ZMP
apex1
Ensembl ID:
ZFIN ID:
Description:
DNA-(apurinic or apyrimidinic site) lyase [Source:RefSeq peptide;Acc:NP_998586]
Human Orthologue:
APEX1
Human Description:
APEX nuclease (multifunctional DNA repair enzyme) 1 [Source:HGNC Symbol;Acc:587]
Mouse Orthologue:
Apex1
Mouse Description:
apurinic/apyrimidinic endonuclease 1 Gene [Source:MGI Symbol;Acc:MGI:88042]
Alleles
There is 1 allele of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa11621 | Essential Splice Site | Available for shipment | Available now |
Mutation Details
Allele Name:
sa11621
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000067374 | Essential Splice Site | 140 | 310 | None | 5 |
| ENSDART00000129398 | None | 126 | 296 | None | 6 |
Genomic Location (Zv9):
Chromosome 4 (position 5211244)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 5329425 |
| GRCz11 | 4 | 5337995 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTGGCCATGCTCTGCAAGACCGAACCACTCAATGTCACCTATGGCATTGG[T/C]AAGAGTAACCATGCATGCTYATGTAKTCTCCAAACTGAGTTATAATGCAC
Long Flanking Sequence:
GCAGCAGCGTTTTAGAATGAAAACGGCCTCTCCAGCATTTTCGAAACGCTCCGTTTTCGGCGCTCGAGAACTCCGGCGTAGTGTGGACGGATGGCGTAACCGTAGCAAAACTTATGCGTTTTCAAACTAAAACGCATTAGTGTAAACGGGGCCTATGATAACTGTTATGAGGATTGAATATCAGCACATCTGTATCAGATTTCTGTCACAGTGTAAACATTCAGATGCGTCTGAACAGCCATAAAACAGGCCCTTGTCTCTATGTCTGCGGCTGATTTCTTCTGCTCTGTTGCTGTGTGTTTGCAGTGGGTGCGGAAGGAGGATCCAGACATCCTGTGTCTGCAGGAAACCAAGTGTGCTGAGAAAGCTCTGCCGGCGGACATCACTGGCATGCCAGAGTATCCACACAAATACTGGGCAGGATCAGAGGATAAGGAGGGCTACAGTGGAGTGGCCATGCTCTGCAAGACCGAACCACTCAATGTCACCTATGGCATTGG[T/C]AAGAGTAACCATGCATGCTTATGTATTCTCCAAACTGAGTTATAATGCACTTAAACTAGGTCCTGAAGGGCCGGTGTCCAGCATATTTTAGTTCCAACCCCAATTAAACACACCAGGACCAGCTAACCAAGCATTTTCAAGGTATACTAGGAAGTGTGTGAAGGAAGTTGGAGCTAAACTATGCAGGAAACCGACCCTCCAGGACCAGTTTGGACACCCCTGACTTACAGCAAGCAGCTTTATCTTTCATTAAAGGGATAGTTCACCCAAAACTTAAAAACGTCAGTCATCATTTACTTTAAAAACCTCCGTACGTTTCTAGGTAAAGAGGAGCACGATAAAGAGGGCCGGGTCATCACTGCCGAGTTTCCTGATTTCTTCCTGGTCACGGCGTACGTGCCTAATGCCAGTCGTGGTTTAGTGCGGCTTGACTACCGCAAGACTTGGGATGTGGATTTCCGAGCCTACCTGTGCGGTTTAGACGCGCGCAAACCCCTGGT
Associated Phenotype:
Not determined