Busch Lab

ZMP

tmeff2a

Ensembl ID:
ENSDARG00000051824
ZFIN ID:
ZDB-GENE-070912-622
Description:
transmembrane protein with EGF-like and two follistatin-like domains 2a [Source:RefSeq peptide;Acc:
Human Orthologue:
TMEFF2
Human Description:
transmembrane protein with EGF-like and two follistatin-like domains 2 [Source:HGNC Symbol;Acc:11867
Mouse Orthologue:
Tmeff2
Mouse Description:
transmembrane protein with EGF-like and two follistatin-like domains 2 Gene [Source:MGI Symbol;Acc:M

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa34644 Nonsense Mutation detected in F1 DNA Not yet available
sa14883 Essential Splice Site Available for shipment Available now
sa31714 Essential Splice Site Available for shipment Available now
sa41421 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

This allele has been removed from public view.

Allele Name:
sa8338
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000073512 Essential Splice Site 61 370 1 9
ENSDART00000135897 Essential Splice Site 61 379 1 10
Genomic Location (Zv9):
Chromosome 9 (position 25445705)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 24601491
GRCz11 9 24412360
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCCGTCCTCTCTCAGCGACTGTCAGACTCCAACTGGATGGAACTGCTCGG[G/A]TAAGATGTTCAAGTAGCGCTGAAAGKAAAACGGTTTGACGTTTCCTTGGC
Long Flanking Sequence:
GCCCCATTTGTGGTTCTCAAGCCCCCCTTGGCGTATTTTTATTTTTGCCTTGATTTCTGAGCATCTCGCTTACCCACTTTCCTCCCGATACCATCCCCTCCCCTGTCATCGCACCCAGACCTCTCTCATTCCGCATCTGCACCCTCTCGCTTCGGGCGGATCCTCGCTCTTGTCATCCAGAAACAACTGCTTCATGGGGCACATTCCCACCGTCGGAAAATGTCCCTTACTTGGCATTTAAGCGCACCCGCAAAGTTGACAACATTGGGACACGGGCAGTCGTTGCGCGTCTGTGAGCTGTGTTGGGGGAACTGAGATGGGTGTCTCGGTGGCGGCGGCCCTACACGAGCCCCGAAGTCCGCACCAGTGGAGCCGGATAGTGGGACACTGGGTATGGATTGCAGTCTTGTCCTTTCTCGCCACTTTCCCGGTGCAACAACTTGGTGCGTTCCCGTCCTCTCTCAGCGACTGTCAGACTCCAACTGGATGGAACTGCTCGG[G/A]TAAGATGTTCAAGTAGCGCTGAAAGGAAAACGGTTTGACGTTTCCTTGGCTACGGAAAACGGCTGTTTATCATACAAGTCGCATAAGTTACAGACCTAAAATAATGTGTGGTGATGCACGCTTTTGCGGTTCACTGCTGCTAGAAAGATGCTGAAGAGCTGCTTCAGGCAGTCTCCTGCGGGTCTATTTCCGTTACGGTGTAAATAGTTATTTGTTTTCATATTTGACATCTTTTCAAATCGTGCGCTATTGATAGTCTCAATGCCGTAAATAATACATCCCAAGTTAATATTCACCTGAAATGACAGTTGCATGCCGTCGATGTAATCGCTGTTCACTGCAGTAAAGTCGAAACTGTCTGTTATGGTTTTGGATGAGCTATATGGCACGTTCTTGTTCACAGGGATGAAACAATGTTCAGTTTACTAACAGTCGCTGATGCAACATTTCATAAGTGATCAGCTTTTCAAGTTTATTATGTTCAAAAGAAAACAGATAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34644
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000073512 Nonsense 136 370 3 9
ENSDART00000135897 Nonsense 136 379 3 10
Genomic Location (Zv9):
Chromosome 9 (position 25399439)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 24555225
GRCz11 9 24366094
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCTGCGGAGAGACGCCTGCAAACAGCAGACTGAGATCCTGGTTGTGTCT[G/T]AAGGATCCTGTCCAGCCGGTATGTGCATTCGTGTATCCCATGAGTCTGTG
