Busch Lab

ZMP

mcm10

Ensembl ID:
ENSDARG00000045815
ZFIN ID:
ZDB-GENE-041210-42
Description:
Protein MCM10 homolog [Source:UniProtKB/Swiss-Prot;Acc:Q5RHY1]
Human Orthologue:
MCM10
Human Description:
minichromosome maintenance complex component 10 [Source:HGNC Symbol;Acc:18043]
Mouse Orthologue:
Mcm10
Mouse Description:
minichromosome maintenance deficient 10 (S. cerevisiae) Gene [Source:MGI Symbol;Acc:MGI:1917274]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa31374 Nonsense Available for shipment Available now
sa16502 Nonsense Available for shipment Available now
sa14779 Nonsense Available for shipment Available now
sa8675 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa31374
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067339 Nonsense 96 833 3 18
Genomic Location (Zv9):
Chromosome 4 (position 7046445)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 7857664
GRCz11 4 7866293
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TATGTTTTCCAGCTGAGCTGAAATTAATGCAGGAGAAAATGCAAAAACTA[C/T]AACAGCAGCTGGAGGCCTCACAGAAGACCACACCAGCTCAAAACAAACCC
Long Flanking Sequence:
GATGAGACTCTAATTGGTTTATTCTCAAAACACACCTATAACTCATTAAGAAAATGAACTCAACCCTTTTCGCCCATGCGCCACGGCGCAAAGCAGGTTTTCCCGTCCTTAAATTAGCAAAAATGCGTTCTGACACGCCCTGAAAGCGTTTGCGTCCTGCCTTTTGCGCTCTGCGCATGCACCGTCAAAATAGATCCCATAGACTCCTACGCAGTGTGTAAACCAATAGATTGAAGCTTTCATTTCTTCCTTCCTCTATAATGTACCTGTACATATTAGTACCCGTGTTCTGTGTTTTAAATATTTCATATTTATATGTGGTCTTACATTGTAAACAATGTATCTTTTTAATTGTTTTGTTTTAATTATTTTACTGTCTGCAAGCGTTGTTGCACTTATTTGCCAAAGACAAAAATCCTCTCTGGGACAAATAAAGTTTATCCAATCCTATATGTTTTCCAGCTGAGCTGAAATTAATGCAGGAGAAAATGCAAAAACTA[C/T]AACAGCAGCTGGAGGCCTCACAGAAGACCACACCAGCTCAAAACAAACCCGCCGTCCAGAGACAAAGCACTAAATCCTTAACTTCACCTCAAGCGGGTGTGAAAACTACCCCACCAACAGTACGAGATAGCGATGGCTCTCCATCAAACATCACGGCAAAGCTGAAAAACAAGCAGAGGACGGCCCACCAACCCAAAGCAGGTGAATATCAAGTTACAAGCCTTAGTTTTTAACCTTATGAATTTATTTATTGCAGTTGATGTCTTATCTTTATTTTGTTTTAATTATCACAGACAGGGTTCATACGCATTTTTACTACTAAAATTCAATGACGTTTCCATGACTTTTCCAGGACTTTCAAATCAATTTTCATGACCTAATGTTTCATGTAATGTCTATGTATGTGTGAATAATAATAAGCAAAAAACAGTGCACGTTCAAAGTTATTACAGCATATCATAAATATTTACTTTGAATGAATCTTAATATCTATGTAAAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16502
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067339 Nonsense 421 833 8 18
Genomic Location (Zv9):
Chromosome 4 (position 7040810)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 7852029
GRCz11 4 7860658
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCTTTACAGGCTCCGCCCCTGGTAAAGGAAGGGGGCGGGGCAGTTTGAAG[G/T]AGCGCCTGTGCCAGTCTGATTTCCACTATGGCGGCATGTCAKCACTCGCT
Long Flanking Sequence:
GTAATAAATCAATAAATAAAAGGGAAATATATTACTTATTTTTGATAGACATCACTTTTGCACATTTATATGAATAAACACTTGTGATTTTCAAAATGTTAAATCACTCGAGTAAAACAGTTTGCGTCGTGTGTTCATTTCTAACATCAGTAATGTAGTATTTGTCTCTCTCCAGCTCAGCCTGACAGTGGATCACCCACAGAAAGTCCTCATAATAGGAGAAGCCATGGACTTTGGCACCTGCAAGGCTAAAAAGAAGAACGGGGATTCTTGCACTCAACTTGTCAACTTGGTGAGTCTCCAAACATCAAGCTTTTCTGGGAAAAAGAAAATCCCTGATCAGTTTATTCATTATTTGTTTGTTTGAACAGTATGAATGCCAGTTCTGTCAGTACCATGTTAAAGCCCAATACAAGAAAATGAGCTCCAAGAGGGCGGAGCTTCAGTCCAGCTTTACAGGCTCCGCCCCTGGTAAAGGAAGGGGGCGGGGCAGTTTGAAG[G/T]AGCGCCTGTGCCAGTCTGATTTCCACTATGGCGGCATGTCATCACTCGCTTGTGCGCCCTCAATGTGAGTTTACGGCATCCCATAAACATCACCTCCATCGAAATTCACCCCACAATTAATGCATGAATCTTTTGTTTTTGACAGGTCTGCCCCACAGCCAAAGAAACAACCCACTATACAGTCTGCTTTGGCATCCATCCCAACTAAGAAACTCGGTAAACTCTCTTTCCACCTATATGATGTTTTATACATGTGTTTATGGTTTCTAATCAAGTGTTACGTCTTGTAGTTCTGAACTCAGGTCAGGTGTCAGGCTGTTCAGATGATTTCAGAGGTCTGATGTCTATGCCCACGCCTGGAGCACTTAACATCAAGAGACATTTAGGACAATCCAAGAGTTCAGGTAAGTTTATTCAGTTACAATTCAATTCATGTTTATTTGTATAGCGCTTTTACAATGTTCTCTTAGTAAAGTTCTAGTAAGTTGAGACTACGTCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14779
