Busch Lab

ZMP

kpna3

Ensembl ID:
ENSDARG00000052641
ZFIN ID:
ZDB-GENE-030616-541
Description:
importin subunit alpha-3 [Source:RefSeq peptide;Acc:NP_958477]
Human Orthologue:
KPNA3
Human Description:
karyopherin alpha 3 (importin alpha 4) [Source:HGNC Symbol;Acc:6396]
Mouse Orthologue:
Kpna3
Mouse Description:
karyopherin (importin) alpha 3 Gene [Source:MGI Symbol;Acc:MGI:1100863]

Alleles

There are 2 alleles of this gene:

Allele Name Consequence Status Availability
sa24854 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa9826 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa24854
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000074519 Essential Splice Site 128 520 7 17
Genomic Location (Zv9):
Chromosome 1 (position 47175684)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 45987345
GRCz11 1 46678577
KASP Assay ID:
554-7536.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTACCGTTGCCTTAAACATACCAACTTCTATTTCTCTCTCCTTCTTCATC[A/G]GTCCTTCATTGCAGTTTGAAGCTGCCTGGGCTTTGACTAACATTGCATCA
Long Flanking Sequence:
TAAAAGCCAATGTTGAGCGTATTGCATGCAGAGATGTCGTTTTTGTTCACACAGCTACATTAAACATCAACTAGAGTTTAAAATATGATATCATTGTGGACAACAACTTTAAAGGGTACCGCATCTTAAGTGCGTAGTTATTAGGATAATGATTGTACTTCATACACCAATAGAAATCCACCCTAACAACAGTTTTAACTTTCATCTATTTGATCACAAGTTACTGGAAAATTAATGAAACTGCTTTGTGTAATACAGTTGAAGCATTCAGTCCGTCTCAATTCATTACATTCGGTCATGTCTGACTCAAAACAAGCCAAGAAATGCTTCTTTAAAGGTCAATTCCGGTTACAAATACACAATCCTGTGGGAAAGTCCTGCTGAGCTGCTGTATTCAGAGTATTGCAGGCAGTGGTTCTTTATTCAGAGTGGTCAGGGCTGAAATGTTGTTTACCGTTGCCTTAAACATACCAACTTCTATTTCTCTCTCCTTCTTCATC[A/G]GTCCTTCATTGCAGTTTGAAGCTGCCTGGGCTTTGACTAACATTGCATCAGGGACGTCTGCACAGACACAGGCAGTGGTCAAATCCAGTAAGTGGTTCAGACAGAGACTTGAACGGCCTGTTTTGACTTTATCGGCTCCGTCTGTAGTTAAAGTCTCCTGTTGTTCTCTTTAGATGCTGTCCCATTGTTTTTGAGACTTCTGCACTCTCCTCATCAGAATGTGTGTGAGCAGGCCGTGTGGGCGCTGGGAAACATCATTGGTGAGTAACTGTGAAATGTCCTCTCGGTGTTACTAACTCTGAATTTATAAAAAAGGAAGCAAATGTTCAGTGAGTGAGCACTATATGATAATAAGGAGAAAGCTAGACAAACTTTTTTTGCTTTCCTGGCAACAATTGAAGAAACATTGACCAATAAGATTGGAACTTTTTGCTGTCGTGTTCATAGCAGCTGCTGTATGCATATTGACCTCTGCTGGTTCAAATACCATTAAACACCAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9826
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000074519 Nonsense 241 520 9 17
Genomic Location (Zv9):
Chromosome 1 (position 47172853)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 45984514
GRCz11 1 46675746
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTGTCAACCTGTGCCGAAACAAAGACCCTCCACCACCCATGGAAACAGTA[C/T]AAGAGGTGAGCAAAGTGTGTGAYCCCTGTTTGTGCATTTCTGACTCGTTC
Long Flanking Sequence:
TACTTCTCCGTGGTTTAATGATGTAGAAGGAAGAGCGTGTGTGGAGACGCCAACACGGTAAATAACAACAATGACACAAGAAATATGGAGGAAGAAAGTGGTCAGTTACCACAATTTGCTCCCACCAGACCTGAGATCTCAAAGAAATCAGATACAGTATGGTTTTATAAATCTTGGACATTTTAGAAAACAATTTTTCATTTCCAAATGGATGCAAAATATTTAAAAAGTATAACAAAATCCCCATCTTTTGGGTCTTGTAACAGCCGTGATGCTCATCAGTGGTGTGTTTTCTGACATTACTGCACGTGTGTTTGTTTTATGTGCTCTGTGCAGGTGATGGACCTCAGTGTAGAGATTACGTCATCTCGCTCGGTGTGGTCAAACCTCTCTTGTCGTTTATTAATCCTTCCATCCCCATAACCTTCTTGAGAAACGTCACCTGGGTCATTGTCAACCTGTGCCGAAACAAAGACCCTCCACCACCCATGGAAACAGTA[C/T]AAGAGGTGAGCAAAGTGTGTGACCCCTGTTTGTGCATTTCTGACTCGTTCGTGTTGGTAAAAAACGATCCTTACGTCATCCAGTTGAAGATTTTGTAAACGAATTGAATAACTTGCAATACTACAGTAAAAATACTGTAATTTGATTGGCTAAACTGATCCCTTTAGCTGTTTTTTGACTGAATGATGTGTATGAGGCACTTTATAAACTGGTAATTAATTCATTACGCCACCGTTTTCAAAATTTCAACAGATATTATGCATTTCTTTTGCCTTTCAGTTTCGTCCGCAGTAATCTGTCTGTGTGTGTTTTTAGCATCTATTCAGTCAGATATAATGCTGTGTATGCTGCGTGCCAATATTTAATATTGTGCTCATTTCTCTTTTCTGCTATCTGTAATCTGGAGGTGTCGCTTTGAGCTGAAGGGAACATATTGTACCTCCTGCTGCTATGAAATCATTAGACTGTGTTTTCACTCTCTCTGTGTGTGTGATATAGCA
Associated Phenotype:
Not determined