Long Flanking Sequence:
GCTGTATGAAATATGTAGGTCAGTTCCATGCTTAATTATTAGTCTTCTACATTACATCATGTCTTTAAAGAAGGACTTGCTTGTTCCCATTTCATACTGTGCTTACATAAATTGTGAAATTTATTTTTATTAATTGTTTTTATTTCTGAAACCTACTGTTATTTTAACAGTGTCTTATTATTTATTTATTTATTTATTTATTTATTGTGATGTATTTGCATTTATTACATTTTATTCAAAGCAGATAACTCAAAGTTGTGCTATACTATAGACCTGTACTTGCTTGTATCTTATCTAAGTGTTCTGTGTTGCTTGTTTCTTTGACGATTCCACATCTCCCTTGTTTTTTAAAAATGTCTTAATGATTCAAATCTCTTCTTTTTTTTCAGTGCAACAATGATTATGTTCCTGTGTGTGGCTCCAACAATGAAAACTACGAAAATGAGTGTTTTCTGCGGAGAGACGCCTGCAAACAGCAGACTGAGATCCTGGTTGTGTCT[G/T]AAGGATCCTGTCCAGCCGGTATGTGCATTCGTGTATCCCATGAGTCTGTGTTGGTTAATCCACAGCCTAAGCATTTACTCATAAAATGTGAGAATGCAGTTACTTTATCAGGCCAAAAAACTTCAGTCAGACAAAACCTATTAAAGCTTAAACAGGCTAGAACCAGGTATTACTGCTCTGTGTAATGCATTTGATGCATTTTAAAACATAGCATAAAATGCTTTTAACCCTTTTGTCGTGTTGTTTTGTGTATTGTGAGCAGTGGTAAGAAATAACAAATTGCAAATACCCATGTCAAGGGGTAGGGGTGTCCCAATTCTCTTTAGCTTCAAGGCGTAGGGCTAAGGGGAAGGGGTAAATACCCCTTCAAATTAAGATTTTTCAGCTTCACGCTTGAAACCAAAGAGGTACGAAAATTTCCCAGAATACACCAGCCACAACGGCAGGATTGCTGCACCCGGAAGTAAGGAGATCCACAAATTAGTATTTTTTTGTTATTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14883
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000073512 None 244 370 6 9
ENSDART00000135897 Essential Splice Site 253 379 7 10
Genomic Location (Zv9):
Chromosome 9 (position 25289000)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 24444786
GRCz11 9 24255655
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TACAGGCACCAAAGCMGGAGATGGAYAGTATGCCAGGAYAGACTACACAG[G/A]TGGGTTTCATCATTATTATTATATTRTTGGTCACACTTTAYAATAAGATT
Long Flanking Sequence:
AACATCGACTGCTCCCACATCAGTTTTAACCCTGTGTGCGCATCAGACGGCCGTTCATATGACAACCCATGCCAGGTAAAAGAGGCGTCGTGTCAGCGACAGGAGCGCATCGAGGTCAAGTTCCTGGGTCACTGTCAGGGTAAGACTTCAAAAGATTTTTGAGGGCTTACGTAATGAATTGAGCCTTTCTTATGATGTCTTCTTCCATTGAATTTGCATTTATATAAGACAGTGAGTGCATATCATGTAAAGATGAAAATTATAAATCACTGTTATGCAATCAAGTCCCTTCATGTTCATATGATCATTAGTCTCTGGAACAGCACTTACCCAAATATCATCTTTAAAATGGCAATGTACAAATGAAAACATGCTTTATTATGTAACCATCAGACAGAGGACGATCTGCTCTTTTAAAATCTGAATCCTTTATCCTGCAGGCGACATGATTACAGGCACCAAAGCCGGAGATGGACAGTATGCCAGGACAGACTACACAG[G/A]TGGGTTTCATCATTATTATTATATTATTGGTCACACTTTACAATAAGATTGTATTAGTCAATGTTATGTAATGCTTTTACTAACATGAACAAACAATGAGCAATACATTGATTACAGTATATGTTCATGTTAGTTATTGAAAATACAGTTGTTCCTTGTTAGTTTAACTCATGGTGCGTTAACTAATGTTAACAAGTATGTGTTTAAATGTTAATAATGCATTAGTAAATCTTGAAACATGATTAATAATAAATGCTATGCAAGTATTGTTTATATTCAGTTTTGTTAGTAAATACATTAGCTAATAAATTAATCTAATAAATAATAATAATTATTATTATTATTATTCCTATTATTGTTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTACGGAAAGTTTATTTTAACATGGCTGTGAATCTGAAGATGTCCTTGATTTCAGCCATTTTGACCCACTTGTGTGTCTGTGTGTGAATTATAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31714
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000073512 Essential Splice Site 286 370 7 9
ENSDART00000135897 Essential Splice Site 295 379 8 10
Genomic Location (Zv9):
