATTTTGTTTTCTTTTTTAAATATTTCCCAAATGATGTTTAACAAAGCAGAGATTTTCTCAGTTTGTCTGATAATTTTTGTCTTCCGCAGAAAGTCTTATTTGTTTTATTTCCACTAGATTAAAAGCAGTTATTATTGTTTTAAAAACCATTTTAAGGTAAAAAAAAAAATTATTAGCCCCTTTAAGCTTTATTTTTTTTCGATAGTCTACAAAACAAACCATCGTTATACAATAACTTGCCTAATTACCCTAACCTGCCTAGTTAACCCAATTAACTTAGTTAAGCCTTTAAATGTCATTTTAAGCTGTATAGAAGTGTCTTGATAAATATCTAGTCAAATTTTATTTACTGTCATCATGGCAAAGATAAAATAAATCAGTTTTTAGAGATGAGTTATTAAAACTATTATGATTAGAAATGTGCTGAAAAATTCTCTCTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa11092
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000102492 Essential Splice Site 100 1009 3 19
ENSDART00000102492 Essential Splice Site 100 1009 3 19
ENSDART00000102492 Essential Splice Site 100 1009 3 19
Genomic Location (Zv9):
Chromosome 3 (position 40248307)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 40111667
GRCz11 3 40253525
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTAAACATGACGTCAGTATCAGGGCATCTCTTGGCTCTTGAATTCAAAGC[T/C]CCTTTTCAGAAATGGTAAGTTTTATATACAGTTRAAGYCAGAATTATTAG
Long Flanking Sequence:
CTGTGAATGATGACAGTTTTATTTAATATTCGGAAGAAATGTCACCAGTAGTTGACAGAATAAAATGTTTTACTCTGATTAGGATTTATCTGAATTAACTGTGATTTAGATTATATAACAGCTTAGACCATTAATTTAAACATAGAGCATAAATGAGTCCGACACCCTGTCAGATTTCTCAGAAGGTGTACTTTCAATGGGATGATGTGCAATGAGAAAATTGTGCAAAACTGGCTTATTGGATTTACATTAGCTTAGTCAGTGGCAAGCAAAACTGTATATAACCAAATCACTTAATATCGTTGGCAAAAATGAGTACACTACAGTGAATATGTTAGGAGAAAGTCTGAACAATATTTGAATAAACCAGAAGCATCAAGAAGGTCATGCAAAATATTAAATGTACTTAAATCTTTTGTGTATTTTATTTCTGTTTCACAGAATGTTACTGTAAACATGACGTCAGTATCAGGGCATCTCTTGGCTCTTGAATTCAAAGC[T/C]CCTTTTCAGAAATGGTAAGTTTTATATACAGTTAAAGTCAGAATTATTAGCCCCTCTTTGATTTTGTTTTCTTTTTTAAATATTTCCCAAATGATGTTTAACAAAGCAGAGATTTTCTCAGTTTGTCTGATAATTTTTGTCTTCCGCAGAAAGTCTTATTTGTTTTATTTCCACTAGATTAAAAGCAGTTATTATTGTTTTAAAAACCATTTTAAGGTAAAAAAAAAAATTATTAGCCCCTTTAAGCTTTATTTTTTTTCGATAGTCTACAAAACAAACCATCGTTATACAATAACTTGCCTAATTACCCTAACCTGCCTAGTTAACCCAATTAACTTAGTTAAGCCTTTAAATGTCATTTTAAGCTGTATAGAAGTGTCTTGATAAATATCTAGTCAAATTTTATTTACTGTCATCATGGCAAAGATAAAATAAATCAGTTTTTAGAGATGAGTTATTAAAACTATTATGATTAGAAATGTGCTGAAAAATTCTCTCTG
Associated Phenotype:
Not determined