ZMP

pkz

Ensembl ID:

ENSDARG00000052396

ZFIN IDs:

ZDB-GENE-050301-2, ZDB-GENE-050301-2, ZDB-GENE-050301-2

Description:

protein kinase containing Z-DNA binding domains [Source:RefSeq peptide;Acc:NP_001035466]

Human Orthologue:

EIF2AK2

Human Description:

eukaryotic translation initiation factor 2-alpha kinase 2 [Source:HGNC Symbol;Acc:9437]

Mouse Orthologue:

Eif2ak2

Mouse Description:

eukaryotic translation initiation factor 2-alpha kinase 2 Gene [Source:MGI Symbol;Acc:MGI:1353449]

Alleles

There are 5 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa22387	Essential Splice Site	Available for shipment	Available now
sa22386	Essential Splice Site	Available for shipment	Available now

Mutation Details

Allele Name:

sa22387

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

T > G

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000038391	Essential Splice Site	205	511	3	11
ENSDART00000074230	Essential Splice Site	205	448	3	9
ENSDART00000123580	Essential Splice Site	205	489	3	12

Genomic Location (Zv9):

Chromosome 13 (position 51174624)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	13	49885721
GRCz11	13	50198964

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

ATAAGATTGATGACAAGATCTATGCTGTGAAGAGAGTCGAGTTCAACAGG[T/G]AAGTTCACATCATGAGATCATGACTCAACTTAGAATGAACACTCGTGTAT

Long Flanking Sequence:

AACTGACTTCAGTTTCAGGGTGAGTATACTTGACCAGACATGCCACATTAAAAATACTATTTTGGTAAATACTGTAGTGTTTTTTGAACCGAACCGTAGATAATACCATGATAGTCTGTAGTATACTTTAGTTTTACTACAGAAAACTGATGTATTGTGGTATAATATACTCATATTGGGCCATTTGTTTATATTACTACAGTTGTTGTGTTAATTATAAAATCACCACAACAGATTACTTCACTATATACAGTATGGTCTAAAAAACACTTGTGTTGTAGTATAGTATATTTCAGTTATTAAATCAATGTTTTGTTAACAGGGATGATGCATAATGTTACTGCCTATTGCTGTTTGACATGTATCTTCTGTTCTGCAGGATGTCTCAAACTTTTGATGTGATCGAAGAGCTTGGTGACGGAGGCTATGGTTTTGTTTGCAAAGTAAAACATAAGATTGATGACAAGATCTATGCTGTGAAGAGAGTCGAGTTCAACAGG[T/G]AAGTTCACATCATGAGATCATGACTCAACTTAGAATGAACACTCGTGTATTGAGGTAAAGTTGATTTTATGTTCGCACATTAATTTACTGAAACGCTCCCTCGAATTTTGAGTCTGAAATTGCATGTAGATCTGACTTCAAAACAACAATAGCACTATTTAATTGACTGTGGTGTGGACAATGTTGTACTTTGATAGTCATTGGCTGATAATAGGATTTTCCTGTTGAGAATTGGCAAATAGTCCTTTTCTGAACTTACATTTTTGAGGAGAAGGTCAGAATGTGCGAATATAGACCATTTCAATGTGGTCATGTCATAGGCACATCAACATTTCCTACTTGTTAACAAACTGTTTCATAACTTTAACAAGAGGTAATTCAATCATAACTTAACGTTAAAACAGCTATCATAGCATTATTTATCAACAGGAAATATGCTGAGGCCATTGCTTTTGTTTACATCCCTCAAAATGGTCTATAGAACCAACTTTACCCTTATT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa22386

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

T > G

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000038391	Essential Splice Site	449	511	9	11
ENSDART00000074230	Essential Splice Site	386	448	7	9
ENSDART00000123580	Essential Splice Site	427	489	10	12

Genomic Location (Zv9):

Chromosome 13 (position 51167785)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	13	49878882
GRCz11	13	50192125

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GTGGTTTGAAATGCTGTGGAAAATATCTTCTGGGATGGAGAGAGCAGAGG[T/G]CAGTATTGTTTCATTTATAATGTCATTCATTCATTCATTCATTCATTTTC

Long Flanking Sequence:

TGGAATAATTGGTGATTCATTCTGTTGTGGCGACCCCTAGTACATAAGGGACCAAGCTGAAGGAAAATGAAAGAATTTTATATACAATCTATATACAAATGCCGGGTTCCACACAATCAATCTGTGTTAAGAGAACATGAAGGAATTAAGTTATTATTAACTTACTAGTTTTTACCAATTTAAATGGATTTAATGTAAAACAAGATAAGTTCTCCCCCCCAAAAAAACTCAAGAATTGTGTCGCTTCAGCTTATTTTAAATAAGTAGCTTTTTATAGATGTCATTTTTTGAGTGGATAAAAATGTTTAATTAAAATAAAACTGATATGAAATTAATCAAATAAATAATTTTAATGAATAAAGTAAATAAGTAGAATAAATGAAATCTTTTTTTGTAGGAAAATCTGAGGAATTACGATGAAAAGACAGACATTTTTCCCCTTGGACTGATGTGGTTTGAAATGCTGTGGAAAATATCTTCTGGGATGGAGAGAGCAGAGG[T/G]CAGTATTGTTTCATTTATAATGTCATTCATTCATTCATTCATTCATTTTCTTTTTGGCTTATACCCTTTATTAATCTGGGGTCGCCACAGCGGAATGAACCACCAACTTATCCAGCATATGTTCCACACAGCGGACGCCCTTTCAGCTGCAACCCATCACTGGGAAACATCCATACACACTCATACACTACAGACAATTTAGCCTACCCAATTCACCTGTACCACATGTCTTTGGACTGTGGGGGAAAAGCGGAGCACCCTTGTCTTCACAAGAACGCAAGTCCGTTCTCTGCATTCTTGGAGTTGAGAAACAGCCTATGTCTACATGCCTAAATCCATTGTTGCTGCCATGTGATTGGCTGATTAGAAATTTGCGTTAACAAGCAGTTGAAAAGGTTGATATATATATATATATATATATATATATAGATATATATATATATATATATATATATATATATATATATATATATAAAAACACATTTACCGGCCACTTTATT

Associated Phenotype:

Not determined