Chromosome 9 (position 25288375)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 24444161
GRCz11 9 24255030
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTTCATGGAGACTGTGAATATCCCAACATGCTCTCAACACCGTCCTGCAG[G/A]TACACACCACTCACACACATTTCTTTGTTTGTGAATGGTGTGAATGTTCC
Long Flanking Sequence:
TCATGTTAGTTATTGAAAATACAGTTGTTCCTTGTTAGTTTAACTCATGGTGCGTTAACTAATGTTAACAAGTATGTGTTTAAATGTTAATAATGCATTAGTAAATCTTGAAACATGATTAATAATAAATGCTATGCAAGTATTGTTTATATTCAGTTTTGTTAGTAAATACATTAGCTAATAAATTAATCTAATAAATAATAATAATTATTATTATTATTATTCCTATTATTGTTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTACGGAAAGTTTATTTTAACATGGCTGTGAATCTGAAGATGTCCTTGATTTCAGCCATTTTGACCCACTTGTGTGTCTGTGTGTGAATTATAGAGGAGAAGCCTGAGGTTTCAGAGGTGGCAAGGGGTCTGTACATCCCCTGCCCTGAGCACTACAAGAACTATTGTGTTCATGGAGACTGTGAATATCCCAACATGCTCTCAACACCGTCCTGCAG[G/A]TACACACCACTCACACACATTTCTTTGTTTGTGAATGGTGTGAATGTTCCATTGTGTTTATAACGTACAAACTGCATTTTGTAAAGCCCTATCACAACCACACTTTTTTTTACTTCATGAAAATCCAAATGTATAAGCCATTTCAAAAATAGGGACATGGGCAATGTTTTTATAAGTCCATCACCTTGCATTACATTTGTTATAACCGTGATTTTAAACACATTTGTGTCCTGACATGTTACAAACACAGACATGTTTGTAGACATGTTTGATGTGTCTGATCAGCCCAGTTTGGCCCATCTTGAAAAACACATTCAGAATAAGTGTTTAAACACAGCTTGTTGTGATTGTGTATGTAACTGTCACAGATCTTTGTCTCCCCCAAGTGTTCAGCAACGAGTGTTTTTTTTTCTTTTTTACCATTGATAAAGACCCACCAAGACATGTTTCATGTTTCTTCTGTCAAAGTTGTTGTCTTTTAGGTCACACTTAATTTTGAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41421
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000073512 Nonsense 315 370 8 9
ENSDART00000135897 Nonsense 324 379 9 10
Genomic Location (Zv9):
Chromosome 9 (position 25285814)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 24441600
GRCz11 9 24252469
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGGAGTATAATGTGCTATATGTGGTGCCAGGCTCTGGAAAGCTCCGCTA[T/A]GTCCTCATCGCGTCCGTCATTGGTGCTCTGCAGGTGGCCATCATATGTGT
Long Flanking Sequence:
TATATATATATATAAAACATGTAGTGCTGCCCCACGCATTATTGCTTGATTTGTACATTGTTTAGAGAAAACATTACACAAATCATTTCTGCAGATCAAGCTGCCACCAAGTTTTTCTTTTTACTGCAAAGCTGCACACATCAGCTTAATAAAATATAATTGGCTATTCAGCTTGTAAAAACTCATATTAAAGTCACAGAAAAGTAAAAGAAAAGAGAAATAATAAGACAGAGAAAATCATCTTGAGCAGTTGCTGCAGTAAAACAGCAGGTGTTTTTGAGGAAAGCCTTTGAGGGCAGGAAACACTGCAGTGAGTGTGTGTATATTACAGAGAGTGTAGACTGTTTAAAAACAAGTAATAGACACCCATGCAATCAAACAAGGATATAAGGGAGTGTTTCCTCTTTCTTCAGCTGTCACTCAGGATTCAGCGGGCCGCAGTGTGACACTAAGGAGTATAATGTGCTATATGTGGTGCCAGGCTCTGGAAAGCTCCGCTA[T/A]GTCCTCATCGCGTCCGTCATTGGTGCTCTGCAGGTGGCCATCATATGTGTAGTGGTGCTGTGTATCACCCGGTGAGTATAAACACACACCACAGCATTATATCGCATGCGCTGTGGAGGAAAGCAGAGGACAGAAACCTCCTGAGTGGATCACACACACACAGCTCTTTATAGAGTGAGAGCTCTTGCCGCCAGGAGTCTGCTAAATAAAACACTTTACACTCTGTGAAAGGTCATTGTGGAAGGGTGTGTGCGCAGTAGTGAAATTTAAATCACCGGCAGCATTAAGTAACTCAAGAATCTACAATGGTATTTACTGTACACCTGAGTGGAGTATTCAGTATGTTCATGGATAATGAGAGATGGGAGAAAAGATTGATGGATGGTTTTTATGCTCTGCTTTCACAGTGTAGACATTTGTCTGTATGGAGTACTGTACCTCTGTGAAGCCCCTTAACAAACAGTGATGGCATGCATGATCATTTTTCCTGTTTTTTAAAT
Associated Phenotype:
Not determined