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067339 Nonsense 438 833 8 18
Genomic Location (Zv9):
Chromosome 4 (position 7040757)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 7851976
GRCz11 4 7860605
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CGCCTGTGCCAGTCTGATTTCCACTATGGCGGCATGTCAKCACTCGCTTG[T/A]GCGCCCTCAATGYGAGTTTACGGCATCMCATAAACATCACCTCCATCGAA
Long Flanking Sequence:
ACTTTTGCACATTTATATGAATAAACACTTGTGATTTTCAAAATGTTAAATCACTCGAGTAAAACAGTTTGCGTCGTGTGTTCATTTCTAACATCAGTAATGTAGTATTTGTCTCTCTCCAGCTCAGCCTGACAGTGGATCACCCACAGAAAGTCCTCATAATAGGAGAAGCCATGGACTTTGGCACCTGCAAGGCTAAAAAGAAGAACGGGGATTCTTGCACTCAACTTGTCAACTTGGTGAGTCTCCAAACATCAAGCTTTTCTGGGAAAAAGAAAATCCCTGATCAGTTTATTCATTATTTGTTTGTTTGAACAGTATGAATGCCAGTTCTGTCAGTACCATGTTAAAGCCCAATACAAGAAAATGAGCTCCAAGAGGGCGGAGCTTCAGTCCAGCTTTACAGGCTCCGCCCCTGGTAAAGGAAGGGGGCGGGGCAGTTTGAAGGAGCGCCTGTGCCAGTCTGATTTCCACTATGGCGGCATGTCATCACTCGCTTG[T/A]GCGCCCTCAATGTGAGTTTACGGCATCCCATAAACATCACCTCCATCGAAATTCACCCCACAATTAATGCATGAATCTTTTGTTTTTGACAGGTCTGCCCCACAGCCAAAGAAACAACCCACTATACAGTCTGCTTTGGCATCCATCCCAACTAAGAAACTCGGTAAACTCTCTTTCCACCTATATGATGTTTTATACATGTGTTTATGGTTTCTAATCAAGTGTTACGTCTTGTAGTTCTGAACTCAGGTCAGGTGTCAGGCTGTTCAGATGATTTCAGAGGTCTGATGTCTATGCCCACGCCTGGAGCACTTAACATCAAGAGACATTTAGGACAATCCAAGAGTTCAGGTAAGTTTATTCAGTTACAATTCAATTCATGTTTATTTGTATAGCGCTTTTACAATGTTCTCTTAGTAAAGTTCTAGTAAGTTGAGACTACGTCAGTCCAGTTTTCAGAGTTGAAGTTCAGTGTGGTTTAACTTTCACTGCTAAAACAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8675
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067339 Essential Splice Site 442 833 8 18
Genomic Location (Zv9):
Chromosome 4 (position 7040744)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 7851963
GRCz11 4 7860592
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTGATTTCCACTATGGCGGCATGTCAKCACTCGCTTGTGCGCCCTCAATG[T/C]GAGTTTACGGCATCMCATAAACATCACCTCCATCGAAATTCACCCCACAA
Long Flanking Sequence:
TATATGAATAAACACTTGTGATTTTCAAAATGTTAAATCACTCGAGTAAAACAGTTTGCGTCGTGTGTTCATTTCTAACATCAGTAATGTAGTATTTGTCTCTCTCCAGCTCAGCCTGACAGTGGATCACCCACAGAAAGTCCTCATAATAGGAGAAGCCATGGACTTTGGCACCTGCAAGGCTAAAAAGAAGAACGGGGATTCTTGCACTCAACTTGTCAACTTGGTGAGTCTCCAAACATCAAGCTTTTCTGGGAAAAAGAAAATCCCTGATCAGTTTATTCATTATTTGTTTGTTTGAACAGTATGAATGCCAGTTCTGTCAGTACCATGTTAAAGCCCAATACAAGAAAATGAGCTCCAAGAGGGCGGAGCTTCAGTCCAGCTTTACAGGCTCCGCCCCTGGTAAAGGAAGGGGGCGGGGCAGTTTGAAGGAGCGCCTGTGCCAGTCTGATTTCCACTATGGCGGCATGTCATCACTCGCTTGTGCGCCCTCAATG[T/C]GAGTTTACGGCATCCCATAAACATCACCTCCATCGAAATTCACCCCACAATTAATGCATGAATCTTTTGTTTTTGACAGGTCTGCCCCACAGCCAAAGAAACAACCCACTATACAGTCTGCTTTGGCATCCATCCCAACTAAGAAACTCGGTAAACTCTCTTTCCACCTATATGATGTTTTATACATGTGTTTATGGTTTCTAATCAAGTGTTACGTCTTGTAGTTCTGAACTCAGGTCAGGTGTCAGGCTGTTCAGATGATTTCAGAGGTCTGATGTCTATGCCCACGCCTGGAGCACTTAACATCAAGAGACATTTAGGACAATCCAAGAGTTCAGGTAAGTTTATTCAGTTACAATTCAATTCATGTTTATTTGTATAGCGCTTTTACAATGTTCTCTTAGTAAAGTTCTAGTAAGTTGAGACTACGTCAGTCCAGTTTTCAGAGTTGAAGTTCAGTGTGGTTTAACTTTCACTGCTAAAACACTGAAGAGTAAATC
Associated Phenotype:
Not determined